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About usMedical SciencesResearchDepartment of GeneticsResearch Lines
University Medical Center Groningen

Research lines in the Dept of Genetics, UMCG

   

Complex (multifactorial) diseases

Project leaders (PIs)

Cisca Wijmenga
Sebo Withoff
Sasha Zhernakova
Vinod Kumar
Iris Jonkers

Systems Genetics/Bioinformatics

  • Big data approaches to identifying environmental risk factors for disease
  • Factor analytic modeling of expression data and EQTL mapping
  • Using systems genetics to understand complex biological systems by integrating systems biology with genetics
  • Systems genetics of celiac disease, with a focus on non-coding regions of the genome
  • Integration of high-throughput expression and sequence data into the Oncology workstation (CTMM project)

See also www.systemsgenetics.nl

Lude Franke
Jingyuan Fu
Yang Li
Gerard te Meerman

5GPM: Five genes per minute

Whole-genome sequencing of critically ill newborns, more

Cleo van Diemen
Rolf Sijmons

Congenital diseases

Chromosome 6 research (a parent-driven project)
CHARGE syndrome
Phelan-McDermid syndrome
(22q13 deletion syndrome)

Conny van Ravenswaaij

EUROCAT - Epidemiological Surveillance of Congenital Anomalies
Eurolinkcat - establishing a linked European cohort of children with congenital anomalies

Hermien de Walle

Dystrophic epidermolysis bullosa (DEB) (more in Dutch, in English) Peter van de Akker
L1CAM Yvonne Vos

Oncogenetics

Clinical Genetics of Familial Cancer

Rolf Sijmons, Helga Westers, Klaas Kok

Renal Cell Cancer

Klaas Kok, Eva van den Berg

FaCD (Familial Cancer Database)

Rolf Sijmons

Neurogenetics

SpinoCerebellar Ataxia (SCA)

Dineke Verbeek

Genetic screening in children with epilepsy

Conny van Ravenswaaij, Patrick Rump, Yvonne Vos

Cardiogenetics

Chronic heart failure, Cardiac fibrosis, CHF subforms Peter van Tintelen
ARCV (Arrhythmogenic right ventricular cardiomyopathy) Jan Jongbloed
LVOTO (Left ventricular outflow tract obstructions) Mieke Kerstjens
DIDCARE (Dutch idiopathic dilated cardiomyopathy registry) Jan Jongbloed

ELSI (Ethics, legal, and social issues in clinical genetics)

The ELSI research programme aims to provide the evidence base for offering clinical genetic services to patients using new techniques and innovations more

Other ELSI research work, see Jeantine Lunshof

Irene van Langen

Last modified:26 March 2019 2.51 p.m.