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About us Practical matters How to find us prof. dr. P.C.A. (Patrick) van der Wel

prof. dr. P.C.A. (Patrick) van der Wel

Assoc. Professor Solid State NMR Spectroscopy

Faculty of Science and Engineering

Telephone:

+31 50 36 32683 (Phone)

Anja Onstwedder-Reiling:

+31 50 36 33385 (Secr.)

j.j.onstwedder rug.nl

E-mail:

p.c.a.van.der.wel rug.nl

Homepage ORCID Research Portal

Publications

Surface-Binding to Cardiolipin Nanodomains Triggers Cytochrome c Pro-apoptotic Peroxidase Activity via Localized Dynamics

Li, M., Mandal, A., Tyurin, V. A., DeLucia, M., Ahn, J., Kagan, V. E. & van der Wel, P. C. A., 7-May-2019, In: Structure. 27, 5, p. 806-815.e4 15 p.

Research output: Contribution to journal › Article › Academic › peer-review

Structural fingerprinting of protein aggregates by DNP-enhanced solid-state NMR at natural isotopic abundance

Smith, A. N., Märker, K., Piretra, T., Boatz, J. C., Matlahov, I., Kodali, R. B., Hediger, S., van der Wel, P. C. A. & De Paëpe, G., 7-Nov-2018, In: Journal of the American Chemical Society. 140, 44, p. 14576-14580 5 p.

Research output: Contribution to journal › Article › Academic › peer-review

New applications of solid-state NMR in structural biology

van der Wel, P. C. A., 20-Apr-2018, In: Emerging topics in life sciences. 2, 1, p. 57-67 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

Insights into protein misfolding and aggregation enabled by solid-state NMR spectroscopy

van der Wel, P. C. A., Nov-2017, In: Solid state nuclear magnetic resonance. 88, p. 1-14 14 p.

Research output: Contribution to journal › Review article › peer-review

Fibril polymorphism affects immobilized non-amyloid flanking domains of huntingtin exon1 rather than its polyglutamine core

Lin, H-K., Boatz, J. C., Krabbendam, I. E., Kodali, R., Hou, Z., Wetzel, R., Dolga, A. M., Poirier, M. A. & van der Wel, P. C. A., 24-May-2017, In: Nature Communications. 8, 12 p., 15462.

Research output: Contribution to journal › Article › Academic › peer-review

Cataract-associated P23T γD-crystallin retains a native-like fold in amorphous-looking aggregates formed at physiological pH

Boatz, J. C., Whitley, M. J., Li, M., Gronenborn, A. M. & van der Wel, P. C. A., 5-May-2017, In: Nature Communications. 8, p. 15137

Research output: Contribution to journal › Article › Academic › peer-review

Peptide-Directed Assembly of Single-Helical Gold Nanoparticle Superstructures Exhibiting Intense Chiroptical Activity

Merg, A. D., Boatz, J. C., Mandal, A., Zhao, G., Mokashi-Punekar, S., Liu, C., Wang, X., Zhang, P., van der Wel, P. C. A. & Rosi, N. L., 19-Oct-2016, In: Journal of the American Chemical Society. 138, 41, p. 13655-13663

Research output: Contribution to journal › Article › Academic › peer-review

Huntingtin exon 1 fibrils feature an interdigitated β-hairpin-based polyglutamine core

Hoop, C. L., Lin, H. K., Kar, K., Magyarfalvi, G., Lamley, J. M., Boatz, J. C., Mandal, A., Lewandowski, J. R., Wetzel, R. & Van Der Wel, P. C. A., 9-Feb-2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 6, p. 1546-1551 6 p.

Research output: Contribution to journal › Article › Academic › peer-review

Structural Changes and Proapoptotic Peroxidase Activity of Cardiolipin-Bound Mitochondrial Cytochrome c

Mandal, A., Hoop, C. L., DeLucia, M., Kodali, R., Kagan, V. E., Ahn, J. & van der Wel, P. C. A., 3-Nov-2015, In: Biophysical Journal. 109, 9, p. 1873-84 12 p.

Research output: Contribution to journal › Article › Academic › peer-review

Anomalous peroxidase activity of cytochrome c is the primary pathogenic target in Barth syndrome

Kagan, V. E., Tyurina, Y. Y., Mikulska-Ruminska, K., Damschroder, D., Vieira Neto, E., Lasorsa, A., Kapralov, A. A., Tyurin, V. A., Amoscato, A. A., Samovich, S. N., Souryavong, A. B., Dar, H. H., Ramim, A., Liang, Z., Lazcano, P., Ji, J., Schmidtke, M. W., Kiselyov, K., Korkmaz, A., Vladimirov, G. K., & 15 othersArtyukhova, M. A., Rampratap, P., Cole, L. K., Niyatie, A., Baker, E-K., Peterson, J., Hatch, G. M., Atkinson, J., Vockley, J., Kühn, B., Wessells, R., van der Wel, P. C. A., Bahar, I., Bayir, H. & Greenberg, M. L., 23-Nov-2023, (E-pub ahead of print) In: Nature Metabolism. 35 p.

Research output: Contribution to journal › Article › Academic › peer-review

All (85) publications

Press/media

De Twitterende wetenschapper: Patrick van der Wel over zijn onderzoek naar onbekende ziektes

Patrick van der Wel

23/06/2022

Press/Media: Public Engagement Activities › Popular

NL_Wetenschap Twitter account

Patrick van der Wel

23/06/2022

Press/Media: Public Engagement Activities › Popular

'세포 자살' 신호는 어떻게 미토콘드리아에 전달될까

Patrick Christiaan Alexander van der Wel

08/07/2021

Press/Media: Expert Comment › Academic

Scientists unravel how cell death is initiated on a molecular level

Patrick Christiaan Alexander van der Wel

07/07/2021

Press/Media: Expert Comment › Popular

How an unfolding protein can induce programmed cell death

Patrick Christiaan Alexander van der Wel

07/07/2021

Press/Media: Expert Comment › Popular

How An Unfolding Protein Can Induce Programmed Cell Death? (Biology)

Patrick Christiaan Alexander van der Wel

06/07/2021

Press/Media: Expert Comment › Popular

How an unfolding protein can induce programmed cell death

Patrick Christiaan Alexander van der Wel

06/07/2021

Press/Media: Expert Comment › Popular

Protein With ‘Switch’ Sensitive to Clumping May Aid in Treating Disease

Patrick Christiaan Alexander van der Wel

20/04/2021

Press/Media: Other › Popular

Revealed protein structure could aid in Huntington’s disease treatment development

Patrick Christiaan Alexander van der Wel

16/02/2021

Press/Media: Expert Comment › Popular

Study reveals the structure of heat shock proteins that could treat Huntington's disease

Patrick Christiaan Alexander van der Wel

15/02/2021

Press/Media: Expert Comment › Popular

All (11) press/media

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