prof. dr. C. (Cisca) Wijmenga

Rector

prof. dr. C. (Cisca) Wijmenga
Telephone:
Secretariat: Greet Vlaskamp and Monique Peperkamp (cvb.rm@rug.nl):
E-mail:
c.wijmenga rug.nl

Research

  1. 2019
  2. Clark, D. W., Okada, Y., Moore, K. H. S., Mason, D., Pirastu, N., Gandin, I., ... Wilson, J. F. (2019). Associations of autozygosity with a broad range of human phenotypes. Nature Communications, 10(1), [4957]. https://doi.org/10.1038/s41467-019-12283-6
  3. BIOS Consortium, van Dongen, J., Zilhao, N. R., Sugden, K., Hannon, E. J., Mill, J., ... Boomsma, D. (2019). Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults. Biological Psychiatry, 86(8), 599-607. https://doi.org/10.1016/j.biopsych.2019.02.016
  4. Consortium for the study of genetic associations of celiac disease in Latin-America, Ricaño-Ponce, I., Gutierrez-Achury, J., Costa, A. F., Deelen, P., Kurilshikov, A., ... Wijmenga, C. (2019). Immunochip meta-analysis in European and Argentinian populations identifies two novel genetic loci associated with celiac disease. EJHG. https://doi.org/10.1038/s41431-019-0520-4
  5. Edwards, R. A., Vega, A. A., Norman, H. M., Ohaeri, M., Levi, K., Dinsdale, E. A., ... Wijmenga, C. (2019). Global phylogeography and ancient evolution of the widespread human gut virus crAssphage. Nature Microbiology, 4(10), 1727-1736. https://doi.org/10.1038/s41564-019-0494-6
  6. Johansson, L. F., van Dijk-Bos, K. K., van der Hout, A. H., Knopperts, A. P., Leegte, B., ter Beest, J., ... Westers, H. (2019). What if we would turn a diagnostic multi-cancer gene panel into a screening tool? European Journal of Human Genetics, 27, 1126-1126.
  7. Jaeger, M., Pinelli, M., Borghi, M., Constantini, C., Dindo, M., van Emst, L., ... Netea, M. G. (2019). A systems genomics approach identifies SIGLEC15 as a susceptibility factor in recurrent vulvovaginal candidiasis. Science Translational Medicine, 11(496), [3558]. https://doi.org/10.1126/scitranslmed.aar3558
  8. Zeevi, D., Korem, T., Godneva, A., Bar, N., Kurilshikov, A., Lotan-Pompan, M., ... Segal, E. (2019). Structural variation in the gut microbiome associates with host health. Nature, 568(7750), 43-48. https://doi.org/10.1038/s41586-019-1065-y
  9. Valles-Colomer, M., Falony, G., Darzi, Y., Tigchelaar, E. F., Wang, J., Tito, R. Y., ... Raes, J. (2019). The neuroactive potential of the human gut microbiota in quality of life and depression. Nature Microbiology, 4(4), 623-632. https://doi.org/10.1038/s41564-018-0337-x
  10. Myositis Genetics Consortium, Scleroderma Genetics Consortium, Acosta-Herrera, M., Kerick, M., Gonzalez-Serna, D., Wijmenga, C., ... Martin, J. (2019). Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases. Annals of the Rheumatic Diseases, 78(3), 311-319. https://doi.org/10.1136/annrheumdis-2018-214127
  11. Mayassi, T., Ladell, K., Gudjonson, H., McLaren, J. E., Shaw, D. G., Tran, M. T., ... Jabri, B. (2019). Chronic Inflammation Permanently Reshapes Tissue-Resident Immunity in Celiac Disease. Cell, 176(5), 967-981,e19. https://doi.org/10.1016/j.cell.2018.12.039
  12. Franzosa, E. A., Sirota-Madi, A., Avila-Pacheco, J., Fornelos, N., Haiser, H. J., Reinker, S., ... Xavier, R. J. (2019). Gut microbiome structure and metabolic activity in inflammatory bowel disease. Nature Microbiology, 4(2), 293-305. https://doi.org/10.1038/s41564-018-0306-4
  13. Domínguez-Andrés, J., Novakovic, B., Li, Y., Scicluna, B. P., Gresnigt, M. S., Arts, R. J. W., ... Netea, M. G. (2019). The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity. Cell metabolism, 29(1), 211-220.e5. https://doi.org/10.1016/j.cmet.2018.09.003
  14. 2018
  15. Coeliac Dis Immunochip Consortium, Rheumatoid Arthrit Consortium Int, Int Scleroderma Grp, & Type 1 Diabet Genetics Consortium (2018). Meta-analysis of Immunochip data of four autoimmune diseases reveals novel single-disease and cross-phenotype associations. Genome medicine, 10, [97]. https://doi.org/10.1186/s13073-018-0604-8
  16. Tunjungputri, R. N., Li, Y., de Groot, P. G., Dinarello, C. A., Smeekens, S. P., Jaeger, M., ... de Mast, Q. (2018). The Inter-Relationship of Platelets with Interleukin-1 beta-Mediated Inflammation in Humans. Thrombosis and Haemostasis, 118(12), 2112-2125. https://doi.org/10.1055/s-0038-1675603
  17. BIOS Consortium, Luijk, R., Wu, H., Ward-Caviness, C. K., Hannon, E., Carnero-Montoro, E., ... Heijmans, B. T. (2018). Autosomal genetic variation is associated with DNA methylation in regions variably escaping X-chromosome inactivation. Nature Communications, 9(1), 3738. [3738]. https://doi.org/10.1038/s41467-018-05714-3
  18. BIOS Consortium, Luijk, R., Dekkers, K. F., van Iterson, M., Arindrarto, W., Claringbould, A., ... van Zwet, E. W. (2018). Genome-wide identification of directed gene networks using large-scale population genomics data. Nature Communications, 9(1), 3097. [3097]. https://doi.org/10.1038/s41467-018-05452-6
  19. Lifelines-DEEP Cohort Study, & BBMRI Metabolomics Consortium (2018). Microbial impact on plasma metabolites is linked to the cardiovascular risk and phenotypes. Atherosclerosis supplements, 32, 118-119.
  20. Xu, C-J., Söderhäll, C., Bustamante, M., Baïz, N., Gruzieva, O., Gehring, U., ... BIOS Consortium (2018). DNA methylation in childhood asthma: an epigenome-wide meta-analysis. The Lancet. Respiratory Medicine, 6(5), 379-388. https://doi.org/10.1016/S2213-2600(18)30052-3
  21. Ghanbari, M., Peters, M. J., de Vries, P. S., Boer, C. G., van Rooij, J. G. J., Lee, Y-C., ... Dehghan, A. (2018). A systematic analysis highlights multiple long non-coding RNAs associated with cardiometabolic disorders. Journal of human genetics, 63(4), 431-446. https://doi.org/10.1038/s10038-017-0403-x
  22. Rothschild, D., Weissbrod, O., Barkan, E., Kurilshikov, A., Korem, T., Zeevi, D., ... Segal, E. (2018). Environment dominates over host genetics in shaping human gut microbiota. Nature, 555(7695), 210-228. https://doi.org/10.1038/nature25973
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