Wijmenga, Prof. Cisca
Prof. Cisca Wijmenga has been Professor of Human Genetics at the University of Groningen and head of the Genetics Department of the University Medical Center Groningen since 2007. The aim of her research is to understand the role that genes play in the development of chronic diseases. Her research group focuses on the genetics of inflammation-related conditions, such as coeliac disease (gluten allergy) and inflammatory intestinal disease (e.g. Crohn’s disease, ulcerative colitis). Research led by Wijmenga has discovered several genes that are involved in causing such immune-related disorders. This knowledge is leading to new insights into the disease process, and could possibly result in new treatments for patients.
Prof. Wijmenga has been elected a member of the Royal Netherlands Academy of Arts and Sciences (KNAW) in 2012. Members of KNAW are all prominent academics from all disciplines and are chosen on the basis of nominations from within and outside the Academy. In the same year she received a prestigious ERC Advanced Grant for her research project on Celiac disease. The BBMRI-NL2.0 project, a collaboration led by Wijmenga between biobanks in the Netherlands, received EUR 9.8 million from NWO in 2014. In 2015 Wijmenga has been awarded a Spinoza Prize, also referred to as the 'Dutch Nobel Prize'.
From 2019 - 2023, Wijmenga was rector magnificus of the RUG. She was the first female rector in the 405-year history of the UG.
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Contact and further information
Publications
2024
Simpson,
H. L., Smits, E., Moerkens,
R., Wijmenga, C., Mooiweer,
J., Jonkers, I. H., & Withoff,
S. (2025). Human organoids and organ-on-chips in
coeliac disease research. Trends in Molecular
Medicine, 31(2), 117-137. https://doi.org/10.1016/j.molmed.2024.10.003
Moerkens,
R., Mooiweer, J.,
Ramírez-Sánchez, A. D., Oelen,
R., Franke, L., Wijmenga, C.,
Barrett, R. J., Jonkers, I. H., & Withoff,
S. (2024). An iPSC-derived small intestine-on-chip
with self-organizing epithelial, mesenchymal, and neural
cells. Cell reports, 43(7),
Article 114247. https://doi.org/10.1016/j.celrep.2024.114247
Lifelines
Corona Research initiative, Goërtz, Y. M. J., Spruit, M. A.,
Van Herck, M., Dukers-Muijrers, N., van der Kallen, C. J. H.,
Burtin, C., & Janssen, D. J. A. (2024). Author
Correction: Symptoms and quality of life before, during, and after
a SARS-CoV-2 PCR positive or negative test: data from Lifelines
(Scientific Reports, (2023), 13, 1, (11713),
10.1038/s41598-023-38223-5). Scientific
Reports, 14, Article 8390. https://doi.org/10.1038/s41598-024-58848-4
Fernández-Pato,
A., Sinha, T., Gacesa, R.,
Andreu-Sánchez, S., Gois, M. F. B.,
Gelderloos-Arends, J., Jansen, D. B. H.,
Kruk, M., Jaeger, M., Joosten, L. A. B., Netea, M. G.,
Weersma, R. K., Wijmenga, C., Harmsen, H.
J. M., Fu, J., Zhernakova,
A., & Kurilshikov, A. (2024). Choice
of DNA extraction method affects stool microbiome recovery and
subsequent phenotypic association analyses.
Scientific Reports, 14, Article
3911. https://doi.org/10.1038/s41598-024-54353-w
International
Multiple Sclerosis Genetics Consortium, Lincoln, M. R., Connally,
N., Axisa, P.-P., Gasperi, C., Mitrovic, M., van Heel, D.,
Wijmenga, C., Withoff, S., Jonkers, I.
H., Padyukov, L., Rich, S. S., Graham, R. R., Gaffney, P.
M., Langefeld, C. D., Vyse, T. J., Hafler, D. A., Chun, S.,
Sunyaev, S. R., & Cotsapas, C. (2024). Genetic mapping
across autoimmune diseases reveals shared associations and
mechanisms. Nature genetics,
56(5), 838-845. https://doi.org/10.1038/s41588-024-01732-8
Slager,
J., Simpson, H. L., Gacesa,
R., Chen, L., Tan, I. L.,
Gelderloos, J., Maatman, A., Wijmenga,
C., Zhernakova, A., Fu, J.,
Weersma, R. K., Gonera, G., Jonkers, I.
H., & Withoff, S. (2024).
High-resolution analysis of the treated coeliac disease
microbiome reveals strain-level variation. BioRxiv. https://doi.org/10.1101/2024.03.08.584098
Lifelines
Cohort Study, Zhernakova, D. V., Wang,
D., Liu, L., Andreu-Sánchez,
S., Zhang, Y., Ruiz-Moreno, A.
J., Peng, H., Plomp, N., Del
Castillo-Izquierdo, Á., Gacesa, R.,
Lopera-Maya, E. A., Temba, G. S., Kullaya, V. I., van
Leeuwen, S. S., Xavier, R. J., de Mast, Q., Joosten, L. A.
B., Riksen, N. P., ... Fu, J. (2024). Host
genetic regulation of human gut microbial structural
variation. Nature, 625,
813–821. https://doi.org/10.1038/s41586-023-06893-w
Moerkens,
R., Mooiweer, J., Smits, E.,
Berg, M., Ramírez-Sánchez, A.
D., Modderman, R., Puschhof, J.,
Pleguezuelos-Manzano, C., Barrett, R. J., Wijmenga,
C., Jonkers, I. H., & Withoff,
S. (2024). Intestine-on-chip enhances nutrient and
drug metabolism and maturation of iPSC-derived intestinal
epithelial cells relative to organoids and Transwells.
BioRxiv. https://doi.org/10.1101/2024.06.30.601390
Demirkan,
A., van Dongen, J., Finnicum, C. T., Westra, H.
J., Jankipersadsing, S., Willemsen, G.,
Ijzerman, R. G., Boomsma, D. I., Ehli, E. A., Bonder, M.
J., Fu, J., Franke, L.,
Wijmenga, C., de Geus, E. J. C., Kurilshikov,
A., & Zhernakova, A. (2024). Linking
the gut microbiome to host DNA methylation by a discovery and
replication epigenome-wide association study. BMC
Genomics, 25, Article 1224. https://doi.org/10.1186/s12864-024-11136-x
BBMRI
Consortium, Bizzarri, D., Reinders, M. J. T., Kuiper, L., Beekman,
M., Deelen, J., van Meurs, J. B. J., van Dongen, J., Pool, R.,
Boomsma, D. I., Ghanbari, M., & Franke, L. (2024).
NMR metabolomics-guided DNA methylation mortality
predictors. EBioMedicine,
107, Article 105279. https://doi.org/10.1016/j.ebiom.2024.105279
Bios
Consortium , van Hilten, A., van Rooij, J., Ikram, M. A.,
Niessen, W. J., van Meurs, J. B. J., & Roshchupkin, G.
V. (2024). Phenotype prediction using biologically
interpretable neural networks on multi-cohort multi-omics
data. npj Systems Biology and
Applications, 10, Article 81. https://doi.org/10.1038/s41540-024-00405-w
Tan,
I. L., Modderman, R., Stachurska, A., Almeida,
R., de Vries, R., Heersema, D. J.,
Gacesa, R., Wijmenga, C., Jonkers, I.
H., Meilof, J. F., & Withoff, S. (2024).
Potential biomarkers for multiple sclerosis stage from
targeted proteomics and microRNA sequencing. Brain
Communications, 6(4), Article fcae209. https://doi.org/10.1093/braincomms/fcae209
Lifelines
NEXT cohort study, Garmaeva, S., Sinha,
T., Gulyaeva, A., Kuzub, N.,
Spreckels, J. E., Andreu-Sánchez,
S., Gacesa, R., Vich Vila,
A., Brushett, S., Kruk, M.,
Dekens, J., Sikkema, J., Kuipers,
F., Shkoporov, A. N., Hill, C., Scherjon,
S., Wijmenga, C., Fu, J.,
... Zhernakova, A. (2024). Transmission and dynamics
of mother-infant gut viruses during pregnancy and early
life. Nature Communications,
15(1), Article 1945. https://doi.org/10.1038/s41467-024-45257-4
2023
BBJ,
BioMe, BioVU, Canadian Partnership for Tomorrow's Health/OHS, China
Kadoorie Biobank Collaborative Group, Colorado Center for
Personalized Medicine, deCODE Genetics, ESTBB, FinnGen, Generation
Scotland, Genes & Health, LifeLines, Mass General Brigham
Biobank, Michigan Genomics Initiative, QIMR Berghofer Biobank,
Taiwan Biobank, The HUNT Study, UCLA ATLAS Community Health
Initiative, UKBB, ... Hirbo, J. B. (2023). Global Biobank
analyses provide lessons for developing polygenic risk scores
across diverse cohorts. Cell Genomics,
3(1), Article 100241. https://doi.org/10.1016/j.xgen.2022.100241
Brushett,
S., Gacesa, R., Vila, A. V.,
Gois, M. F. B., Andreu-Sánchez, S.,
Swarte, J. C., Klaassen, M. A. Y.,
Collij, V., Sinha, T., Bolte, L.
A., Wu, J., Swertz, M., Kroon, M. L. A.
D., Reijneveld, S. A., Wijmenga,
C., Weersma, R. K., Fu, J.,
Loo, H. M. V., Kurilshikov, A., &
Zhernakova, A. (2023). Gut feelings: the relations
between depression, anxiety, psychotropic drugs and the gut
microbiome. Gut Microbes,
15(2), Article 2281360. https://doi.org/10.1080/19490976.2023.2281360
Hamburg
Intestinal Tissue Study Group, International Inflammatory Bowel
Disease Genetics Consortium, Baumdick, M. E., Niehrs, A.,
Degenhardt, F., Schwerk, M., Hinrichs, O., Jordan-Paiz, A., Padoan,
B., Wegner, L. H. M., Schloer, S., Zecher, B. F., Malsy, J., Joshi,
V. R., Illig, C., Schröder-Schwarz, J., Möller, K. J.,
Martin, M. P., Yuki, Y., ... Franke, A. (2023). HLA-DP on
Epithelial Cells Enables Tissue Damage by NKp44+ Natural
Killer Cells in Ulcerative Colitis.
Gastroenterology, 165(4),
946-962.e13. https://doi.org/10.1053/j.gastro.2023.06.034
Gois,
M. F. B., Fernández-Pato, A., Huss,
A., Gacesa, R., Wijmenga, C.,
Weersma, R. K., Fu, J., Vermeulen, R. C.
H., Zhernakova, A., Lenters, V. C., &
Kurilshikov, A. (2023). Impact of occupational
pesticide exposure on the human gut microbiome.
Frontiers in Microbiology, 14,
Article 1223120. https://doi.org/10.3389/fmicb.2023.1223120
TANDEM
Consortium$, Eckold, C., van Doorn, C. L. R., Ruslami, R.,
Ronacher, K., Riza, A.-L., van Veen, S., Lee,
J.-S., Kumar, V., Kerry-Barnard, S., Malherbe, S. T.,
Kleynhans, L., Stanley, K., Joosten, S. A., Critchley, J. A., Hill,
P. C., van Crevel, R., Wijmenga, C., Haks, M. C., ...
Cliff, J. M. (2023). Impaired resolution of blood
transcriptomes through tuberculosis treatment with diabetes
comorbidity. Clinical and Translational
Medicine, 13(9), Article e1375. https://doi.org/10.1002/ctm2.1375
Palasantzas,
V. E. J. M., Tamargo-Rubio, I., Le,
K., Slager, J., Wijmenga,
C., Jonkers, I. H., Kumar,
V., Fu, J., & Withoff, S.
(2023). iPSC-derived organ-on-a-chip models for personalized
human genetics and pharmacogenomics studies.
Trends in Genetics, 39(4), 268-284.
https://doi.org/10.1016/j.tig.2023.01.002
Wijmenga,
C. (2023, Apr 5). Ons microbioom: een afspiegeling van
ons dagelijks leven. https://www.darmgezondheid.nl/columns-ciska-wijmenga-microbioom/
eQTLgen
Consortium, Dai, Q., Zhou, G., Zhao, H., Võsa,
U., Franke, L., Battle, A., Teumer, A.,
Lehtimäki, T., Raitakari, O. T., Esko, T., Epstein, M. P.,
& Yang, J. (2023). OTTERS: a powerful TWAS framework
leveraging summary-level reference data. Nature
Communications, 14, Article 1271. https://doi.org/10.1038/s41467-023-36862-w
Bourgonje,
A. R., Andreu-Sánchez, S., Vogl, T.,
Hu, S., Vich Vila, A., Gacesa, R.,
Leviatan, S., Kurilshchikov, A., Klompus, S., Kalka,
I. N., van Dullemen, H. M., Weinberger, A.,
Visschedijk, M. C., Festen, E. A. M.,
Faber, K. N., Wijmenga, C., Dijkstra,
G., Segal, E., Fu, J., ... Weersma, R.
K. (2023). Phage-display immunoprecipitation
sequencing of the antibody epitope repertoire in inflammatory bowel
disease reveals distinct antibody signatures.
Immunity, 56(6), 1393-1409.e6. https://doi.org/10.1016/j.immuni.2023.04.017
Lifelines
Cohort Study, Andreu-Sánchez, S.,
Bourgonje, A. R., Vogl, T., Kurilshchikov, A.,
Leviatan, S., Ruiz-Moreno, A. J., Hu,
S., Sinha, T., Vich Vila, A.,
Klompus, S., Kalka, I. N., de Leeuw, K., Arends,
S., Jonkers, I., Withoff,
S., Brouwer, E., Weinberger, A.,
Wijmenga, C., ... Zhernakova, A. (2023).
Phage display sequencing reveals that genetic, environmental,
and intrinsic factors influence variation of human antibody epitope
repertoire. Immunity, 56(6),
1376-1392.e8. https://doi.org/10.1016/j.immuni.2023.04.003
The
Netherlands A. C. M./P. L. N. Registry, Lifelines Cohort
Study, Lopera-Maya, E. A., Li, S.,
de Brouwer, R., Nolte, I. M., van Breen,
J., Jongbloed, J. D. H., Swertz, M.
A., Snieder, H., Franke, L.,
Wijmenga, C., de Boer, R. A., Deelen,
P., van der Zwaag, P. A., & Sanna,
S. (2023). Phenotypic and Genetic Factors Associated
with Absence of Cardiomyopathy Symptoms in PLN:c.40_42delAGA
Carriers. Journal of cardiovascular translational
research, 16, 1251–1266. https://doi.org/10.1007/s12265-022-10347-5
Lifelines
Corona Research initiative, Goërtz, Y. M. J., Spruit, M. A.,
Van Herck, M., Dukers-Muijrers, N., van der Kallen, C. J. H.,
Burtin, C., & Janssen, D. J. A. (2023). Symptoms and
quality of life before, during, and after a SARS-CoV-2 PCR positive
or negative test: data from Lifelines. Scientific
Reports, 13, Article 11713. https://doi.org/10.1038/s41598-023-38223-5
Lifelines
Corona Research initiative, Mobach, M. P., Boezen, H.
M., Mierau, J. O., Franke, H.
L., Dekens, J., Deelen, P.,
Lanting, P., Vonk, J. M., Nolte,
I., Ori, A. P. S., Claringbould,
A., Boulogne, F., Dijkema, M. X. L.,
Wiersma, H. H., Warmerdam, R.,
Jankipersadsing, S. A., van Blokland, I.,
de Bock, G. T. H., ... Wijmenga, C. (2023).
Workplace impact on employees: A Lifelines Corona Research
Initiative on the return to work. PLoS
ONE, 18(1), Article e0279902. https://doi.org/10.1371/journal.pone.0279902
2022
Chu,
X., Janssen, A. W. M., Koenen, H., Chang, L., He, X.,
Joosten, I., Stienstra, R., Kuijpers, Y., Wijmenga,
C., Xu, C.-J., Netea, M. G., Tack, C. J., Li,
Y., & Buettner, C. (2022). A genome-wide
functional genomics approach uncovers genetic determinants of
immune phenotypes in type 1 diabetes.
eLife, 11, Article 73709. https://doi.org/10.7554/eLife.73709
Lifelines
Cohort Study, Lopera-Maya, E. A., Kurilshikov,
A., van der Graaf, A., Hu,
S., Andreu-Sánchez, S., Chen,
L., Vila, A. V., Gacesa, R.,
Sinha, T., Collij, V., Klaassen, M. A.
Y., Bolte, L. A., Gois, M. F.
B., Neerincx, P. B. T., Swertz, M.
A., Harmsen, H. J. M., Wijmenga,
C., Fu, J., ... Sanna, S. (2022).
Author Correction: Effect of host genetics on the gut
microbiome in 7,738 participants of the Dutch Microbiome Project
(Nature Genetics, (2022), 54, 2, (143-151),
10.1038/s41588-021-00992-y). Nature
genetics, 54(9), 1448. https://doi.org/10.1038/s41588-022-01164-2
Gulyaeva,
A., Garmaeva, S., Ruigrok, R. A. A.
A., Wang, D., Riksen, N. P., Netea, M.
G., Wijmenga, C., Weersma, R. K.,
Fu, J., Vila, A. V., Kurilshikov,
A., & Zhernakova, A. (2022).
Discovery, diversity, and functional associations of
crAss-like phages in human gut metagenomes from four Dutch
cohorts. Cell reports, 38(2),
Article 110204. https://doi.org/10.1016/j.celrep.2021.110204
Lopera-Maya,
E. A., Kurilshikov, A., van der Graaf,
A., Hu, S., Lifelines Cohort Study,
Andreu-Sánchez, S., Chen, L., Vila,
A. V., Gacesa, R., Sinha,
T., Collij, V., Klaassen, M. A.
Y., Bolte, L. A., Brandao Gois, M.
F., Neerincx, P. B. T., Swertz, M.
A., Harmsen, H. J. M., Wijmenga,
C., Fu, J., ... Sanna, S. (2022).
Effect of host genetics on the gut microbiome in 7,738
participants of the Dutch Microbiome Project.
Nature genetics, 54, 143-151. https://doi.org/10.1038/s41588-021-00992-y
Lifelines
Cohort Study, Lopera-Maya, E. A., Kurilshikov,
A., van der Graaf, A., Hu,
S., Andreu-Sánchez, S., Chen,
L., Vich-Vila, A., Gacesa,
R., Sinha, T., Collij, V.,
Klassen, M. A. Y., Bolte, L. A., Brandao-Gois,
M. F., Neerincx, P. B. T., Swertz, M.
A., Harmsen, H. J. M., Wijmenga,
C., Fu, J., ... Sanna, S. (2022).
Effect of host genetics on the gut microbiome in 7,738
participants of the Dutch Microbiome Project.
European Journal of Human Genetics,
30(SUPPL 1), 589-589.
Gacesa,
R., Kurilshikov, A., Vich Vila,
A., Sinha, T., Klaassen, M. A.
Y., Bolte, L. A., Andreu-Sánchez,
S., Chen, L., Collij, V.,
Hu, S., Dekens, J. A. M., Lenters, V. C.,
Björk, J. R., Swarte, J. C., Swertz,
M. A., Jansen, B. H., Gelderloos-Arends,
J., Jankipersadsing, S., Hofker, M., ...
Weersma, R. K. (2022). Environmental factors shaping
the gut microbiome in a Dutch population.
Nature, 732–739. https://doi.org/10.1038/s41586-022-04567-7
Andreu-Sánchez,
S., Aubert, G., Ripoll-Cladellas, A., Henkelman, S.,
Zhernakova, D. V., Sinha, T.,
Kurilshikov, A., Cenit, M. C., Jan Bonder,
M., Franke, L., Wijmenga,
C., Fu, J., van der Wijst, M. G.
P., Melé, M., Lansdorp, P., &
Zhernakova, A. (2022). Genetic, parental and lifestyle
factors influence telomere length. Communications
biology, 5(1), Article 565. https://doi.org/10.1038/s42003-022-03521-7
BIOS
Consortium, Brain MEND Consortium, Hop, P. J., Zwamborn, R. A. J.,
Hannon, E., Shireby, G. L., Nabais, M. F., Walker, E. M., van
Rheenen, W., van Vugt, J. J. F. A., Dekker, A. M., Westeneng, H.
J., Tazelaar, G. H. P., van Eijk, K. R., Moisse, M., Baird, D., Al
Khleifat, A., Iacoangeli, A., Ticozzi, N., ... Veldink, J. H.
(2022). Genome-wide study of DNA methylation shows
alterations in metabolic, inflammatory, and cholesterol pathways in
ALS. Science Translational Medicine,
14(633), Article eabj0264. https://doi.org/10.1126/scitranslmed.abj0264
deCODE
Genetics, Estonian Biobank, FinnGen, Generation Scotland, Genes
& Health Research Team, LifeLines, Mass General Brigham
Biobank, Michigan Genomics Initiative, National Biobank of Korea,
Penn Medicine BioBank, Qatar Biobank, The QSkin Sun and Health
Study, Taiwan Biobank, The HUNT Study, UCLA ATLAS Community Health
Initiative, Uganda Genome Resource, UK Biobank, Biobank of the
Americas, BioBank Japan Project, ... Sanna, S. (2022).
Global Biobank Meta-analysis Initiative: Powering genetic
discovery across human disease. Cell
Genomics, 2(10), Article 100192. https://doi.org/10.1016/j.xgen.2022.100192
Swarte,
J. C., Li, Y., Hu, S.,
Björk, J. R., Gacesa, R., Vich Vila,
A., Douwes, R. M., Collij,
V., Kurilshikov, A., Post,
A., Klaassen, M. A. Y., Eisenga, M.
F., Gomes-Neto, A. W., Kremer,
D., Jansen, B. H., Knobbe, T.
J., Berger, S. P., Sanders, J.-S.
F., Heiner-Fokkema, M. R., ... Weersma,
R. K. (2022). Gut microbiome dysbiosis is associated
with increased mortality after solid organ transplantation.
Science Translational Medicine,
14(660), Article eabn7566. https://doi.org/10.1126/scitranslmed.abn7566
Bourgonje,
A. R., Andreu-Sánchez, S., Vogl, T.,
Hu, S., Vich Vila, A., Leviatan, S.,
Kurilshchikov, A., Klompus, S., Kalka, I. N., van
Dullemen, H. M., Weinberger, A., Visschedijk, M.
C., Festen, E. A. M., Faber, K.
N., Wijmenga, C., Dijkstra, G.,
Segal, E., Fu, J., Zhernakova, A.,
& Weersma, R. K. (2022). In-depth characterisation
of the serum antibody epitope repertoire in Inflammatory Bowel
Disease by high-throughput phage-displayed immunoprecipitation
sequencing. Journal of Crohn's and
Colitis, 16(Suppl(1)), S100-S102. https://doi.org/10.1093/ecco-jcc/jjab232.092
Lifelines
Cohort Study, Chen, L., Zhernakova, D.
V., Kurilshikov, A., Andreu-Sánchez,
S., Wang, D., Augustijn, H. E., Vich
Vila, A., Weersma, R. K., Medema, M. H., Netea,
M. G., Kuipers, F., Wijmenga, C.,
Zhernakova, A., & Fu, J. (2022).
Influence of the microbiome, diet and genetics on
inter-individual variation in the human plasma metabolome.
Nature Medicine, 28,
2333–2343. https://doi.org/10.1038/s41591-022-02014-8
Mujagic,
Z., Kasapi, M., Jonkers, D. M. A. E., Garcia-Perez, I., Vork, L.,
Weerts, Z. Z. R. M., Serrano-Contreras, J. I., Zhernakova,
A., Kurilshikov, A., Scotcher, J., Holmes,
E., Wijmenga, C., Keszthelyi, D., Nicholson, J. K.,
Posma, J. M., & Masclee, A. A. M. (2022). Integrated
fecal microbiome–metabolome signatures reflect stress and
serotonin metabolism in irritable bowel syndrome.
Gut Microbes, 14(1), Article
2063016. https://doi.org/10.1080/19490976.2022.2063016
Global
Biobank Meta-analysis Initiative, Kanai, M., Elzur, R., Zhou, W.,
Daly, M. J., & Finucane, H. K. (2022). Meta-analysis
fine-mapping is often miscalibrated at single-variant
resolution. Cell Genomics,
2(12), Article 100210. https://doi.org/10.1016/j.xgen.2022.100210
Estonian
Biobank Research Team, Lepamets, M., Auwerx, C., Nõukas,
M., Claringbould, A., Porcu, E., Kals, M.,
Jürgenson, T., Morris, A. P., Võsa, U.,
Bochud, M., Stringhini, S., Wijmenga, C.,
Franke, L., Peterson, H., Vilo, J., Lepik, K., Mägi,
R., & Kutalik, Z. (2022). Omics-informed CNV calls reduce
false-positive rates and improve power for CNV-trait
associations. Human Genetics and Genomics
Advances, 3(4), Article 100133. https://doi.org/10.1016/j.xhgg.2022.100133
Ramírez-Sánchez,
A. D., Chu, X., Modderman, R.,
Kooy-Winkelaar, Y., Koletzko, S., Korponay-Szabó, I. R.,
Troncone, R., Wijmenga, C., Mearin, L., Withoff,
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