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Ronald Mark Evans (1949, Los Angeles, USA)

Ronald Mark Evans
Ronald Mark Evans
  • Ronald Evans received his BA of Science and PhD from UCLA, Los Angeles, and his postdoctoral training at Rockefeller University, New York. He began his career as a faculty member at the Salk Institute for Biological Studies in La Jolla, California, and is also an Adjunct Professor in Biology, Biomedical Sciences and Neuroscience at the University of California, San Diego.
  • He is a Professor and Director of the Salk Institute’s Gene Expression Laboratory, as well as an Investigator at the Howard Hughes Medical Institute.
  • He is known worldwide for his work on hormones, especially for the discovery of a large family of molecules that respond to various hormones, leading to new treatments of metabolic diseases and cancer as well as influencing our daily health.
  • Recent publications:
    • Insights into negative regulation by the glucocorticoid receptor from genome-wide profiling of inflammatory cistromes (2013)
    • A Role for Vitamin D in liver disease and cancer (2013)
    • A PPARĪ³-FGF1 axis is required for adaptive adipose remodelling and metabolic homeostasis (2012)
  • He was named the March of Dimes Chair in Molecular and Developmental Biology at the Salk Institute in 1998 and has received many awards and prizes, including the March of Dimes Prize in Developmental Biology (2003), the Harvey Prize (2006), the Albert Lasker Award (2004) and the Wolf Prize in Medicine (2012).
  • Ronald Evans was nominated for the honorary doctorate by the Faculty of Medical Sciences to honour his breakthrough discovery of the role of hormones in the regulation of metabolism.

For over 40 years Ronald (Ron) Evans has studied how hormones behave in normal physiology and during a disease. His great moment came when he discovered a family of molecules, called nuclear receptors, which are activated by certain hormones and vitamins. These hormones help control the way the body processes for instance sugar, salt, calcium and fat.

The discovery of this missing link in the regulation of metabolism leads to new, promising treatments of metabolic diseases, cancer and asthma. In addition, this knowledge teaches us more about health problems like obesity and diabetes and may well lead to a significant improvement of health in general, especially in societies where rich and fatty foods are so popular.

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Last modified:21 September 2018 11.14 a.m.