Wijmenga, Prof. Cisca
Prof. Cisca Wijmenga has been Professor of Human Genetics at the University of Groningen and head of the Genetics Department of the University Medical Center Groningen since 2007. The aim of her research is to understand the role that genes play in the development of chronic diseases. Her research group focuses on the genetics of inflammation-related conditions, such as coeliac disease (gluten allergy) and inflammatory intestinal disease (e.g. Crohn’s disease, ulcerative colitis). Research led by Wijmenga has discovered several genes that are involved in causing such immune-related disorders. This knowledge is leading to new insights into the disease process, and could possibly result in new treatments for patients.
Prof. Wijmenga has been elected a member of the Royal Netherlands Academy of Arts and Sciences (KNAW) in 2012. Members of KNAW are all prominent academics from all disciplines and are chosen on the basis of nominations from within and outside the Academy. In the same year she received a prestigious ERC Advanced Grant for her research project on Celiac disease. The BBMRI-NL2.0 project, a collaboration led by Wijmenga between biobanks in the Netherlands, received EUR 9.8 million from NWO in 2014. In 2015 Wijmenga has been awarded a Spinoza Prize, also referred to as the 'Dutch Nobel Prize'.
From 2019 - 2023, Wijmenga was rector magnificus of the RUG. She was the first female rector in the 405-year history of the UG.
More video's
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'Een ontzettende erkenning voor mijn werk' (Wijmenga in Nieuwsuur, vanaf 39.00)
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Wat krijgen we mee en wat laten we na? (‘What are we given, and what do we leave behind?’)
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Kunnen we ons een fout permitteren? (‘Can we afford to make a mistake?’)
Previously in the news
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Grant for biobanks (in Dutch)
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Red wine and butter milk are good for your gut (NOS, in Dutch)
Contact and further information
Publications
2023
BBJ,
BioMe, BioVU, Canadian Partnership for Tomorrow's Health/OHS, China
Kadoorie Biobank Collaborative Group, Colorado Center for
Personalized Medicine, deCODE Genetics, ESTBB, FinnGen, Generation
Scotland, Genes & Health, LifeLines, Mass General Brigham
Biobank, Michigan Genomics Initiative, QIMR Berghofer Biobank,
Taiwan Biobank, The HUNT Study, UCLA ATLAS Community Health
Initiative, UKBB, ... Hirbo, J. B. (2023). Global Biobank
analyses provide lessons for developing polygenic risk scores
across diverse cohorts. Cell Genomics,
3(1), Article 100241. https://doi.org/10.1016/j.xgen.2022.100241
Brushett,
S., Gacesa, R., Vila, A. V.,
Gois, M. F. B., Andreu-Sánchez, S.,
Swarte, J. C., Klaassen, M. A. Y., Collij,
V., Sinha, T., Bolte, L. A., Wu,
J., Swertz, M., Kroon, M. L. A. D.,
Reijneveld, S. A., Wijmenga, C., Weersma,
R. K., Fu, J., Loo, H. M.
V., Kurilshikov, A., & Zhernakova,
A. (2023). Gut feelings: the relations between
depression, anxiety, psychotropic drugs and the gut
microbiome. Gut Microbes,
15(2), Article 2281360. https://doi.org/10.1080/19490976.2023.2281360
Palasantzas,
V. E. J. M., Tamargo-Rubio, I., Le,
K., Slager, J., Wijmenga,
C., Jonkers, I. H., Kumar,
V., Fu, J., & Withoff, S.
(2023). iPSC-derived organ-on-a-chip models for personalized
human genetics and pharmacogenomics studies.
Trends in Genetics, 39(4). https://doi.org/10.1016/j.tig.2023.01.002
eQTLGen
Consortium, Dai, Q., Zhou, G., Zhao, H., Võsa,
U., Franke, L., Battle, A., Teumer, A.,
Lehtimäki, T., Raitakari, O. T., Esko, T., Epstein, M. P.,
& Yang, J. (2023). OTTERS: a powerful TWAS framework
leveraging summary-level reference data. Nature
Communications, 14, Article 1271. https://doi.org/10.1038/s41467-023-36862-w
Bourgonje,
A. R., Andreu-Sánchez, S., Vogl, T.,
Hu, S., Vich Vila, A., Gacesa, R.,
Leviatan, S., Kurilshchikov, A., Klompus, S., Kalka,
I. N., van Dullemen, H. M., Weinberger, A.,
Visschedijk, M. C., Festen, E. A. M.,
Faber, K. N., Wijmenga, C., Dijkstra,
G., Segal, E., Fu, J., ... Weersma, R.
K. (2023). Phage-display immunoprecipitation
sequencing of the antibody epitope repertoire in inflammatory bowel
disease reveals distinct antibody signatures.
Immunity, 56(6), 1393-1409.e6. https://doi.org/10.1016/j.immuni.2023.04.017
Lifelines
Cohort Study, Andreu-Sánchez, S.,
Bourgonje, A. R., Vogl, T., Kurilshchikov, A.,
Leviatan, S., Ruiz-Moreno, A. J., Hu,
S., Sinha, T., Vich Vila, A.,
Klompus, S., Kalka, I. N., de Leeuw, K., Arends,
S., Jonkers, I., Withoff,
S., Brouwer, E., Weinberger, A.,
Wijmenga, C., ... Zhernakova, A. (2023).
Phage display sequencing reveals that genetic, environmental,
and intrinsic factors influence variation of human antibody epitope
repertoire. Immunity, 56(6),
1376-1392.e8. https://doi.org/10.1016/j.immuni.2023.04.003
The
Netherlands A. C. M./P. L. N. Registry, Lifelines Cohort
Study, Lopera-Maya, E. A., Li, S.,
de Brouwer, R., Nolte, I. M., van Breen,
J., Jongbloed, J. D. H., Swertz, M.
A., Snieder, H., Franke, L.,
Wijmenga, C., de Boer, R. A., Deelen,
P., van der Zwaag, P. A., & Sanna,
S. (Accepted/In press). Phenotypic and Genetic Factors
Associated with Absence of Cardiomyopathy Symptoms in
PLN:c.40_42delAGA Carriers. Journal of
cardiovascular translational research. https://doi.org/10.1007/s12265-022-10347-5
Lifelines
Corona Research initiative, Goërtz, Y. M. J., Spruit, M. A.,
Van Herck, M., Dukers-Muijrers, N., van der Kallen, C. J. H.,
Burtin, C., & Janssen, D. J. A. (2023). Symptoms and
quality of life before, during, and after a SARS-CoV-2 PCR positive
or negative test: data from Lifelines. Scientific
Reports, 13, Article 11713. https://doi.org/10.1038/s41598-023-38223-5
Lifelines
Corona Research initiative, Mobach, M. P., Boezen, H.
M., Mierau, J. O., Franke, H.
L., Dekens, J., Deelen, P.,
Lanting, P., Vonk, J. M., Nolte,
I., Ori, A. P. S., Claringbould,
A., Boulogne, F., Dijkema, M. X. L.,
Wiersma, H. H., Warmerdam, R.,
Jankipersadsing, S. A., van Blokland, I.,
de Bock, G. T. H., ... Wijmenga, C. (2023).
Workplace impact on employees: A Lifelines Corona Research
Initiative on the return to work. PLoS
ONE, 18(1), Article e0279902. https://doi.org/10.1371/journal.pone.0279902
2022
Chu,
X., Janssen, A. W. M., Koenen, H., Chang, L., He, X.,
Joosten, I., Stienstra, R., Kuijpers, Y., Wijmenga,
C., Xu, C-J., Netea, M. G., Tack, C. J., Li,
Y., & Buettner, C. (2022). A genome-wide
functional genomics approach uncovers genetic determinants of
immune phenotypes in type 1 diabetes.
eLife, 11, Article 73709. https://doi.org/10.7554/eLife.73709
Lifelines
Cohort Study, Lopera-Maya, E. A., Kurilshikov,
A., van der Graaf, A., Hu,
S., Andreu-Sánchez, S., Chen,
L., Vila, A. V., Gacesa, R.,
Sinha, T., Collij, V., Klaassen, M. A.
Y., Bolte, L. A., Gois, M. F. B.,
Neerincx, P. B. T., Swertz, M. A.,
Harmsen, H. J. M., Wijmenga, C., Fu,
J., ... Sanna, S. (2022). Author
Correction: Effect of host genetics on the gut microbiome in 7,738
participants of the Dutch Microbiome Project (Nature Genetics,
(2022), 54, 2, (143-151), 10.1038/s41588-021-00992-y).
Nature genetics, 54(9), 1448. https://doi.org/10.1038/s41588-022-01164-2
Gulyaeva,
A., Garmaeva, S., Ruigrok, R. A. A. A.,
Wang, D., Riksen, N. P., Netea, M. G., Wijmenga,
C., Weersma, R. K., Fu, J.,
Vila, A. V., Kurilshikov, A., &
Zhernakova, A. (2022). Discovery, diversity, and
functional associations of crAss-like phages in human gut
metagenomes from four Dutch cohorts. Cell
reports, 38(2), Article 110204. https://doi.org/10.1016/j.celrep.2021.110204
Lopera-Maya,
E. A., Kurilshikov, A., van der Graaf,
A., Hu, S., Lifelines Cohort Study,
Andreu-Sánchez, S., Chen, L., Vila,
A. V., Gacesa, R., Sinha,
T., Collij, V., Klaassen, M. A. Y.,
Bolte, L. A., Brandao Gois, M. F.,
Neerincx, P. B. T., Swertz, M. A.,
Harmsen, H. J. M., Wijmenga, C., Fu,
J., ... Sanna, S. (2022). Effect of host
genetics on the gut microbiome in 7,738 participants of the Dutch
Microbiome Project. Nature genetics,
54, 143-151. https://doi.org/10.1038/s41588-021-00992-y
Lifelines
Cohort Study, Lopera-Maya, E. A., Kurilshikov,
A., van der Graaf, A., Hu,
S., Andreu-Sánchez, S., Chen,
L., Vich-Vila, A., Gacesa,
R., Sinha, T., Collij, V.,
Klassen, M. A. Y., Bolte, L. A., Brandao-Gois,
M. F., Neerincx, P. B. T., Swertz, M.
A., Harmsen, H. J. M., Wijmenga,
C., Fu, J., ... Sanna, S. (2022).
Effect of host genetics on the gut microbiome in 7,738
participants of the Dutch Microbiome Project.
European Journal of Human Genetics,
30(SUPPL 1), 589-589.
Gacesa,
R., Kurilshikov, A., Vich Vila,
A., Sinha, T., Klaassen, M. A. Y., Bolte,
L. A., Andreu-Sánchez, S., Chen,
L., Collij, V., Hu, S.,
Dekens, J. A. M., Lenters, V. C., Björk, J.
R., Swarte, J. C., Swertz, M.
A., Jansen, B. H., Gelderloos-Arends, J.,
Jankipersadsing, S., Hofker, M., ... Weersma, R.
K. (2022). Environmental factors shaping the gut
microbiome in a Dutch population.
Nature, 732–739. https://doi.org/10.1038/s41586-022-04567-7
Andreu-Sánchez,
S., Aubert, G., Ripoll-Cladellas, A., Henkelman, S.,
Zhernakova, D. V., Sinha, T.,
Kurilshikov, A., Cenit, M. C., Jan Bonder,
M., Franke, L., Wijmenga,
C., Fu, J., van der Wijst, M. G.
P., Melé, M., Lansdorp, P., &
Zhernakova, A. (2022). Genetic, parental and lifestyle
factors influence telomere length. Communications
biology, 5(1), Article 565. https://doi.org/10.1038/s42003-022-03521-7
BIOS
Consortium, Brain MEND Consortium, Hop, P. J., Zwamborn, R. A. J.,
Hannon, E., Shireby, G. L., Nabais, M. F., Walker, E. M., van
Rheenen, W., van Vugt, J. J. F. A., Dekker, A. M., Westeneng, H.
J., Tazelaar, G. H. P., van Eijk, K. R., Moisse, M., Baird, D., Al
Khleifat, A., Iacoangeli, A., Ticozzi, N., ... Veldink, J. H.
(2022). Genome-wide study of DNA methylation shows
alterations in metabolic, inflammatory, and cholesterol pathways in
ALS. Science Translational Medicine,
14(633), Article eabj0264. https://doi.org/10.1126/scitranslmed.abj0264
deCODE
Genetics, Estonian Biobank, FinnGen, Generation Scotland, Genes
& Health Research Team, LifeLines, Mass General Brigham
Biobank, Michigan Genomics Initiative, National Biobank of Korea,
Penn Medicine BioBank, Qatar Biobank, The QSkin Sun and Health
Study, Taiwan Biobank, The HUNT Study, UCLA ATLAS Community Health
Initiative, Uganda Genome Resource, UK Biobank, Biobank of the
Americas, BioBank Japan Project, ... Sanna, S. (2022).
Global Biobank Meta-analysis Initiative: Powering genetic
discovery across human disease. Cell
Genomics, 2(10), Article 100192. https://doi.org/10.1016/j.xgen.2022.100192
Swarte,
J. C., Li, Y., Hu, S.,
Björk, J. R., Gacesa, R., Vich Vila,
A., Douwes, R. M., Collij,
V., Kurilshikov, A., Post, A.,
Klaassen, M. A. Y., Eisenga, M. F., Gomes-Neto,
A. W., Kremer, D., Jansen, B.
H., Knobbe, T. J., Berger, S.
P., Sanders, J-S. F., Heiner-Fokkema, M.
R., ... Weersma, R. K. (2022). Gut
microbiome dysbiosis is associated with increased mortality after
solid organ transplantation. Science Translational
Medicine, 14(660), Article eabn7566. https://doi.org/10.1126/scitranslmed.abn7566
Bourgonje,
A. R., Andreu-Sánchez, S., Vogl, T.,
Hu, S., Vich Vila, A., Leviatan, S.,
Kurilshchikov, A., Klompus, S., Kalka, I. N., van
Dullemen, H. M., Weinberger, A., Visschedijk, M.
C., Festen, E. A. M., Faber, K.
N., Wijmenga, C., Dijkstra, G.,
Segal, E., Fu, J., Zhernakova, A.,
& Weersma, R. K. (2022). In-depth characterisation
of the serum antibody epitope repertoire in Inflammatory Bowel
Disease by high-throughput phage-displayed immunoprecipitation
sequencing. Journal of Crohn's and
Colitis, 16(Suppl(1)), S100-S102. https://doi.org/10.1093/ecco-jcc/jjab232.092
Lifelines
Cohort Study, Chen, L., Zhernakova, D.
V., Kurilshikov, A., Andreu-Sánchez,
S., Wang, D., Augustijn, H. E., Vich
Vila, A., Weersma, R. K., Medema, M. H., Netea,
M. G., Kuipers, F., Wijmenga, C.,
Zhernakova, A., & Fu, J. (2022).
Influence of the microbiome, diet and genetics on
inter-individual variation in the human plasma metabolome.
Nature Medicine, 28,
2333–2343. https://doi.org/10.1038/s41591-022-02014-8
Mujagic,
Z., Kasapi, M., Jonkers, D. M. A. E., Garcia-Perez, I., Vork, L.,
Weerts, Z. Z. R. M., Serrano-Contreras, J. I., Zhernakova,
A., Kurilshikov, A., Scotcher, J., Holmes,
E., Wijmenga, C., Keszthelyi, D., Nicholson, J. K.,
Posma, J. M., & Masclee, A. A. M. (2022). Integrated
fecal microbiome–metabolome signatures reflect stress and
serotonin metabolism in irritable bowel syndrome.
Gut Microbes, 14(1), Article
2063016. https://doi.org/10.1080/19490976.2022.2063016
Global
Biobank Meta-analysis Initiative, Kanai, M., Elzur, R., Zhou, W.,
Daly, M. J., & Finucane, H. K. (2022). Meta-analysis
fine-mapping is often miscalibrated at single-variant
resolution. Cell Genomics,
2(12), Article 100210. https://doi.org/10.1016/j.xgen.2022.100210
Estonian
Biobank Research Team, Lepamets, M., Auwerx, C., Nõukas,
M., Claringbould, A., Porcu, E., Kals, M.,
Jürgenson, T., Morris, A. P., Võsa, U.,
Bochud, M., Stringhini, S., Wijmenga, C.,
Franke, L., Peterson, H., Vilo, J., Lepik, K., Mägi,
R., & Kutalik, Z. (2022). Omics-informed CNV calls reduce
false-positive rates and improve power for CNV-trait
associations. Human Genetics and Genomics
Advances, 3(4), Article 100133. https://doi.org/10.1016/j.xhgg.2022.100133
Ramírez-Sánchez,
A. D., Chu, X., Modderman, R., Kooy-Winkelaar,
Y., Koletzko, S., Korponay-Szabó, I. R., Troncone, R.,
Wijmenga, C., Mearin, L., Withoff, S.,
Jonkers, I. H., & Li, Y. (2022). Single-Cell RNA
Sequencing of Peripheral Blood Mononuclear Cells From Pediatric
Coeliac Disease Patients Suggests Potential Pre-Seroconversion
Markers. Frontiers in Immunology,
13, Article 843086. https://doi.org/10.3389/fimmu.2022.843086
Doestzada,
M., Zhernakova, D. V., C L van den Munckhof,
I., Wang, D., Kurilshikov, A.,
Chen, L., Bloks, V. W., van Faassen,
M., Rutten, J. H. W., Joosten, L. A. B., Netea, M. G.,
Wijmenga, C., Riksen, N. P., Zhernakova,
A., Kuipers, F., & Fu, J.
(2022). Systematic analysis of relationships between plasma
branched-chain amino acid concentrations and cardiometabolic
parameters: an association and Mendelian randomization
study. BMC Medicine, 20(1),
Article 485. https://doi.org/10.1186/s12916-022-02688-4
TANDEM
Consortium, van Doorn, C. L. R., Eckold, C., Ronacher, K., Ruslami,
R., van Veen, S., Lee, J-S., Kumar, V., Kerry-Barnard,
S., Malherbe, S. T., Kleynhans, L., Stanley, K., Hill, P. C.,
Joosten, S. A., van Crevel, R., Wijmenga, C.,
Critchley, J. A., Walzl, G., Alisjahbana, B., ... Cliff, J. M.
(2022). Transcriptional profiles predict treatment outcome in
patients with tuberculosis and diabetes at diagnosis and at two
weeks after initiation of anti-tuberculosis treatment.
EBioMedicine, 82, Article 104173. https://doi.org/10.1016/j.ebiom.2022.104173
2021
Moorlag,
S. J. C. F. M., Matzaraki, V., van Puffelen Heijden,
J. H., van der Heijden, C., Keating, S., Groh, L., Bakker, O.
B., Koeken, V. A. C. M., de Bree, L. C. J., Smeekens, S. P.,
Oosting, M., Gamboa, R. A., Riksen, N. P., Xavier, R.
J., Wijmenga, C., Kumar, V., van Crevel,
R., Novakovic, B., Joosten, L. A. B., ... Netea, M. G. (2022).
An integrative genomics approach identifies KDM4 as a
modulator of trained immunity. European Journal of
Immunology, 52(3), 431-446. https://doi.org/10.1002/eji.202149577
Brandao
Gois, M. F., Sinha, T., Spreckels, J.
E., Vich Vila, A., Bolte, L.
A., Weersma, R. K., Wijmenga,
C., Fu, J., Zhernakova, A.,
& Kurilshikov, A. (2022). Role of the gut
microbiome in mediating lactose intolerance symptoms.
Gut, 71(1), 215-217. https://doi.org/10.1136/gutjnl-2020-323911
Gacesa,
R., Vich Vila, A., Collij, V.,
Mujagic, Z., Kurilshikov, A., Voskuil, M.
D., Festen, E. A. M., Wijmenga,
C., Jonkers, D. M. A. E., Dijkstra, G.,
Fu, J., Zhernakova, A., Imhann,
F., & Weersma, R. K. (2021). A
combination of fecal calprotectin and human beta-defensin 2
facilitates diagnosis and monitoring of inflammatory bowel
disease. Gut Microbes, 13(1),
Article 1943288. https://doi.org/10.1080/19490976.2021.1943288
Tan,
I. L., Barisani, D., Panceri, R., Modderman, R.,
Visschedijk, M., Weersma, R. K.,
Wijmenga, C., Jonkers, I., Coutinho de Almeida,
R., & Withoff, S. (2021). A Combined mRNA-
and miRNA-Sequencing Approach Reveals miRNAs as Potential
Regulators of the Small Intestinal Transcriptome in Celiac
Disease. International Journal of Molecular
Sciences, 22(21), Article 11382. https://doi.org/10.3390/ijms222111382
Wang,
D., Doestzada, M., Chen, L.,
Andreu-Sánchez, S., van den Munckhof, I. C. L.,
Augustijn, H. E., Koehorst, M., Ruiz-Moreno, A.
J., Bloks, V. W., Riksen, N. P., Rutten, J. H.
W., Joosten, L. A. B., Netea, M. G., Wijmenga,
C., Zhernakova, A., Kuipers,
F., & Fu, J. (2021). Characterization
of gut microbial structural variations as determinants of human
bile acid metabolism. Cell Host &
Microbe, 29(12), 1802-1814.e5. https://doi.org/10.1016/j.chom.2021.11.003
Tan,
I. L., Coutinho de Almeida, R., Modderman, R., Stachurska,
A., Dekens, J., Barisani, D., Meijer, C. R., Roca, M.,
Martinez-Ojinaga, E., Shamir, R., Auricchio, R.,
Korponay-Szabó, I. R., Castillejo, G., Szajewska, H.,
Koletzko, S., Zhernakova, A., Kumar,
V., Li, Y., Visschedijk, M.
C., ... Withoff, S. (2021). Circulating
miRNAs as Potential Biomarkers for Celiac Disease
Development. Frontiers in Immunology,
12, Article 734763. https://doi.org/10.3389/fimmu.2021.734763
Gulyaeva,
A., Garmaeva, S., Ruigrok, R. A. A. A.,
Wang, D., Riksen, N. P., Netea, M. G., Wijmenga,
C., Weersma, R. K., Fu, J.,
Vila, A. V., Kurilshikov, A., &
Zhernakova, A. (2021). Discovery, diversity and
functional associations of crAss-like phages in human gut
metagenomes from four Dutch cohorts. BioRxiv. https://doi.org/10.1101/2021.06.01.446427
Wijmenga,
C. (2021). From LD-based mapping to GWAS.
Nature Reviews Genetics, 22(8). https://doi.org/10.1038/s41576-021-00366-4
Ortiz
Fernández, L., Coit, P., Yilmaz, V., Yentür, S. P.,
Alibaz-Oner, F., Aksu, K., Erken, E., Düzgün, N., Keser,
G., Cefle, A., Yazici, A., Ergen, A., Alpsoy, E., Salvarani, C.,
Casali, B., Kısacık, B., Kötter, I., Henes, J.,
Çınar, M., ... Sawalha, A. H. (2021). Genetic
Association of a Gain-of-Function IFNGR1 Polymorphism and the
Intergenic Region LNCAROD/DKK1 With Behcet's Disease.
Arthritis & Rheumatology, 73(7),
1244-1252. https://doi.org/10.1002/art.41637
Peters,
V., Tigchelaar-Feenstra, E. F., Imhann,
F., Dekens, J. A. M., Swertz, M.
A., Franke, L. H., Wijmenga,
C., Weersma, R. K., Alizadeh, B.
Z., Dijkstra, G., &
Campmans-Kuijpers, M. J. E. (2021). Habitual dietary
intake of IBD patients differs from population controls: A
case-control study. European Journal of
Nutrition, 60, 345–356. https://doi.org/10.1007/s00394-020-02250-z
Brand,
E. C., Klaassen, M. A. Y., Gacesa, R., Vila, A.
V., Ghosh, H., de Zoete, M. R., Boomsma, D. I.,
Hoentjen, F., Horjus Talabur Horje, C. S., van de Meeberg, P. C.,
Willemsen, G., Fu, J., Wijmenga, C., van
Wijk, F., Zhernakova, A., Oldenburg, B.,
Weersma, R. K., & Dutch TWIN-IBD consortium and the
Dutch Initiative on Crohn and Colitis (2021). Healthy Cotwins
Share Gut Microbiome Signatures With Their Inflammatory Bowel
Disease Twins and Unrelated Patients.
Gastroenterology, 160(6), 1970-1985.
https://doi.org/10.1053/j.gastro.2021.01.030
Matzaraki,
V., Le, K. T. T., Jaeger, M.,
Aguirre-Gamboa, R., Johnson, M. D., Sanna, S.,
Rosati, D., Franke, L., Zhernakova,
A., Fu, J., Withoff, S.,
Jonkers, I., Li, Y., Joosten, L. A. B., Netea,
M. G., Wijmenga, C., & Kumar, V.
(2021). Inflammatory Protein Profiles in Plasma of
Candidaemia Patients and the Contribution of Host Genetics to Their
Variability. Frontiers in Immunology,
12, Article 662171. https://doi.org/10.3389/fimmu.2021.662171
Chu,
X., Jaeger, M., Beumer, J., Bakker, O.
B., Aguirre-Gamboa, R., Oosting, M., Smeekens,
S. P., Moorlag, S., Mourits, V. P., Koeken, V. A. C. M., de Bree,
C., Jansen, T., Mathews, I. T., Dao, K., Najhawan, M., Watrous, J.
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