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Boterman, M., Elzinga, C.R.S., Wagemakers, D., Eppens, P.B., Zaagsma, J., Meurs, H. Potentiation of ß-adrenoceptor function in bovine tracheal smooth muscle by inhibition of protein kinase C. Eur.J.Pharmacol., 516: 85-92.

Demuth, D.G., Gkoumassi, E., Dröge,M.J., Dekkers, B.G., Esselink, H.J., Ree van, R.M., Parsons, M.E., Zaagsma, J., Molleman, A., Nelemans, S.A. Arachidonic acid mediates non-capacitative calcium entry evoked by CB1-cannabinoid receptor activation in DDT1 MF-2 smooth muscle cells. J.Cell.Physiol., 205(1): 58-67.

Gladkevich, A., Nelemans, S.A., Kauffman, H., Korf, J., Microarray profiling of lymphocytes in internal diseases with an altered immune response, potential and methodology. Mediators Inflamm., 6: 317-330.

Gosens, R., Bos, I.S., Zaagsma, J, Meurs, H. Protective effects of tiotropium bromide in the progression of airway smooth muscle remodeling. Am.J.Respir.Crit.Care Med., 171(10): 1096-1102.

Heeswijk van, J.C.F., Vianen, G.J.; Thillart van den, G.E.E.J.M., Zaagsma, J. Beta-adrenergic control of plasma glucose and free fatty acid levels in the air-breathing African catfish Clarias gariepinus, Burchell 1822. J. Exp.Biol., 208: 2217-2225.

Heijink, I.H., Vellenga, E., Oostendorp, J., Monchy de, J.G.R., Postma, D.S., Kauffman, H.F. Exposure to TARC alters ß2-adrenergic receptor signaling in human peripheral blood T lymphocytes. Am.J.Physiol.Lung Cell Mol.Physiol., 289: L53-L59.

Lutz, S., Freichel-Blomquist, A., Yang, Y., Rümenapp, U., Jakobs, K.H., Schmidt, M., Wieland, T. The guanine nucleotide exchange factor p63RhoGEF, a specific link between Gq/11-coupled receptor signaling and RhoA. J.Biol.Chem., 280(12): 11134-11139.

Maarsingh, H., Tio, M., Zaagsma, J., Meurs, H. Arginase attenuates inhibitory nonadrenergic noncholinergic nerve-induced nitric oxide generation and airway smooth muscle relaxation. Respir.Res., 6: 23.

Oostendorp, J., Postma, D.S., Volders, H., Jongepier, H., Kauffman, H.F., Boezen, M., Meyers, D.A., Bleecker, E.R., Nelemans, S.A., Zaagsma, J., Meurs, H. Differential desensitization of homozygous haplotypes of the b2-adrenergic receptor in lymphocytes.  A.J.Respir.Crit.Care Med., 172(3): 322-328.

Ricciardolo, F.L., Zaagsma, J., Meurs, H. The therapeutic potential of drugs targeting the arginase pathway in asthma. Exp.Opin.Investig.Drugs, 14(10): 1221-1231.

Schaafsma, D., Gosens, R., Bos, I.S.T., Meurs, H., Zaagsma, J., Nelemans, S.A. Role of contractile prostaglandins and Rho-kinase in growth factor-induced airway smooth muscle contraction. Respir.Res., 6(1): 85.

Westerhof, F.J., Zuidhof, A.B., Kok, L., Meurs, H., Zaagsma, J. Effects of salbutamol and enantiomers on allergen-induced asthmatic reactions and airway hyperreactivity. Eur.Respir.J., 25(5): 864-872.

Woude van der, H., Zaagsma, J., Postma, D., Winter, T., Hulst van, M., Aalbers, R. Detrimental effects of ß-blockers in COPD: A concern for nonselective ß-blockers. Chest, 127: 818-824.

National publication:

Zaagsma, J., Aalbers, R., Molen van der, T. Combinatie therapie: meer dan de som der delen. Pharm.Weekbl., 40: 1252-1255.

Chapter in books:

Nelemans, S.A., Measurement of [CA2+]i in cell suspensions using indo-1. In: Methods in Molecular Biology, vol. 312, Calcium Signalling Protocols (second edition), David G. Lambert, eds. (Humana Press), pp 47-53.

Westerink, B.H.C. Zaagsma, J. Nicotine en het centrale zenuwstelsel. In: Tabaksgebruik; gevolgen en bestrijding, H. Knol, C. Hilvering, D.J.Th. Wagener, M.C. Willemsen, eds. (Utrecht: Lemma), pp. 70-76.

Zijlstra, F.J., Zaagsma, J. Farmacologie van nicotine. In: Tabaksgebruik: gevolgen en bestrijding, H. Knol, C. Hilvering, D.J.Th. Wagener, M.C. Willemsen, eds. (Utrecht: Lemma), pp. 65-70.


Oostendorp, J., ß-Adrenergic receptor regulation and airway inflammation. Promotores: Meurs, H., Zaagsma, J., Postma, D.S., Kauffman, H.F. Copromotor: Biber, K.P. Rijksuniversiteit Groningen, 20 april, 2005, 179 pp. ISBN 90-90193333-2.

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