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Poolman, Prof. Bert

Bert Poolman
Bert Poolman
Bert Poolman was trained in bioenergetics and microbiology and moved to biochemistry and biophysics in later years. Central questions in his research are: How do molecules permeate biological membranes and how can one control solute fluxes? Throughout his career, he has made seminal contributions to the understanding of the dynamics and permeability of biological membranes and to the field of vectorial biochemistry, i.e. the role of electrochemical gradients in the fuelling and regulation of membrane transport. Poolman has a leading record in the energetics of membrane transport and cellular osmoregulation as well as the development of innovative technologies in membrane reconstitution. He has advanced the field of ATP-binding cassette (ABC) transporters, one of the largest known protein families, by combining functional and structural studies.

Bert Poolman is scientific director of the Groningen Biomolecular Sciences and Biotechnology Institute, and he is program director of the Centre for Synthetic Biology. He has published over 270 articles in international peer-refereed scientific journals and supervised about 50 PhD students. He is ISI highly-cited researcher and member of the Faculty 1000 board. Poolman has been a member of the Royal Dutch Academy of Arts and Sciences (KNAW) since 2009.

In April 2015 Poolman was awarded a European ERC Advanced Grant of 2,5 million euros for his project 'ABCVolume: The ABC of Cell Volume Regulation'.

Previously in the news

Article for De Groene Amsterdammer
Article for De Groene Amsterdammer

2020

Pols, T., Singh, S., Deelman-Driessen, C., Gaastra, B. F., & Poolman, B. (2020). Enzymology of the pathway for ATP production by arginine breakdown. The FEBS Journal, [febs.15337]. https://doi.org/10.1111/febs.15337
Liu, B., Mavrova, S. N., van den Berg, J., Kristensen, S. K., Mantovanelli, L., Veenhoff, L. M., Poolman, B., & Boersma, A. J. (2020). Erratum. ACS Sensors, 5(5), 1500-1500. https://doi.org/10.1021/acssensors.0c00744
Van't Klooster, J. S., Bianchi, F., Doorn, R. B., Lorenzon, M., Lusseveld, J. H., Punter, C. M., & Poolman, B. (2020). Extracellular loops matter: Subcellular location and function of the lysine transporter Lyp1 from Saccharomyces cerevisiae. The FEBS Journal, 287(20), 4401-4414. [febs.15262]. https://doi.org/10.1111/febs.15262
Sikkema, H. R., van den Noort, M., Rheinberger, J., de Boer, M., Krepel, S. T., Schuurman-Wolters, G. K., Paulino, C., & Poolman, B. (2020). Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA. Science Advances, 6(47), [eabd7697]. https://doi.org/10.1126/sciadv.abd7697
de Boer, M., Cordes, T., & Poolman, B. (2020). Kinetic Modelling of Transport Inhibition by Substrates in ABC Importers. Journal of Molecular Biology, 432(20), 5565-5576. https://doi.org/10.1016/j.jmb.2020.08.008
van 't Klooster, J. S., Cheng, T-Y., Sikkema, H. R., Jeucken, A., Moody, D. B., & Poolman, B. (2020). Membrane Lipid Requirements of the Lysine Transporter Lyp1 from Saccharomyces cerevisiae. Journal of Molecular Biology, 432(14), 4023-4031. https://doi.org/10.1016/j.jmb.2020.04.029
van 't Klooster, J. S., Cheng, T-Y., Sikkema, H. R., Jeucken, A., Moody, B., & Poolman, B. (2020). Periprotein lipidomes of Saccharomyces cerevisiae provide a flexible environment for conformational changes of membrane proteins. eLife, 9, [e57003]. https://doi.org/10.7554/eLife.57003
Marinus, N., Tahiri, N., Duca, M., Mouthaan, L. M. C. M., Bianca, S., van den Noort, M., Poolman, B., Witte, M. D., & Minnaard, A. J. (2020). Stereoselective Protection-Free Modification of 3-Keto-saccharides. Organic letters, 22(14), 5622-5626. https://doi.org/10.1021/acs.orglett.0c01986
Thomas, C., Aller, S. G., Beis, K., Carpenter, E. P., Chang, G., Chen, L., Dassa, E., Dean, M., Duong Van Hoa, F., Ekiert, D., Ford, R., Gaudet, R., Gong, X., Holland, I. B., Huang, Y., Kahne, D. K., Kato, H., Koronakis, V., Koth, C. M., ... Tampé, R. (2020). Structural and functional diversity calls for a new classification of ABC transporters. FEBS Letters, [1873-3468.13935]. https://doi.org/10.1002/1873-3468.13935

2019

Syga, L., De Vries, R. H., van Oosterhout, H., Bartelds, R., Boersma, A. J., Roelfes, G., & Poolman, B. (2020). A trifunctional linker for palmitoylation and peptide and protein localization in biological membranes. ChemBioChem, 21(9), 1320-1328. https://doi.org/10.1002/cbic.201900655
Rempel, I. L., Popken, P., Ghavami, A., Mishra, A., Hapsari, R. A., Wolters, A. H. G., Veldsink, A. C., Klaassens, M., Meinema, A. C., Poolman, B., Giepmans, B. N. G., Onck, P. R., Steen, A., & Veenhoff, L. M. (2020). Flexible and Extended Linker Domains Support Efficient Targeting of Heh2 to the Inner Nuclear Membrane. Structure, 28(2), 185-195.e5. https://doi.org/10.1016/j.str.2019.11.003
Gabba, M., & Poolman, B. (2020). Physiochemical Modeling of Vesicle Dynamics upon Osmotic Upshift. Biophysical Journal, 118(2), 435-447. [bpj.2019.11.3383]. https://doi.org/10.1016/j.bpj.2019.11.3383
Gabba, M., Frallicciardi, J., van 't Klooster, J., Henderson, R., Syga, Ł., Mans, R., van Maris, A. J. A., & Poolman, B. (2020). Weak Acid Permeation in Synthetic Lipid Vesicles and Across the Yeast Plasma Membrane. Biophysical Journal, 118(2), 422-434. https://doi.org/10.1016/j.bpj.2019.11.3384
Pols, T., Sikkema, H. R., Gaastra, B. F., Frallicciardi, J., Śmigiel, W. M., Singh, S., & Poolman, B. (2019). A synthetic metabolic network for physicochemical homeostasis. Nature Communications, 10(1), [4239]. https://doi.org/10.1038/s41467-019-12287-2
Price, C. E., Branco Dos Santos, F., Hesseling, A., Uusitalo, J. J., Bachmann, H., Benavente, V., Goel, A., Berkhout, J., Bruggeman, F. J., Marrink, S-J., Montalban-Lopez, M., de Jong, A., Kok, J., Molenaar, D., Poolman, B., Teusink, B., & Kuipers, O. P. (2019). Adaption to glucose limitation is modulated by the pleotropic regulator CcpA, independent of selection pressure strength. BMC Evolutionary Biology, 19(1), [15]. https://doi.org/10.1186/s12862-018-1331-x
Sikkema, H. R., Gaastra, B. F., Pols, T., & Poolman, B. (2019). Cell fueling and metabolic energy conservation in synthetic cells. ChemBioChem, 20(20 SI), 2581 –2592. https://doi.org/10.1002/cbic.201900398
de Boer, M., Gkouridis, G., Vietrov, R., Begg, S. L., Schuurman-Wolters, G. K., Husada, F., Eleftheriadis, N., Poolman, B., McDevitt, C. A., & Cordes, T. (2019). Conformational and dynamical plasticity in substrate-binding proteins underlies selective transport in ABC importers. eLife, 8, [e44652]. https://doi.org/10.7554/eLife.44652
Liu, B., Hasrat, Z., Poolman, B., & Boersma, A. J. (2019). Decreased Effective Macromolecular Crowding in Escherichia coli Adapted to Hyperosmotic Stress. Journal of Bacteriology, 201(10), [e00708-18]. https://doi.org/10.1128/JB.00708-18
Smigiel, W. M., Lefrancois, P., & Poolman, B. (2019). Physicochemical considerations for bottom-up synthetic biology. Emerging topics in life sciences, 3(5), 445-458. [ETLS20190017]. https://doi.org/10.1042/ETLS20190017
Bianchi, F., Van't Klooster, J. S., Ruiz, S. J., & Poolman, B. (2019). Regulation of Amino Acid Transport in Saccharomyces cerevisiae. Microbiology and Molecular Biology Reviews, 83(4), [e00024-19]. https://doi.org/10.1128/MMBR.00024-19

2018

Henderson, R. K., Fendler, K., & Poolman, B. (2019). Coupling efficiency of secondary active transporters. Current Opinion in Biotechnology, 58, 62-71. https://doi.org/10.1016/j.copbio.2018.11.005
Marques, W. L., Mans, R., Henderson, R. K., Marella, E. R., Horst, J. T., Hulster, E. D., Poolman, B., Daran, J-M., Pronk, J. T., Gombert, A. K., & van Maris, A. J. A. (2018). Combined engineering of disaccharide transport and phosphorolysis for enhanced ATP yield from sucrose fermentation in Saccharomyces cerevisiae. Metabolic Engineering, 45, 121-133. https://doi.org/10.1016/j.ymben.2017.11.012
Lycklama A Nijeholt, J. A., Vietrov, R., Schuurman-Wolters, G. K., & Poolman, B. (2018). Energy coupling efficiency in the Type I ABC transporter GlnPQ. Journal of Molecular Biology, 430(6), 853-866. https://doi.org/10.1016/j.jmb.2018.02.001
Schavemaker, P. E., Boersma, A. J., & Poolman, B. (2018). How Important Is Protein Diffusion in Prokaryotes? Frontiers in Molecular Biosciences, 5, [fmolb.2018.00093]. https://doi.org/10.3389/fmolb.2018.00093
Schavemaker, P. E., & Poolman, B. (2018). (Membrane) Protein Production in Context. Trends in Biochemical Sciences, 43(11), 858-868. https://doi.org/10.1016/j.tibs.2018.08.009
Syga, Ł., Spakman, D., Punter, C. M., & Poolman, B. (2018). Method for immobilization of living and synthetic cells for high-resolution imaging and single-particle tracking. Scientific Reports, 8(1), [13789]. https://doi.org/10.1038/s41598-018-32166-y
Bartelds, R., Nematollahi, M. H., Pols, T., Stuart, M. C. A., Pardakhty, A., Asadikaram, G., & Poolman, B. (2018). Niosomes, an alternative for liposomal delivery. PLoS ONE, 13(4), [e0194179]. https://doi.org/10.1371/journal.pone.0194179
Schuurman-Wolters, G. K., de Boer, M., Pietrzyk, M. K., & Poolman, B. (2018). Protein linkers provide limits on the domain interactions in the ABC importer GlnPQ and determine the rate of transport. Journal of Molecular Biology, 1249-1262. [j.jmb.2018.02.014]. https://doi.org/10.1016/j.jmb.2018.02.014
Bianchi, F., Syga, Ł., Moiset, G., Spakman, D., Schavemaker, P. E., Punter, C. M., Seinen, A-B., van Oijen, A. M., Robinson, A., & Poolman, B. (2018). Steric exclusion and protein conformation determine the localization of plasma membrane transporters. Nature Communications, 9(1), [501]. https://doi.org/10.1038/s41467-018-02864-2
Liu, B., Mavrova, S. N., van den Berg, J., Kristensen, S. K., Mantovanelli, L., Veenhoff, L. M., Poolman, B., & Boersma, A. J. (2018). The influence of fluorescent protein maturation on FRET measurements in living cells. ACS Sensors, 3(9), 1735-1742. https://doi.org/10.1021/acssensors.8b00473

2017

Cozzoli, L., Gjonaj, L., Stuart, M. C. A., Poolman, B., & Roelfes, G. (2018). Responsive DNA G-quadruplex micelles. Chemical communications (Cambridge, England), 54, 260-263. https://doi.org/10.1039/c7cc07899d
Franken, L., Oostergetel, G., Pijning, T., Puri, P., Arkhipova, V. I., Boekema, E., Poolman, B., & Guskov, A. (2017). A general mechanism of ribosome dimerization revealed by single-particle cryo-electron microscopy. Nature Communications, 8, [722]. https://doi.org/10.1038/s41467-017-00718-x
Liu, B., Åberg, C., van Eerden, F. J., Marrink, S., Poolman, B., & Boersma, A. J. (2017). Design and Properties of Genetically Encoded Probes for Sensing Macromolecular Crowding. Biophysical Journal, 112(9), 1929-1939. https://doi.org/10.1016/j.bpj.2017.04.004
Liu, B., Poolman, B., & Boersma, A. J. (2017). Ionic strength sensing in living cells. ACS chemical biology, 12(10), 2510-2514. [acschembio.7b00348]. https://doi.org/10.1021/acschembio.7b00348
Bartelds, R., Barnoud, J., J. Boersma, A., J. Marrink, S., & Poolman, B. (2017). Lipid phase separation in the presence of hydrocarbons in giant unilamellar vesicles. AIMS Biophysics, 4(4), 528-542. https://doi.org/10.3934/biophy.2017.4.528
van den Berg, J., Boersma, A. J., & Poolman, B. (2017). Microorganisms maintain crowding homeostasis. Nature Reviews Microbiology, 15, 309-318. [nrmicro.2017.17]. https://doi.org/10.1038/nrmicro.2017.17
Henderson, R., & Poolman, B. (2017). Proton-solute coupling mechanism of the maltose transporter from Saccharomyces cerevisiae. Scientific Reports, 7(1), 1-12. [14375]. https://doi.org/10.1038/s41598-017-14438-1
Van Meervelt, V., Soskine, M., Singh, S., Schuurman-Wolters, G., Wijma, H. J., Poolman, B., & Maglia, G. (2017). Real-time conformational changes and controlled orientation of native proteins inside a protein nanoreactor. Journal of the American Chemical Society, 139(51), 18640-18646. [jacs.7b10106]. https://doi.org/10.1021/jacs.7b10106
Schavemaker, P. E., Śmigiel, W. M., & Poolman, B. (2017). Ribosome surface properties may impose limits on the nature of the cytoplasmic proteome. eLife, 6, [eLife.30084]. https://doi.org/10.7554/eLife.30084
Poolman, B., & Noireaux, V. (2017). Synthetic Biology: From engineering living systems to the bottom=up construction of synthetic cells. In J. van Doorn, J. Luirink, J. van der Oost, B. Oudega, L. Robertson, H. Smit, P. Willemsen, & C. Biemans (Eds.), MIGHTY MICROBES: THE AMAZING WORLD OF MICROORGANISMS (1 ed., Vol. 1, pp. 215-217). Microcanon Foundation.

2016

Popov-Čeleketić, D., Bianchi, F., Ruiz, S. J., Meutiawati, F., & Poolman, B. (2016). A Plasma Membrane Association Module in Yeast Amino Acid Transporters. The Journal of Biological Chemistry, 291(31), 16024-16037. https://doi.org/10.1074/jbc.M115.706770
Scheepers, G. H., Lycklama A Nijeholt, J. A., & Poolman, B. (2016). An updated structural classification of substrate-binding proteins. FEBS Letters, 590(23), 4393-4401. https://doi.org/10.1002/1873-3468.12445
Bianchi, F., Klooster, J. S. V. ., Ruiz, S. J., Luck, K., Pols, T., Urbatsch, I. L., & Poolman, B. (2016). Asymmetry in inward- and outward-affinity constant of transport explain unidirectional lysine flux in Saccharomyces cerevisiae. Scientific Reports, 6, 1-13. [31443]. https://doi.org/10.1038/srep31443
van den Berg, J., & Poolman, B. (2016). Compartmental Volume Regulation of E. Coli under Various Growth Conditions. Biophysical Journal, 110(3), 35A-35A. https://doi.org/10.1016/j.bpj.2015.11.259
Ruiz, S. J., Schuurman-Wolters, G. K., & Poolman, B. (2016). Crystal Structure of the Substrate-Binding Domain from Listeria monocytogenes Bile-Resistance Determinant BilE. Liquid Crystals, 6(12), 1-16. [cryst6120162]. https://doi.org/10.3390/cryst6120162
Maglia, G., Soskine, M., Biesemans, A., Meervelt, V., & Poolman, B. (2016). Nanopores with internal protein adaptors. (Patent No. WO2016166232). https://worldwide.espacenet.com/publicationDetails/originalDocument?CC=WO&NR=2016166232A1&KC=A1&FT=D&ND=3&date=20161020&DB=&locale=en_EP
van den Berg, J., Galbiati, H., Rasmussen, A., Miller, S., & Poolman, B. (2016). On the mobility, membrane location and functionality of mechanosensitive channels in Escherichia coli. Scientific Reports, 6, [32709 ]. https://doi.org/10.1038/srep32709
van Gijtenbeek, L. A., Robinson, A., van Oijen , A., Poolman, B., & Kok, J. (2016). On the Spatial Organization of mRNA, Plasmids, and Ribosomes in a Bacterial Host Overexpressing Membrane Proteins. PLoS genetics, 12(12), 1-28. [e1006523]. https://doi.org/10.1371/journal.pgen.1006523
Boersma, A., Liu, B., Åberg, C., & Poolman, B. (2016). Quantification of Macromolecular Crowding in Living Cells. Biophysical Journal, 110(3), 368A-368A. https://doi.org/10.1016/j.bpj.2015.11.1984

2015

Fulyani, F., Schuurman-Wolters, G., Slotboom, D-J., & Poolman, B. (2016). Relative rates of amino acid import via the ABC transporter GlnPQ determine the growth performance of Lactococcus lactis. Journal of Bacteriology, 198(3), 477-485. [JB.00685-15]. https://doi.org/10.1128/JB.00685-15
Boersma, A. J., Zuhorn, I. S., & Poolman, B. (2015). A sensor for quantification of macromolecular crowding in living cells. Nature Methods, 12(3), 227-229. https://doi.org/10.1038/nmeth.3257
Swier, L. J. Y. M., Slotboom, D., & Poolman, B. (2015). ABC transporters: A structure-function perspective. In A. M. George (Ed.), ABC Transporters - 40 Years on (1 ed., Vol. 1, pp. 3-36). Springer Verlag.
Laba, J. K., Steen, A., Popken, P., Chernova, A., Poolman, B., & Veenhoff, L. M. (2015). Active Nuclear Import of Membrane Proteins Revisited. Cells, 4(4), 653-673. https://doi.org/10.3390/cells4040653
Gouridis, G., Schuurman-Wolters, G., Ploetz, E., Husada, F., Vietrov, R., de Boer, M., Cordes, T., & Poolman, B. (2015). Conformational dynamics in substrate-binding domains influences transport in the ABC importer GlnPQ. Nature Structural & Molecular Biology, 22(1), 57-64. https://doi.org/10.1038/nsmb.2929
Spitzer, J., Pielak, G. J., & Poolman, B. (2015). Emergence of life: Physical chemistry changes the paradigm. Biology Direct, 10(33). https://doi.org/10.1186/s13062-015-0060-y
Ho, F. Y., & Poolman, B. (2015). Engineering Escherichia coli for Functional Expression of Membrane Proteins. Methods in Enzymology, 556, 3-21. https://doi.org/10.1016/bs.mie.2015.01.003
Driessen, A. J. M., & Poolman, B. (2015). In memoriam: Wilhelmus Nicolaas Konings (1937-2014). Extremophiles, 19, 233-234. https://doi.org/10.1007/s00792-015-0736-3
Kralt, A., Carretta, M., Mari, M., Reggiori, F., Steen, A., Poolman, B., & Veenhoff, L. M. (2015). Intrinsically disordered linker and plasma membrane-binding motif sort ist2 and ssy1 to junctions. Traffic, 16(2), 135-147. https://doi.org/10.1111/tra.12243
Goel, A., Eckhardt, T. H., Puri, P., de Jong, A., Branco dos Santos, F., Giera, M., Fusetti, F., de Vos, W. M., Kok, J., Poolman, B., Molenaar, D., Kuipers, O. P., & Teusink, B. (2015). Protein costs do not explain evolution of metabolic strategies and regulation of ribosomal content: does protein investment explain an anaerobic bacterial Crabtree effect? Molecular Microbiology, 97(1), 77-92. https://doi.org/10.1111/mmi.13012
Zollmann, T., Moiset Coll, G., Tumulka, F., Tampé, R., Poolman, B., & Abele, R. (2015). Single liposome analysis of peptide translocation by the ABC transporter TAPL. Proceedings of the National Academy of Sciences of the United States of America, 112(7), 2046-2051. https://doi.org/10.1073/pnas.1418100112
Popken, P., Ghavami, A., Onck, P. R., Poolman, B., & Veenhoff, L. M. (2015). Size-dependent leak of soluble and membrane proteins through the yeast nuclear pore complex. Molecular Biology of the Cell, 26(7), 1386-1394. https://doi.org/10.1091/mbc.E14-07-1175
Husada, F., Gouridis, G., Vietrov, R., Schuurman-Wolters, G. K., Ploetz, E., de Boer, M., Poolman, B., & Cordes, T. (2015). Watching conformational dynamics of ABC transporters with single-molecule tools. Biochemical Society Transactions, 43(5), 1041-1047. https://doi.org/10.1042/BST20150140

2014

Velasquez Guzman, J., Schuurman-Wolters, G., Birkner, J. P., Abee, T., & Poolman, B. (2014). Bacillus subtilis spore protein SpoVAC functions as a mechanosensitive channel. Molecular Microbiology. https://doi.org/10.1111/mmi.12591
Moiset, G., López, C. A., Bartelds, R., Syga, L., Rijpkema, E., Cukkemane, A., Baldus, M., Poolman, B., & Marrink, S. J. (2014). Disaccharides Impact the Lateral Organization of Lipid Membranes. Journal of the American Chemical Society, 136(46), 16167-16175. https://doi.org/10.1021/ja505476c
Gul, N., Linares, D. M., Ho, F. Y., & Poolman, B. (2014). Evolved Escherichia coli Strains for Amplified, Functional Expression of Membrane Proteins. Journal of Molecular Biology, 426(1), 136-149. https://doi.org/10.1016/j.jmb.2013.09.009
Mika, J., Schavemaker, P., Krasnikov, V., & Poolman, B. (2014). Impact of osmotic stress on protein diffusion in Lactococcus lactis. Molecular Microbiology, 94(4), 857-870. https://doi.org/10.1111/mmi.12800
Poolman, B., Martinez Linares, D., & Gul, N. (2014). Improved means and methods for expressing recombinant proteins. (Patent No. EP2796556). https://nl.espacenet.com/publicationDetails/originalDocument?CC=EP&NR=2796556A1&KC=A1&FT=D&ND=3&date=20141029&DB=&locale=nl_NL
Puri, P., Eckhardt, T. H., Franken, L. E., Fusetti, F., Stuart, M. C. A., Boekema, E. J., Kuipers, O. P., Kok, J., & Poolman, B. (2014). Lactococcus lactis YfiA is necessary and sufficient for ribosome dimerization. Molecular Microbiology, 91(2), 394-407. https://doi.org/10.1111/mmi.12468
Driessen, A., Kaback, H. R., Poolman, B., & Walker, J. E. (2014). Obituary: Wilhelmus Nicolaas Konings (1937-2014). Biochemist e-volution, 36(6), 42-43.
Puri, P., Goel, A., Bochynska, A., & Poolman, B. (2014). Regulation of acetate kinase isozymes and its importance for mixed-acid fermentation in Lactococcus lactis. Journal of Bacteriology, 196(7), 1386-1393. https://doi.org/10.1128/JB.01277-13
Franciosi, L., Postma, D. S., van den Berge, M., Govorukhina, N., Horvatovich, P. L., Fusetti, F., Poolman, B., Lodewijk, M. E., Timens, W., Bischoff, R., & ten Hacken, N. (2014). Susceptibility to COPD: Differential Proteomic Profiling after Acute Smoking. PLoS ONE, 9(7), [e102037]. https://doi.org/10.1371/journal.pone.0102037
Puri, P., Wetzel, C., Saffert, P., Gaston, K. W., Russel, S. P., Cordero Varela, J. A., van der Vlies, P., Zhang, G., Limbach, P. A., Ignatova, Z., & Poolman, B. (2014). Systematic identification of tRNAome and its dynamics in Lactococcus lactis. Molecular Microbiology, 93(5), 944-956. https://doi.org/10.1111/mmi.12710
Jansma, M., Aalbers, F. S., & Poolman, B. (2014). Van lezen naar schrijven. In W. Hoekstra, T. van Maris, B. Poolman, J. Pronk, & R. Buiter (Eds.), Synthetische Biologie: Creatief met Cellen (cahier 4 ed., Vol. 33, pp. 7-19). (Cahier Biowetenschappen en Maatschappij). Drukkerij Tesink, Zutphen. http://tijdschrift.biomaatschappij.nl

2013

Moiset, G., Cirac, A. D., Stuart, M. C. A., Marrink, S-J., Sengupta, D., & Poolman, B. (2013). Dual action of BPC194: a membrane active peptide killing bacterial cells. PLoS ONE, 8(4), [e61541]. https://doi.org/10.1371/journal.pone.0061541
Fulyani, F., Schuurman-Wolters, G. K., Vujicic - Zagar, A., Guskov, A., Slotboom, D-J., & Poolman, B. (2013). Functional Diversity of Tandem Substrate-Binding Domains in ABC Transporters from Pathogenic Bacteria. Structure, 21(10), 1879-1888. https://doi.org/10.1016/j.str.2013.07.020
Gul, N., & Poolman, B. (2013). Functional reconstitution and osmoregulatory properties of the ProU ABC transporter from Escherichia coli. Molecular Membrane Biology, 30(2), 138-148. https://doi.org/10.3109/09687688.2012.754060
Spitzer, J., & Poolman, B. (2013). How crowded is the prokaryotic cytoplasm? FEBS Letters, 587(14), 2094-2098. https://doi.org/10.1016/j.febslet.2013.05.051
Remus, D. M., Bongers, R. S., Meijerink, M., Fusetti, F., Poolman, B., de Vos, P., Wells, J. M., Kleerebezem, M., & Bron, P. A. (2013). Impact of Lactobacillus plantarum Sortase on Target Protein Sorting, Gastrointestinal Persistence, and Host Immune Response Modulation. Journal of Bacteriology, 195(3), 502-509. https://doi.org/10.1128/JB.01321-12
Poolman, B., Linares, D. M., & Gul, N. (2013). Increased production of membrane proteins. (Patent No. P100103EP00).
van den Bogaart, G., Meinema, A. C., Krasnikov, V., Veenhoff, L. M., & Poolman, B. (2013). Nuclear transport factor directs localization of protein synthesis during mitosis (Corrigendum; vol 11, pg 350, 2009). Nature Cell Biology, 15(4), 441. https://doi.org/10.1038/ncb2728
Mika, J. T., Birkner, J. P., Poolman, B., & Kocer, A. (2013). On the role of individual subunits in MscL gating: "All for one, one for all?". The FASEB Journal, 27(3), 882-892. https://doi.org/10.1096/fj.12-214361
Karasawa, A., Swier, L. J. Y. M., Stuart, M. C. A., Brouwers, J., Helms, B., & Poolman, B. (2013). Physicochemical factors controlling the activity and energy coupling of an ionic strength-gated ATP-binding cassette (ABC) transporter. J. Biol. Chem., 288(41), 29862-29871. https://doi.org/10.1074/jbc.M113.499327
Franciosi, L., Govorukhina, N., Fusetti, F., Poolman, B., Lodewijk, M. E., Timens, W., Postma, D., ten Hacken, N., & Bischoff, R. (2013). Proteomic analysis of human epithelial lining fluid by microfluidics-based nanoLC-MS/MS: A feasibility study. Electrophoresis, 34(18), 2683-2694. https://doi.org/10.1002/elps.201300020
Meinema, A. C., Poolman, B., & Veenhoff, L. M. (2013). Quantitative Analysis of Membrane Protein Transport Across the Nuclear Pore Complex. Traffic, 14(5), 487-501. https://doi.org/10.1111/tra.12048
Poolman, B., & Slotboom, D-J. (2013). Substrate Capture by ABC Transporters. In G. C. K. Roberts (Ed.), Encyclopedia of Biophysics (pp. 2503-2509). Springer.

2012

Gandhi, T., Puri, P., Fusetti, F., Breitling, R., Poolman, B., & Permentier, H. P. (2012). Effect of iTRAQ Labeling on the Relative Abundance of Peptide Fragment Ions Produced by MALDI-MS/MS. Journal of Proteome Research, 11(8), 4044-4051. https://doi.org/10.1021/pr300083x
Gul, N., Schuurman-Wolters, G., Karasawa, A., & Poolman, B. (2012). Functional Characterization of Amphipathic alpha-Helix in the Osmoregulatory ABC Transporter OpuA. Biochemistry, 51(25), 5142-5152. https://doi.org/10.1021/bi300451a
Birkner, J. P., Poolman, B., & Kocer, A. (2012). Hydrophobic gating of mechanosensitive channel of large conductance evidenced by single-subunit resolution. Proceedings of the National Academy of Sciences of the United States of America, 109(32), 12944-12949. https://doi.org/10.1073/pnas.1205270109
Poolman, B. (2012). On the Role of CBS Domains in Osmoregulatory ABC Transporters. Biophysical Journal, 102(3), 626a-626a. https://doi.org/10.1016/j.bpj.2011.11.3410
Berntsson, R. P. -A., ter Beek, J., Dosz-Majsnerowska, M., Duurkens, R. H., Puri, P., Poolman, B., & Slotboom, D-J. (2012). Structural divergence of paralogous S components from ECF-type ABC transporters. Proceedings of the National Academy of Sciences of the United States of America, 109(35), 13990-13995. https://doi.org/10.1073/pnas.1203219109
Berntsson, R. P. -A., Schuurman-Wolters, G. K., Dunny, G., Slotboom, D-J., & Poolman, B. (2012). Structure and Mode of Peptide Binding of Pheromone Receptor PrgZ. The Journal of Biological Chemistry, 287(44), 37165-37170. https://doi.org/10.1074/jbc.M112.386334
Schrauwers, A., & Poolman, B. (2012). Synthetische Biologie: De Mens als Schepper. Veen Magazines B.V.
Meinema, A. C., Poolman, B., & Veenhoff, L. M. (2012). The transport of integral membrane proteins across the nuclear pore complex. Nucleus-Austin, 3(4), 322-329. https://doi.org/10.4161/nucl.20439
Puri, P., Eckhardt, T., Franken, L., Fusetti, F., Stuart, M., Boekema, E., Kok, J., Kuipers, O., & Poolman, B. (2012). YfiA is necessary and sufficient for dimerization and inactivation of ribosomes in Lactococcus lactis. Molecular Biology of the Cell, 23, 1695.

2011

Franciosi, L., Govorukhina, N., Fusetti, F., Poolman, B., Hacken, N. T., Postma, D., & Bischoff, R. (2011). Biomarker Discovery In Chronic Obstructive Pulmonary Disease (COPD) Using Epithelial Lining Fluid: A Proteomic Approach. American Journal of Respiratory and Critical Care Medicine, 183(1), A1492-A1493.
Karasawa, A., Erkens, G. B., Berntsson, R. P. -A., Otten, R., Schuurman-Wolters, G. K., Mulder, F. A. A., & Poolman, B. (2011). Cystathionine beta-Synthase (CBS) Domains 1 and 2 Fulfill Different Roles in Ionic Strength Sensing of the ATP-binding Cassette (ABC) Transporter OpuA. The Journal of Biological Chemistry, 286(43), 37280-37291. https://doi.org/10.1074/jbc.M111.284059
Kolbe, A., Mercato, L. L. D., Abbasi, A. Z., Rivera Gil, P., Gorzini, S. J., Huibers, W., Poolman, B., Parak, W. J., & Herrmann, A. (2011). De Novo Design of Supercharged, Unfolded Protein Polymers, and Their Assembly into Supramolecular Aggregates. Macromolecular Rapid Communications, 32(2), 186-190. https://doi.org/10.1002/marc.201000491
Wolters, J. C., Roelfes, G., & Poolman, B. (2011). Design and synthesis of ATP-based nucleotide analogues and profiling of nucleotide-binding proteins. BIOCONJUGATE CHEMISTRY, 22(7), 1345-1353. https://doi.org/10.1021/bc100592q
Pinto, J. P. C., Kuipers, O. P., Marreddy, R. K. R., Poolman, B., & Kok, J. (2011). Efficient overproduction of membrane proteins in Lactococcus lactis requires the cell envelope stress sensor/regulator couple CesSR. PLoS ONE, 6(7), [21873]. https://doi.org/10.1371/journal.pone.0021873
Mika, J. T., Krasnikov, V., Bogaart, G. V. D., Haan, F. D., & Poolman, B. (2011). Evaluation of Pulsed-FRAP and Conventional-FRAP for Determination of Protein Mobility in Prokaryotic Cells. PLoS ONE, 6(9), [25664]. https://doi.org/10.1371/journal.pone.0025664
Berntsson, R. P-A., Thunnissen, A-M. W. H., Poolman, B., & Slotboom, D-J. (2011). Importance of a Hydrophobic Pocket for Peptide Binding in Lactococcal OppA. Journal of Bacteriology, 193(16), 4254-4256. https://doi.org/10.1128/JB.00447-11
Schaefer, L. V., de Jong, D. H., Holt, A., Rzepiela, A. J., de Vries, A. H., Poolman, B., Killian, J. A., & Marrink, S. J. (2011). Lipid packing drives the segregation of transmembrane helices into disordered lipid domains in model membranes. Proceedings of the National Academy of Sciences of the United States of America, 108(4), 1343-1348. https://doi.org/10.1073/pnas.1009362108
Meinema, A. C., Laba, J. K., Hapsari, R. A., Otten, R., Mulder, F. A. A., Kralt, A., van den Bogaart, G., Lusk, C. P., Poolman, B., & Veenhoff, L. M. (2011). Long Unfolded Linkers Facilitate Membrane Protein Import Through the Nuclear Pore Complex. Science, 333(6038), 90-93. https://doi.org/10.1126/science.1205741
Mika, J. T., & Poolman, B. (2011). Macromolecule diffusion and confinement in prokaryotic cells. Current Opinion in Biotechnology, 22(1), 117-126. https://doi.org/10.1016/j.copbio.2010.09.009
Bill, R. M., Henderson, P. J. F., Iwata, S., Kunji, E. R. S., Michel, H., Neutze, R., Newstead, S., Poolman, B., Tate, C. G., & Vogel, H. (2011). Overcoming barriers to membrane protein structure determination. Nature Biotechnology, 29(4), 335-340. https://doi.org/10.1038/nbt.1833
Kusters, I., van den Bogaart, G., Kedrov, A., Krasnikov, V., Fulyani, F., Poolman, B., & Driessen, A. J. M. (2011). Quaternary Structure of SecA in Solution and Bound to SecYEG Probed at the Single Molecule Level. Structure, 19(3), 430-439. https://doi.org/10.1016/j.str.2010.12.016
Marreddy, R. K. R., Geertsma, E. R., & Poolman, B. (2011). Recombinant Membrane Protein Production: Past, Present and Future. In J. Brnjas-Kraljević, & G. Pifat-Mrzljak (Eds.), Supramolecular Structure and Function 10 (10 ed., pp. 41-74). (Biomedical and Life Sciences; No. 10). Springer. https://doi.org/10.1007/978-94-007-0893-8_3
Backus, E. H. G., Kuiper, J., Engberts, J. B. F. N., Poolman, B., & Bonn, M. (2011). Reversible Optical Control of Monolayers on Water through Photoswitchable Lipids. Journal of Physical Chemistry B, 115(10), 2294-2302. https://doi.org/10.1021/jp1113619
Mika, J. T., Moiset, G., Cirac, A. D., Feliu, L., Bardaji, E., Planas, M., Sengupta, D., Marrink, S. J., & Poolman, B. (2011). Structural basis for the enhanced activity of cyclic antimicrobial peptides: The case of BPC194. Biochimica et Biophysica Acta-Biomembranes, 1808(9), 2197-2205. https://doi.org/10.1016/j.bbamem.2011.05.001
Poolman, B. (2011). Synthetische biologie: mogelijkheden en uitdagingen. In H. Smit, & P. Willemsen (Eds.), De Microcanon [Hoofdstuk 61] VBK Media.
Cirac, A. D., Moiset, G., Mika, J. T., Kocer, A., Salvador, P., Poolman, B., Marrink, S. J., & Sengupta, D. (2011). The Molecular Basis for Antimicrobial Activity of Pore-Forming Cyclic Peptides. Biophysical Journal, 100(10), 2422-2431. https://doi.org/10.1016/j.bpj.2011.03.057
Marreddy, R. K. R., Coelho Pinto, J., Wolters, J. C., Geertsma, E. R., Fusetti, F., Permentier, H. P., Kuipers, O. P., Kok, J., & Poolman, B. (2011). The response of Lactococcus lactis to membrane protein production. PLoS ONE, 6(8), [24060]. https://doi.org/10.1371/journal.pone.0024060
Erkens, G. B., Berntsson, R. P-A., Fulyani, F., Dosz-Majsnerowska, D-M., Vujicic - Zagar, A., ter Beek, J., Poolman, B., & Slotboom, D. J. (2011). The structural basis of modularity in ECF-type ABC transporters. Nature Structural & Molecular Biology, 18(7), 755-760. https://doi.org/10.1038/nsmb.2073

2010

Veenhoff, L. M., Meinema, A. C., & Poolman, B. (2010). A karyopherin acts in localized protein synthesis. Cell Cycle, 9(7), 1281-1285. https://doi.org/10.4161/cc.9.7.11110
Berntsson, R. P. -A., Smits, S. H. J., Schmitt, L., Slotboom, D-J., & Poolman, B. (2010). A structural classification of substrate-binding proteins. FEBS Letters, 584(12), 2606-2617. https://doi.org/10.1016/j.febslet.2010.04.043
Berntsson, R. P. -A., Smits, S. H. J., Schmitt, L., Slotboom, D-J., & Poolman, B. (2010). Addendum to "A structural classification of substrate-binding proteins" [FEBS Lett. 584 (2010) 2606-2617]. FEBS Letters, 584(20), 4373-4373. https://doi.org/10.1016/j.febslet.2010.09.044
Marreddy, R. K. R., Geertsma, E. R., Permentier, H. P., Coelho Pinto, J., Kok, J., & Poolman, B. (2010). Amino acid accumulation limits the overexpression of proteins in Lactococcus lactis. PLoS ONE, 5(4), [10317]. https://doi.org/10.1371/journal.pone.0010317
Gandhi, T., Fusetti, F., Wiederhold, E., Breitling, R., Poolman, B., & Permentier, H. P. (2010). Apex Peptide Elution Chain Selection: A New Strategy for Selecting Precursors in 2D-LC-MALDI-TOF/TOF Experiments on Complex Biological Samples. Journal of Proteome Research, 9(11), 5922-5928. https://doi.org/10.1021/pr1006944
M. Linares, D., Geertsma, E. R., & Poolman, B. (2010). Evolved Lactococcus lactis Strains for Enhanced Expression of Recombinant Membrane Proteins. Journal of Molecular Biology, 401(1), 45-55. https://doi.org/10.1016/j.jmb.2010.06.002
Linares, D. M., Kok, J., & Poolman, B. (2010). Genome Sequences of Lactococcus lactis MG1363 (Revised) and NZ9000 and Comparative Physiological Studies. Journal of Bacteriology, 192(21), 5806 - 5812. https://doi.org/10.1128/JB.00533-10
Ramadurai, S., Holt, A., Schafer, L. V., Krasnikov, V. V., Rijkers, D. T. S., Marrink, S. J., Killian, J. A., & Poolman, B. (2010). Influence of Hydrophobic Mismatch and Amino Acid Composition on the Lateral Diffusion of Transmembrane Peptides. Biophysical Journal, 99(5), 1447-1454. https://doi.org/10.1016/j.bpj.2010.05.042
Ramadurai, S., Duurkens, H., Krasnikov, V. V., & Poolman, B. (2010). Lateral Diffusion of Membrane Proteins: Consequences of Hydrophobic Mismatch and Lipid Composition. Biophysical Journal, 99(5), 1482-1489. https://doi.org/10.1016/j.bpj.2010.06.036
Wolters, J. C., Berntsson, R. P-A., Gul, N., Karasawa, A., Thunnissen, A-M. W. H., Slotboom, D-J., & Poolman, B. (2010). Ligand Binding and Crystal Structures of the Substrate-Binding Domain of the ABC Transporter OpuA. PLoS ONE, 5(4), [10361]. https://doi.org/10.1371/journal.pone.0010361
Mika, J. T., van den Bogaart, G., Veenhoff, L., Krasnikov, V., & Poolman, B. (2010). Molecular sieving properties of the cytoplasm of Escherichia coli and consequences of osmotic stress. Molecular Microbiology, 77(1), 200-207. https://doi.org/10.1111/j.1365-2958.2010.07201.x
Maddalena, F., Kuiper, M. J., Poolman, B., Brouwer, F., Hummelen, J. C., de Leeuw, D. M., de Boer, B., & Blom, P. W. M. (2010). Organic field-effect transistor-based biosensors functionalized with protein receptors. Journal of Applied Physics, 108(12), 124501-1-124501-4. [124501]. https://doi.org/10.1063/1.3518681
Wiederhold, E., Veenhoff, L. M., Poolman, B., & Slotboom, D. J. (2010). Proteomics of Saccharomyces cerevisiae Organelles. Molecular & Cellular Proteomics, 9(3), 431-445. https://doi.org/10.1074/mcp.R900002-MCP200
Kusters, I., Bogaart, G. V. D., de Wit, J., Krasnikov, V., Poolman, B., & Driessen, A. (2010). Purification and Functional Reconstitution of the Bacterial Protein Translocation Pore, the SecYEG Complex. In A. Economou (Ed.), Protein Secretion: Methods and Protocols (Vol. 619, pp. 131-143). Humana Press. https://doi.org/10.1007/978-1-60327-412-8_8

2009

Geertsma, E. R., & Poolman, B. (2010). Production of Membrane Proteins in Escherichia coli and Lactococcus lactis. Methods in Molecular Biology, 601, 17-38. https://doi.org/10.1007/978-1-60761-344-2_2
Kuiper, J. M., Pluta, R., Huibers, W. H. C., Fusetti, F., Geertsma, E. R., & Poolman, B. (2009). A method for site-specific labeling of multiple protein thiols. Protein Science, 18(5), 1033-1041. https://doi.org/10.1002/pro.113
Boumann, H. A., Longo, M. L., Stroeve, P., Poolman, B., Hopmans, E. C., Stuart, M. C. A., Damste, J. S. S., & Schouten, S. (2009). Biophysical properties of membrane lipids of anammox bacteria: I. Ladderane phospholipids form highly organized fluid membranes. Biochimica et Biophysica Acta-Biomembranes, 1788(7), 1444-1451. https://doi.org/10.1016/j.bbamem.2009.04.008
Boumann, H. A., Stroeve, P., Longo, M. L., Poolman, B., Kuiper, J. M., Hopmans, E. C., Jetten, M. S. M., Damste, J. S. S., & Schouten, S. (2009). Biophysical properties of membrane lipids of anammox bacteria: II. Impact of temperature and bacteriohopanoids. Biochimica et Biophysica Acta-Biomembranes, 1788(7), 1452-1457. https://doi.org/10.1016/j.bbamem.2009.04.005
Kruegel, U., Veenhoff, L. M., Langbein, J., Wiederhold, E., Liesche, J., Friedrich, T., Grimm, B., Martinoia, E., Poolman, B., & Kuehn, C. (2009). Correction to: Transport and Sorting of the Solanum tuberosum Sucrose Transporter SUT1 Is Affected by Posttranslational Modification (vol 20, pg 2497, 2008). Plant Cell, 21(12), 4059-4060. https://doi.org/10.1105/tpc.109.211260
Vos, E. P. P., ter Horst, R., Poolman, B., & Broos, J. (2009). Domain complementation studies reveal residues critical for the activity of the mannitol permease from Escherichia coli. Biochimica et Biophysica Acta-Biomembranes, 1788(2), 581-586. https://doi.org/10.1016/j.bbamem.2008.10.008
Mahmood, N. A. B. N., Biemans-Oldehinkel, E., & Poolman, B. (2009). Engineering of Ion Sensing by the Cystathionine beta-Synthase Module of the ABC Transporter OpuA. The Journal of Biological Chemistry, 284(21), 14368-14376. https://doi.org/10.1074/jbc.M901238200
Ramadurai, S., Holt, A., Krasnikov, V., van den Bogaart, G., Killian, J. A., & Poolman, B. (2009). Lateral Diffusion of Membrane Proteins. Journal of the American Chemical Society, 131(35), 12650-12656. https://doi.org/10.1021/ja902853g
Kiel, J. A. K. W., van den Berg, M. A., Fusetti, F., Poolman, B., Bovenberg, R. A. L., Veenhuis, M., & van der Klei, I. J. (2009). Matching the proteome to the genome: the microbody of penicillin-producing Penicillium chrysogenum cells. FUNCTIONAL & INTEGRATIVE GENOMICS, 9(2), 167-184. https://doi.org/10.1007/s10142-009-0110-6
Lundbaek, J. A., Tidemand-Lichtenberg, P., Nielsen, C. H., Kuiper, J. M., Engberts, J. B., Poolman, B., & Abdali, S. (2009). Mechanical Pull On A Guest Molecule By A Photoresponsive Lipid Bilayer. In EPRINTS-BOOK-TITLE (pp. 151a-151a). University of Groningen, Stratingh Institute for Chemistry.
Bogaart, G. V. D., Meinema, A. C., Krasnikov, V., Veenhoff, L. M., & Poolman, B. (2009). Nuclear transport factor directs localization of protein synthesis during mitosis. Nature Cell Biology, 11(3), 350-U269. https://doi.org/10.1038/ncb1844
Ellen, A. F., Albers, S-V., Huibers, W., Pitcher, A., Hobel, C. F. V., Schwarz, H., Folea, M., Schouten, S., Boekema, E. J., Poolman, B., & Driessen, A. J. M. (2009). Proteomic analysis of secreted membrane vesicles of archaeal Sulfolobus species reveals the presence of endosome sorting complex components. Extremophiles, 13(1), 67-79. https://doi.org/10.1007/s00792-008-0199-x
Berntsson, R. P. -A., Oktaviani, N. A., Fusetti, F., Thunnissen, A-M. W. H., Poolman, B., & Slotboom, D-J. (2009). Selenomethionine incorporation in proteins expressed in Lactococcus lactis. Protein Science, 18(5), 1121-1127. https://doi.org/10.1002/pro.97
Spitzer, J., & Poolman, B. (2009). The Role of Biomacromolecular Crowding, Ionic Strength, and Physicochemical Gradients in the Complexities of Life's Emergence. Microbiology and Molecular Biology Reviews, 73(2), 371-388. https://doi.org/10.1128/MMBR.00010-09
Berntsson, R. P-A., Doeven, M. K., Fusetti, F., Duurkens, R. H., Sengupta, D., Marrink, S-J., Thunnissen, A-M. W. H., Poolman, B., & Slotboom, D-J. (2009). The structural basis for peptide selection by the transport receptor OppA. EMBO Journal, 28(9), 1332-1340. https://doi.org/10.1038/emboj.2009.65
Mulligan, C., Geertsma, E. R., Severi, E., Kelly, D. J., Poolman, B., & Thomas, G. H. (2009). The substrate-binding protein imposes directionality on an electrochemical sodium gradient-driven TRAP transporter. Proceedings of the National Academy of Sciences of the United States of America, 106(6), 1778-1783. https://doi.org/10.1073/pnas.0809979106
Wiederhold, E., Gandhi, T., Permentier, H. P., Breitling, R., Poolman, B., & Slotboom, D. J. (2009). The Yeast Vacuolar Membrane Proteome. Molecular & Cellular Proteomics, 8(2), 380-392. https://doi.org/10.1074/mcp.M800372-MCP200

2008

van den Bogaart, G., Kusters, I., Velasquez, J., Mika, J. T., Krasnikov, V., Driessen, A. J. M., & Poolman, B. (2008). Dual-color fluorescence-burst analysis to study pore formation and protein-protein interactions. Methods., 46(2), 123-130. https://doi.org/10.1016/j.ymeth.2008.06.016
Geertsma, E. R., & Poolman, B. (2008). Means and methods for cloning nucleic acid sequences. (Patent No. WO2008147193).
Geertsma, E. R., Mahmood, N. A. B. N., Schuurman-Wolters, G. K., & Poolman, B. (2008). Membrane reconstitution of ABC transporters and assays of translocator function. Nature protocols, 3(2), 256-266. [2]. https://doi.org/10.1038/nprot.2007.519
Poolman, B. (2008). New and emerging methods in membrane protein research. Methods, 46(2), 47-47. https://doi.org/10.1016/j.ymeth.2008.10.025
van den Bogaart, G., Guzman, J. V., Mika, J. T., & Poolman, B. (2008). On the Mechanism of Pore Formation by Melittin. The Journal of Biological Chemistry, 283(49), 33854-33857. https://doi.org/10.1074/jbc.M805171200
Doeven, M. K., Bogaart, G. V. D., Krasnikov, V., & Poolman, B. (2008). Probing receptor-translocator interactions in the oligopeptide ABC transporter by fluorescence correlation spectroscopy. Biophysical Journal, 94(10), 3956-3965. https://doi.org/10.1529/biophysj.107.120964
Geertsma, E. R., Groeneveld, M., Slotboom, D-J., & Poolman, B. (2008). Quality control of overexpressed membrane proteins. Proceedings of the National Academy of Sciences of the United States of America, 105(15), 5722-5727. https://doi.org/10.1073/pnas.0802190105
Kruegel, U., Veenhoff, L. M., Langbein, J., Wiederhold, E., Liesche, J., Friedrich, T., Grimm, B., Martinoia, E., Poolman, B., Kuehn, C., Krügel, U., & Kühn, C. (2008). Transport and Sorting of the Solanum tuberosum Sucrose Transporter SUT1 Is Affected by Posttranslational Modification. Plant Cell, 20(9), 2497-2513. https://doi.org/10.1105/tpc.108.058271
Kuipers, O. P., Poolman, B., & Hugenholtz, J. (2008). 9th International Symposium on Lactic Acid Bacteria. Applied and environmental microbiology, 74(15), 4589.
Kuipers, O. P., Poolman, B., & Hugenholtz, J. (2008). 9th International Symposium on lactic acid bacteria. Applied and environmental microbiology, 74(15), 4589-4589. https://doi.org/10.1128/AEM.01384-08

2007

Poolman, B., Geertsma, E. R., & Slotboom, D. J. (2007). A missing link in membrane protein evolution. Science, 315(5816), 1229 - 1231. https://doi.org/10.1126/science.1140073
Wiederhold, E., & Poolman, B. (2007). Acid- and proline-directed peptide fragmentation as a simple strategy for improved identification success of low quality MALDI-TOF/TOF spectra. Proteomics.
Boumann, H., Longo, M., Stroeve, P., Jetten, M., Poolman, B., Sinninghe Damsté, J., & Schouten, S., (2007). Biophysical properties of ladderane lipids derived from anammox bacteria, 1 p.
Poolman, B., Geertsma, E., & Slotboom, D-J. (2007). Controversy Over EmrE Structure. Science, 317(5839), 750 - 751. https://doi.org/10.1126/science.317.5839.748d
Poolman, B., Geertsma, E., & Slotboom, D-J. (2007). Controversy over EmrE structure - Response. Science, 317(5839), 750-751.
van den Bogaart, G., Mika, J., Krasnikov, V. V., & Poolman, B. (2007). Dual-color fluorescence-burst analysis to probe macromole cule efflux through protein channels and peptide pokes. Biophysical Journal, 113A - 113A.
van den Bogaart, G., Krasnikov, V., & Poolman, B. (2007). Dual-color fluorescence-burst analysis to probe protein efflux through the mechanosensitive channel MscL. Biophysical Journal, 92(4), 1233-1240. https://doi.org/10.1529/biophysj.106.088708
Brooijmans, R. J. W., Poolman, B., Schuurman-Wolters, G. K., de Vos, W. M., & Hugenholtz, J. (2007). Generation of a membrane potential by Lactococcus lactis through aerobic electron transport. Journal of Bacteriology, 189(14), 5203-5209. https://doi.org/10.1128/JB.00361-07
Geertsma, E. R., & Poolman, B. (2007). High-throughput cloning and expression in recalcitrant bacteria. Nature Methods, 4(9), 705-707. https://doi.org/10.1038/NMETH1073
van den Bogaart, G., Hermans, N., Krasnikov, V., de Vries, A. H., & Poolman, B. (2007). On the decrease in lateral mobility of phospholipids by sugars. Biophysical Journal, 92(5), 1598-1605. https://doi.org/10.1529/biophysj.106.096461
Spitzer, J., & Poolman, B. (2007). On the Heuristic Distributions of 1:1 and 1:2 Electrolytes in the “Crowded” Cytoplasm. unknown / not applicable / onbekend / n.v.t., 7 - 20.
Bogaart, G. V. D., Hermans, N., Krasnikov, V., & Poolman, B. (2007). Protein mobility and diffusive barriers in Escherichia coli: consequences of osmotic stress. Molecular Microbiology, 64(3), 858-871. https://doi.org/10.1111/j.1365-2958.2007.05705.x
Bogaart, G. V. D., Mika, J. T., Krasnikov, V., & Poolman, B. (2007). The lipid dependence of melittin action investigated by dual-color fluorescence burst analysis. Biophysical Journal, 93(1), 154-163. https://doi.org/10.1529/biophysj.107.106005

2006

Biemans-Oldehinkel, E., Mahmood, N. A. B. N., & Poolman, B. (2006). A sensor for intracellular ionic strength. Proceedings of the National Academy of Sciences, 103(28), 10624 - 10629. https://doi.org/10.1073/pnas.0603871103
Biemans-Oldehinkel, E., Doeven, MK., & Poolman, B. (2006). ABC transporter architecture and regulatory roles of accessory domains. FEBS Letters, 580(4), 1023-1035. https://doi.org/10.1016/j.febslet.2005.11.079
Gandy, S., Doeven, M. K., & Poolman, B. (2006). Alzheimer disease: presenilin springs a leak. Nature Medicine, 12(10), 1121-1123. https://doi.org/10.1038/nm1006-1121
Mahmood, N. A. B. N., Biemans-Oldehinkel, E., Patzlaff, J. S., Schuurman-Wolters, G. K., & Poolman, B. (2006). Ion specificity and ionic strength dependence of the osmoregulatory ABC transporter OpuA. The Journal of Biological Chemistry, 281(40), 29830-29839. https://doi.org/10.1074/jbc.M604907200
Wiederhold, E., Slotboom, D. J., & Poolman, B. (2006). Membrane proteomics of S-cerevisiae vacuoles. Molecular & Cellular Proteomics, 5(10), S161 - S161.
Borst, P., Zelcer, N., van de Wetering, K., & Poolman, B. (2006). On the putative co-transport of drugs by multidrug resistance proteins. FEBS Letters, 580(4), 1085-1093. https://doi.org/10.1016/j.febslet.2005.12.039
Doeven, M. K., van den Bogaart, G., Krasnikov, V. V., & Poolman, B. (2006). Probing the catalytic cycle of the oligopeptide ABC transporter by fluorescence correlation spectroscopy. Biophysical Journal.
Veldhuis, G., Hink, M., Krasnikov, V., Van Den Bogaart, G., Hoeboer, J., Visser, A. J. W. G., Broos, J., & Poolman, B. (2006). The oligomeric state and stability of the mannitol transporter, EnzymeII(mtl), from Escherichia coli: A fluorescence correlation spectroscopy study. Protein Science, 15(8), 1977-1986. https://doi.org/10.1110/ps.062113906
Burgess, CM., Slotboom, DJ., Geertsma, ER., Duurkens, H., Poolman, B., & van Sinderen, D. (2006). The riboflavin transporter RibU in Lactococcus lactis: Molecular characterization of gene expression and the transport mechanism. Journal of Bacteriology, 188(8), 2752-2760. https://doi.org/10.1128/JB.188.8.2752-2760.2006

2005

Doeven, M. K., Folgering, J. H. A., Krasnikov, V., Geertsma, E. R., Bogaart, G. V. D., & Poolman, B. (2005). Distribution, lateral mobility and function of membrane proteins incorporated into giant unilamellar vesicles. Biophysical Journal, 88(2), 1134-1142. https://doi.org/10.1529/biophysj.104.053413
Spitzer, JJ., & Poolman, B. (2005). Electrochemical structure of the crowded cytoplasm. Trends in Biochemical Sciences, 30(10), 536-541. https://doi.org/10.1016/j.tibs.2005.08.002
Folgering, JHA., Wolters, JC., & Poolman, B. (2005). Engineering covalent oligomers of the mechanosensitive channel of large conductance from Escherichia coli with native conductance and gating characteristics. Protein Science, 14(12), 2947-2954. https://doi.org/10.1110/ps.051679005
Poolman, B., Doeven, M. K., Geertsma, E. R., Biemans‐Oldehinkel, E., Konings, W. N., & Rees, D. C. (2005). Functional Analysis of Detergent‐Solubilized and Membrane‐Reconstituted ATP‐Binding Cassette Transporters. In EPRINTS-BOOK-TITLE University of Groningen, Groningen Biomolecular Sciences and Biotechnology Institute (GBB).
Burgess, C. M., Geertsma, E. R., Duurkens, R. H., Slotboom, D. J., & Poolman, B. (2005). Functional characterisation of the riboflavin transporter in Lactococcus lactis. Journal of Bacteriology, 188, 2752 - 2760.
Geertsma, ER., Duurkens, RH., Poolman, B., & Duurkens, R. H. (2005). Functional interactions between the subunits of the lactose transporter from Streptococcus thermophilus. Journal of Molecular Biology, 350(1), 102-111. https://doi.org/10.1016/j.jmb.2005.04.047
Borths, EL., Poolman, B., Hvorup, RN., Locher, KP., Rees, DC., Hvorup, R. N., Locher, K. P., & Rees, D. C. (2005). In vitro functional characterization of BtuCD-F, the Escherichia coli ABC transporter for vitamin B-12 uptake. Biochemistry, 44(49), 16301-16309. https://doi.org/10.1021/bi0513103
Folgering, J. H. A., Moe, P. C., Schuurman-Wolters, G. K., Blount, P., & Poolman, B. (2005). Lactococcus lactis Uses MscL as Its Principal Mechanosensitive Channel. The Journal of Biological Chemistry, 280(10), 8784 - 8792. https://doi.org/10.1074/jbc.M411732200
Doeven, MK., Kok, J., & Poolman, B. (2005). Specificity and selectivity determinants of peptide transport in Lactococcus lactis and other microorganisms. Molecular Microbiology, 57(3), 640-649. https://doi.org/10.1111/j.1365-2958.2005.04698.x
Veldhuis, G., Broos, J., Poolman, B., & Scheek, R. M. (2005). Stoichiometry and Substrate Affinity of the Mannitol Transporter, EnzymeIImtl, from Escherichia coli. Biophysical Journal, 89(1), 201 - 210. https://doi.org/10.1529/biophysj.105.062877
Caparon, M. G., Poolman, B., & Podbielski, A. (2005). Streptococcal peptide transmembrane transport: description of transport systems and biological consequences. Streptococcal Genetics ASM, epub.
Schuurman-Wolters, G. K., & Poolman, B. (2005). Substrate Specificity and Ionic Regulation of GlnPQ from Lactococcus lactis. An ATP-Binding Cassette Transporter with Four Extracytoplasmic Substrate-Binding Domains. The Journal of Biological Chemistry, 280(25), 23785 - 23790. https://doi.org/10.1074/jbc.M500522200
Veldhuis, G., Gabellieri, E., Poolman, B., Strambini, G. B., & Broos, J. (2005). Substrate-induced Conformational Changes in the Membrane-embedded IICmtl-domain of the Mannitol Permease from Escherichia coli, EnzymeIImtl, Probed by Tryptophan Phosphorescence Spectroscopy. The Journal of Biological Chemistry, 280(42), 35148 - 35156. https://doi.org/10.1074/jbc.M507061200
Geertsma, E. R., Duurkens, R. H., & Poolman, B. (2005). The Activity of the Lactose Transporter from Streptococcus thermophilus Is Increased by Phosphorylated IIA and the Action of β-Galactosidase. Biochemistry, 44(48), 15889 - 15897. https://doi.org/10.1021/bi051638w
Vervoort, E. B., Bultema, J. B., Schuurman-Wolters, G. K., Geertsma, E. R., Broos, J., & Poolman, B. (2005). The first cytoplasmic loop of the mannitol permease from Escherichia coli is accessible for sulfhydryl reagents from the periplasmic side of the membrane. Journal of Molecular Biology, 346(3), 733 - 743. https://doi.org/10.1016/j.jmb.2004.12.011
Wang, N. V., Shi, FX., Wosten, HAB., Hektor, H., Poolman, B., Robillard, GT., Wang, X., & Shi, F. (2005). The SC3 hydrophobin self-assembles into a membrane with distinct mass transfer properties. Biophysical Journal, 88(5), 3434-3443. https://doi.org/10.1529/biophysj.104.057794
Sanz, Y., Lanfermeijer, F. C., Hellendoorn, M., Kok, J., Konings, W. N., & Poolman, B. (2005). Two homologous oligopeptide binding protein genes (oppA) in Lactococcus lactis MG1363 (vol 97, pg 9, 2004). International Journal of Food Microbiology, 102(1), 121-121. https://doi.org/10.1016/j.ijfoodmicro.2005.03.001

2004

Poolman, B., Spitzer, J. J., Wood, J. A., & Wood, J. M. (2004). Bacterial osmosensing: roles of membrane structure and electrostatics in lipid-protein and protein-protein interactions: roles of membrane structure and electrostatics in lipid–protein and protein–protein interactions. Biochimica et Biophysica Acta-Biomembranes, 1666(1-2), 88 - 104. https://doi.org/10.1016/j.bbamem.2004.06.013
Veldhuis, G., Broos, J., Poolman, B., & Scheek, RM. (2004). Evaluation of the flow-dialysis technique for analysis of protein-ligand interactions: An experimental and a Monte Carlo study. Biophysical Journal, 86(4), 1959-1968. https://doi.org/10.1016/S0006-3495(04)74259-9
Schuurman-Wolters, G. K., & Poolman, B. (2004). GlnPQ from Lactococcus Lactis: an ABC tansporter with four extracytoplasmic substratebinding domains. The Journal of Biological Chemistry.
Folgering, J. H. A., Kuiper, J. M., Vries, A. H. D., Engberts, J. B. F. N., & Poolman, B. (2004). Lipid-Mediated Light Activation of a Mechanosensitive Channel of Large Conductance. Langmuir, 20(17), 6985 - 6987. https://doi.org/10.1021/la048942v
Wang, X., Permentier, H. P., Rink, R., Kruijtzer, J. A. W., Liskamp, R. M. J., Wösten, H. A. B., Poolman, B., & Robillard, G. T. (2004). Probing the Self-Assembly and the Accompanying Structural Changes of Hydrophobin SC3 on a Hydrophobic Surface by Mass Spectrometry. Biophysical Journal, 87(3), 1919 - 1928. https://doi.org/10.1529/biophysj.104.041616
Doeven, M. K., Abele, R., Tampé, R., & Poolman, B. (2004). The Binding Specificity of OppA Determines the Selectivity of the Oligopeptide ATP-binding Cassette Transporter. The Journal of Biological Chemistry, 279(31), 32301 - 32307. https://doi.org/10.1074/jbc.M404343200
Sanz, Y., Lanfermeijer, F. C., Hellendoorn, M., Kok, J., Konings, W. N., & Poolman, B. (2004). Two homologous oligopeptide binding protein genes (oppA) in Lactococcus lactis MG1363. International Journal of Food Microbiology, 97(1), 9 - 15. https://doi.org/10.1016/j.ijfoodmicro.2004.04.003

2003

Friesen, R. H. E., Poolman, B., Feringa, B. L., & Engberts, J. (2003). IPC No. A61K 9/ 127 A I. Delivery of small hydrophilic molecules packaged into lipid vesicles. (Patent No. US2003118636).
Geertsma, E. R., Duurkens, R. H., & Poolman, B. (2003). Identification of the dimer interface of the lactose transport protein from Streptococcus thermophilus. Journal of Molecular Biology, 332(5), 1165 - 1174. https://doi.org/10.1016/j.jmb.2003.07.010
Kunji, ERS., Slotboom, DJ., & Poolman, B. (2003). Lactococcus lactis as host for overproduction of functional membrane proteins. Biochimica et Biophysica Acta-Biomembranes, 1610(1), 97-108. https://doi.org/10.1016/S0005-2736(02)00712-5
Biemans-Oldehinkel, E., & Poolman, B. (2003). On the role of the two extracytoplasmic substrate-binding domains in the ABC transporter OpuA. EMBO Journal, 22(22), 5983 - 5993. https://doi.org/10.1093/emboj/cdg581
Kahya, N., Scherfeld, D., Bacia, K., Poolman, B., & Schwille, P. (2003). Probing lipid mobility of raft-exhibiting model membranes by fluorescence correlation spectroscopy. The Journal of Biological Chemistry, 278(30), 28109-28115. https://doi.org/10.1074/jbc.M302969200
Sanz, Y., Toldra, F., Renault, P., & Poolman, B. (2003). Specificity of the second binding protein of the peptide ABC-transporter (Dpp) of Lactococcus lactis IL1403. FEMS Microbiology Letters, 227(1), 33-38. https://doi.org/10.1016/S0378-1097(03)00662-1
Poolman, B., & van der Heide, T. (2003). Structure and function of osmoregulated ABC transporters. In ABC proteins: from bacteria to man (pp. 263 - 275). (ABC proteins: from bacteria to man). Academic Press.
Patzlaff, JS., Poolman, B., & Patzlaff, J. S. (2003). The ATP/Substrate stoichiometry of the ATP-binding cassette (ABC) transporter OpuA. The Journal of Biological Chemistry, 278(32), 29546-29551. https://doi.org/10.1074/jbc.M304796200

2002

van der Heide, T., & Poolman, B. (2002). ABC transporters: one, two or four extracytoplasmic substrate- binding sites? Embo Reports, 3(10), 938-943. https://doi.org/10.1093/embo-reports/kvf201
Montfort, B. A. V., Doeven, M. K., Canas, B., Veenhoff, L. M., Poolman, B., & Robillard, G. T. (2002). Combined in-gel tryptic digestion and CNBr cleavage for the generation of peptide maps of an integral membrane protein with MALDI-TOF mass spectrometry. Biochimica et Biophysica Acta-Bioenergetics, 1555(1-3), 111 - 115. https://doi.org/10.1016/S0005-2728(02)00264-5
Poolman, B., Blount, P., Folgering, J. H. A., Friesen, R. H. E., Moe, P. C., & Heide, T. V. D. (2002). How do membrane proteins sense water stress? Molecular Microbiology, 44(4), 889 - 902. https://doi.org/10.1046/j.1365-2958.2002.02894.x
Kahya, N., Wiersma, D. A., & Poolman, B. (2002). Morphology and fine structure of membranes upon osmotic upshifts. Journal of Fluorescence, 12(2), 193 - 196. https://doi.org/10.1023/A:1016852531869
Heuberger, E. H. M. L., Veenhoff, L. M., Duurkens, R. H. T., Friesen, R. H. E., & Poolman, B. (2002). Oligomeric state of membrane transport proteins analyzed with blue native electrophoresis and analytical ultracentrifugation. Journal of Molecular Biology, 317(4), 591-600. https://doi.org/10.1006/jmbi.2002.5416
Veenhoff, L. M., Heuberger, E. H. M. L., & Poolman, B. (2002). Quaternary structure and function of transport proteins. Trends in Biochemical Sciences, 27(5), 242 - 249. https://doi.org/10.1016/S0968-0004(02)02077-7
Kahya, N., Wiersma, D. A., Poolman, B., & Hoekstra, D. (2002). Spatial Organization of Bacteriorhodopsin in Model Membranes: Light-Induced Mobility Changes. The Journal of Biological Chemistry, 277(42), 39304-39311. https://doi.org/10.1074/jbc.M202635200
Wang, X., Vocht, M. L. D., Poolman, B., Robillard, G. T., Wang, N. V., & Jonge, J. D. (2002). Structural changes and molecular interactions of hydrophobin SC3 in solution and on a hydrophobic surface. Protein Science, 11(5), 1172 - 1181. https://doi.org/10.1110/ps.4530102
Poolman, B. (2002). Transporters and their roles in LAB cell physiology. Antonie Van Leeuwenhoek: International Journal of General and Molecular Microbiology, 82(1-4), 147 - 164.
Poolman, B. (2002). Transporters and their roles in LAB cell physiology. Clinical and Experimental Pharmacology and Physiology, 29(11).

2001

van Montfort, B. A., Schuurman-Wolters, G. K., Duurkens, R. H. T., Mensen, R., Poolman, B., & Robillard, G. T. (2001). Cysteine cross-linking defines part of the dimer and B/C domain interface of the Escherichia coli mannitol permease. The Journal of Biological Chemistry, 276(16), 12756 - 12763. https://doi.org/10.1074/jbc.M010728200
Sanz, Y., Lanfermeijer, F. C., Renault, P., Bolotin, A., Konings, W. N., & Poolman, B. (2001). Genetic and functional characterization of dpp genes encoding a dipeptide transport system in Lactococcus lactis. Archives of Microbiology, 175(5), 334 - 343. https://doi.org/10.1007/s002030100270
Gunnewijk, M. G. W., van den Bogaard, P. T. C., Veenhoff, L. M., Heuberger, E. H. M. L., de Vos, W. M., Kleerebezem, M., Kuipers, O. P., & Poolman, B. (2001). Hierarchical control versus autoregulation of carbohydrate utilization in bacteria. Journal of Molecular Microbiology and Biotechnology, 3(3), 401 - 413.
van Montfort, B. A., Schuurman-Wolters, G. K., Wind, J., Broos, J., Robillard, G. T., & Poolman, B. (2001). Mapping of the dimer interface of the Escherichia coli mannitol permease by cysteine cross-linking. The Journal of Biological Chemistry, 277(17), 14717 - 14723. https://doi.org/10.1074/jbc.M201533200
van der Heide, T., Stuart, M. C. A., & Poolman, B. (2001). On the osmotic signal and osmosensing mechanism of an ABC transport system for glycine betaine. EMBO Journal, 20(24), 7022 - 7032. https://doi.org/10.1093/emboj/20.24.7022
Wood, J. M., Bremer, E., Csonka, L. N., Kraemer, R., Poolman, B., van der Heide, T., & Smith, L. T. (2001). Osmosensing and osmoregulatory compatible solute accumulation by bacteria. Comparative Biochemistry and Physiology A-Molecular and Integrative Physiology, 130(3), 437 - 460. https://doi.org/10.1016/S1095-6433(01)00442-1
Detmers, F. J. M., Lanfermeijer, F. C., & Poolman, B. (2001). Peptides and ATP binding cassette peptide transporters. Research in Microbiology, 152(3-4), 245 - 258. https://doi.org/10.1016/S0923-2508(01)01196-2
Ward, A., Hoyle, C., Palmer, S., O'Reilly, J., Griffith, J., Pos, M., Morrison, S., Poolman, B., Gwynne, M., & Henderson, P. J. F. (2001). Prokaryote multidrug efflux proteins of the major facilitator superfamily: Amplified expression, purification and characterisation: Amplified expression, purification and characterisation. Journal of Molecular Microbiology and Biotechnology, 3(2), 193 - 200.
Brondijk, T. H. C., Konings, W. N., & Poolman, B. (2001). Regulation of maltose transport in Saccharomyces cerevisae. Archives of Microbiology, 176(1-2), 96 - 105. https://doi.org/10.1007/s002030100300
Veenhoff, L. M., Heuberger, E. H. M. L., & Poolman, B. (2001). The lactose transport protein is a cooperative dimer with two sugar translocation pathways. EMBO Journal, 20(12), 3056 - 3062. https://doi.org/10.1093/emboj/20.12.3056
Heuberger, E. H. M. L., Smits, E., & Poolman, B. (2001). Xyloside Transport by XylP, a Member of the Galactoside-Pentoside-Hexuronide Family. The Journal of Biological Chemistry, 276(37), 34465 - 34472. https://doi.org/10.1074/jbc.M105460200

2000

Heuberger, E. H. M. L., & Poolman, B. (2000). A spectroscopic assay for the analysis of carbohydrate transport reactions. European Journal of Biochemistry, 267(1), 228 - 234. https://doi.org/10.1046/j.1432-1327.2000.00993.x
Poolman, B., Fang, G., Friesen, R. H. E., van der Heide, T., Heuberger, E. H. M. L., Klunder, B., Veenhof, L. M., & Knol, J. (2000). Amplified gene expression in gram-positive bacteria, and membrane reconstitution of purified membrane transport proteins. In Membrane transport: a practical appraoch (Membrane transport: a practical appraoch). Oxford University Press.
Veenhoff, L. M., Geertsma, E. R., Poolman, B., & Knol, J. (2000). Close Approximation of Putative α-Helices II, IV, VII, X, and XI in the Translocation Pathway of the Lactose Transport Protein of Streptococcus thermophilus. The Journal of Biological Chemistry, 275(31), 23834 - 23840. https://doi.org/10.1074/jbc.M001343200
Detmers, F. J. M., Lanfermeijer, F. C., Abele, R., Jack, R. W., Tampe, R., Konings, W. N., & Poolman, B. (2000). Combinatorial peptide libraries reveal the ligand-binding mechanism of the oligopeptide receptor OppA of Lactococcus lactis. Proceedings of the National Academy of Sciences of the United States of America, 97(23), 12487-12492. https://doi.org/10.1073/pnas.220308797
van der Heide, T., & Poolman, B. (2000). Glycine betaine transport in Lactococcus lactis is osmotically regulated at the level of expression and translocation activity. Journal of Bacteriology, 182(1), 203 - 206. https://doi.org/10.1128/JB.182.1.203-206.2000
Gunnewijk, M. G. W., & Poolman, B. (2000). HPr(His~P)-mediated Phosphorylation Differently Affects Counterflow and Proton Motive Force-driven Uptake via the Lactose Transport Protein of Streptococcus thermophilus. The Journal of Biological Chemistry, 275(44), 34080 - 34085. https://doi.org/10.1074/jbc.M003513200
Sanz, Y., Lanfermeijer, F. C., Konings, W. N., & Poolman, B. (2000). Kinetics and structural requirements for the binding protein of the di-tripeptide transport system of Lactococcus lactis. Biochemistry, 39(16), 4855 - 4862. https://doi.org/10.1021/bi992720s
Fang, G., Konings, W. N., & Poolman, B. (2000). Kinetics and substrate specificity of membrane-reconstituted peptide transporter DtpT of Lactococcus lactis. Journal of Bacteriology, 182(9), 2530 - 2535. https://doi.org/10.1128/JB.182.9.2530-2535.2000
Konings, W. N., Kok, J., Kuipers, O. P., & Poolman, B. (2000). Lactic acid bacteria: the bugs of the new millennium. Current Opinion in Microbiology, 3(3), 276-282. https://doi.org/10.1016/S1369-5274(00)00089-8
Lanfermeijer, F. C., Detmers, F. J. M., Konings, W. N., & Poolman, B. (2000). On the binding mechanism of the peptide receptor of the oligopeptide transport system of Lactococcus lactis. EMBO Journal, 19(14), 3649 - 3656.
Lanfermeijer, F. C., Detmers, F. J. M., Konings, W. N., & Poolman, B. (2000). On the binding mechanism of the peptide receptor of the oligopeptide transport system of Lactococcus lactis. Proceedings of the National Academy of Sciences, 97(23).
van der Heide, T., & Poolman, B. (2000). Osmoregulated ABC-transport system of Lactococcus lactis senses water stress via changes in the physical state of the membrane. Proceedings of the National Academy of Sciences of the United States of America, 97(13), 7102 - 7106. https://doi.org/10.1073/pnas.97.13.7102
Poolman, B., & Heide, T. V. D. (2000). Osmoregulated ABC-Transporter Senses Water Stress via Changes in the Physical State of the Membrane. Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology, 126.
Gunnewijk, M. G. W., & Poolman, B. (2000). Phosphorylation state of HPr determines the level of expression and the extent of phosphorylation of the lactose transport protein of Streptococcus thermophilus. The Journal of Biological Chemistry, 275(44), 34073 - 34079. https://doi.org/10.1074/jbc.M003512200
Friesen, R. H. E., Poolman, B., & Knol, J. (2000). Quaternary structure of the lactose transport protein of Streptococcus thermophilus in the detergent-solubilized and membrane-reconstituted state. The Journal of Biological Chemistry, 275(43), 33527 - 33535. https://doi.org/10.1074/jbc.M004066200
Friesen, R. H. E., Poolman, B., & Knol, J. (2000). Quaternary structure of the lactose transport protein of Streptococcus thermophilus in the detergent-solubilized and membrane-reconstituted state (vol 275, pg 33527, 2000). The Journal of Biological Chemistry, 275(51), 40658 - 40658.
Spooner, P. J. R., Friesen, R. H. E., Poolman, B., Watts, A., & Knol, J. (2000). Rotational mobility and orientational stability of a transport protein in lipid membranes. Biophysical Journal, 79(2), 756 - 766. https://doi.org/10.1016/S0006-3495(00)76333-8
Picon, A., Kunji, E. R. S., Lanfermeijer, F. C., Konings, W. N., & Poolman, B. (2000). Specificity mutants of the binding protein of the oligopeptide transport system of Lactococcus lactis. Journal of Bacteriology, 182(6), 1600 - 1608. https://doi.org/10.1128/JB.182.6.1600-1608.2000
Ward, A., Sanderson, N. M., O'Reilly, J., Rutherford, N. G., Poolman, B., & Henderson, P. F. J. (2000). The amplified expression, identification, putrification, assay and properties of his-tagged bacterial membrane transport proteins. In Membrane transport: a practical appraoch (pp. 141 - 166). (Membrane transport: a practical appraoch). Oxford University Press.
Krijgsveld, J., Zaat, S. A. J., Meeldijk, J., van Veelen, P. A., Fang, G., Poolman, B., Brandt, E., Ehlert, J. E., Kuijpers, A. J., Engbers, G. H. M., Feijen, J., & Dankert, J. (2000). Thrombocidins, microbicidal proteins from human flood platelets, are C-terminal deletion products of CXC chemokines. The Journal of Biological Chemistry, 275(27), 20374 - 20381. https://doi.org/10.1074/jbc.275.27.20374

1999

Poolman, B., & Knol, J. (1999). Amplified expression and membrane reconstitution of transport proteins. Biochemical Society Transactions, 27, 912 - 917.
Lanfermeijer, F. C., Picon, A., Konings, W. N., & Poolman, B. (1999). Kinetics and consequences of binding of nona- and dodecapeptides to the oligopeptide binding protein (OppA) of Lactococcus lactis. Biochemistry, 38(44), 14440 - 14450. https://doi.org/10.1021/bi9914715
Fang, G., Friesen, R. H. E., Lanfermeijer, F. C., Hagting, A., Poolman, B., & Konings, W. N. (1999). Manipulation of activity and orientation of membrane- reconstituted di-tripeptide transport protein DtpT of Lactococcus lactis. Molecular Membrane Biology, 16(4), 297 - 304. https://doi.org/10.1080/096876899294517
Gunnewijk, M. G. W., Postma, P. W., & Poolman, B. (1999). Phosphorylation and Functional Properties of the IIA Domain of the Lactose Transport Protein of Streptococcus thermophilus. Journal of Bacteriology, 181(2), 632 - 641.
Poolman, B. (1999). Regulation of solute accumulation in bacteria and its physiological significance. In JK. BroomeSmith, S. Baumberg, CJ. Stirling, & FB. Ward (Eds.), TRANSPORT OF MOLECULES ACROSS MICROBIAL MEMBRANES (pp. 41-57). (SYMPOSIA OF THE SOCIETY FOR GENERAL MICROBIOLOGY; Vol. 58). Cambridge University Press.
Putman, M., van Veen, H. W., Poolman, B., & Konings, W. N. (1999). Restrictive use of detergents in the functional reconstitution of the secondary multidrug transporter LmrP. Biochemistry, 38(3), 1002 - 1008. https://doi.org/10.1021/bi981863w
Spooner, P. J. R., Veenhoff, L. M., Watts, A., & Poolman, B. (1999). Structural information on a membrane transport protein from nuclear magnetic resonance spectroscopy using sequence- selective nitroxide labeling. Biochemistry, 38(30), 9634 - 9639. https://doi.org/10.1021/bi990745l
Fristedt, U., van der Rest, M. E., Poolman, B., Konings, W. N., & Persson, B. L. (1999). Studies of cytochrome c oxidase-driven H+-coupled phosphate transport catalyzed by the Saccharomyces cerevisiae Pho84 permease in coreconstituted vesicles. Biochemistry, 38(48), 16010 - 16015. https://doi.org/10.1021/bi991545c
Veenhoff, L. M., & Poolman, B. (1999). Substrate recognition at the cytoplasmic and extracellular binding site of the lactose transport protein of Streptococcus thermophilus. The Journal of Biological Chemistry, 274(47), 33244 - 33250. https://doi.org/10.1074/jbc.274.47.33244
Veenhof, L. M., Spooner, P. J. R., Watts, A., & Poolman, B. (1999). Towards the localisation and characterisation of the ligand building sites of the lactose transport protein of Streptococcus thermophilus. In NATO ASI Molecular mechanisms of signalling and membrane transport

1998

Nakajima, H., Kunji, E. R. S., Poolman, B., & Konings, W. N. (1998). Amino acid transport in Lactobacillus helveticus. FEMS Microbiology Letters, 158(2), 249 - 253. https://doi.org/10.1111/j.1574-6968.1998.tb12828.x
Lolkema, J. S., Poolman, B., & Konings, W. N. (1998). Bacterial solute uptake and efflux systems. Current Opinion in Microbiology, 1(2), 248 - 253. https://doi.org/10.1016/S1369-5274(98)80018-0
Brondijk, T. H. C., van der Rest, M. E., Pluim, D., de Vries, Y., Stingl, K., Poolman, B., & Konings, W. N. (1998). Catabolite inactivation of wild-type and mutant maltose transport proteins in Saccaromyces cerevisiae. The Journal of Biological Chemistry, 273(25), 15352 - 15357. https://doi.org/10.1074/jbc.273.25.15352
Knol, J., Sjollema, K. A., & Poolman, B. (1998). Detergent-Mediated Reconstitution of Membrane Proteins. Biochemistry, 37(46), 16410 - 16415. https://doi.org/10.1021/bi981596u
Detmers, F. J. M., Kunji, E. R. S., Lanfermeijer, F. C., Poolman, B., & Konings, W. N. (1998). Kinetics and specificity of peptide uptake by the oligopeptide transport system of Lactococcus lactis. Biochemistry, 37(47), 16671 - 16679. https://doi.org/10.1021/bi981712t
Glaasker, E., Heuberger, E. H. M. L., Konings, W. N., & Poolman, B. (1998). Mechanism of Osmotic Activation of the Quaternary Ammonium Compound Transporter (QacT) of Lactobacillus plantarum. Journal of Bacteriology, 180(21), 5540 - 5546.
Glaasker, E., Tjan, F. S. B., ter Steeg, P. F., Konings, W. N., & Poolman, B. (1998). Physiological Response of Lactobacillus plantarum to Salt and Nonelectrolyte Stress. Journal of Bacteriology, 180(17), 4718 - 4723.
Kunji, E. R. S., Fang, G., Jeronimus-Stratingh, C. M., Bruins, A. P., Poolman, B., & Konings, W. N. (1998). Reconstruction of the proteolytic pathway for use of ß-casein by Lactococcus lactis. Molecular Microbiology, 27(6), 1107 - 1118. https://doi.org/10.1046/j.1365-2958.1998.00769.x
Poolman, B., & Glaasker, E. (1998). Regulation of compatible solute accumulation in bacteria. Molecular Microbiology, 29(2), 397 - 407. https://doi.org/10.1046/j.1365-2958.1998.00875.x

1997

Tolner, B., Poolman, B., & Konings, W. N. (1997). Adaptation of microorganisms and their transport systems to high temperatures. Comparative Biochemistry and Physiology A-Physiology, 118(3), 423-428. https://doi.org/10.1016/S0300-9629(97)00003-0
Hagting, A., Hasemeier, B., Streutker, M. R., Fang, G., Poolman, B., & Konings, W. N. (1997). Amplified expression, purification and functional reconstitution of the dipeptide and tripeptide transport protein of Lactococcus lactis. European Journal of Biochemistry, 247(2), 581-587. https://doi.org/10.1111/j.1432-1033.1997.00581.x
Verheul, A., Glaasker, E., Poolman, B., & Abee, T. (1997). Betaine and L-carnitine transport by Listeria monocytogenes Scott A in response to osmotic signals. Journal of Bacteriology, 179(22), 6979-6985.
Nakajima, H., Hagting, A., Kunji, E. R. S., Poolman, B., & Konings, W. N. (1997). Cloning and Functional Expression in Escherichia coli of the Gene Encoding the Di- and Tripeptide Transport Protein of Lactobacillus helveticus. Biochemistry, 36(22).
Nakajima, H., Hagting, A., Kunji, E. R. S., Poolman, B., & Konings, W. N. (1997). Cloning and functional expression in Escherichia coli of the gene encoding the di- and tripeptide transport protein of Lactobacillus helveticus. Applied and environmental microbiology, 63(6), 2213-2217.
Bolhuis, H., van Veen, H. W., Poolman, B., Driessen, A. J. M., & Konings, W. N. (1997). Mechanisms of multidrug transporters. FEMS Microbiology Reviews, 21(1), 55-84.
Bolhuis, H., Veen, H. W. V., Poolman, B., Driessen, A. J. M., & Konings, W. N. (1997). Mechanisms of multidrug transporters. Antonie van Leeuwenhoek, 71(1).
Hagting, A., van der Velde, T., Poolman, B., & Konings, W. N. (1997). Membrane topology of the di- an dtripeptide transport protein of Lactococcus lactis. Biochemistry, 22, 6777 - 6785.
Hagting, A., van de Velde, J., Poolman, B., & Konings, W. N. (1997). Membrane topology of the di- and tripeptide transport protein of Lactococcus lactis. Biochemistry, 36(22), 6777-6785. https://doi.org/10.1021/bi963068t
Poolman, B. (1997). Regulation of carbon metabolism in bacteria. In K. W. A. Wirtz (Ed.), Molecular mechanisms of signalling and membrane transport (pp. 319 - 330). Springer.
Poolman, B., Gunnewijk, M. G. W., Postma, P. W., & Veenhoff, L. M. (1997). Structure-function relationships in the lactose transport protein of Streptococcus thermophilus. The FASEB Journal, 11(9), 1321.
Konings, W. N., Lolkema, J. S., Bolhuis, H., van Veen, H. W., Poolman, B., & Driessen, A. J. M. (1997). The role of transport processes in survival of lactic acid bacteria. Antonie van Leeuwenhoek, 71, 117 - 128.
Konings, W. N., Lolkema, J. S., Bolhuis, H., van Veen, H. W., Poolman, B., & Driessen, A. J. M. (1997). The role of transport processes in survival of lactic acid bacteria. Energy transduction and multidrug resistance. Antonie Van Leeuwenhoek: International Journal of General and Molecular Microbiology, 71(1-2), 117-128. https://doi.org/10.1023/A:1000143525601
Marciset, O., Jeronimus-Stratingh, C. M., Mollet, B., & Poolman, B. (1997). Thermophilin 13, a nontypical antilisterial poration complex bacteriocin, that functions without a receptor. The Journal of Biological Chemistry, 272(22), 14277-14284. https://doi.org/10.1074/jbc.272.22.14277
Veenhoff, L. M., & Poolman, B. (1997). Unidirectional reconstitution of a secondary transport protein. The FASEB Journal, 11(9), 1322.

1996

Poolman, B., Knol, J., van der Does, C., Liang, W. J., Henderson, P. J. F., Leblanc, G., Pourcher, T., & MusVeteau, I. (1996). Cation and sugar selectivity determinants in a novel family of transport proteins. Molecular Microbiology, 19(5), 911-922. https://doi.org/10.1046/j.1365-2958.1996.397949.x
Bolhuis, H., van Veen, H. W., Brands, J. R., Putman, M., Poolman, B., Driessen, A. J. M., & Konings, W. N. (1996). Energetics and mechanism of drug transport mediated by the lactococcal multidrug transporter LmrP. The Journal of Biological Chemistry, 271(39), 24123-24128. https://doi.org/10.1074/jbc.271.39.24123
Kunji, E. R. S., Mierau, I., Poolman, B., Konings, W. N., Venema, G., & Kok, J. (1996). Fate of peptides in peptidase mutants of Lactococcus lactis. Molecular Microbiology, 21(1), 123 - 131. https://doi.org/10.1046/j.1365-2958.1996.6231339.x
Glaasker, E., Konings, W. N., & Poolman, B. (1996). Glycine betaine fluxes in Lactobacillus plantarum during osmostasis and hyper- and hypo-osmotic shock. The Journal of Biological Chemistry, 271(17), 10060 - 10065. https://doi.org/10.1074/jbc.271.17.10060
Salema, M., Capucho, N. V., Poolman, B., SanRamao, MV., & Dias, MCL. (1996). In vitro reassembly of the malolactic fermentation pathway of Leuconostoc oenos (Oenococcus oeni). Journal of Bacteriology, 178(18), 5537 - 5539.
Bolhuis, H., van Veen, H. W., Molenaar, D., Poolman, B., Driessen, A. J. M., & Konings, W. N. (1996). Multidrug resistance in Lactococcus lactis: Evidence for ATP-dependent drug extrusion from the inner leaflet of the cytoplasmic membrane. EMBO Journal, 15(16), 4239-4245.
Veen, H. W. V., Venema, K., Bolhuis, H., Oussenko, I., Kok, J., Poolman, B., Driessen, A. J. M., & Konings, W. N. (1996). Multidrug resistance mediated by a bacterial homolog of the human multidrug transporter MDR1. Proceedings of the National Academy of Sciences of the United States of America, 93(20), 10668 - 10672. https://doi.org/10.1073/pnas.93.20.10668
Mierau, I., Kunji, E. R. S., Leenhouts, K. J., Hellendoorn, M. A., Haandrikman, A. J., Poolman, B., Konings, W. N., Venema, G., & Kok, J. (1996). Multiple-peptidase mutants of Lactococcus lactis are severely impaired in their ability to grow in milk. Journal of Bacteriology, 178(10), 2794 - 2803.
Glaasker, E., Konings, W. N., & Poolman, B. (1996). Osmotic regulation of intracellular solute pools in Lactobacillus plantarum. Journal of Bacteriology, 178(3), 575 - 582.
Poolman, B. (1996). Secondary transporters and metabolic energy generation in bacteria. In J. S. Lolkema, H. R. Kaback, & W. N. Konings (Eds.), Handbook of Biological Physics (pp. 229 - 260). Elsevier Applied Science.
Glaasker, E., Konings, W. N., & Poolman, B. (1996). The application of pH-sensitive fluorescent dyes in lactic acid bacteria reveals distinct extrusion systems for unmodified and conjugated dyes. Molecular Membrane Biology, 13(3), 173 - 181. https://doi.org/10.3109/09687689609160594
Kunji, E. R. S., Mierau, I., Hagting, A., Poolman, B., & Konings, W. N. (1996). The proteolytic systems of lactic acid bacteria. Antonie Van Leeuwenhoek: International Journal of General and Molecular Microbiology, 70(2-4), 187 - 221.
Veenhoff, L., Liang, W-J., Henderson, P. J. F., Leblanc, G., & Poolman, B. (1996). Unidirectional reconstitution into detergent-destabilized liposomes of the purified lactose transport system of Streptococcus thermophilus. The Journal of Biological Chemistry, 271(26), 15358 - 15366. https://doi.org/10.1074/jbc.271.26.15358
Poolman, B., Knol, J., Veenhoff, L., & Sulter, G. (1996). Unidirectional reconstitution of a secondary transport protein. Progress in Biophysics & Molecular Biology, 65, PC513-PC513.

1995

Tolner, B., Ubbink-Kok, T., Poolman, B., & Konings, W. N. (1995). Cation-selectivity of the l-glutamate transporters of Escherichia coli, Bacillus stearothermophilus and Bacillus caldotenax - dependence on the environment in which the proteins are expressed: dependence on the environment in which the proteins are expressed. Molecular Microbiology, 18(1), 123-133. https://doi.org/10.1111/j.1365-2958.1995.mmi_18010123.x
Tolner, B., Ubbink-Kok, T., Poolman, B., & Konings, W. N. (1995). Characterization of the proton/glutamate symport protein of Bacillus subtilis and its functional expression in Escherichia coli. Journal of Bacteriology, 177(10), 2863-2869.
Poolman, B., & Lolkema, J. S. (1995). Kinetic-analysis of lactose and proton coupling in glu(379) mutants of the lactose transport protein of streptococcus thermophilus. The Journal of Biological Chemistry, 270(22), 12995-13003. https://doi.org/10.1074/jbc.270.22.12995
Sikkema, J., de Bont, J. A. M., & Poolman, B. (1995). Mechanisms of membrane toxcity of hydrocarbons. Microbiology and Molecular Biology Reviews, 59(2), 201-222. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC239360/
Speelmans, G., Poolman, B., & Konings, W. N. (1995). NA+ AS COUPLING ION IN ENERGY TRANSDUCTION IN EXTREMOPHILIC BACTERIA AND ARCHAEA. World Journal of Microbiology & Biotechnology, 11(1), 58 - 70. https://doi.org/10.1007/bf00339136
van der Rest, M. E., de Vries, Y., Poolman, B., & Konings, W. N. (1995). Overexpression of Mal61p in Saccharomyces cerevisiae and Characterization of Maltose Transport in Artificial Membranes. Journal of Bacteriology, 177(19), 5440-5446.
Mierau, I., Kunji, E. R. S., Venema, G., Poolman, B., & Kok, J. (1995). Peptidases and growth of Lactococcus lactis in milk. Lait, 76(1-2), 25 - 34. https://doi.org/10.1051/lait:19961-23
Poolman, B., Mollet, B., Nieuwenhuis, B., & Sulter, G. (1995). Regulation of bacterial sugar-H+ symport by phosphoenolpyruvate-dependent enzyme I/HPr-mediated phosphorylation. Proceedings of the National Academy of Sciences of the United States of America, 92(3), 778-782.
Lolkema, J. S., Poolman, B., & Konings, W. N. (1995). Role of Scalar Protons in Metabolic Energy Generation in Lactic Acid Bacteria. Journal of Bioenergetics and Biomembranes, 27(4), 467-473. https://doi.org/10.1007/BF02110009
Oosterhaven, K., Poolman, B., & Smid, E. J. (1995). S-CARVONE AS A NATURAL POTATO SPROUT INHIBITING, FUNGISTATIC AND BACTERIOSTATIC COMPOUND. Industrial Crops and Products, 4(1), 23 - 31. https://doi.org/10.1016/0926-6690(95)00007-Y
Foucaud, C., Kunji, E. R. S., Hagting, A., Richard, J., Konings, W. N., Desmazeaud, M., & Poolman, B. (1995). Specificity of Peptide Transport Systems in Lactococcus lactis: Evidence for a Third System Which Transports Hydrophobic Di- and Tripeptides. Journal of Bacteriology, 177(16), 4652-4657.
FOUCAUD, C., KUNJI, ERS., HAGTING, A., RICHARD, J., KONINGS, WN., DESMAZEAUD, M., & POOLMAN, B. (1995). SPECIFICITY OF PEPTIDE-TRANSPORT SYSTEMS IN LACTOCOCCUS-LACTIS - EVIDENCE FOR A 3RD SYSTEM WHICH TRANSPORTS HYDROPHOBIC DIPEPTIDES AND TRIPEPTIDES. Journal of Bacteriology, 177(16), 4652-4657.
Konings, W. N., Lolkema, J. S., & Poolman, B. (1995). THE GENERATION OF METABOLIC ENERGY BY SOLUTE TRANSPORT. Archives of Microbiology, 164(4), 235 - 242. https://doi.org/10.1007/s002030050260
Peekhaus, N., Tolner, B., Poolman, B., & Kramer, R. (1995). The glutamate uptake regulatory protein (grp) of zymamonas mobilis and its relation to the global regulator LRP of Escherichia-coli. Journal of Bacteriology, 177(17), 5140-5147.
Bolhuis, H., Poelarends, G. J., van Veen, H. W., Poolman, B., Driessen, A. J. M., & Konings, W. N. (1995). The Lactococcal lmrP Gene Encodes a Proton Motive Forcedependent Drug Transporter. The Journal of Biological Chemistry, 270(44), 26092 - 26098. https://doi.org/10.1074/jbc.270.44.26092
VANDERREST, ME., KAMMINGA, AH., NAKANO, A., ANRAKU, Y., POOLMAN, B., & KONINGS, WN. (1995). The Plasma Membrane of Saccharomyces cerevisiae: Structure, Function, and Biogenesis. Microbiological Reviews, 59(2), 304-322.
Poolman, B., Kunji, E. R. S., Hagting, A., Juillard, V., & Konings, W. N. (1995). THE PROTEOLYTIC PATHWAY OF LACTOCOCCUS-LACTIS. Journal of Applied Bacteriology, 79, S65-S75.
Kunji, E. R. S., Hagting, A., de Vries, C. J., Juillard, V., Haandrikman, A. J., Poolman, B., & Konings, W. N. (1995). Transport of β-Casein-derived Peptides by the Oligopeptide Transport System Is a Crucial Step in the Proteolytic Pathway of Lactococcus lactis. The Journal of Biological Chemistry, 270(4), 1569-1574. https://doi.org/10.1074/jbc.270.4.1569
Lolkema, J. S., & Poolman, B. (1995). Uncoupling in Secondary Transport Proteins. A Mechanistic Explanation for Mutants of lac Permease with an Uncoupled Phenotype. The Journal of Biological Chemistry, 270(21), 12670-12676. https://doi.org/10.1074/jbc.270.21.12670

1994

SIKKEMA, J., DEBONT, JAM., & POOLMAN, B. (1994). Interactions of Cyclic Hydrocarbons with Biological Membranes. The Journal of Biological Chemistry, 269(11), 8022-8028.
NEUBAUER, H., GLAASKER, E., HAMMES, WP., POOLMAN, B., & KONINGS, WN. (1994). Mechanism of Maltose Uptake and Glucose Excretion in Lactobacillus sanfrancisco. Journal of Bacteriology, 176(10), 3007-3012.
BOLHUIS, H., MOLENAAR, D., POELARENDS, G., VANVEEN, HW., POOLMAN, B., DRIESSEN, AJM., & KONINGS, WN. (1994). Proton Motive Force-Driven and ATP-Dependent Drug Extrusion Systems in Multidrug-Resistant Lactococcus lactis. Journal of Bacteriology, 176(22), 6957-6964.
Konings, W. N., Poolman, B., & van Veen, H. W. (1994). Solute transport and energy transduction in bacteria. Antonie Van Leeuwenhoek: International Journal of General and Molecular Microbiology, 65(4), 369-380. https://doi.org/10.1007/BF00872220
Hagting, A., Kunji, E. R. S., Leenhouts, C. J., Poolman, B., & Konings, W. N. (1994). The di- and tripeptide transport protein of Lactococcus lactis. The Journal of Biological Chemistry, 15, 11391 - 11398.
HAGTING, A., KUNJI, ERS., LEENHOUTS, KJ., POOLMAN, B., & KONINGS, WN. (1994). The Di- and Tripeptide Transport Protein of Lactococcus lactis. A New Type of Bacterial Peptide Transporter. The Journal of Biological Chemistry, 269(15), 11391-11399.
SPEELMANS, G., POOLMAN, B., ABEE, T., & KONINGS, WN. (1994). The F- or V-Type Na+-ATPase of the Thermophilic Bacterium Clostridium fervidus. Journal of Bacteriology, 176(16), 5160-5162.
RAMOS, A., POOLMAN, B., SANTOS, H., LOLKEMA, JS., & KONINGS, WN. (1994). Uniport of Anionic Citrate and Proton Consumption in Citrate Metabolism Generates a Proton Motive Force in Leuconostoc oenos. Journal of Bacteriology, 176(16), 4899-4905.
SALEMA, M., POOLMAN, B., LOLKEMA, JS., DIAS, MCL., & KONINGS, WN. (1994). Uniport of monoanionic L-malate in membrane vesicles from Leuconostoc oenos. European Journal of Biochemistry, 225(1), 289-295. https://doi.org/10.1111/j.1432-1033.1994.00289.x

1993

SPEELMANS, G., POOLMAN, B., & KONINGS, WN. (1993). Amino Acid Transport in the Thermophilic Anaerobe Clostridium fervidus Is Driven by an Electrochemical Sodium Gradient. Journal of Bacteriology, 175(7), 2060-2066.
SPEELMANS, G., HILLENGA, D., POOLMAN, B., & KONINGS, WN. (1993). Application of thermostable reaction centers from Chloroflexus aurantiacus as a protonmotive force generating system. Biochimica et biophysica acta, 1142(3), 269-276. https://doi.org/10.1016/0005-2728(93)90155-9
POOLMAN, B. (1993). BIOCHEMISTRY AND MOLECULAR-BIOLOGY OF GALACTOSIDE TRANSPORT AND METABOLISM IN LACTIC-ACID BACTERIA. Lait, 73(2), 87-96.
Mollet, B., Poolman, B., Marciset, O., & Delley, M. (1993). Directed Genomic Integration, Gene Replacement, and Integrative Gene Expression in Streptococcus thermophilus. Journal of Bacteriology, 175(14), 4315-4324.
KUNJI, ERS., SMID, EJ., PLAPP, R., POOLMAN, B., & KONINGS, WN. (1993). Di-Tripeptides and Oligopeptides Are Taken Up via Distinct Transport Mechanisms in Lactococcus lactis. Journal of Bacteriology, 175(7), 2052-2059.
Venema, G., & Poolman, B. (1993). Editorial. FEMS Microbiology Reviews, 12, 1.
Poolman, B. (1993). Energy transduction in lactic acid bacteria. FEMS Microbiology Reviews, 12(1-3), 125-148. https://doi.org/10.1111/j.1574-6976.1993.tb00015.x
SPEELMANS, G., POOLMAN, B., ABEE, T., & KONINGS, WN. (1993). Energy transduction in the thermophilic anaerobic bacterium Clostridium fervidus is exclusively coupled to sodium ions. Proceedings of the National Academy of Sciences, 90(17), 7975-7979. https://doi.org/10.1073/pnas.90.17.7975
TYNKKYNEN, S., BUIST, G., KUNJI, E., KOK, J., POOLMAN, B., VENEMA, G., & HAANDRIKMAN, A. (1993). Genetic and Biochemical Characterization of the Oligopeptide Transport System of Lactococcus lactis. Journal of Bacteriology, 175(23), 7523-7532.
DEVOS, WM., VELD, JHJHI., & POOLMAN, B. (1993). PAPERS PRESENTED AT THE 4TH SYMPOSIUM ON LACTIC-ACID BACTERIA - GENETICS, METABOLISM AND APPLICATIONS NOORDWIJKERHOUT, THE NETHERLANDS, 5-9 SEPTEMBER 1993. FEMS Microbiology Reviews, 12(1-3), 1-1.
Kunji, E. R. S., Ubbink, T., Matin, A., Poolman, B., & Konings, W. N. (1993). Physiological responses of Lactococcus lactis ML3 to alternating conditions of growth and starvation. Archives of Microbiology, 159(4), 372-379. https://doi.org/10.1007/BF00290920
TAN, PST., POOLMAN, B., & KONINGS, WN. (1993). PROTEOLYTIC-ENZYMES OF LACTOCOCCUS-LACTIS. Journal of Dairy Research, 60(2), 269-286.
LAAN, H., BOLHUIS, H., POOLMAN, B., ABEE, T., & KONINGS, WN. (1993). REGULATION OF PROTEINASE SYNTHESIS IN LACTOCOCCUS-LACTIS. Acta biotechnologica, 13(2), 95-101.
POOLMAN, B., & KONINGS, WN. (1993). SECONDARY SOLUTE TRANSPORT IN BACTERIA. Biochimica et biophysica acta, 1183(1), 5-39. https://doi.org/10.1016/0005-2728(93)90003-X
LOCHER, HH., POOLMAN, B., COOK, AM., & KONINGS, WN. (1993). Uptake of 4-Toluene Sulfonate by Comamonas testosteroni T-2. Journal of Bacteriology, 175(4), 1075-1080.

1992

Konings, W. N., Poolman, B., & Driessen, A. J. M. (1992). Can the excretion of metabolites by bacteria be manipulated? FEMS Microbiology Reviews, 88(2), 93-108. https://doi.org/10.1111/j.1574-6968.1992.tb04959.x
TOLNER, B., POOLMAN, B., & KONINGS, WN. (1992). Characterization and functional expression in Escherichia coli of the sodium/proton/glutamate symport proteins of Bacillus stearothermophilus and Bacillus caldotenax. Molecular Microbiology, 6(19), 2845-2856. https://doi.org/10.1111/j.1365-2958.1992.tb01464.x
TAN, PST., VANALENBOERRIGTER, IJ., POOLMAN, B., SIEZEN, RJ., DEVOS, WM., & KONINGS, WN. (1992). Characterization of the Lactococcus lactis pepN gene encoding an aminopeptidase homologous to mammalian aminopeptidase N. FEBS Letters, 306(1), 9-16. https://doi.org/10.1016/0014-5793(92)80827-4
SIKKEMA, J., POOLMAN, B., KONINGS, WN., & DEBONT, JAM. (1992). Effects of the Membrane Action of Tetralin on the Functional and Structural Properties of Artificial and Bacterial Membranes. Journal of Bacteriology, 174(9), 2986-2992.
FOUCAUD, C., & POOLMAN, B. (1992). Lactose Transport System of Streptococcus thermophilus. Functional Reconstitution of the Protein and Characterization of the Kinetic Mechanism of Transport. The Journal of Biological Chemistry, 267(31), 22087-22094.
Poolman, B., Modderman, R., & Reizer, J. (1992). Lactose Transport System of Streptococcus thermophilus. The Role of Histidine Residues. The Journal of Biological Chemistry, 267(13), 9150-9157.
TOLNER, B., POOLMAN, B., WALLACE, B., & KONINGS, WN. (1992). Revised Nucleotide Sequence of the gltP Gene, Which Encodes the Proton-Glutamate-Aspartate Transport Protein of Escherichia coli K-12. Journal of Bacteriology, 174(7), 2391-2393.
MOLENAAR, D., BOLHUIS, H., ABEE, T., POOLMAN, B., & KONINGS, WN. (1992). The Efflux of a Fluorescent Probe Is Catalyzed by an ATP-Driven Extrusion System in Lactococcus lactis. Journal of Bacteriology, 174(10), 3118-3124.

1991

WINTERS, DA., POOLMAN, B., HEMME, D., & KONINGS, WN. (1991). Branched-Chain Amino Acid Transport in Cytoplasmic Membranes of Leuconostoc mesenteroides subsp. dextranicum CNRZ 1273. Applied and environmental microbiology, 57(11), 3350-3354.
SMID, EJ., POOLMAN, B., & KONINGS, WN. (1991). CASEIN UTILIZATION BY LACTOCOCCI. Applied and environmental microbiology, 57(9), 2447-2452.
Poolman, B., Molenaar, D., Smid, E. J., Ubbink, T., Abee, T., Renault, P. P., & Konings, W. N. (1991). Malolactic Fermentation: Electrogenic Malate Uptake and Malate/Lactate Antiport Generate Metabolic Energy. Journal of Bacteriology, 173(19), 6030-6037.

1990

Poolman, B., Royer, T. J., Mainzer, S. E., & Schmidt, B. F. (1990). Carbohydrate Utilization in Streptococcus thermophilus: Characterization of the Genes for Aldose 1-Epimerase (Mutarotase) and UDPglucose 4-Epimerase. Journal of Bacteriology, 172, 4037-3047.
Poolman, B. (1990). Precursor/product antiport in bacteria. Molecular Microbiology, 4(10), 1629-1636. https://doi.org/10.1111/j.1365-2958.1990.tb00539.x
VENEMA, G., POOLMAN, B., & WOUTERS, JTM. (1990). SPECIAL ISSUE - PAPERS PRESENTED AT THE 3RD SYMPOSIUM ON LACTIC-ACID BACTERIA GENETICS, METABOLISM AND APPLICATIONS WAGENINGEN, THE NETHERLANDS, 17-21 SEPTEMBER 1990. FEMS Microbiology Reviews, 87(1-2), 1-1.

1989

Konings, W. N., Poolman, B., Driessen, A. J. M., & Maloney, P. C. (1989). Bioenergetics and solute transport in Lactococci. CRC Critical Reviews in Microbiology, 16(6), 419-476. https://doi.org/10.3109/10408418909104474
Poolman, B., Royer, T. J., Mainzer, S. E., & Schmidt, B. F. (1989). Lactose Transport System of Streptococcus thermophilus: a Hybrid Protein with Homology to the Melibiose Carrier and Enzyme III of Phosphoenolpyruvate-Dependent Phosphotransferase Systems. Journal of Bacteriology, 171, 244-253.

1988

Poolman, B., & Konings, W. N. (1988). Relation of Growth of Streptococcus lactis and Streptococcus cremoris to Amino Acid Transport. Journal of Bacteriology, 170(2), 700-707.

1987

Driessen, A. J. M., Poolman, B., Kiewiet, R., & Konings, W. N. (1987). Arginine transport in Streptococcus lactis is catalyzed by a cationic exchanger. Proceedings of the National Academy of Sciences, 84(17), 6093-6097. https://doi.org/10.1073/pnas.84.17.6093
Poolman, B., Smid, E. J., Veldkamp, H., & Konings, W. N. (1987). Bioenergetic Consequences of Lactose Starvation for Continuously Cultured Streptococcus cremoris. Journal of Bacteriology, 169(4), 1460-1468.
POOLMAN, B., BOSMAN, B., & KONINGS, WN. (1987). Control of Glycolysis by Glyceraldehyde-3-Phosphate Dehydrogenase in Streptococcus cremoris and Streptococcus lactis. Journal of Bacteriology, 169(12), 5887-5890.
POOLMAN, B., NIJSSEN, RMJ., & KONINGS, WN. (1987). Dependence of Streptococcus lactis Phosphate Transport on Internal Phosphate Concentration and Internal pH. Journal of Bacteriology, 169(12), 5373-5378.
Poolman, B. (1987). Energy transducing processes in growing and starving lactic acid streptococcci. s.n.
POOLMAN, B., SMID, EJ., & KONINGS, WN. (1987). Kinetic Properties of a Phosphate-Bond-Driven Glutamate-Glutamine Transport System in Streptococcus lactis and Streptococcus cremoris. Journal of Bacteriology, 169(6), 2755-2761.
POOLMAN, B., DRIESSEN, AJM., & KONINGS, WN. (1987). Regulation of Arginine-Ornithine Exchange and the Arginine Deiminase Pathway in Streptococcus lactis. Journal of Bacteriology, 169(12), 5597-5604.
POOLMAN, B., DRIESSEN, AJM., & KONINGS, WN. (1987). Regulation of Solute Transport in Streptococci by External and Internal pH Values. Microbiological Reviews, 51(4), 498-508.
POOLMAN, B., HELLINGWERF, KJ., & KONINGS, WN. (1987). Regulation of the Glutamate-Glutamine Transport System by Intracellular pH in Streptococcus lactis. Journal of Bacteriology, 169(5), 2272-2276.

1986

de Vrij, W., Poolman, B., Konings, W., & Azzi, A. (1986). Purification, enzymatic properties, and reconstitution of cytochrome-c oxidase from Bacillus subtilis. Methods in Enzymology, 126, 159-173.

1985

DEVRIJ, W., POOLMAN, B., AZZI, A., & KONINGS, WN. (1985). STRUCTURAL AND FUNCTIONAL-ASPECTS OF CYTOCHROME-C-OXIDASE FROM BACILLUS-SUBTILIS W 23. Antonie van Leeuwenhoek: Journal of Microbiology, 51(5-6), 573-574.
ELFERINK, MGL., HELLINGWERF, KJ., VANDIJL, JM., ROBILLARD, GT., POOLMAN, B., & KONINGS, WN. (1985). THE ROLE OF ELECTRON-TRANSFER AND DITHIOL-DISULFIDE INTERCHANGE IN SOLUTE TRANSPORT IN BACTERIA. Annals of the New York Academy of Sciences, 456, 361-374.

1984

Elferink, M. G. L., Hellingwerf, K. J., Belkum, M. J. V., Poolman, B., & Konings, W. N. (1984). Direct interaction between linear electron transfer chains and solute transport systems in bacteria. FEMS Microbiology Letters, 21(3), 293-298. https://doi.org/10.1111/j.1574-6968.1984.tb00324.x

1983

Poolman, B., Konings, W. N., & Robillard, G. T. (1983). The location of redox-sensitive groups in the carrier protein of proline at the outer and inner surface of the membrane in Escherichia coli. European Journal of Biochemistry, 135(1), 41-46. https://doi.org/10.1111/j.1432-1033.1983.tb07615.x
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