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Franke, Prof. Lude

Lude Franke
Lude Franke

Lude Franke is Associate Professor at the Genetics Department of the University of Groningen/University Medical Centre Groningen and Head of Research and Education in the Dept. of Genetics, UMCG. He is a statistical geneticist, working on analyzing data on the genetics of complex and autoimmune diseases (e.g. celiac disease). He has been awarded an ERC Starting grant (2014), NWO VIDI grant (2014), NWO VENI grant (2009) and a Horizon Grant (2009) to work on identifying molecular effects due to disease-causing mutations.

In his spare time he is also a graphic designer (see his PhD thesis design ). This chance combination of skills can sometimes make life as a genetics researcher a bit easier: if you can explain your research visually, more people can understand what you are doing. Lude Franke is one of the founding members of the Young Academy Groningen and has also been appointed member of De Jonge Akademie (National Young Academy).

In 2021 Franke was awarded a Vici grant. Many diseases have a genetic basis, but cancer is often caused by mutations that arise during life, whereas other diseases are caused by genetic differences that are inherited from parents. Frankes project uses gene networks to test whether a unifying principle exists that links these different types of mutations.

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Publications

2021

BIOS Consortium, Pellegrino-Coppola, D., Claringbould, A., Stutvoet, M., Boomsma, D. I., Ikram, M. A., Slagboom, P. E., Westra, H-J., & Franke, L. (2021). Correction for both common and rare cell types in blood is important to identify genes that correlate with age. BMC Genomics, 22(1), [184]. https://doi.org/10.1186/s12864-020-07344-w
BIOS Consortium, van Dongen, J., Hagenbeek, F. A., Suderman, M., Roetman, P. J., Sugden, K., Chiocchetti, A. G., Ismail, K., Mulder, R. H., Hafferty, J. D., Adams, M. J., Walker, R. M., Morris, S. W., Lahti, J., Küpers, L. K., Escaramis, G., Alemany, S., Jan Bonder, M., Meijer, M., ... Franke, L. (2021). DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan. Molecular Psychiatry. https://doi.org/10.1038/s41380-020-00987-x
Peters, V., Tigchelaar-Feenstra, E. F., Imhann, F., Dekens, J. A. M., Swertz, M. A., Franke, L. H., Wijmenga, C., Weersma, R. K., Alizadeh, B. Z., Dijkstra, G., & Campmans-Kuijpers, M. J. E. (2021). Habitual dietary intake of IBD patients differs from population controls: a case-control study. European Journal of Nutrition. https://doi.org/10.1007/s00394-020-02250-z
Warmerdam, R., Lanting, P., Deelen, P., & Franke, L. (2021). Idéfix: identifying accidental sample mix-ups in biobanks using polygenic scores. Manuscript submitted for publication. https://doi.org/10.1101/2021.03.12.435080
Matzaraki, V., Le, K. T. T., Jaeger, M., Aguirre-Gamboa, R., Johnson, M. D., Sanna, S., Rosati, D., Franke, L., Zhernakova, A., Fu, J., Withoff, S., Jonkers, I., Li, Y., Joosten, L. A. B., Netea, M. G., Wijmenga, C., & Kumar, V. (2021). Inflammatory Protein Profiles in Plasma of Candidaemia Patients and the Contribution of Host Genetics to Their Variability. Frontiers in Immunology, 12, [662171]. https://doi.org/10.3389/fimmu.2021.662171
Chu, X., Jaeger, M., Beumer, J., Bakker, O. B., Aguirre-Gamboa, R., Oosting, M., Smeekens, S. P., Moorlag, S., Mourits, V. P., Koeken, V. A. C. M., de Bree, C., Jansen, T., Mathews, I. T., Dao, K., Najhawan, M., Watrous, J. D., Joosten, I., Sharma, S., Koenen, H. J. P. M., ... Li, Y. (2021). Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease. Genome Biology, 22(1), [198]. https://doi.org/10.1186/s13059-021-02413-z
MiBioGen Consortium Initiative, Kurilshikov, A., Medina-Gomez, C., Bacigalupe, R., Radjabzadeh, D., Wang, J., Demirkan, A., Le Roy, C. I., Raygoza Garay, J. A., Finnicum, C. T., Liu, X., Zhernakova, D. V., Bonder, M. J., Hansen, T. H., Frost, F., Ruehlemann, M. C., Turpin, W., Moon, J-Y., Kim, H-N., ... Zhernakova, A. (2021). Large-scale association analyses identify host factors influencing human gut microbiome composition. Nature Genetics, 156-165. https://doi.org/10.1038/s41588-020-00763-1
BIOS Consortium, i2QTL Consortium, Võsa, U., Claringbould, A., Westra, H-J., Bonder, M. J., Deelen, P., Zeng, B., Kirsten, H., Saha, A., Kreuzhuber, R., Yazar, S., Brugge, H., Oelen, R., de Vries, D. H., van der Wijst, M. G. P., Kasela, S., Pervjakova, N., Alves, I., ... Franke, L. (2021). Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression. Nature Genetics, 53, 1300-1310. https://doi.org/10.1038/s41588-021-00913-z
Mc Intyre, K., Lanting, P., Deelen, P., Wiersma, H. H., Vonk, J. M., Ori, A. P. S., Jankipersadsing, S. A., Warmerdam, R., van Blokland, I., Boulogne, F., Dijkema, M. X. L., Herkert, J. C., Claringbould, A., Bakker, O., Lopera Maya, E. A., Bültmann, U., Zhernakova, A., Reijneveld, S. A., Zijlstra, E., ... Franke, L. (2021). Lifelines COVID-19 cohort: investigating COVID-19 infection and its health and societal impacts in a Dutch population-based cohort. BMJ Open, 11(3), [e044474]. https://doi.org/10.1136/bmjopen-2020-044474
BIOS Consortium, van der Graaf, A., Zorro, M. M., Claringbould, A., Vosa, U., Aguirre-Gamboa, R., Li, C., Mooiweer, J., Ricano-Ponce, I., Borek, Z., Koning, F., Kooy-Winkelaar, Y., Sollid, L. M., Qiao, S-W., Kumar, V., Li, Y., Franke, L., Withoff, S., Wijmenga, C., ... Jonkers, I. (2021). Systematic Prioritization of Candidate Genes in Disease Loci Identifies TRAFD1 as a Master Regulator of IFN gamma Signaling in Celiac Disease. Frontiers in Genetics, 11, 562434. [562434]. https://doi.org/10.3389/fgene.2020.562434
van Blokland, I. V., Groot, H. E., Franke, L. H., van der Wijst, M. G. P., & van der Harst, P. (2021). Translational insights from single-cell technologies across the cardiovascular disease continuum. TRENDS IN CARDIOVASCULAR MEDICINE. https://doi.org/10.1016/j.tcm.2021.02.009
Lifelines COVID-19 cohort study, van Blokland, I. V., Lanting, P., Ori, A. P. S., Vonk, J. M., Warmerdam, R. C. A., Herkert, J. C., Boulogne, F., Claringbould, A., Lopera-Maya, E. A., Bartels, M., Hottenga, J-J., Ganna, A., & Karjalainen, J. (2021). Using symptom-based case predictions to identify host genetic factors that contribute to COVID-19 susceptibility. PLoS ONE, 16(8), [e0255402]. https://doi.org/10.1371/journal.pone.0255402

2020

BIOS Consortium, Ouwens, K. G., Jansen, R., Nivard, M. G., van Dongen, J., Frieser, M. J., Hottenga, J-J., Arindrarto, W., Claringbould, A., van Iterson, M., Mei, H., & Franke, L. (2020). A characterization of cis- and trans-heritability of RNA-Seq-based gene expression. European Journal of Human Genetics, 28(2), 253-263. https://doi.org/10.1038/s41431-019-0511-5
BIOS Consortium, Lu, X., Fraszczyk, E., van der Meer, T. P., van Faassen, M., Bloks, V. W., Kema, I. P., van Beek, A. P., Li, S., Franke, L., Westra, H-J., Xu, X., Huo, X., Snieder, H., Wolffenbuttel, B. H. R., & van Vliet-Ostaptchouk, J. V. (2020). An epigenome-wide association study identifies multiple DNA methylation markers of exposure to endocrine disruptors. Environment international, 144, [106016]. https://doi.org/10.1016/j.envint.2020.106016
BIOS Consortium, Aguirre-Gamboa, R., de Klein, N., di Tommaso, J., Claringbould, A., van der Wijst, M. G. P., de Vries, D., Brugge, H., Oelen, R., Vosa, U., Zorro, M. M., Chu, X., Bakker, O. B., Borek, Z., Ricano-Ponce, I., Deelen, P., Xu, C-J., Swertz, M., Jonkers, I., ... Li, Y. (2020). Deconvolution of bulk blood eQTL effects into immune cell subpopulations. Bmc Bioinformatics, 21(1), [243]. https://doi.org/10.1101/548669
Claus, L. R., Boulogne, F., Lilien, M. R., Rookmaaker, M. B., van der Zwaag, A., Nguyen, T. Q., Verhaar, M. C., Knoers, N. V. A. M., Deelen, P., Franke, L., de Borst, M. H., & van Eerde, A. M. (2020). GeNepher: building a data- and biobank for (suspected) hereditary renal disease. European Journal of Human Genetics, 28(SUPPL 1), 821-822.
Folkersen, L., Gustafsson, S., Wang, Q., Hansen, D. H., Hedman, Å. K., Schork, A., Page, K., Zhernakova, D. V., Wu, Y., Peters, J., Eriksson, N., Bergen, S. E., Boutin, T. S., Bretherick, A. D., Enroth, S., Kalnapenkis, A., Gådin, J. R., Suur, B. E., Chen, Y., ... Mälarstig, A. (2020). Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals. Nature Metabolism, 2(10), 1135-1148. https://doi.org/10.1038/s42255-020-00287-2
Huang, Y., Ollikainen, M., Muniandy, M., Zhang, T., van Dongen, J., Hao, G., van Der Most, P. J., Pan, Y., Pervjakova, N., Sun, Y., Hui, Q., Lahti, J., Fraszczyk, E., Lu, X., Sun, D., Richard, M. A., Willemsen, G., Heikkila, K., Leach, I. M., ... Snieder, H. (2020). Identification, Heritability, and Relation With Gene Expression of Novel DNA Methylation Loci for Blood Pressure. Hypertension, 76(1), 195-205. https://doi.org/10.1161/HYPERTENSIONAHA.120.14973
de Vries, D. H., Matzaraki, V., Bakker, O. B., Brugge, H., Westra, H-J., Netea, M. G., Franke, L., Kumar, V., & van der Wijst, M. G. P. (2020). Integrating GWAS with bulk and single-cell RNA-sequencing reveals a role for LY86 in the anti-Candida host response. PLoS Pathogens, 16(4), [1008408]. https://doi.org/10.1371/journal.ppat.1008408
Lifelines Cohort Study, Lopera Maya, E. A., van der Graaf, A., Lanting, P., van der Geest, M., Fu, J., Swertz, M., Franke, L., Wijmenga, C., Deelen, P., Zhernakova, A., & Sanna, S. (2020). Lack of Association Between Genetic Variants at ACE2 and TMPRSS2 Genes Involved in SARS-CoV-2 Infection and Human Quantitative Phenotypes. Frontiers in Genetics, 11, [613]. https://doi.org/10.3389/fgene.2020.00613
BIOS Consortium, van der Graaf, A., Claringbould, A., Rimbert, A., Westra, H-J., Li, Y., Wijmenga, C., Sanna, S., & Franke, L. (2020). Mendelian randomization while jointly modeling cis genetics identifies causal relationships between gene expression and lipids. Nature Communications, 11(1), [4930]. https://doi.org/10.1038/s41467-020-18716-x
Lanting, P., Drenth, E., Boven, L., van Hoek, A., Hijlkema, A., Poot, E., van der Vries, G., Schoevers, R., Horwitz, E., Gans, R., Kosterink, J., Plantinga, M., van Langen, I., Ranchor, A., Wijmenga, C., Franke, L., Wilffert, B., & Sijmons, R. (2020). Practical Barriers and Facilitators Experienced by Patients, Pharmacists and Physicians to the Implementation of Pharmacogenomic Screening in Dutch Outpatient Hospital Care-An Explorative Pilot Study. Journal of personalized medicine, 10(4), 1-13. [293]. https://doi.org/10.3390/jpm10040293
Bangma, A., Voskuil, M. D., Uniken Venema, W. T. C., Brugge, H., Hu, S., Lanting, P., Franke, L., Dijkstra, G., Festen, E. A. M., & Weersma, R. K. (2020). Predicted efficacy of a pharmacogenetic passport for inflammatory bowel disease. Alimentary Pharmacology & Therapeutics, 51(11), 1105-1115. https://doi.org/10.1111/apt.15762
Van Der Wijst, M. G. P., De Vries, D. H., Groot, H. E., Trynka, G., Hon, C. C., Bonder, M. J., Stegle, O., Nawijn, M. C., Idaghdour, Y., Van Der Harst, P., Ye, C. J., Powell, J., Theis, F. J., Mahfouz, A., Heing, M., & Franke, L. (2020). The single-cell eQTLGen consortium. eLife, 9, [52155]. https://doi.org/10.7554/eLife.52155

2019

BIOS Consortium (2019). A linear mixed-model approach to study multivariate gene-environment interactions. Nature Genetics, 51(1), 180-186. https://doi.org/10.1038/s41588-018-0271-0
BIOS Consortium (2019). Allele specific expression identifies rare variants as cause for extreme allelic imbalance. European Journal of Human Genetics, 27, 601.
Clark, D. W., Okada, Y., Moore, K. H. S., Mason, D., Pirastu, N., Gandin, I., Mattsson, H., Barnes, C. L. K., Lin, K., Zhao, J. H., Deelen, P., Rohde, R., Schurmann, C., Guo, X., Giulianini, F., Zhang, W., Medina-Gomez, C., Karlsson, R., Bao, Y., ... Wilson, J. F. (2019). Associations of autozygosity with a broad range of human phenotypes. Nature Communications, 10(1), [4957]. https://doi.org/10.1038/s41467-019-12283-6
Sanna, S., van Zuydam, N. R., Mahajan, A., Kurilshikov, A., Vich Vila, A., Võsa, U., Mujagic, Z., Masclee, A. A. M., Jonkers, D. M. A. E., Oosting, M., Joosten, L. A. B., Netea, M. G., Franke, L., Zhernakova, A., Fu, J., Wijmenga, C., & McCarthy, M. I. (2019). Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases. Nature Genetics, 51(4), 600-605. https://doi.org/10.1038/s41588-019-0350-x
Zeng, B., Lloyd-Jones, L. R., Montgomery, G. W., Metspalu, A., Esko, T., Franke, L., Vosa, U., Claringbould, A., Brigham, K. L., Quyyumi, A. A., Idaghdour, Y., Yang, J., Visscher, P. M., Powell, J. E., & Gibson, G. (2019). Comprehensive Multiple eQTL Detection and Its Application to GWAS Interpretation. Genetics, 212(3), 905-918. https://doi.org/10.1534/genetics.119.302091
BIOS Consortium, van Dongen, J., Zilhao, N. R., Sugden, K., Hannon, E. J., Mill, J., Caspi, A., Agnew-Blais, J., Arseneault, L., Corcoran, D. L., Moffitt, T. E., Poulton, R., Franke, B., & Boomsma, D. (2019). Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults. Biological Psychiatry, 86(8), 599-607. https://doi.org/10.1016/j.biopsych.2019.02.016
BIOS Consortium, van Rooij, J., Mandaviya, P. R., Claringbould, A., Felix, J. F., van Dongen, J., Jansen, R., Franke, L., 't Hoen, P. A. C., Heijmans, B., & van Meurs, J. B. J. (2019). Evaluation of commonly used analysis strategies for epigenome- and transcriptome-wide association studies through replication of large-scale population studies. Genome Biology, 20(1), [235]. https://doi.org/10.1186/s13059-019-1878-x
CommonMind Consortium, Psychiat Genomics Consortium, iPSYCH-GEMS Schizophrenia Working, Huckins, L. M., Dobbyn, A., Ruderfer, D. M., Hoffman, G., Wang, W., Pardinas, A. F., Rajagopal, V. M., Als, T. D., Nguyen, H. T., Girdhar, K., Boocock, J., Roussos, P., Fromer, M., Kramer, R., Purcell, S., Demontis, D., ... Stahl, E. A. (2019). Gene expression imputation across multiple brain regions provides insights into schizophrenia risk. Nature Genetics, 51(4), 659-674. https://doi.org/10.1038/s41588-019-0364-4
23and Me Res Team, eQTLgen Consortium, Int Cannabis Consortium, & Soc Sci Genetic Association Con (2019). Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences. Nature Genetics, 51(2), 245-257. https://doi.org/10.1038/s41588-018-0309-3
eQTLgen Consortium, Timmers, P. R., Mounier, N., Lall, K., Fischer, K., Ning, Z., Feng, X., Bretherick, A. D., & Clark, D. W. (2019). Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances. eLife, 8, [39856]. https://doi.org/10.7554/eLife.39856
van Arensbergen, J., Pagie, L., FitzPatrick, V. D., de Haas, M., Baltissen, M. P., Comoglio, F., van der Weide, R. H., Teunissen, H., Vosa, U., Franke, L., de Wit, E., Vermeulen, M., Bussemaker, H. J., & van Steensel, B. (2019). High-throughput identification of human SNPs affecting regulatory element activity. Nature Genetics, 51(7), 1160-+. https://doi.org/10.1038/s41588-019-0455-2
Deelen, P., van Dam, S., Karjalainen, J. M., Brugge, H., Folkertsma, P., van Diemen, C. C., Kerstjens-Frederikse, W. S., Herkert, J. C., Gillett, T., Swertz, M. A., & Franke, L. (2019). Improving diagnostic yield of exome-sequencing through prioritization of genes with predicted HPO assignments. European Journal of Human Genetics, 27, 537-537.
Deelen, P., van Dam, S., Herkert, J. C., Karjalainen, J. M., Brugge, H., Abbott, K. M., van Diemen, C. C., van der Zwaag, P. A., Gerkes, E. H., Zonneveld-Huijssoon, E., Boer-Bergsma, J. J., Folkertsma, P., Gillett, T., van der Velde, K. J., Kanninga, R., van den Akker, P. C., Jan, S. Z., Hoorntje, E. T., Te Rijdt, W. P., ... Franke, L. (2019). Improving the diagnostic yield of exome-sequencing by predicting gene-phenotype associations using large-scale gene expression analysis. Nature Communications, 10(1), [2837]. https://doi.org/10.1038/s41467-019-10649-4
Chu, X., Jaeger, M., Bakker, O. B., Aguirre-Gamboa, R., Oosting, M., Smeekens, S. P., Withoff, S., Netea-Maier, R. T., Koenen, H. J. P. M., Joosten, I., Xavier, R. J., Franke, L., Joosten, L. A. B., Sanna, S., Kumar, V., Wijmenga, C., Netea, M. G., & Li, Y. (2019). Integration of similar to 10,000 metabolite features with genotype data and immune phenotypes reveals genetic determinants and common regulatory modules. European Journal of Human Genetics, 27, 787-787.
BBMRI Metabolomics Consortium (2019). Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine. Neurology, 92(16), E1899-E1911. https://doi.org/10.1212/WNL.0000000000007313
Porcu, E., Rueger, S., Lepik, K., eQTLgen Consortium, & BIOS Consortium (2019). Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits. Nature Communications, 10, [3300]. https://doi.org/10.1038/s41467-019-10936-0
Kilpelainen, T. O., Nolte, I. M., van der Most, P. J., Verweij, N., Snieder, H., van der Ende, M. Y., Oldehinkel, A. J., van der Harst, P., Van Vliet-Ostaptchouk, J. V., Lifelines Cohort Study, & Wang, Y. X. (2019). Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity. Nature Communications, 10(1), [376]. https://doi.org/10.1038/s41467-018-08008-w
Vojinovic, D., Radjabzadeh, D., Kurilshikov, A., Amin, N., Wijmenga, C., Franke, L., Ikram, M. A., Uitterlinden, A. G., Zhernakova, A., Fu, J., Kraaij, R., & van Duijn, C. M. (2019). Relationship between gut microbiota and circulating metabolites in population-based cohorts. Nature Communications, 10(1), [5813]. https://doi.org/10.1038/s41467-019-13721-1
GoNL Consortium, BIOS Consortium, Jadhav, B., Monajemi, R., Gagalova, K. K., Ho, D., Draisma, H. H. M., van de Wiel, M. A., Franke, L., Heijmans, B. T., van Meurs, J., Jansen, R., t Hoen, P. A. C., Sharp, A. J., & Kielbasa, S. M. (2019). RNA-Seq in 296 phased trios provides a high-resolution map of genomic imprinting. BMC Biology, 17(1), [50]. https://doi.org/10.1186/s12915-019-0674-0
Peters, V., Tigchelaar, E., Imhann, F., Dekens, J., Swertz, M., Franke, L., Wijmenga, C., Weersma, R. K., Alizadeh, B., Dijkstra, G., & Campmans-Kuijpers, M. J. (2019). Sa2029 – Habitual dietary intake of dutch IBD patients differs from population controls: A case-control study. Gastroenterology, 156(6), S477-S478. https://doi.org/10.1016/S0016-5085(19)38052-7 Abstract
BIOS Consortium, & GoNL Consortium (2019). Skewed X-inactivation is common in the general female population. European Journal of Human Genetics, 27(3), 455-465. https://doi.org/10.1038/s41431-018-0291-3
BIOS Consortium, KORA Study Grp, Schlicht, K., Nyczka, P., Caliebe, A., Freitag-Wolf, S., Claringbould, A., Franke, L., Vosa, U., Kardia, S. L. R., Smith, J. A., Zhao, W., Gieger, C., Peters, A., Prokisch, H., Strauch, K., Baurecht, H., Weidinger, S., Rosenstiel, P., ... Krawczak, M. (2019). The metabolic network coherence of human transcriptomes is associated with genetic variation at the cadherin 18 locus. HUMAN GENETICS, 138(4), 375-388. https://doi.org/10.1007/s00439-019-01994-x

2018

BIOS Consortium (2018). A SNP panel for identification of DNA and RNA specimens. BMC Genomics, 19(90). https://doi.org/10.1186/s12864-018-4482-7
van der Wijst, M. G. P., de Vries, D. H., Brugge, H., Westra, H-J., & Franke, L. (2018). An integrative approach for building personalized gene regulatory networks for precision medicine. Genome medicine, 10, [96]. https://doi.org/10.1186/s13073-018-0608-4
BIOS Consortium, GLOBAL Meth QTL, Parmar, P., Lowry, E., Cugliari, G., Suderman, M., Wilson, R., Karhunen, V., Andrew, T., Wiklund, P., Wielscher, M., Guarrera, S., Teumer, A., Lehne, B., Milani, L., de Klein, N., Mishra, P. P., Melton, P. E., Mandaviya, P. R., ... Verweij, N. (2018). Association of maternal prenatal smoking GFI1-locus and cardiometabolic phenotypes in 18,212 adults. EBioMedicine, 38, 206-216. https://doi.org/10.1016/j.ebiom.2018.10.066
Pirastu, N., Joshi, P. K., de Vries, P. S., Cornelis, M. C., McKeigue, P. M., Keum, N., Franceschini, N., Colombo, M., Giovannucci, E. L., Spiliopoulou, A., Franke, L., North, K. E., Kraft, P., Morrison, A. C., Esko, T., & Wilson, J. F. (2018). Author Correction: GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk. Nature Communications, 9(1), 2536. https://doi.org/10.1038/s41467-018-04857-7
Lifelines Cohort Study, Zhernakova, D. V., Le, T. H., Kurilshikov, A., Atanasovska, B., Bonder, M. J., Sanna, S., Claringbould, A., Võsa, U., Deelen, P., Franke, L., de Boer, R. A., Kuipers, F., Netea, M. G., Hofker, M. H., Wijmenga, C., Zhernakova, A., & Fu, J. (2018). Author Correction: Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome. Nature Genetics, 50(12), [1752]. https://doi.org/10.1038/s41588-018-0275-9
BIOS Consortium, Luijk, R., Wu, H., Ward-Caviness, C. K., Hannon, E., Carnero-Montoro, E., Min, J. L., Mandaviya, P., Mueller-Nurasyid, M., Mei, H., van der Maarel, S. M., Relton, C., Mill, J., Waldenberger, M., Bell, J. T., Jansen, R., Zhernakova, A., Franke, L., 't Hoen, P. A. C., ... Heijmans, B. T. (2018). Autosomal genetic variation is associated with DNA methylation in regions variably escaping X-chromosome inactivation. Nature Communications, 9(1), 3738. [3738]. https://doi.org/10.1038/s41467-018-05714-3
Amini, M., Vonk, J. M., Abbasi, A., Prins, B. P., Bruinenberg, M., Franke, L., van der Harst, P., Navis, G., Koppelman, G. H., Wolffenbuttel, B. H. R., Boezen, H. M., Snieder, H., Chasman, D. I., & Alizadeh, B. Z. (2018). Blood Eosinophil Count and Metabolic, Cardiac and Pulmonary Outcomes: A Mendelian Randomization Study. Twin research and human genetics, 21(2), 89-100. https://doi.org/10.1017/thg.2018.6
Bolling, M. C., Jan, S. Z., Pasmooij, A. M. G., Lemmink, H. H., Franke, L. H., Yenamandra, V. K., Sinke, R. J., van den Akker, P. C., & Jonkman, M. F. (2018). Generalized Ichthyotic Peeling Skin Syndrome due to FLG2 Mutations. Journal of Investigative Dermatology, 138(8), 1881-1884. https://doi.org/10.1016/j.jid.2018.01.038
Bolling, M., Jan, S., Pasmooij, A., Lemmink, H., Franke, L., Yenamandra, V., Sinke, R., van den Akker, P., & Jonkman, M. F. (2018). Generalized ichthyotic peeling skin syndrome due to FLG2 mutations. Journal of Investigative Dermatology, 138(5), S128.
Lifelines Cohort Study, Ligthart, S., Vaez, A., Võsa, U., Stathopoulou, M. G., de Vries, P. S., Prins, B. P., Van der Most, P. J., Tanaka, T., Naderi, E., Rose, L. M., Wu, Y., Karlsson, R., Barbalic, M., Lin, H., Pool, R., Zhu, G., Macé, A., Sidore, C., ... Amini, M. (2018). Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders. American Journal of Human Genetics, 103(5), 691-706. https://doi.org/10.1016/j.ajhg.2018.09.009, https://doi.org/10.1016/j.ajhg.2018.09.009
BIOS Consortium, Luijk, R., Dekkers, K. F., van Iterson, M., Arindrarto, W., Claringbould, A., Hop, P., Boomsma, D., van Duijn, C. M., van Greevenbroek, M. M. J., Veldink, J. H., Wijmenga, C., Franke, L., 't Hoend, P. A. C., Jansen, R., van Meurs, J., Mei, H., Slagboomi, P. E., Heijmans, B. T., & van Zwet, E. W. (2018). Genome-wide identification of directed gene networks using large-scale population genomics data. Nature Communications, 9(1), 3097. [3097]. https://doi.org/10.1038/s41467-018-05452-6
Vich Vila, A., Imhann, F., Collij, V., Jankipersadsing, S. A., Gurry, T., Mujagic, Z., Kurilshikov, A., Bonder, M. J., Jiang, X., Tigchelaar, E. F., Dekens, J., Peters, V., Voskuil, M. D., Visschedijk, M. C., van Dullemen, H. M., Keszthelyi, D., Swertz, M. A., Franke, L., Alberts, R., ... Weersma, R. K. (2018). Gut microbiota composition and functional changes in inflammatory bowel disease and irritable bowel syndrome. Science Translational Medicine, 10(472). https://doi.org/10.1126/scitranslmed.aap8914
Lifelines Cohort Study (2018). Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome. Nature Genetics, 50(11), 1524-+. https://doi.org/10.1038/s41588-018-0224-7
Bakker, O. B., Aguirre-Gamboa, R., Sanna, S., Oosting, M., Smeekens, S. P., Jaeger, M., Zorro, M., Vosa, U., Withoff, S., Netea-Maier, R. T., Koenen, H. J. P. M., Joosten, I., Xavier, R. J., Franke, L., Joosten, L. A. B., Kumar, V., Wijmenga, C., Netea, M. G., & Li, Y. (2018). Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses. Nature Immunology, 19(7), 776-786. https://doi.org/10.1038/s41590-018-0121-3
Barbieri, R., Venema, W. U., Vich Vila, A., Li, Y., Franke, L., van Dijk, F., De Klein, N., Swertz, M., Sanna, S., Voskuil, M. D., Rivas, M., Xavier, R., Daly, M., Festen, E. A., & Weersma, R. K. (2018). Integration of whole-exome sequencing and RNA sequencing of intestinal biopsies in inflammatory bowel disease identifies inflammation-dependent effects. Journal of Crohn's and Colitis, 12, S8-S9.
Imhann, F., Vich Vila, A., Bonder, M. J., Fu, J., Gevers, D., Visschedijk, M. C., Spekhorst, L. M., Alberts, R., Franke, L., van Dullemen, H. M., Ter Steege, R. W. F., Huttenhower, C., Dijkstra, G., Xavier, R. J., Festen, E. A. M., Wijmenga, C., Zhernakova, A., & Weersma, R. K. (2018). Interplay of host genetics and gut microbiota underlying the onset and clinical presentation of inflammatory bowel disease. Gut, 67(1), 108-119. https://doi.org/10.1136/gutjnl-2016-312135
MiBioGen Consortium Initiative (2018). Meta-analysis of human genome-microbiome association studies: The MiBioGen consortium initiative. Microbiome, 6(1), [101]. https://doi.org/10.1186/s40168-018-0479-3
van Setten, J., Brody, J. A., Jamshidi, Y., Swenson, B. R., Butler, A. M., Campbell, H., Del Greco, F. M., Evans, D. S., Gibson, Q., Gudbjartsson, D. F., Kerr, K. F., Krijthe, B. P., Lyytikainen, L-P., Mueller, C., Mueller-Nurasyid, M., Nolte, I. M., Padmanabhan, S., Ritchie, M. D., Robino, A., ... Snieder, H. (2018). PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity. Nature Communications, 9(1), [2904]. https://doi.org/10.1038/s41467-018-04766-9
Peters, V., Tigchelaar, E., Campmans-Kuijpers, M., Sheedfar, F., Imhann, F., Dekens, J., Wijmenga, C., Swertz, M., Franke, L., Weersma, R., Dijkstra, G., & Alizadeh, B. (2018). P831 - Habitual dietary intake of Dutch IBD patients differs from population controls: A case-control study. Journal of Crohn's and Colitis, 12, S536-S536. [P831]. https://doi.org/10.1093/ecco-jcc/jjx180.958
Pirastu, N., Joshi, P. K., de Vries, P. S., Cornelis, M. C., Keum, N., Franceschini, N., Colombo, M., Giovannucci, E. L., Spiliopoulou, A., Franke, L., North, K. E., Kraft, P., Morrison, A. C., Esko, T., & Wilson, J. F. (2018). Reply to 'Misestimation of heritability and prediction accuracy of male-pattern baldness'. Nature Communications, 9(1), 2538. [2538]. https://doi.org/10.1038/s41467-018-04808-2
Lifelines Cohort Study, & BIOS Consortium (2018). Single-cell RNA sequencing identifies celltype-specific cis-eQTLs and co-expression QTLs. Nature Genetics, 50(4), 493-497. https://doi.org/10.1038/s41588-018-0089-9
Scholz, R. W., Bartelsman, E. J., Diefenbach, S., Franke, L., Grunwald, A., Helbing, D., Hill, R., Hilty, L., Hojer, M., Klauser, S., Montag, C., Parycek, P., Prote, J. P., Renn, O., Reichel, A., Schuh, G., Steiner, G., & Pereira, G. V. (2018). Unintended Side Effects of the Digital Transition: European Scientists' Messages from a Proposition-Based Expert Round Table. Sustainability, 10(6), [2001]. https://doi.org/10.3390/su10062001

2017

van Dam, S., Võsa, U., van der Graaf, A., Franke, L., & de Magalhães, J. P. (2018). Gene co-expression analysis for functional classification and gene-disease predictions. Briefings in Bioinformatics, 19(4), 575-592. https://doi.org/10.1093/bib/bbw139
Linner, R. K., Marioni, R. E., Rietveld, C. A., Simpkin, A. J., Davies, N. M., Watanabe, K., Armstrong, N. J., Auro, K., Baumbach, C., Bonder, M. J., Buchwald, J., Fiorito, G., Ismail, K., Iurato, S., Joensuu, A., Karell, P., Kasela, S., Lahti, J., Mcrae, A. F., ... BIOS Consortium (2017). An epigenome-wide association study meta-analysis of educational attainment. Molecular Psychiatry, 22(12), 1680-1690. https://doi.org/10.1038/mp.2017.210
Matzaraki, V., Gresnigt, M. S., Jaeger, M., Ricano-Ponce, I., Johnson, M. D., Oosting, M., Franke, L., Withoff, S., Perfect, J. R., Joosten, L. A. B., Kullberg, B. J., van de Veerdonk, F. L., Jonkers, I., Li, Y., Wijmenga, C., Netea, M. G., & Kumar, V. (2017). An integrative genomics approach identifies novel pathways that influence candidaemia susceptibility. PLoS ONE, 12(7), [e0180824]. https://doi.org/10.1371/journal.pone.0180824
Macé, A., Tuke, M. A., Deelen, P., Kristiansson, K., Mattsson, H., Nõukas, M., Sapkota, Y., Schick, U., Porcu, E., Rüeger, S., McDaid, A. F., Porteous, D., Winkler, T. W., Salvi, E., Shrine, N., Liu, X., Ang, W. Q., Zhang, W., Feitosa, M. F., ... Kutalik, Z. (2017). CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits. Nature Communications, 8(1), [744]. https://doi.org/10.1038/s41467-017-00556-x
Marshall, C. R., Howrigan, D. P., Merico, D., Thiruvahindrapuram, B., Wu, W., Greer, D. S., Antaki, D., Shetty, A., Holmans, P. A., Pinto, D., Gujral, M., Brandler, W. M., Malhotra, D., Wang, Z., Fajarado, K. V. F., Maile, M. S., Ripke, S., Agartz, I., Albus, M., ... Psychosis Endophenotypes (2017). Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects. Nature Genetics, 49(1), 27-35. https://doi.org/10.1038/ng.3725
Tang, A. T., Hoi, J. P. C., Kotzin, J. J., Yang, Y., Hong, C. C., Hobson, N., Girard, R., Zeineddine, H. A., Lightle, R., Moore, T., Cao, Y., Shenkar, R., Chen, M., Mericko, P., Yang, J., Li, L., Tanes, C., Kobuley, D., Vosa, U., ... Kahn, M. L. (2017). Endothelial TLR4 and the microbiome drive cerebral cavernous malformations. Nature, 545(7654), 305-310. https://doi.org/10.1038/nature22075
van Dongen, J., Suderman, M., Sugden, K., Ismail, K., Mulder, R. H., Kupper, L. K., Bustamante, M., Alemany, S., Bonder, M. J., Parmar, P., Lowry, E., Jansen, R., Baselmans, B., Nivard, M., Corcoran, D., Poulton, R., Mill, J., Hannon, E., Arseneault, L., ... BIOS Consortium (2017). Epigenome-wide association study meta-analysis of aggressive behavior. Behavior Genetics, 47(6), 662-663.
Wahl, S., Drong, A. W., Lehne, B., Loh, M., Scott, W. R., Kunze, S., Tsai, P-C., Ried, J. S., Zhang, W., Yang, Y., Tan, S., Fiorito, G., Franke, L., Guarrera, S., Kasela, S., Kriebel, J., Richmond, R. C., Adamo, M., Afzal, U., ... Chambers, J. C. (2017). Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity. Nature, 541(81), 81-86. https://doi.org/10.1038/nature20784
Nibbeling, E. A. R., Duarri, A., Verschuuren-Bemelmans, C. C., Fokkens, M. R., Karjalainen, J. M., Smeets, C. J. L. M., de Boer-Bergsma, J. J., van der Vries, G., Dooijes, D., Bampi, G. B., van Diemen, C., Brunt, E., Ippel, E., Kremer, B., Vlak, M., Adir, N., Wijmenga, C., Warrenburg, B. P. C. V. D., Franke, L., ... Verbeek, D. S. (2017). Exome sequencing and network analysis identifies shared mechanisms underlying spinocerebellar ataxia. Brain, 140(11), 2860-2878. https://doi.org/10.1093/brain/awx251
van der Velde, K. J., de Boer, E. N., van Diemen, C. C., Sikkema-Raddatz, B., Abbott, K. M., Knopperts, A., Franke, L., Sijmons, R. H., de Koning, T. J., Wijmenga, C., Sinke, R. J., & Swertz, M. A. (2017). GAVIN: Gene-Aware Variant INterpretation for medical sequencing. Genome Biology, 18(1), [6]. https://doi.org/10.1186/s13059-016-1141-7
Soderquest, K., Hertweck, A., Giambartolomei, C., Henderson, S., Mohamed, R., Goldberg, R., Perucha, E., Franke, L., Herrero, J., Plagnol, V., Jenner, R. G., & Lord, G. M. (2017). Genetic variants alter T-bet binding and gene expression in mucosal inflammatory disease. PLoS genetics, 13(2), [e1006587]. https://doi.org/10.1371/journal.pgen.1006587
Mandaviya, P. R., Joehanes, R., Aissi, D., Kuehnel, B., Marioni, R. E., Truong, V., Stolk, L., Beekman, M., Bonder, M. J., Franke, L., Gieger, C., Huan, T., Ikram, M. A., Kunze, S., Liang, L., Lindemann, J., Liu, C., McRae, A. F., Mendelson, M. M., ... Charge Consortium Epigenetics Grp (2017). Genetically defined elevated homocysteine levels do not result in widespread changes of DNA methylation in leukocytes. PLoS ONE, 12(10), [e0182472]. https://doi.org/10.1371/journal.pone.0182472
Day, F. R., Thompson, D. J., Helgason, H., Chasman, D. I., Finucane, H., Sulem, P., Ruth, K. S., Whalen, S., Sarkar, A. K., Albrecht, E., Altmaier, E., Amini, M., Barbieri, C. M., Boutin, T., Campbell, A., Demerath, E., Giri, A., He, C., Hottenga, J. J., ... PRACTICAl Consortium (2017). Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk. Nature Genetics, 49(6), 834-841. https://doi.org/10.1038/ng.3841
Pirastu, N., Joshi, P. K., de Vries, P. S., Cornelis, M. C., McKeigue, P. M., Keum, N., Franceschini, N., Colombo, M., Giovannucci, E. L., Spiliopoulou, A., Franke, L., North, K. E., Kraft, P., Morrison, A. C., Esko, T., & Wilson, J. F. (2017). GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk. Nature Communications, 8, [1584]. https://doi.org/10.1038/s41467-017-01490-8
Wild, P. S., Felix, J. F., Schillert, A., Teumer, A., Chen, M-H., Leening, M. J. G., Voelker, U., Grossmann, V., Brody, J. A., Irvin, M. R., Shah, S. J., Pramana, S., Lieb, W., Schmidt, R., Stanton, A. V., Malzahn, D., Smith, A. V., Sundstrom, J., Minelli, C., ... KNHI Investigators (2017). Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. CLIN Journal, 127(5), 1798-1812. https://doi.org/10.1172/JCI84840
Nolte, I. M., van der Most, P. J., Alizadeh, B. Z., de Bakker, P. I., Boezen, H. M., Bruinenberg, M., Franke, L., van der Harst, P., Navis, G., Postma, D. S., Rots, M. G., Stolk, R. R. P., Swertz, M. A., Wolffenbuttel, B. H., Wijmenga, C., & Snieder, H. (2017). Missing heritability: Is the gap closing? An analysis of 32 complex traits in the LifeLines Cohort Study. Genetic epidemiology, 39(7), 572-573. https://doi.org/10.1038/ejhg.2017.50
Nolte, I. M., van der Most, P. J., Alizadeh, B. Z., de Bakker, P. I. W., Boezen, H. M., Bruinenberg, M., Franke, L., van der Harst, P., Navis, G., Postma, D. S., Rots, M. G., Stolk, R. P., Swertz, M. A., Wolffenbuttel, B. H. R., Wijmenga, C., & Snieder, H. (2017). Missing heritability: Is the gap closing? An analysis of 32 complex traits in the Lifelines Cohort Study. European Journal of Human Genetics, 25(7), 877-885. https://doi.org/10.1038/ejhg.2017.50
Nolte, I. M., Most, P. J. V. D., Alizadeh, B. Z., Bakker, P. IW. D., Boezen, H. M., Bruinenberg, M., Franke, L., Harst, P. V. D., Navis, G., Postma, D. S., Rots, M. G., Stolk, R. P., Swertz, M. A., Wolffenbuttel, B. HR., Wijmenga, C., & Snieder, H. (2017). Missing heritability: is the gap closing? An analysis of 32 complex traits in the Lifelines Cohort Study. European Journal of Human Genetics, 25, 877-885. https://doi.org/10.1038/ejhg.2017.50
Lepamets, M., Lepik, K., Kals, M., Carmeli, C., Claringbould, A., Bochud, M., Stringhini, S., Wijmenga, C., Franke, L., Magi, R., & Kutalik, Z. (2017). New Quality Measure for CNV: A Multi-Omics Approach. Human heredity, 83(1), 16-16.
Acuna-Hidalgo, R., Deriziotis, P., Steehouwer, M., Gilissen, C., Graham, S. A., van Dam, S., Hoover-Fong, J., Telegrafi, A. B., Destree, A., Smigiel, R., Lambie, L. A., Kayserili, H., Altunoglu, U., Lapi, E., Uzielli, M. L. G., Aracena, M., Nur, B. G., Mihci, E., Moreira, L. M. A., ... van Bon, B. W. M. (2017). Overlapping SETBP1 gain-of-function mutations in Schinzel-Giedion syndrome and hematologic malignancies. PLoS genetics, 13(3). https://doi.org/10.1371/journal.pgen.1006683
Kasela, S., Kisand, K., Tserel, L., Kaleviste, E., Remm, A., Fischer, K., Esko, T., Westra, H-J., Fairfax, B. P., Makino, S., Knight, J. C., Franke, L., Metspalu, A., Peterson, P., & Milani, L. (2017). Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4(+) versus CD8(+) T cells. PLoS genetics, 13(3). https://doi.org/10.1371/journal.pgen.1006643
Kreiner, E., Waage, J., Standl, M., Brix, S., Pers, T. H., Couto Alves, A., Warrington, N. M., Tiesler, C. M., Fuertes, E., Franke, L., Hirschhorn, J. N., James, A., Simpson, A., Tung, J. Y., Koppelman, G. H., Postma, D. S., Pennell, C. E., Jarvelin, M-R., Custovic, A., ... Bønnelykke, K. (2017). Shared genetic variants suggest common pathways in allergy and autoimmune diseases. Journal of Allergy and Clinical Immunology, 140(3), 771-781. https://doi.org/10.1016/j.jaci.2016.10.055
Claringbould, A., de Klein, N., & Franke, L. (2017). The genetic architecture of molecular traits. Current Opinion in Systems Biology, 1, 25-31. https://doi.org/10.1016/j.coisb.2017.01.002

2016

Bonder, M. J., Luijk, R., Pital-Zhernakova, D., Moed, M., Deelen, P., Vermaat, M., van Iterson, M., van Dijk, F., van Galen, M., Bot, J., Slieker, R. C., Jhamai, P. M., Verbiest, M., Suchiman, H. E. D., Verkerk, M., van der Breggen, R., van Rooij, J., Lakenberg, N., Arindrarto, W., ... BIOS Consortium (2017). Disease variants alter transcription factor levels and methylation of their binding sites. Nature Genetics, 49(1), 131-138. https://doi.org/10.1038/ng.3721
Pital-Zhernakova, D., Deelen, P., Vermaat, M., van Iterson, M., van Galen, M., Arindrarto, W., van 't Hof, P., Mei, H., van Dijk, F., Westra, H-J., Bonder, M. J., van Rooij, J., Verkerk, M., Jhamai, P. M., Moed, M., Kielbasa, S. M., Bot, J., Nooren, I., Pool, R., ... Franke, L. (2017). Identification of context-dependent expression quantitative trait loci in whole blood. Nature Genetics, 49(1), 139-145. https://doi.org/10.1038/ng.3737
Li, Y., Oosting, M., Smeekens, S. P., Jaeger, M., Aguirre-Gamboa, R., Le, K. T. T., Deelen, P., Ricano-Ponce, I., Schoffelen, T., Jansen, A. F. M., Swertz, M. A., Withoff, S., van de Vosse, E., van Deuren, M., van de Veerdonk, F., Zhernakova, A., van der Meer, J. W. M., Xavier, R. J., Franke, L., ... Netea, M. G. (2016). A Functional Genomics Approach to Understand Variation in Cytokine Production in Humans. Cell, 167(4), 1099-1110. https://doi.org/10.1016/j.cell.2016.10.017
Slieker, R. C., van Iterson, M., Luijk, R., Beekman, M., Zhernakova, D. V., Moed, M. H., Mei, H., van Galen, M., Deelen, P., Bonder, M. J., Zhernakova, A., Uitterlinden, A. G., Tigchelaar, E. F., Stehouwer, C. D. A., Schalkwijk, C. G., van der Kallen, C. J. H., Hofman, A., van Heemst, D., de Geus, E. J., ... BIOS Consortium (2016). Age-related accrual of methylomic variability is linked to fundamental ageing mechanisms. Genome Biology, 17, [191]. https://doi.org/10.1186/s13059-016-1053-6
Ellinghaus, D., Jostins, L., Spain, S. L., Cortes, A., Bethune, J., Han, B., Park, Y. R., Raychaudhuri, S., Pouget, J. G., Huebenthal, M., Folseraas, T., Wang, Y., Esko, T., Metspalu, A., Westra, H-J., Franke, L., Pers, T. H., Weersma, R. K., Collij, V., ... PAGE (2016). Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. Nature Genetics, 48(5), 510-518. https://doi.org/10.1038/ng.3528
Dekkers, K. F., van Iterson, M., Slieker, R. C., Moed, M. H., Bonder, M. J., van Galen, M., Mei, H., Zhernakova, D. V., van den Berg, L. H., Deelen, J., van Dongen, J., van Heemst, D., Hofman, A., Hottenga, J. J., van der Kallen, C. J. H., Schalkwijk, C. G., Stehouwer, C. D. A., Tigchelaar, E. F., Uitterlinden, A. G., ... BIOS Consortium (2016). Blood lipids influence DNA methylation in circulating cells. Genome Biology, 17, [138]. https://doi.org/10.1186/s13059-016-1000-6
Pers, T. H., Timshel, P., Ripke, S., Lent, S., Sullivan, P. F., O'Donovan, M. C., Franke, L., Hirschhorn, J. N., & Schizophrenia Working Grp Psychiat (2016). Comprehensive analysis of schizophrenia-associated loci highlights ion channel pathways and biologically plausible candidate causal genes. Human Molecular Genetics, 25(6), 1247-1254. https://doi.org/10.1093/hmg/ddw007
Winkler, T. W., Justice, A. E., Graff, M., Barata, L., Feitosa, M. F., Chu, S., Czajkowski, J., Esko, T., Fall, T., Kilpelainen, T. O., Lu, Y., Magi, R., Mihailov, E., Pers, T. H., Rueger, S., Teumer, A., Ehret, G. B., Ferreira, T., Heard-Costa, N. L., ... MAGIC Consortium (2016). Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study (vol 11, e1005378, 2015). PLoS genetics, 12(6), [e1006166]. https://doi.org/10.1371/journal.pgen.1006166

2015

Franke, L., El Bannoudi, H., Jansen, D. T. S. L., Kok, K., Trynka, G., Diogo, D., Swertz, M., Fransen, K., Knevel, R., Gutierrez-Achury, J., Ärlestig, L., Greenberg, J. D., Kremer, J., Pappas, D. A., Kanterakis, A., Weersma, R. K., van der Helm-van Mil, A. H. M., Guryev, V., Rantapää-Dahlqvist, S., ... Zhernakova, A. (2016). Association analysis of copy numbers of FC-gamma receptor genes for rheumatoid arthritis and other immune-mediated phenotypes. European Journal of Human Genetics, 24(2), 263-270. https://doi.org/10.1038/ejhg.2015.95
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