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Happy faces and other rewards

Different perspectives on a bias away from positive and toward negative information as an underlying mechanism of depression
PhD ceremony:dr. C. (Charlotte) Vrijen
When:May 13, 2019
Start:16:15
Supervisors:prof. dr. A.J. (Tineke) Oldehinkel, dr. C.A. (Catharina) Hartman, prof. dr. P. (Peter) de Jonge
Where:Academy building RUG
Faculty:Medical Sciences / UMCG
Happy faces and other rewards

Happy faces and other rewards

People generally show strong responses to positive or rewarding experiences, for example, winning a prize or seeing someone smile. However, not all people respond the same to positive information; some people show weaker responses to positive information and stronger responses to negative information. These people show a so-called low positive bias. In 7 different studies, I investigated low positive bias in adolescence as an underlying mechanism of depression with different instruments and from different perspectives, combining longitudinal data collected every 2-3 years with more fine-grained momentary assessments collected three times per day, data from laboratory tasks and salivary biomarkers.

I studied whether a low bias toward positive information in adolescence predicted later onset of depression and also investigated the daily life implications of a low positive bias. From a treatment perspective, I studied whether tailored lifestyle advice and an extreme free-fall experience (tandem skydive) could be effective in increasing pleasure and implicit positive bias in young adults suffering from loss of pleasure.

One of the main findings reported in my dissertation is that low positive bias during early and mid-adolescence predicted onset of depression later in life and may mark vulnerability for depression. In daily life, young adults with a high positive bias sustained their positive emotions and experiences more strongly over time than those with a low happy bias. I further found evidence that tailored lifestyle advice increased self-reported daily pleasure, but no evidence that this intervention also increased positive bias.