Research in the Onck group aims at understanding the micromechanical and functional behavior of (biological) materials based on an accurate description of the underlying (bio-) physical mechanisms. Computational techniques (e.g. molecular dynamics, finite element methods, finite volume approaches, solid-fluid interaction techniques) are being used to explicitly account for the physical mechanisms at the relevant length scales.
The research can be grouped in three main topics:
In this work we study fundamental processes in the cell in order to elucidate the biophysical mechanisms that are responsible for transport of biomolecules through the nuclear pore complex, the transmission of mechanical forces through the cytoskeleton, protein aggregation in neurodegenerative diseases and membrane fusion by studying the conformational dynamics of surface proteins. For more details, follow this link.
Metallic and graphene (nano-)foams have excellent properties per unit weight. In addition, they can undergo dimensional changes when a potential difference is applied in an electrochemical environment or when a magnetic field is applied. Here we combine atomistic and continuum techniques to link the porous (nano-)structure to their functional and mechanical properties. For more details, follow this link.
This work aims at understanding and designing smart and responsive materials by developing computational models (molecular dynamics, solid-fluid interaction techniques and finite-element models) for application in, e.g., NEMS/MEMS, microfluidic and lab-on-chip applications. Emphasis is on magneto-, electro- and photomechanical interactions. For more details, follow this link.
|Last modified:||18 October 2017 10.09 a.m.|