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About us University College Groningen Research

Computational Biology and Cognition

The Bioinformatics Group at UCG investigates how molecular structure and gene-regulatory programs shape cell-state dynamics in health and disease. Its methods combine AI-driven molecular modeling with neuroimmunology. Amin’s work uses machine learning and quantum-mechanical calculations to understand metalloenzymes and other biomolecular systems. Medeiros-Furquim contributes expertise in microglia, the immune cells of the brain, and how epigenetics and immune memory are related to neuroinflammation (e.g., in Alzheimer’s disease, multiple sclerosis, and brain irradiation). Nannen adds AI, stochastic optimization, and agent-based simulation to bridge scales and build explanatory models from molecules to cell populations and tissues.

Publication Overview

2026

Corrêa, L. H., Braz-de-Melo, H. A., Santos, I. D. O., Bezerra, S. P., Manchine, J. P., Lago, N. C. S., Portacio-Santos, C. M. A., Almeida, R. D. N., Ribeiro, D. J. S., Medeiros-Furquim, T., Sant’ana, L. P., de Fragas, M. G., Lopes, F. T., Guerra, R. O., Câmara, N. O. S. O., Castro, M. S., Fontes, W., Zamboni, D. S., & Magalhães, K. G. (2026). Caspase-1/11 deficiency and cold exposure enhance the anti-tumor activity of brown adipose tissue secretome against breast cancer cells. Cancer & Metabolism, 14(1), Article 3. https://doi.org/10.1186/s40170-026-00422-9

2025

Amin, M., Hartmann, J. M., Samanta, A. K., & Küpper, J. (2025). Laser-Induced Alignment of Nanoparticles and Macromolecules for Coherent-Diffractive-Imaging Applications. Journal of the American Chemical Society, 147(9), 7445-7451. https://doi.org/10.1021/jacs.4c15679
Mohamed, A., Brooks, B. R., & Amin, M. (2025). Leveraging-Induced Polarization for Drug Discovery: Efficient IC50 Prediction Using Minimal Features. Journal of chemical information and modeling, 65(7), 3715-3722. https://doi.org/10.1021/acs.jcim.5c00076
Min, J., Ali, F., Brooks, B. R., Bruce, B. D., & Amin, M. (2025). Predicting Iron-Sulfur Cluster Redox Potentials: A Simple Model Derived from Protein Structures. ACS Omega, 10(15), 15790-15798. https://doi.org/10.1021/acsomega.5c01976
Otsuka, T., Karsilar, H., & van Rijn, H. (2025). Estimating the Mean: Behavioral and Neural Correlates of Summary Representations for Time Intervals. Journal of Cognitive Neuroscience, 37(9), 1562-1580. https://doi.org/10.1162/jocn_a_02327
Karsilar, H., Mathôt, S., & van Rijn, H. (2025). Stimuli are perceived as lasting longer when there is something bright on the screen. Attention, Perception, and Psychophysics, 87(6), 1948-1963. https://doi.org/10.3758/s13414-025-03120-8
Abad-Malo, D., Alvarado-Cando, O., & Karsilar, H. (2025). The Role of Spontaneous Eye Blinks in Temporal Perception: An Eye Tracking Study. Journal of Eye Movement Research, 18(6), Article 76. https://doi.org/10.3390/jemr18060076
Medeiros-Furquim, T., Miedema, A., Schilder, E., Brouwer, N., Holtman, I. R., Kooistra, S. M., & Eggen, B. J. L. (2025). Microglia endotoxin tolerance is retained after enforced repopulation. Brain, Behavior, and Immunity, 128, 512-528. https://doi.org/10.1016/j.bbi.2025.04.014

2024

Amin, M., Kaur, D., Brudvig, G. W., & Brooks, B. R. (2024). Mapping the Oxygens in the Oxygen-Evolving Complex of Photosystem II by Their Nucleophilicity Using Quantum Descriptors. Journal of Chemical Theory and Computation, 20(3), 1414–1422. https://doi.org/10.1021/acs.jctc.3c00926

2023

Kapuścińska, K., Dukała, Z., Doha, M., Ansari, E., Wang, J., Brudvig, G. W., Brooks, B., & Amin, M. (2024). Bridging the Coordination Chemistry of Small Compounds and Metalloproteins Using Machine Learning. Journal of chemical information and modeling, 64(7), 2586-2593. https://doi.org/10.1021/acs.jcim.3c01564
Ranepura, G. A., Mao, J., Vermaas, J. V., Wang, J., Gisriel, C. J., Wei, R. J., Ortiz-Soto, J., Uddin, M. R., Amin, M., Brudvig, G. W., & Gunner, M. R. (2023). Computing the Relative Affinity of Chlorophylls a and b to Light-Harvesting Complex II. Journal of Physical Chemistry B, 127(51), 10974-10986. https://doi.org/10.1021/acs.jpcb.3c06273
Abdelmouleh, M., Amin, M., Lalande, M., Schlathölter, T., & Poully, J.-C. (2023). Ionizing radiation induces cross-linking of two noncovalently-bound collagen mimetic peptide triple helices in the absence of molecular environment. PPCP : Physical Chemistry Chemical Physics, 25(42), 29249-29256. https://doi.org/10.1039/D3CP03264G
Gisriel, C. J., Shen, G., Flesher, D. A., Kurashov, V., Golbeck, J. H., Brudvig, G. W., Amin, M., & Bryant, D. A. (2023). Structure of a dimeric photosystem II complex from a cyanobacterium acclimated to far-red light. Journal of Biological Chemistry, 299(1), Article 102815. https://doi.org/10.1016/j.jbc.2022.102815
Medeiros-Furquim, T., Miedema, A., Schilder, E., Kooistra, S. M., & Eggen, B. J. L. (2023). Enforced microglia repopulation by CSF1R inhibition alters the microglia response to peripheral LPS but does not revert endotoxin tolerance. Glia.
Reiser, D., Sharipov, G. M., Hubel, G., Nannen, V., & Griepentrog, H. W. (2023). Development and Experimental Validation of an Agricultural Robotic Platform with High Traction and Low Compaction. Agriculture (Switzerland), 13(8), Article 1510. https://doi.org/10.3390/agriculture13081510
Nannen, V., & Bover, D. (2023). Lateral Stability of Vehicle with Interlocking Spikes. In C. B. Dreyer, & J. Littell (Eds.), Earth and Space 2022: Space Exploration, Utilization, Engineering, and Construction in Extreme Environments - Selected Papers from the 18th Biennial International Conference on Engineering, Science, Construction, and Operations in Challenging Environments (pp. 332-342). American Society of Civil Engineers (ASCE). https://doi.org/10.1061/9780784484470.031
Nannen, V., & Bover, D. (2023). Traction of Interlocking Spikes on a Granular Material. In C. B. Dreyer, & J. Littell (Eds.), Earth and Space 2022: Space Exploration, Utilization, Engineering, and Construction in Extreme Environments - Selected Papers from the 18th Biennial International Conference on Engineering, Science, Construction, and Operations in Challenging Environments (pp. 95-105). American Society of Civil Engineers (ASCE). https://doi.org/10.1061/9780784484470.009

2022

Ali, A., Basuni, M., Shams-Eldin, R., Pilz, L., Hashem, T., Heinle, M., Nefedov, A., Amin, M., Tsotsalas, M., Drazic, G., Hassanien, A., & Alkordi, M. H. (2023). Engineering of Molybdenum Sulfide Nanobunches on MWCNTs: Modulation of Active Sites and Electronic Conductivity via Controllable Solvothermal Deposition. ACS Applied Nano Materials, 6(5), 3627–3636. https://doi.org/10.1021/acsanm.2c05311
Amin, M. (2023). Predicting the oxidation states of Mn ions in the oxygen-evolving complex of photosystem II using supervised and unsupervised machine learning. Photosynthesis Research, 156, 89–100. https://doi.org/10.1007/s11120-022-00941-8
Ali, F., Shafaa, M. W., & Amin, M. (2022). Computational Approach for Probing Redox Potential for Iron-Sulfur Clusters in Photosystem I. Biology, 11(3), Article 362. https://doi.org/10.3390/biology11030362
Hashim, S., Farooq, S., Syriopoulos, E., Cremer, K. D. L. L., Vogt, A., de Jong, N., Aguado, V. L., Popescu, M., Mohamed, A. K., & Amin, M. (2022). Machine Learning Model for Predicting Number of COVID-19 Cases in Countries with Low Number of Tests. Open Bioinformatics Journal, 15, Article e187503622208290. https://doi.org/10.2174/18750362-v15-e2208290
Goher, S. S., Ali, F., & Amin, M. (2022). The Delta variant mutations in the receptor binding domain of SARS-CoV-2 show enhanced electrostatic interactions with the ACE2. Medicine in Drug Discovery, 13, Article 100114. https://doi.org/10.1016/j.medidd.2021.100114
Medeiros-Furquim, T., Ayoub, S., Johnson, L. J., Aprico, A., Nwoke, E., Binder, M. D., & Kilpatrick, T. J. (2022). Cladribine Treatment for MS Preserves the Differentiative Capacity of Subsequently Generated Monocytes, Whereas Its Administration In Vitro Acutely Influences Monocyte Differentiation but Not Microglial Activation. Frontiers in Immunology, 13, Article 678817. https://doi.org/10.3389/fimmu.2022.678817
Medeiros-Furquim, T., Miedema, A., Hukema, F., Schilder, E., Eggens-Meijer, E., Kooistra, S., & Eggen, B. (2022). Pharmacological microglia depletion followed by repopulation ameliorates recurrent cuprizone-induced demyelination. Multiple sclerosis journal.
Marmolejo-Garza, A., Medeiros-Furquim, T., Rao, R., Eggen, B. J. L., Boddeke, E., & Dolga, A. M. (2022). Transcriptomic and epigenomic landscapes of Alzheimer's disease evidence mitochondrial-related pathways. Biochimica et Biophysica Acta - Molecular Cell Research, 1869(10), Article 119326. https://doi.org/10.1016/j.bbamcr.2022.119326

2021

Welker, S., Amin, M., & Küpper, J. (2022). CMInject: Python framework for the numerical simulation of nanoparticle injection pipelines. Computer Physics Communications, 270, Article 108138. https://doi.org/10.1016/j.cpc.2021.108138
Semchonok, D. A., Mondal, J., Cooper, C. J., Schlum, K., Li, M., Amin, M., Sorzano, C. O. S., Ramírez-Aportela, E., Kastritis, P. L., Boekema, E. J., Guskov, A., & Bruce, B. D. (2022). Cryo-EM structure of a tetrameric photosystem I from Chroococcidiopsis TS-821, a thermophilic, unicellular, non-heterocyst-forming cyanobacterium. Plant Communications, 3(1), Article 100248. https://doi.org/10.1016/j.xplc.2021.100248
Ibrahim, M., & Amin, M. (2021). Predicting the Oxidation States of Mn ions in the Oxygen Evolving Complex of Photosystem II Using Supervised and Unsupervised Machine Learning. arXiv.
Ali, F., Kasry, A., & Amin, M. (2021). The new SARS-CoV-2 strain shows a stronger binding affinity to ACE2due to N501Y mutant. Medicine in Drug Discovery, 10, Article 100086. https://doi.org/10.1016/j.medidd.2021.100086
Ali, F., Kasry, A., & Amin, M. (2021). The New SARS-CoV-2 Strain Shows a Stronger Binding Affinity to ACE2 Due to N501Y Mutation. (ArXiv). arXiv.
Amin, M., Kaur, D., Gunner, M. R., & Brudvig, G. W. (2021). Toward understanding the S2-S3 transition in the Kok cycle of Photosystem II: Lessons from Sr-substituted structure. Inorganic Chemistry Communications, 133, Article 108890. https://doi.org/10.1016/j.inoche.2021.108890
Borggrewe, M., Kooistra, S. M., Wesseling, E. M., Gierschek, F. L., Brummer, M. L., Nowak, E. C., Medeiros-furquim, T., Otto, T. A., Lee, S. W., Noelle, R. J., Eggen, B. J. L., & Laman, J. D. (2021). VISTA regulates microglia homeostasis and myelin phagocytosis, and is associated with MS lesion pathology. Acta Neuropathologica Communications, 9(1), 91-109. Article 91. https://doi.org/10.1186/s40478-021-01186-7
Nannen, V., Bover, D., & Zöbel, D. (2021). Integrated Sensing and Earthmoving Vehicle for Lunar Landing Pad Construction. In Earth and Space 2021 ASCE. https://doi.org/10.1061/9780784483374.048
Nannen, V., & Bover, D. (2021). Interlocking Spikes for Extreme Mobility. In Earth and Space 2021 (pp. 521–530). ASCE. https://doi.org/10.1061/9780784483374.049

2020

Ali, F., Elserafy, M., Alkordi, M. H., & Amin, M. (2020). ACE2 coding variants in different populations and their potential impact on SARS-CoV-2 binding affinity. Biochemistry and Biophysics Reports, 24, Article 100798. https://doi.org/10.1016/j.bbrep.2020.100798
Amin, M., Sorour, M. K., & Kasry, A. (2020). Comparing the binding interactions in the receptor binding domains of SARS-CoV-2 and SARS-CoV. The Journal of Physical Chemistry Letters, 11(12), 4897–4900. https://doi.org/10.1021/acs.jpclett.0c01064
Samanta, A. K., Amin, M., Estillore, A. D., Roth, N., Worbs, L., Horke, D. A., & Küpper, J. (2020). Controlled beams of shock-frozen, isolated, biological and artificial nanoparticles. Structural dynamics, 7(2), Article 024304. https://doi.org/10.1063/4.0000004
Roth, N., Amin, M., Samanta, A. K., & Küpper, J. (2020). Microscopic force for aerosol transport. (ArXiv). arXiv. https://arxiv.org/abs/2006.10652
Ali, F., Medhat, S. W., & Amin, M. (2020). Probing redox potential for Iron sulfur clusters in photosystem I. (ArXiv). Cornell University Press. https://doi.org/10.48550/arXiv.2009.11681
Safy, M. E. A., Amin, M., Haikal, R. R., Elshazly, B., Wang, J., Wang, Y., Wöll, C., & Alkordi, M. H. (2020). Probing the Water Stability Limits and Degradation Pathways of Metal-Organic Frameworks (MOFs). Chemistry, 26(31), 7109-7117. https://doi.org/10.1002/chem.202000207
Amin, M., & Küpper, J. (2020). Variations in Proteins Dielectric Constants. Chemistryopen, 9(6), 691-694. https://doi.org/10.1002/open.202000108
Medeiros-Furquim, T. (2020). Interrogating The Influence Of The Multiple Sclerosis Modifying Drug Cladribine (2-Chlorodeoxyadenosine) Upon Primary Human Monocytes and Macrophages: T. Medeiros Furquim Mendonça1,2, S. Ayoub2, L. Johnson2, M. D. Binder2, T. J. Kilpatrick2*. Poster session presented at PACTRIMS 2019, Singapore. https://doi.org/10.1177/1352458520925277
Nannen, V., Bover, D., Reiser, D., & Zöbel, D. (2020). Reliability and Efficiency of Tractive Force Generation by the Interlock Drive System. engrXiv. https://doi.org/10.31224/osf.io/mh93n

2019

Etman, N., Said, A. M. A., Atia, K. S. R., Sultan, R., Hameed, M. F. O., Amin, M., & Obayya, S. S. A. (2019). Quantum Effects In Imaging Nano-Structures Using Photon-Induced Near-Field Electron Microscopy. Scientific Reports, 9, Article 6139. https://doi.org/10.1038/s41598-019-42624-w
Kaur, D., Szejgis, W., Mao, J., Amin, M., Reiss, K. M., Askerka, M., Cai, X., Khaniya, U., Zhang, Y., Brudvig, G. W., Batista, V. S., & Gunner, M. R. (2019). Relative stability of the S2 isomers of the oxygen evolving complex of photosystem II. Photosynthesis Research, 141(3), 331-341. https://doi.org/10.1007/s11120-019-00637-6
Amin, M., Samy, H., & Kuepper, J. (2019). Robust and Accurate Computational Estimation of the Polarizability Tensors of Macromolecules. JOURNAL OF PHYSICAL CHEMISTRY LETTERS, 10(11), 2938-2943. https://doi.org/10.1021/acs.jpclett.9b00963
Amin, M., Kaur, D., Yang, K. R., Wang, J., Mohamed, Z., Brudvig, G. W., Gunner, M. R., & Batista, V. (2019). Thermodynamics of the S2-to-S3 state transition of the oxygen-evolving complex of photosystem II. PPCP : Physical Chemistry Chemical Physics, 21(37), 20840-20848. https://doi.org/10.1039/c9cp02308a
Ibrahim, A. H., El-Mehalmey, W. A., Haikal, R. R., Safy, M. E. A., Amin, M., Shatla, H. R., Karakalos, S. G., & Alkordi, M. H. (2019). Tuning the Chemical Environment within the UiO-66-NH2 Nanocages for Charge-Dependent Contaminant Uptake and Selectivity. Inorganic Chemistry, 58(22), 15078-15087. https://doi.org/10.1021/acs.inorgchem.9b01611
Reiser, D., Nannen, V., Hubel, G., & Griepentrog, H. W. (2019). Design, modelling and control of a novel agricultural robot with interlock drive system. In 2019 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS) (pp. 5520-5525). Article 8968449 IEEE. https://doi.org/10.1109/iros40897.2019.8968449

2018

Amin, M., Mohamed, Z., El-Sayed, M., Samy, A., Sultan, A., Bassuoni, M., & Alkordi, M. H. (2018). Combined QM/MM and Monte Carlo study for redox leveling in Mn and Fe superoxide dismutase. Journal of biological inorganic chemistry, 23(2), 285-293. https://doi.org/10.1007/s00775-017-1530-8
Nannen, V., Bover, D., Reiser, D., & Zöbel, D. (2018). Motion Study of Spike Entering the Soil of the Interlock Drive System. In 21st ISTRO International Conference, Paris (pp. 405-406) https://doi.org/10.31224/osf.io/83794

2017

Mandal, M., Askerka, M., Banerjee, G., Amin, M., Brudvig, G. W., Batista, V. S., & Gunner, M. R. (2017). Characterization of ammonia binding to the second coordination shell of the oxygen-evolving complex of photosystem II. Dalton Transactions, 46(46), 16089-16095. https://doi.org/10.1039/c7dt03901h
Chierotti, M. R., Amin, M., Hassan, Y. S., Haikal, R. R., Garino, C., & Alkordi, M. H. (2017). Combined Solid-State NMR and Computational Approach for Probing the CO2 Binding Sites in a Porous-Organic Polymer. Journal of Physical Chemistry C, 121(16), 8850-8856. https://doi.org/10.1021/acs.jpcc.7b00660
Fuller, F. D., Gul, S., Chatterjee, R., Burgie, E. S., Young, I. D., Lebrette, H., Srinivas, V., Brewster, A. S., Michels-Clark, T., Clinger, J. A., Andi, B., Ibrahim, M., Pastor, E., de Lichtenberg, C., Hussein, R., Pollock, C. J., Zhang, M., Stan, C. A., Kroll, T., ... Yano, J. (2017). Drop-on-demand sample delivery for studying biocatalysts in action at X-ray free-electron lasers. Nature Methods, 14(4), 443-+. https://doi.org/10.1038/nmeth.4195
Haikal, R. R., Soliman, A. B., Amin, M., Karakalos, S. G., Hassan, Y. S., Elmansi, A. M., Hafez, I. H., Berber, M. R., Hassanien, A., & Alkordi, M. H. (2017). Synergism of carbon nanotubes and porous-organic polymers (POPs) in CO2 fixation: One-pot approach for bottom-up assembly of tunable heterogeneous catalyst. Applied catalysis b-Environmental, 207, 347-357. https://doi.org/10.1016/j.apcatb.2017.02.009
Amin, M., Askerka, M., Batista, V. S., Brudvig, G. W., & Gunner, M. R. (2017). X-ray Free Electron Laser Radiation Damage through the S-State Cycle of the Oxygen-Evolving Complex of Photosystem II. Journal of Physical Chemistry B, 121(40), 9382-9388. https://doi.org/10.1021/acs.jpcb.7b08371
Nannen, V., Bover, D., & Zöbel, D. (2017). A Novel Traction Mechanism Based on Retractable Crampons to Minimize Soil Compaction and Reduce Energy Consumption.

2016

Amin, M., Pokhrel, R., Brudvig, G. W., Badawi, A., & Obayya, S. S. A. (2016). Effect of Chloride Depletion on the Magnetic Properties and the Redox Leveling of the Oxygen-Evolving Complex in Photosystem II. The Journal of Physical Chemistry B, 120(18), 4243-4248. https://doi.org/10.1021/acs.jpcb.6b03545
Amin, M., Badawi, A., & Obayya, S. S. (2016). Radiation Damage in XFEL: Case study from the oxygen-evolving complex of Photosystem II. Scientific Reports, 6, Article 36492. https://doi.org/10.1038/srep36492
Nannen, V., Bover, D., Zöbel, D., McKenzie, B. M., & Ben Avraham, M. (2016). UTOPUS: A Novel Traction Mechanism to Minimize Soil Compaction and Reduce Energy Consumption. engrXiv. https://doi.org/10.31224/osf.io/wtqbn
Nannen, V., Bover, D., Zöbel, D., Parma, F., Marascio, K., & McKenzie, B. M. (2016). UTOPUS Traction Technology: A New Method for Planetary Exploration of Steep and Difficult Terrain. engrXiv. https://doi.org/10.31224/osf.io/bgznf

2015

Amin, M., Vogt, L., Szejgis, W., Vassiliev, S., Brudvig, G. W., Bruce, D., & Gunner, M. R. (2015). Proton-Coupled Electron Transfer During the S-State Transitions of the Oxygen-Evolving Complex of Photosystem II. Journal of Physical Chemistry B, 119(24), 7366-7377. https://doi.org/10.1021/jp510948e
Bover Trovat, D., Nannen, V., & Ramirez Camps, G. (2015). Apparatus and Method to Determine Ground Properties by Traction Anchors and Sensors. (Patent No. US9945832). United States Patent and Trademark Office.

2014

Sauter, N., Brewster, A., Hattne, J., Amin, M., Kern, J., Yano, J., & Yachandra, V. (2014). Improving the accuracy for Photosystem II and other XFEL structures. Acta crystallographica a-Foundation and advances, 70, C571-C571. https://doi.org/10.1107/S2053273314094285

2013

Amin, M., Vogt, L., Vassiliev, S., Rivalta, I., Sultan, M. M., Bruce, D., Brudvig, G. W., Batista, V. S., & Gunner, M. R. (2013). Electrostatic Effects on Proton Coupled Electron Transfer in Oxomanganese Complexes Inspired by the Oxygen-Evolving Complex of Photosystem II. Journal of Physical Chemistry B, 117(20), 6217-6226. https://doi.org/10.1021/jp403321b
Gunner, M. R., Amin, M., Zhu, X., & Lu, J. (2013). Molecular mechanisms for generating transmembrane proton gradients. Biochimica et Biophysica Acta, 1827(8-9), 892-913. https://doi.org/10.1016/j.bbabio.2013.03.001
Nannen, V., & Oliver, G. (2013). Grid-Based Spatial Keypoint Selection for Real Time Visual Odometry. In 2nd International Conference on Pattern Recognition Applications and Methods, ICPRAM'13 (pp. 586-589). SciTePress. https://doi.org/10.5220/0004270005860589
Nannen, V., Eiben, A. E., & van den Bergh, JCJM. (2013). Impact of environmental dynamics on economic evolution: A stylized agent-based policy analysis. Technological Forecasting and Social Change, 80(2), 329-350. https://doi.org/10.1016/j.techfore.2012.08.013
Nannen, V., & Bover, D. (2013). Technical Background to the Autonomous Self-Actuated Tillage Implement. United States Patent and Trademark Office. https://sedewa.com/ref/Technical_Background_2013.pdf

2012

Nannen, V., & Oliver, G. (2012). Optimal Number of Image Keypoints for Real Time Visual Odometry. In 3rd IFAC Workshop on Navigation, Guidance and Control of Underwater Vehicles, NGCUV 2012 (pp. 331-336). Elsevier. https://doi.org/10.3182/20120410-3-PT-4028.00055
Prats, M., Ribas, D., Palomeras, N., García, J. C., Nannen, V., Wirth, S., Fernández, J. J., Beltrán, J. P., Campos, R., Ridao, P., Sanz, P. J., Oliver, G., Carreras, M., Gracias, N., Marín, R., & Ortiz, A. (2012). Reconfigurable AUV for intervention missions: A case study on underwater object recovery. Intelligent Service Robotics, 5, 19–31. https://doi.org/10.1007/s11370-011-0101-z

2011

Rivalta, I., Amin, M., Luber, S., Vassiliev, S., Pokhrel, R., Umena, Y., Kawakami, K., Shen, J.-R., Kamiya, N., Bruce, D., Brudvig, G. W., Gunner, M. R., & Batista, V. S. (2011). Structural-Functional Role of Chloride in Photosystem II. Biochemistry, 50(29), 6312-6315. https://doi.org/10.1021/bi200685w

2010

Nannen, V. (2010). A Short Introduction to Kolmogorov Complexity. (ArXiv). arXiv. https://doi.org/10.48550/arXiv.1005.2400
Nannen, V., & Bergh, J. C. J. M. V. D. (2010). Policy Instruments for Evolution of Bounded Rationality: Application to Climate-Energy Problems. Technological Forecasting & Social Change, 77(1), 76-93. https://doi.org/10.1016/j.techfore.2009.05.003

2008

Nannen, V., Smit, S. K., & Eiben, A. E. (2008). Costs and Benefits of Tuning Parameters of Evolutionary Algorithms. In G. Rudolph, T. Jansen, N. Beume, S. Lucas, & C. Poloni (Eds.), Parallel Problem Solving from Nature, PPSN X (pp. 528–538). (Lecture Notes in Computer Science ; Vol. 5199). Springer. https://doi.org/10.1007/978-3-540-87700-4_53

2007

Nannen, V., & Eiben, A. E. (2007). Efficient relevance estimation and value calibration of evolutionary algorithm parameters. In IEEE Congress on Evolutionary Computation, CEC'07 (pp. 103-110). IEEE. https://doi.org/10.1109/CEC.2007.4424460
De Landgraaf, W. A., Eiben, A. E., & Nannen, V. (2007). Parameter calibration using meta-algorithms. In 2007 IEEE Congress on Evolutionary Computation (pp. 71-78). Article 4424456 (2007 IEEE Congress on Evolutionary Computation, CEC 2007). IEEE. https://doi.org/10.1109/CEC.2007.4424456
Nannen, V., & Eiben, A. E. (2007). Relevance estimation and value calibration of evolutionary algorithm parameters. In 20th International Joint Conference on Artificial Intelligence (pp. 975-980). (IJCAI International Joint Conference on Artificial Intelligence). IJCAI. https://www.ijcai.org/Proceedings/07/Papers/157.pdf
Nannen, V., & Eiben, A. E. (2007). Variance reduction in meta-EDA. In 9th Annual Genetic and Evolutionary Computation Conference, GECCO 2007 (pp. 627). ACM Press Digital Library. https://doi.org/10.1145/1276958.1277087

2006

Nannen, V., & Eiben, A. E. (2006). A method for parameter calibration and relevance estimation in evolutionary algorithms. In M. Cattolico (Ed.), GECCO 2006 - Proceedings of the 8th annual conference on Genetic and evolutionary computation (pp. 183-190). ACM Press Digital Library. https://doi.org/10.1145/1143997.1144029
Nannen, V., & Eiben, A. E. (2006). Generality of results obtained by the parameter calibration and relevance estimation method. In Parallel Problem Solving from Nature, PPSN IX, Workshop on Empirical Methods for the Analysis of Algorithms EMAA 2006 https://www.imada.sdu.dk/u/marco/EMAA/Papers/EMAA06-nannen.pdf
Last modified:24 February 2026 3.54 p.m.