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Publicaties 2008

Hieronder vindt u de publicaties van de basiseenheid Farmaceutische Biologie in 2008. Indien u op een titel klikt, dan wordt u (indien mogelijk) automatisch naar de publicatie doorgelinked.

 

Wassenaar,T.A.; Quax,W.J.; Mark,A.E. The conformation of the extracellular binding domain of Death Receptor 5 in the presence and absence of the activating ligand TRAIL: A molecular dynamics study . Proteins 2008;70(2):333-43.

 

Krzeslak, J., Gerritse, G., van Merkerk, R., Cool, R.H., Quax, W.J. Lipase Expression in Pseudomonas alcaligenes is under Control of a Two-Component Regulatory System. Appl Environ Microbiol. 2008;74(5):1402-1411.

 

Boersma, Y.L., Dröge, M.J., Van der Sloot, A.M., Pijning, T., Cool, R.H., Dijkstra, B.W., Quax, W.J. A novel genetic selection system for improved enantioselectivity of Bacillus subtilis lipase A. Chembiochem 2008; 9(7):1110-1115.

 

Duarte, N., Kayser, O., Abreu, P., Ferreira M.J. Antileishmanial activity of piceatannol isolated from Euphorbia lagascae seeds. Phytoter Res. 2008 Apr;22(4):455-457.

 

Julsing, M.K., Vasilev, N.P., Schneidman-Duhovny, D., Muntendam, R., Woerdenbag, H.J., Quax, W.J., Wolfson, H.J., Ionkova, I., Kayser, O. Metabolic stereoselectivity of cytochrome P450 3A4 towards deoxypodophyllotoxin: In silico predictions and experimental validation. Eur. J. Med. Chem 2008, 43(6): 1171-1179.

 

Lopez-Gallego,F., Betancor,L., Sio,C.F., Reis,C.R., Jimenez, P.N., Guisan,J.M., Quax,W.J., Fernandez-Lafuente,R. Evaluation of different glutaryl hydolysis of acylase mutants to improve the cephalosporin C in the absence of hydrogen peroxide. Advanced Synthesis & Catalysis, 350  (2): 343-348. 

 

Tur, V.,van der Sloot, A.M., Reis, C.R.. Szegezdi, E., Cool, R.H., Samali,A., Serrano,L., Quax,W.J. DR4 selective TRAIL variants obtained by structure based design J. Biol. Chem 2008 , 283( 29): 20560–20568. 

 

Tarrus,M.; van der Sloot,A.M.; Temming,K.; Lacombe,M.; Opdam,F.; Quax,W.J.; Molema,G.; Poelstra,K.; Kok,R.J. RGD-avidin-biotin pretargeting to alpha(v)beta (3) integrin enhances the proapoptotic activity of TNFalpha related apoptosis inducing ligand (TRAIL)  Apoptosis 2008 Feb;13(2):225-235.

 

Staniek, A., Woerdenbag, H.J.,Kayser, O. Endophytes: exploiting biodiversity for the improvement of natural product - based drug discovery. Journal of Plant Interactions 2008, Vol. 3, No. 2, 75-93.

 

Weiner, B., Poelarends, G.J., Janssen, D.B., and Feringa, B.L. Biocatalytic enantioselective synthesis of N-substituted aspartic acids by aspartate ammonia lyase.   Chemistry 2008; 14(32):10094-10100.

 

Poelarends, G.J., Puthan Veetil, V., and Whitman, C.P. The chemical versatility of the β-α-β fold: catalytic promiscuity and divergent evolution in the tautomerase superfamily. Cell. Mol. Life Sci. 2008; 65(22):3606-3618.

 

Poelarends, G.J. , Serrano, H., Person, M.D., Johnson, W.H., Jr., and Whitman, C.P. Characterization of Cg10062 from Corynebacterium glutamicum: implications for the evolution of cis-3-chloroacrylic acid dehalogenase activity in the tautomerase superfamily. Biochemistry 2008; 47(31):8139-8147.

 

Boersma,Y.L., Pijning,T., Bosma,M.S., van der Sloot,A.M., Godinho,L.F., Droge,M.J., Winter,R.T., van Pouderoyen,G., Dijkstra,B.W., & Quax,W.J. Loop grafting of Bacillus subtilis lipase A: Inversion of enantioselectivity. Chemistry & Biology 2008; 15(8): 782-789.

 

Westers, L., Westers, H., Zanen, G., Antelmann, H., Hecker, M., Noone, D., Devine, K.M.,van Dijl, J.M., Quax, W.J. Genetic or chemical protease inhibition causes significant changes in the Bacillus subtilis exoproteome. Proteomics, 2008; 8(13): 2704-2713.

 

Wu, B., Szymanski, W., Wietzes, P., de Wildeman, S., Poelarends, G.J., Feringa, B.L., and Janssen, D.B. (2008) Enzymatic synthesis of enantiopure α- and β-amino acids by phenylalanine aminomutase-catalyzed amination of cinnamic acid derivatives. ChemBioChem, in press.

 

Kouwen, T. R., Dubois, J. Y., Freudl, R., Quax, W. J., van Dijl, J. M. Modulation of Thiol-Disulfide Oxidoreductases for Increased Production of Disulfide-Bond-Containing Proteins in Bacillus subtilis . Appl. Environ. Microbiol. 2008; 74(24): 7536-7545.

 

Seifert, K., Lemke, A., Croft, S. L., Kayser, O. Antileishmanial structure-activity relationships of synthetic phospholipids: In vitro and in vivo activities of selected derivatives. Antimicrobial Agents and Chemotherapy 2007; 51(12): 4525-4528.

 

Patenten:

Rodrigues dos Reis, C. R., Quax, W. J., Samali, A, Szegezdi, E., Natoni, A., Cool, R. H., van der Sloot, A. M., Serrano, L., Tur, V.Improved Cytokine Design. Application number and date: WO2008IB03476, 21-11-2008.

  

Samali, A, Szegezdi E, Mahalingam D, Duiker E.W., de Vries E.G.E, de Jong, S., Rodrigues dos Reis, C. R., de Ruijter, M, Cool, R. H., Quax, W. J.Trail variants for treating cancer. Application number and date: WO2008IB03720, 17-12-2008.

  

Proefschriften:

Lemke, A. New formulation approaches for the leishmanicidal drug Miltefosine and for the polyene antibiotic Amphotericin B. 15 februari 2008. ISBN printed version: 978-90-367-3273-4

 

Westers, L. The BACELL factory and therapeutic proteins. 12 september 2008.

 

 

 

Laatst gewijzigd:04 maart 2019 16:15
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