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Staff members with discipline Biochemistry & Molecular Biology

Academia develops at the interface of different fields. This is one reason why the University of Groningen is home to a wide range of fields, each with a great number of subject specialists. The overview below, which is based on a standard categorization of fields, will help you find the right expert for each field. If you cannot find the expert you are looking for in this list, try searching via a related field or faculty; you may find him or her there.

Overview of all disciplines

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PhD student
BSc Pharmaceutical Sciences, Alexandria University, Egypt. 
MSc Pharmaceutical Sciences (Pharmacognosy), Alexandria University, Egypt. 
PhD  Pharmacy (Chemical and Pharmaceutical Biology), University of Groningen, The Netherlands.
I.I.A.F. (Ingy) Abdallah, PhD
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Function
Postdoctoral Fellow
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Function
Research Analist
Main interest: issue engineering and use of stem cells in wound repair. Expertise in collagen (connective tissue diseases; fibrosis) and cell/matrix interactions.
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Professor
Structural Biology
cryo Electron Microscopy (cryo-EM)
Membrane Proteins
C. (Cristina) Batista Paulino, PhD
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Function
Assistant Professor, Head of cryo-EM unit
policy/strategy, academic & industrial partnerships, staff development & recruiting, quality management, technology transfer and public relations
dr. J.P. (Jan Peter) Birkner
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Research Manager
V.W. (Vincent) Bloks
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Research Officer
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Degree programme coordinator bachelor and master Pharmacy
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Honorary professor Synthetic Biology and Cell Engineering
dr. S.W.M. (Sophia) Bruggeman
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Function
Rosalind Franklin fellow (scientist, junior group leader)
Transcriptional, translational and post-translational control of gene regulation.
Moelcular mechansims in ageing, lifespan determination and age-related diseases.
Molecular mechanims and metabolic alterations in tumour development.
prof. dr. C.F. (Cor) Calkhoven
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Professor
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Function
PhD student
Molecular diagnostics of infectious diseases -Molecular Biology - Cell biology - Microbiology - Genomics - Next Generation Sequencing - Genotyping
dr. M.A. Chlebowicz
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PostDoc/ MMMio
S. (Shreyans) Chordia, MSc
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PhD student
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Professor of Medical Microbiology
Neurodegeneration, Mitochondrial function, Inflammation, Potassium channels
A.M. (Amalia M.) Dolga, PhD
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Assistant Professor
Membrane biology, Protein translocation and membrane protein biogenesis, multidrug resistance, biotechnology of filamentous fungi and yeast, membrane biology of hyperthermophilic Archaea
prof. dr. A.J.M. (Arnold J M) Driessen
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Function
Professor in Molecular Microbiology
Our group is working at the cross roads of inflammation and neuronal function with molecular, cellular and behavioural approaches in various neuronal disease models.

Background:

Molecular mechanisms involved in neuroinflammatory and neurodegenerative diseases are a result of evolutionary processes like all other biological phenomena. Therefore understanding how these mechanisms may have evolved will eventually lead to a deeper understanding of these processes. We investigate in depths the function of the cytokine Tumor Necrosis Factor in neurodegenerative diseases. This pleotropic master cytokine belongs to a large family of molecules, which are able to induce apoptotic cell death but also proliferation and other cellular responses like tissue remodeling. Apoptosis plays an important role in the elimination of infected or transformed cells but also during embryonic development. TNF was found to play a major role in many neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson's disease, stroke or Multiple Sclerosis (MS) but also in Depression and many other brain diseases. In neurodegenerative diseases apoptosis seems to play a major role and therefore the pro-apoptotic function was for a long time at the center of interest to many researchers in this field. We and others have demonstrated that the TNF and TNF receptor system is mainly a protective and sensory system guiding the tissue response to various forms of cellular stress. Apoptosis is just one of the potential responses, which can be induced by TNF. We are following some of these molecular signaling mechanisms in the brain and specific brain cells in response to TNF and detected various signaling molecules downstream of either TNF receptor 1 or TNF receptor 2 and their neuromodulatory signaling e.g. glutamate receptor function, small conductance potassium channels, cAMP Epac-, PKB/Akt- signaling, Nuclear Factor kappa B or lipocalin-2 and iron metabolism.
prof. dr. U.L.M. (Ulrich L. M.) Eisel
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Associate Professor
Gut microbiota and its interaction with host immune response, metabolism, and gut-brain axis
S. (Sahar) El Aidy, PhD
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Tenure Track Assistant Professor
A. (Arja) ter Elst
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Function
Clinical Molecular Biologist in Pathology
In my lab, we are interested in the consequences of aneuploidy, an abnormal DNA content affecting 2 out of 3 cancers. By understanding how cancer cells make use of the advantages of aneuploidy and cope with the disadvantages of aneuploidy, we hope to get to therapies that can eradicate aneuploid cancers.
prof. dr. ir. F. (Floris) Foijer
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Associate professor
Enzyme engineering, redox enzymology
Corinna Glasner is scientific project manager for the leadpartner of the two INTERREG V projects EurHealth-1Health and health-i-care and research associate at the Department of Medical Microbiology and Infection Prevention. Her expertise lies in molecular microbiology and local, national and international epidemiology of pathogens. She successfully completed her PhD at the end of 2014 with numerous publications on the subtyping and genomic population structure of major pathogens of hospital infections, such as Staphylococcus aureus. Here she led u.a. Europe-wide prevalence of S. aureus and carbapenemase-producing Enterobacteriaceae (CPE). The avoidance of antibiotic resistance and the strengthening of infection prevention are also her area of ‚Äč‚Äčinterest during this time. Since 2016, Corinna Glasner has been a central part of German-Dutch cooperation in the current INTERREG project EurHealth-1Health and health-i-care and is learning and living the opportunities of this exciting border region every single day.
dr. C. (Corinna) Glasner
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Scientific Project Manager
R. Gomez Sanchez
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Postdoctoral researcher
Cell movement
Signal transduction
prof. dr. P.J.M. (Peter) van Haastert
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Professor in Cell Biochemistry
microbial metabolism, systems biology, single cell analysis, modeling
prof. dr. M. (Matthias) Heinemann
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Professor
Applied Biotechnology/Microbiology/Molecularbiology/
Protein X-ray Crystallography/ Proteomics (LC-MS)

Proteomics services are available for institutes and industry  
ing. J. (Johan) Hekelaar
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Coördinator Proteomics Facility (part of GBB institute)
Stemcells in relation to cardiomyopathy
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Postdoctoral fellow
Membrane Biophysics, Fluorescence Spectroscopy, Lipid-protein interactions, Super-resolution microscopy
Enzyme discovery and engineering, biocatalysis, biotransformation, protein engineering
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Professor in Chemical Biotechnology
Understanding chemosensitivity of testicular germ cell tumors, Inducing apoptosis and inhibiting pro-survival to enhance drug efficacy in cancer, Identifying novel drugable pathways in ovarian and cervical cancer.
prof. dr. S. (Steven) de Jong
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Professor
Analytical chemistry. Carbohydrate & enzyme characterization. Protein and DNA analysis, gene expression and protein purification. Plant biomass.
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S.P. (Sebastiaan) van Kessel, MSc
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PhD-Student in Host-Microbiota Group (see projects)
Cell Biology, Biochemistry & Molecular Biology, Microscopy
prof. dr. I.J. (Ida) van der Klei
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Professor
Ion channels, chemical biology, biochemistry, biophysics, electrophysiology, nanotechnology
prof. dr. A. (Armagan) Kocer
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Tenure-Track Associate Professor
Molecular Genetics, Genomics
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Professor in Molecular Genetics
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Associate Professor
Endosomal transport, autophagy, behavioural neurogenetics, genetics, mitochondria, neurodegeneration
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Function
microRNA, endothelial dysfunction, endothelial-mesenchymal transition, epigenetics, Ezh2, MAPK7, Erk5, inflammation, endothelial cell, cardiac fibrosis, atherosclerosis, diabetic retinopathy.
Biology of cancer stem cells: novel therapeutic opportunities
prof. dr. F.A.E. (Frank) Kruyt
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Professor
Biochemistry, physiology of articular cartilage. Knowledge of ways to repair articular cartilage. Cell therapy and Tissue engineering. Extensive and broad experience in Orthopedic Research, from articular cartilage to hip implants and infection of implants.
dr. R. (Roel) Kuijer
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Associate professor (retired)
Bile acids, Cholesterol, Lipids, Nuclear receptors, Fluxomics
prof. dr. F. (Folkert) Kuipers
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X. (Xiang) Li
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PhD student
Molecular Cell Biology
dr. M.H.K. (Maarten H K) Linskens
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Lecturer/ Associate Professor Cell Biochemistry
Mathematical modelling; Origin of life; Metabolic networks
Biotechnology & Applied Microbiology, Microbiology, Food Science & Technology, Intellectual Property and Patents , Applied Biocatalysis, Starch, Carbohydrates
prof. dr. M.J.E.C. (Marc) van der Maarel
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Director Graduate School of Science and Engineering
Electrophysiology, Single-molecule Nanopore Technology
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Autophagy
M. (Mario) Mauthe
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Chemical Biology, Biomolecular Chemistry, Biotechnology, (Bio)catalysis
C. (Clemens) Mayer, PhD
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systems biology, mathematical modelling, machine learning, probability & statistics
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Tenure-track assistant professor
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Professor of Experimental Gastroenterology and Hepatology
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Gene Regulation with emphasis on the control of translation
Molecular mechanisms in life span determination, ageing and age related diseases
Molecular mechanisms in cancer development
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Research Associate
Bioengineering; Tumour microenvironment; 3D cell culture
dr. A.P. (Anika) Nagelkerke
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Assistant Professor
Development and use of biophysical tools to study complex biochemical processes at the single-molecule level.
prof. dr. A.M. (Antoine) van Oijen
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Professor of Molecular Microscopy and Spectroscopy
Computational Physics, Molecular Biophysics, Molecular Dynamics, Applied Physics, Materials Science
nutrient sensing
stable isotope-based fluxomics
transcriptional regulation
metabolic diseases
dr. ir. M.H. (Maaike) Oosterveer
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Young Principal Investigator
dr. H.P. (Hjalmar) Permentier
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Head of the Interfaculty Mass Spectrometry Center
biocatalysis
enzyme cascades
mechanistic enzymology
protein engineering
directed evolution
catalytic promiscuity
synthetic biology
C-N and C-C lyases
prof. dr. G.J. (Gerrit) Poelarends
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Professor of Pharmaceutical Biotechnology
Synthetic Biology, Enzymology, Membrane Biology, Transport and Signal Transduction
prof. dr. B. (Bert) Poolman
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Professor in Biochemistry
in vivo metabolism, stable isotopes, metabolomics
prof. dr. D.J. (Dirk-Jan) Reijngoud
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Professor of Inborn Variation of Metabolism, emeritus
biomolecular chemistry & catalysis
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full professor
Antibiotica
Lanthipeptides
Posstranslationele Modification Enzymes
Peptide Design
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PhD-student
Transfection technology
Targetted delivery
Epigenetics
Genetics
Celbiology
Developmental Biology
dr. M.H.J. (Marcel) Ruiters
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associated Professor
Complex traits Genetics, Complex traits mapping, Genetics in Isolates, Genome-wide association studies, Quantitative genetics, Genotype Imputation Methods
dr. S. (Serena) Sanna, PhD
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Protein expression and purification
Protein crystallization and crystallography
prof. dr. D.J. (Dirk-Jan) Scheffers
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Associate Professor Molecular Microbiology
Gynecologic Oncology
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Inflammation, vesicular transport, lipid metabolism, cholesterol transport, mouse transgenesis, liver disease
prof. dr. ir. A.J.A. (Bart) van de Sluis
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Principal Investigator (Associate Prof.)
Medical biology
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PhD student
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PhD student
Bioinformatic specialization: datamining, sequence analysis and gene regulation
dr. P. (Peter) Terpstra
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Assistant professor
Metabolic Signaling
prof. dr. K. (Kathrin) Thedieck
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Associate Professor
Protein X-ray crystallography
Structural enzymology
Structural biology
Nuclear Pore Complex, Nuclear envelope
cellular ageing; Baker's yeast replicative ageing
dr. L.M. (Liesbeth) Veenhoff
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Associate professor
Cell cycle regulation and cellular responses to genotoxic stress, DNA damage and repair pathways and their relevance for cancer treatment.
prof. dr. M.A.T.M. (Marcel) van Vugt
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Professor of Molecular Oncology, Directeur Cancer Research Center Groningen
Carbohydrate chemistry
Glycobiology
M.T.C. (Marthe) Walvoort, PhD
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Assistant Professor (Rosalind Franklin fellow)
dr. P.M. Weissert
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Policy officer research
Peroxisomal Membrane Protein degradation, Ubiquitination.
dr. C.P. (Chris) Williams
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Group Leader (VIDI laureate)
prof. dr. M.D. (Martin) Witte
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Associate Professor
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Biological Chemistry
Mass spectrometry
Solid phase peptide synthesis
Peptide Chemistry

Proteomics/Mass Spectrometry/Biochemistry
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