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Over ons Praktische zaken Waar vindt u ons G. (Giovanni) Maglia, Prof

G. (Giovanni) Maglia, Prof

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Faculteit Science and Engineering

Telefoon:

E-mail:

giovanni.maglia rug.nl

Homepage ORCID Research Portal

Research interests

The main focus of our group is on the chemistry and biophysics of nanopores. We are engineering, modifying and redesigning these protein systems for applications in NanoBioTechnology and Single-Molecule Biophysics.

We are using biological nanopores in:

• Single-molecule enzymology

• Single-molecule sensing and DNA analysis

• Protein components for nanomachines

Research Group Webpage -Google pages

Research Group RUG Webpage

Publicaties

Balancing Permeability and Stability: A Study of Hybrid Membranes for Synthetic Cells Using Lipids and PBd-b-PEO Block Copolymers

Presutti, C., Vreeker, E., Sasidharan, S., Ferdinando, Z., Stuart, M., Juhaniewicz-Dębińska, J., Maglia, G., Roos, W. H. & Poolman, B., 8-apr.-2025, (E-pub ahead of print) In: Biomacromolecules. 14 blz., 4c01651.

Onderzoeksoutput › › peer review

Nanopore-Functionalized Hybrid Lipid-Block Copolymer Membranes Allow Efficient Single-Molecule Sampling and Stable Sensing of Human Serum

Vreeker, E., Grünewald, F., van der Heide, N. J., Bonini, A., Marrink, S. J., Tych, K. K. & Maglia, G., apr.-2025, In: Advanced materials. 37, 15, 15 blz., e2418462.

Onderzoeksoutput › › peer review

Nanopores with an Engineered Selective Entropic Gate Detect Proteins at Nanomolar Concentration in Complex Biological Sample

Straathof, S., Di Muccio, G. & Maglia, G., 7-mei-2025, In: Journal of the American Chemical Society. 147, 18, blz. 15050-15065 16 blz., 4c17147.

Onderzoeksoutput › › peer review

Toward single-molecule protein sequencing using nanopores

Lu, C., Bonini, A., Viel, J. H. & Maglia, G., 17-mrt.-2025, In: Nature Biotechnology. 43, 3, blz. 312-322 11 blz.

Onderzoeksoutput › peer review

Allostery can convert binding free energies into concerted domain motions in enzymes

Galenkamp, N. S., Zernia, S., Van Oppen, Y. B., van den Noort, M., Argeitis, A. M. & Maglia, G., 22-nov.-2024, In: Nature Communications. 15, 1, 13 blz., 10109.

Onderzoeksoutput › › peer review

Blobs form during the single-file transport of proteins across nanopores

Sauciuc, A., Whittaker, J., Tadema, M., Tych, K., Guskov, A. & Maglia, G., 12-sep.-2024, In: Proceedings of the National Academy of Sciences. 121, 38, 10 blz., e2405018121.

Onderzoeksoutput › › peer review

Controlled Translocation of Proteins through a Biological Nanopore for Single-Protein Fingerprint Identification

Sauciuc, A. & Maglia, G., 24-okt.-2024, In: Nano Letters. 24, blz. 14118–14124 7 blz., 4c04510.

Onderzoeksoutput › › peer review

Controlling Electroosmosis in Nanopores Without Altering the Nanopore Sensing Region

Baldelli, M., Muccio, G. D., Sauciuc, A., Rocca, B. M. D., Viola, F., Balme, S., Bonini, A., Maglia, G. & Chinappi, M., 15-aug.-2024, In: Advanced materials. 36, 33, 21 blz., 2401761.

Onderzoeksoutput › › peer review

Engineered nanopores for exopeptidase protein sequencing

Bonini, A., Sauciuc, A. & Maglia, G., jan.-2024, In: Nature Methods. 21, blz. 16-17 2 blz.

Onderzoeksoutput › › peer review

Large conical nanopores and uses thereof in analyte sensing

Maglia, G. (Uitvinder), Yelleswarapu, M. (Uitvinder), Wloka, C. (Uitvinder) & Straathof, S. (Uitvinder), 3-okt.-2024, Octrooi Nr. WO2024205413, 2-apr.-2024, Prioriteitsdatum 30-mrt.-2023

Onderzoeksoutput

Alle (110) publicaties

Pers/media

Current Approaches to Protein Sequencing

Maglia, G.

05/04/2024

Pers / media: Expert Comment ›

ERC Proof of Concept subsidie om monitoren van patiënten met hartfalen te verbeteren

Maglia, G.

18/01/2024

Pers / media: Activiteiten met een maatschappelijk belang ›

ERC Proof of Concept Grant to improve monitoring heart failure patients

Maglia, G.

18/01/2024

Pers / media: Activiteiten met een maatschappelijk belang ›

Breakthrough: Protein Triumphantly Transmitted Through Nanopore!

Maglia, G.

19/09/2023

Pers / media: Expert Comment ›

Protein Successfully Transported Through a Nanopore

Maglia, G.

19/09/2023

Pers / media: Expert Comment ›

Engineered Nanopore Translocates Full Length Proteins

Maglia, G.

19/09/2023

Pers / media: Expert Comment ›

The Final Piece Required for Easy Protein Sequencing

Maglia, G.

19/09/2023

Pers / media: Expert Comment ›

The missing link to make easy protein sequencing possible?

Maglia, G.

18/09/2023 → 19/09/2023

Pers / media: Expert Comment ›

Is There a Missing Link that Can Simplify Protein Sequencing?

Maglia, G.

18/09/2023

Pers / media: Expert Comment ›

Missing Link Discovered for Simplified Protein Sequencing

Maglia, G.

18/09/2023

Pers / media: Expert Comment ›

Alle (64) pers/media

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