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ResearchBiomolecular X-ray Crystallography Group

Publication list

2019

Zhang, X., Leemhuis, H., Janeček, Š., Martinovičová, M., Pijning, T., & van der Maarel, M. J. E. C. (2019). Identification of Thermotoga maritima MSB8 GH57 α-amylase AmyC as a glycogen-branching enzyme with high hydrolytic activity. Applied Microbiology and Biotechnology, 103, 6141–6151. https://doi.org/10.1007/s00253-019-09938-1
Biewenga, L., Thangavelu, S., Kunzendorf, A., Van Der Meer, J., Pijning, T., Tepper, P., ... Poelarends, G. J. (2019). Enantioselective Synthesis of Pharmaceutically Active γ-Aminobutyric Acids Using a Tailor-Made Artificial Michaelase in One-Pot Cascade Reactions. ACS Catalysis, 9, 1503-1513. https://doi.org/10.1021/acscatal.8b04299
Zhang, X., Leemhuis, R., van der Maarel, M., Pijning, T., Janecek, S., & Martinovicova, M. (2019). Identification of Thermotoga maritima SMB8 GH57 α-amylase AmyC as a glycogen branching enzyme with high hydrolytic activity. Manuscript submitted for publication.
Garaeva, A. A., Guskov, A., Slotboom, D. J., & Paulino, C. (2019). A one-gate elevator mechanism for the human neutral amino acid transporter ASCT2. Nature Communications, 10, [3427]. https://doi.org/10.1038/s41467-019-11363-x
Ejby, M., Guskov, A., Pichler, M. J., Zanten, G. C., Schoof, E., Saburi, W., ... Abou Hachem, M. (2019). Two binding proteins of the ABC transporter that confers growth of Bifidobacterium animalis subsp. lactis ATCC27673 on β-mannan possess distinct manno-oligosaccharide binding profiles. Molecular Microbiology, 112(1), 114-130. [14257]. https://doi.org/10.1111/mmi.14257
Arkhipova, V. I., Trinco, G., Thijs, E., Jensen, S., Slotboom, D., & Guskov, A. (2019). Binding and transport of D-aspartate by the glutamate transporter homologue GltTk. eLife, 8, [e45286]. https://doi.org/10.7554/eLife.45286

2018

Pham, H., Pijning, T., Dijkhuizen, L., & van Leeuwen, S. S. (2018). Mutational Analysis of the Role of the Glucansucrase Gtf180-Delta N Active Site Residues in Product and Linkage Specificity with Lactose as Acceptor Substrate. Journal of Agricultural and Food Chemistry, 66(47), 12544-12554. [acs.jafc.8b04486]. https://doi.org/10.1021/acs.jafc.8b04486
Gangoiti Muñecas, J., van Leeuwen, S. S., Pijning, T., Dijkhuizen, L., Vafeiadi, C., & Duboux, S. (2018). Branched alpha glucans. (Patent No. WO2018167032).
Zhang, F., Liu, H., Zhang, T., Pijning, T., Yu, L., Zhang, W., ... Meng, X. (2018). Biochemical and genetic characterization of fungal proline hydroxylase in echinocandin biosynthesis. Applied Microbiology and Biotechnology, 102(18), 7877-7890. https://doi.org/10.1007/s00253-018-9179-y
Meng, X., Gangoiti, J., Wang, X., Grijpstra, P., van Leeuwen, S. S., Pijning, T., & Dijkhuizen, L. (2018). Biochemical characterization of a GH70 protein from Lactobacillus kunkeei DSM 12361 with two catalytic domains involving branching sucrase activity. Applied Microbiology and Biotechnology, 102(18), 7935-7950. https://doi.org/10.1007/s00253-018-9236-6
Meng, X., Gangoiti, J., de Kok, N., van Leeuwen, S. S., Pijning, T., & Dijkhuizen, L. (2018). Biochemical characterization of two GH70 family 4,6-α-glucanotransferases with distinct product specificity from Lactobacillus aviarius subsp. aviarius DSM 20655. Food Chemistry, 253, 236-246. [j.foodchem.2018.01.154]. https://doi.org/10.1016/j.foodchem.2018.01.154
Rempel, S., Colucci, E., Gier, J-W. D., Guskov, A., & Slotboom, D. (2018). Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM. Nature Communications, 9(1), [3038]. https://doi.org/10.1038/s41467-018-05441-9
Garaeva, A., Oostergetel, G., Gati, C., Guskov, A., Batista Paulino, C., & Slotboom, D. (2018). Cryo-EM structure of the human neutral amino acid transporter ASCT2. Nature Structural & Molecular Biology, 25, 515-521. https://doi.org/10.1038/s41594-018-0076-y
Luís da Silva Santos Guimarães, J. A., Rempel, S., Mous, S. T. M., Tambascia Pereira, C., ter Beek, J., Gier, J-W. D., ... Slotboom, D. (2018). Functional and structural characterization of an ECF-type ABC transporter for vitamin B12. eLife, 7, [e35828]. https://doi.org/10.7554/eLife.35828

2017

Gangoiti, J., Pijning, T., & Dijkhuizen, L. (2018). Biotechnological potential of novel glycoside hydrolase family 70 enzymes synthesizing α-glucans from starch and sucrose. Biotechnology Advances, 36, 196-207. https://doi.org/10.1016/j.biotechadv.2017.11.001
Franken, L., Oostergetel, G., Pijning, T., Puri, P., Arkhipova, V. I., Boekema, E., ... Guskov, A. (2017). A general mechanism of ribosome dimerization revealed by single-particle cryo-electron microscopy. Nature Communications, 8, [722]. https://doi.org/10.1038/s41467-017-00718-x
Gangoiti, J., van Leeuwen, S. S., Meng, X., Duboux, S., Vafiadi, C., Pijning, T., & Dijkhuizen, L. (2017). Mining novel starch-converting Glycoside Hydrolase 70 enzymes from the Nestlé Culture Collection genome database: The Lactobacillus reuteri NCC 2613 GtfB. Scientific Reports, 7(1), [9947]. https://doi.org/10.1038/s41598-017-07190-z
Meng, X., Pijning, T., Tietema, M., Dobruchowska, J. M., Yin, H., Gerwig, G. J., ... Dijkhuizen, L. (2017). Characterization of the glucansucrase GTF180 W1065 mutant enzymes producing polysaccharides and oligosaccharides with altered linkage composition. Food Chemistry, 217, 81-90. https://doi.org/10.1016/j.foodchem.2016.08.087
Yin, H., Pijning, T., Meng, X., Dijkhuizen, L., & van Leeuwen, S. S. (2017). Engineering of the Bacillus circulans β-galactosidase product specificity. Biochemistry, 56(5), 704-711. https://doi.org/10.1021/acs.biochem.7b00032
Gangoiti Muñecas, J., van Leeuwen, S. S., Gerwig, G. J., Duboux, S., Vafiadi, C., Pijning, T., & Dijkhuizen, L. (2017). 4,3-α-Glucanotransferase, a novel reaction specificity in glycoside hydrolase family 70 and clan GH-H. Scientific Reports, 7, 1-15. [39761]. https://doi.org/10.1038/srep39761
Sarian, F. D., Janeček, Š., Pijning, T., Ihsanawati, Nurachman, Z., Radjasa, O. K., ... van der Maarel, M. J. E. C. (2017). A new group of glycoside hydrolase family 13 α-amylases with an aberrant catalytic triad. Scientific Reports, 7, [44230]. https://doi.org/10.1038/srep44230
Yin, H., Pijning, T., Meng, X., Dijkhuizen, L., & van Leeuwen, S. S. (2017). Biochemical characterization of the functional roles of residues in the active site of the β-galactosidase from Bacillus circulans ATCC 31382. Biochemistry, 56(24), 3109-3118. https://doi.org/10.1021/acs.biochem.7b00207
Arkhipova, V. I., Guskov, A., & Slotboom, D. (2017). Analysis of the quality of crystallographic data and the limitations of structural models. The Journal of General Physiology, 149(12). https://doi.org/10.1085/jgp.201711852
Gati, C., Stetsenko, A., Slotboom, D., Scheres, S., & Guskov, A. (2017). The structural basis of proton driven zinc transport by ZntB. Nature Communications, 8, [1313]. https://doi.org/10.1038/s41467-017-01483-7
Stetsenko, A., & Guskov, A. (2017). An Overview of the Top Ten Detergents Used for Membrane Protein Crystallization. Crystals, 7(7), 1-16. [197]. https://doi.org/10.3390/cryst7070197

2016

Bai, Y., Gangoiti , J., Dijkstra, B. W., Dijkhuizen, L., & Pijning, T. (2017). Crystal Structure of 4,6-α-Glucanotransferase Supports Diet-Driven Evolution of GH70 Enzymes from α-Amylases in Oral Bacteria. Structure, 25(2), 231-242. https://doi.org/10.1016/j.str.2016.11.023
Pijning, T., Bai, Y., Gangoiti Muñecas, J., & Dijkhuizen, L. (2016). Crystal Structure of a 4,6-α-Glucanotransferase Supports Diet-Driven Evolution of GH70 Enzymes from α-Amylases in Oral Bacteria. Poster session presented at ALAMY, Smolenice, Slovakia.
Meng, X., Gangoiti, J., Bai, Y., Pijning, T., Van Leeuwen, S. S., & Dijkhuizen, L. (2016). Structure-function relationships of family GH70 glucansucrase and 4,6-α-glucanotransferase enzymes, and their evolutionary relationships with family GH13 enzymes. Cellular and molecular life sciences, 73(14), 2681-2706. https://doi.org/10.1007/s00018-016-2245-7
Bai, Y., Böger, M., van der Kaaij, R. M., Woortman, A. J. J., Pijning, T., van Leeuwen, S. S., ... Dijkhuizen, L. (2016). Lactobacillus reuteri strains convert starch and maltodextrins into homo-exopolysaccharides using an extracellular and cell-associated 4,6-α-glucanotransferase. Journal of Agricultural and Food Chemistry, 64(14), 2941-2952. https://doi.org/10.1021/acs.jafc.6b00714
Meng, X., Pijning, T., Dobruchowska, J. M., Yin, H., Gerwig, G. J., & Dijkhuizen, L. (2016). Structural determinants of alternating (α1 → 4) and (α1 → 6) linkage specificity in reuteransucrase of Lactobacillus reuteri. Scientific Reports, 6, [35261]. https://doi.org/10.1038/srep35261
Swier, L. J. Y. M., Guskov, A., & Slotboom, D. J. (2016). Structural insight in the toppling mechanism of an energy-coupling factor transporter. Nature Communications, 7, 1-11. [11072]. https://doi.org/10.1038/ncomms11072
Jähme, M., Guskov, A., & Slotboom, D. J. (2016). Pnu Transporters: Ain't They SWEET? Trends in Biochemical Sciences, 41(2), 117-118. https://doi.org/10.1016/j.tibs.2015.11.013
Guskov, A., & Slotboom, D. (2016). Size exclusion chromatography with multi-angle laser light scattering (SEC-MALLS) to determine protein oligomeric states. In E. Pebay-Peyroula, H. Nury, F. Parcy, R. W. H. Ruigrok, C. Ziegler, & L. F. Cugliandolo (Eds.), From molecules to living organisms: an interplay between biology and physics: Lecture Notes of the Les Houches School of Physics: Volume 102, July 2014 (pp. 169-183). [6] (Lecture Notes of the Les Houches School of Physics; Vol. 102). Oxford University Press.
Guskov, A., Jensen, S., Faustino, I., Marrink, S. J., & Slotboom, D. J. (2016). Coupled binding mechanism of three sodium ions and aspartate in the glutamate transporter homologue GltTk. Nature Communications, 7, 1-6. [13420]. https://doi.org/10.1038/ncomms13420

2015

Meng, X., Dobruchowska, J. M., Pijning, T., Gerwig, G. J., & Dijkhuizen, L. (2016). Synthesis of New Hyper-Branched α-Glucans from Sucrose by Lactobacillus reuteri 180 Glucansucrase Mutants. Journal of Agricultural and Food Chemistry, 64(2), 433-442. https://doi.org/10.1021/acs.jafc.5b05161
Meng, X., Pijning, T., Dobruchowska, J. M., Gerwig, G. J., & Dijkhuizen, L. (2015). Characterization of the functional roles of amino acid residues in acceptor binding subsite +1 in the active site of the glucansucrase GTF180 enzyme of Lactobacillus reuteri 180. The Journal of Biological Chemistry, 290(50), 30131-30141. https://doi.org/10.1074/jbc.M115.687558
Gangoiti, J., Pijning, T., & Dijkhuizen, L. (2015). The Exiguobacterium sibiricum 255-15 GtfC enzyme representing a novel glycoside hydrolase 70 subfamily of 4,6-α-glucanotransferase enzymes. Applied and environmental microbiology, 82(2), 756-766. [AEM.03420-15]. https://doi.org/10.1128/AEM.03420-15
Bai, Y., van der Kaaij, R. M., Leemhuis, H., Pijning, T., van Leeuwen, S. S., Jin, Z., & Dijkhuizen, L. (2015). Biochemical characterization of Lactobacillus reuteri Glycoside Hydrolase family 70 GTFB type of 4,6-α-Glucanotransferase enzymes that synthesize soluble dietary starch fibers. Applied and environmental microbiology, 81(20), 7223-7232. https://doi.org/10.1128/AEM.01860-15
Meng, X., Dobruchowska, J. M., Pijning, T., Gerwig, G. J., Kamerling, J. P., & Dijkhuizen, L. (2015). Truncation of domain V of the multidomain glucansucrase GTF180 of Lactobacillus reuteri 180 heavily impairs its polysaccharide-synthesizing ability. Applied Microbiology and Biotechnology, 99(14), 5885-5894. https://doi.org/10.1007/s00253-014-6361-8
Swier, L. J. Y. M., Monjas, L., Guskov, A., de Voogd, A. R., Erkens, G. B., Slotboom, D. J., & Hirsch, A. K. H. (2015). Structure-Based Design of Potent Small-Molecule Binders to the S-Component of the ECF Transporter for Thiamine. ChemBioChem, 16(5), 819-826. https://doi.org/10.1002/cbic.201402673
Jähme, M., Guskov, A., & Slotboom, D. (2015). The twisted relation between Pnu and SWEET transporters. Trends in Biochemical Sciences, 40(4), 183-188. https://doi.org/10.1016/j.tibs.2015.02.002

2014

Meng, X., Dobruchowska, J. M., Pijning, T., Lopez-Bautista, C., Kamerling, J. P., & Dijkhuizen, L. (2014). Residue Leu(940) Has a Crucial Role in the Linkage and Reaction Specificity of the Glucansucrase GTF180 of the Probiotic Bacterium Lactobacillus reuteri 180. The Journal of Biological Chemistry, 289(47), 32773-32782. https://doi.org/10.1074/jbc.M114.602524
Pijning, T., Vujicic - Zagar, A., Kralj, S., Dijkhuizen, L., & Dijkstra, B. W. (2014). Flexibility of truncated and full-length glucansucrase GTF180 enzymes from Lactobacillus reuteri 180. Febs Journal, 281(9), 2159-2171. https://doi.org/10.1111/febs.12769
Balci, H., Ozturk, M. T., Pijning, T., Ozturk, S. I., & Gumusel, F. (2014). Improved activity and pH stability of E-coli ATCC 11105 penicillin acylase by error-prone PCR. Applied Microbiology and Biotechnology, 98(10), 4467-4477. https://doi.org/10.1007/s00253-013-5476-7
Pijning, T. (2014). Just add sugar... Structural Studies on Glucansucrase and Fructansucrase Enzymes from Lactobacilli. Groningen: s.n.
Jähme, M., Guskov, A., & Slotboom, D. J. (2014). Crystal structure of the vitamin B3 transporter PnuC, a full-length SWEET homolog. Nature Structural & Molecular Biology, 21(11), 1013-1015. https://doi.org/10.1038/nsmb.2909
ter Beek, J., Guskov, A., & Slotboom, D. J. (2014). Structural diversity of ABC transporters. Journal of general physiology, 143(4), 419-435. https://doi.org/10.1085/jgp.201411164

2013

Akbulut, N., Ozturk, M. T., Pijning, T., Ozturk, S. I., & Gumusel, F. (2013). Improved activity and thermostability of Bacillus pumilus lipase by directed evolution. Journal of Biotechnology, 164(1), 123-129. https://doi.org/10.1016/j.jbiotec.2012.12.016
Leemhuis, H., Pijning, T., Dobruchowska, J. M., van Leeuwen, S. S., Kralj, S., Dijkstra, B. W., & Dijkhuizen, L. (2013). Glucansucrases: Three-dimensional structures, reactions, mechanism, alpha-glucan analysis and their implications in biotechnology and food applications. Journal of Biotechnology, 163(2), 250-272. https://doi.org/10.1016/j.jbiotec.2012.06.037
Leemhuis, H., Dijkman, W. P., Dobruchowska, J. M., Pijning, T., Grijpstra, P., Kralj, S., ... Gerwig, G. J. (2013). 4,6-alpha-Glucanotransferase activity occurs more widespread in Lactobacillus strains and constitutes a separate GH70 subfamily. Applied Microbiology and Biotechnology, 97(1), 181-193. https://doi.org/10.1007/s00253-012-3943-1
Kemelbekov, U., Saipov, A., Abdildanova, A., Ospanov, I., Luo, Y., Guskov, A., ... Pichkhadze, G. (2013). Structure and pharmacological studies of the anaesthetic 1-(3-n-butoxypropyl)-4-benzoyloxypiperidin hydrochloride and its complex with beta-cyclodextrin in solution. NMR and IR-spectroscopy data. Journal of inclusion phenomena and macrocyclic chemistry, 77(1-4), 249-257. https://doi.org/10.1007/s10847-012-0239-0
Fulyani, F., Schuurman-Wolters, G. K., Vujicic - Zagar, A., Guskov, A., Slotboom, D-J., & Poolman, B. (2013). Functional Diversity of Tandem Substrate-Binding Domains in ABC Transporters from Pathogenic Bacteria. Structure, 21(10), 1879-1888. https://doi.org/10.1016/j.str.2013.07.020
Jensen, S., Guskov, A., Rempel, S., Hänelt, I., & Slotboom, D. J. (2013). Crystal structure of a substrate-free aspartate transporter. Nature Structural & Molecular Biology, 20(10), 1224-1226. https://doi.org/10.1038/nsmb.2663
Nordin, N., Guskov, A., Phua, T., Sahaf, N., Xia, Y., Lu, S., ... Eshaghi, S. (2013). Exploring the structure and function of Thermotoga maritima CorA reveals the mechanism of gating and ion selectivity in Co2+/Mg2+ transport. Biochemical Journal, 451(3), 365-374. https://doi.org/10.1042/BJ20121745
How, J., Zhang, A., Phillips, M., Reynaud, A., Lu, S. Y., Pan, L. X., ... Eshaghi, S. (2013). Comprehensive analysis and identification of the human STIM1 domains for structural and functional studies. PLoS ONE, 8(1), [e53979]. https://doi.org/10.1371/journal.pone.0053979
Kesters, D., Thompson, A. J., Brams, M., van Elk, R., Spurny, R., Geitmann, M., ... Ulens, C. (2013). Structural basis of ligand recognition in 5-HT3 receptors. Embo Reports, 14(1), 49-56. https://doi.org/10.1038/embor.2012.189

2012

Pijning, T., Vujicic-Zagar, A., Kralj, S., Dijkhuizen, L., & Dijkstra, B. W. (2012). Structure of the alpha-1,6/alpha-1,4-specific glucansucrase GTFA from Lactobacillus reuteri 121. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 68(12), 1448-1454. https://doi.org/10.1107/S1744309112044168
Anwar, M. A., Leemhuis, H., Pijning, T., Kralj, S., Dijkstra, B. W., & Dijkhuizen, L. (2012). The role of conserved inulosucrase residues in the reaction and product specificity of Lactobacillus reuteri inulosucrase. Febs Journal, 279(19), 3612-3621. https://doi.org/10.1111/j.1742-4658.2012.08721.x
Leemhuis, H., Pijning, T., Dobruchowska, J. M., Dijkstra, B. W., & Dijkhuizen, L. (2012). Glycosidic bond specificity of glucansucrases: on the role of acceptor substrate binding residues. Biocatalysis and Biotransformation, 30(3), 366-376. https://doi.org/10.3109/10242422.2012.676301
Augustyniak, W., Brzezinska, A. A., Pijning, T., Wienk, H., Boelens, R., Dijkstra, B. W., & Reetz, M. T. (2012). Biophysical characterization of mutants of Bacillus subtilis lipase evolved for thermostability: Factors contributing to increased activity retention. Protein Science, 21(4), 487-497. https://doi.org/10.1002/pro.2031
Brison, Y., Pijning, T., Malbert, Y., Fabre, E., Mourey, L., Morel, S., ... Dijkstra, B. W. (2012). Functional and Structural Characterization of alpha-(1 -> 2) Branching Sucrase Derived from DSR-E Glucansucrase. The Journal of Biological Chemistry, 287(11), 7915-7924. https://doi.org/10.1074/jbc.M111.305078
Guskov, A., Nordin, N., Reynaud, A., Engman, H., Lundbäck, A-K., Jong, A. J. O., ... Eshaghi, S. (2012). Structural insights into the mechanisms of Mg2+ uptake, transport, and gating by CorA. Proceedings of the National Academy of Sciences of the United States of America, 109(45), 18459-18464. https://doi.org/10.1073/pnas.1210076109
Guskov, A., & Eshaghi, S. (2012). The mechanisms of Mg2+ and Co2+ transport by the CorA family of divalent cation transporters. Current topics in membranes, 69, 393-414. https://doi.org/10.1016/B978-0-12-394390-3.00014-8

2011

Pijning, T., Anwar, M. A., Boger, M., Dobruchowska, J. M., Leemhuis, H., Kralj, S., ... Dijkstra, B. W. (2011). Crystal Structure of Inulosucrase from Lactobacillus: Insights into the Substrate Specificity and Product Specificity of GH68 Fructansucrases. Journal of Molecular Biology, 412(1), 80-93. https://doi.org/10.1016/j.jmb.2011.07.031
Palomo, M., Pijning, T., Booiman, T., Dobruchowska, J. M., Vlist, J. V. D., Kralj, S., ... Leemhuis, H. (2011). Thermus thermophilus Glycoside Hydrolase Family 57 Branching Enzyme: Crystal Structure, Mechanism of Action, and Products Formed. The Journal of Biological Chemistry, 286(5), 3520-3530. https://doi.org/10.1074/jbc.M110.179515
Broser, M., Glöckner, C., Gabdulkhakov, A., Guskov, A., Buchta, J., Kern, J., ... Zouni, A. (2011). Structural basis of cyanobacterial photosystem II Inhibition by the herbicide terbutryn. The Journal of Biological Chemistry, 286(18), 15964-15972. https://doi.org/10.1074/jbc.M110.215970
Kern, J., & Guskov, A. (2011). Lipids in photosystem II: Multifunctional cofactors. Journal of Photochemistry and Photobiology B: Biology, 104(1-2), 19-34. https://doi.org/10.1016/j.jphotobiol.2011.02.025
Brams, M., Gay, E. A., Sáez, J. C., Guskov, A., van Elk, R., van der Schors, R. C., ... Ulens, C. (2011). Crystal structures of a cysteine-modified mutant in loop D of acetylcholine-binding protein. The Journal of Biological Chemistry, 286(6), 4420-4428. https://doi.org/10.1074/jbc.M110.188730

2010

Vujičić-Žagar, A., Pijning, T., Kralj, S., López, C. A., Eeuwema, W., Dijkhuizen, L., & Dijkstra, B. W. (2010). Crystal structure of a 117 kDa glucansucrase fragment provides insight into evolution and product specificity of GH70 enzymes. Proceedings of the National Academy of Sciences of the United States of America, 107(50), 21406-21411. https://doi.org/10.1073/pnas.1007531107
Kale, A., Pijning, T., Sonke, T., Dijkstra, B. W., & Thunnissen, A-M. W. H. (2010). Crystal Structure of the Leucine Aminopeptidase from Pseudomonas putida Reveals the Molecular Basis for its Enantioselectivity and Broad Substrate Specificity. Journal of Molecular Biology, 398(5), 703-714. https://doi.org/10.1016/j.jmb.2010.03.042
Kemelbekov, U. S., Hagenbach, A., Lentz, D., Imachova, S. O., Pichkhadze, G. M., Rustembekov, Z. I., ... Saenger, W. (2010). Pharmacology and structures of the free base of the anaesthetic kazcaine and its complex with beta-cyclodextrin. Journal of inclusion phenomena and macrocyclic chemistry, 68(3-4), 323-330. https://doi.org/10.1007/s10847-010-9791-7
Broser, M., Gabdulkhakov, A., Kern, J., Guskov, A., Müh, F., Saenger, W., & Zouni, A. (2010). Crystal structure of monomeric photosystem II from Thermosynechococcus elongatus at 3.6-a resolution. The Journal of Biological Chemistry, 285(34), 26255-26262. https://doi.org/10.1074/jbc.M110.127589
Guskov, A., Gabdulkhakov, A., Broser, M., Glöckner, C., Hellmich, J., Kern, J., ... Zouni, A. (2010). Recent progress in the crystallographic studies of photosystem II. Chemphyschem : a European journal of chemical physics and physical chemistry, 11(6), 1160-1171. https://doi.org/10.1002/cphc.200900901

2009

Pijning, T., van Pouderoyen, G., Kluskens, L., van der Oost, J., & Dijkstra, B. W. (2009). The crystal structure of a hyperthermoactive exopolygalacturonase from Thermotoga maritima reveals a unique tetramer. FEBS Letters, 583(22), 3665-3670. https://doi.org/10.1016/j.febslet.2009.10.047
Gabdulkhakov, A., Guskov, A., Broser, M., Kern, J., Müh, F., Saenger, W., & Zouni, A. (2009). Probing the accessibility of the Mn(4)Ca cluster in photosystem II: Channels calculation, noble gas derivatization, and cocrystallization with DMSO. Structure, 17(9), 1223-34. https://doi.org/10.1016/j.str.2009.07.010
Guskov, A., Kern, J., Gabdulkhakov, A., Broser, M., Zouni, A., & Saenger, W. (2009). Cyanobacterial photosystem II at 2.9-A resolution and the role of quinones, lipids, channels and chloride. Nature Structural & Molecular Biology, 16(3), 334-342. https://doi.org/10.1038/nsmb.1559
Kern, J., Zouni, A., Guskov, A., & Krauss, N. (2009). Lipids in the Structure of Photosystem I, Photosystem II and the Cytochrome b6f Complex. In H. Wada, & N. Murata (Eds.), Lipids in Photosynthesis: Essential and Regulatory Functions (pp. 203-241). (Advances in Photosynthesis and Respiration; Vol. 30). Dordrecht, The Netherlands: Springer.

2008

Boersma, Y. L., Pijning, T., Bosma, M., van der Sloot, A. M., da Silva Godinho, L., Dröge, M., ... Quax, W. (2008). Loop grafting of Bacillus subtilis lipase A: Inversion of enantioselectivity. Chemistry & Biology, 15(8), 782-789. https://doi.org/10.1016/j.chembiol.2008.06.009
Boersma, Y. L., Droge, M. J., van der Sloot, A. M., Pijning, T., Cool, R. H., Dijkstra, B. W., ... Dröge, M. J. (2008). A novel genetic selection system for improved enantioselectivity of Bacillus subtilis lipase A. ChemBioChem, 9(7), 1110-1115. https://doi.org/10.1002/cbic.200700754
Pijning, T., Vujicic-Zagar, A., Kralj, S., Eeuwema, W., Dijkhuizen, L., & Dijkstra, B. W. (2008). Biochemical and crystallographic characterization of a glucansucrase from Lactobacillus reuteri 180. Biocatalysis and Biotransformation, 26(1-2), 12-17. https://doi.org/10.1080/10242420701789163

2005

Alagaratnam, S., van Pouderoyen, G., Pijning, T., Dijkstra, B. W., Cavazzini, D., Rossi, G. L., ... Van Berkel, WJH. (2005). A crystallographic study of Cys69Ala flavodoxin II from Azotobacter vinelandii: Structural determinants of redox potential: Structural determinants of redox potential. Protein Science, 14(9), 2284 - 2295. https://doi.org/10.1110/ps.051582605

2003

Fusetti, F., Pijning, T., Kalk, KH., Bos, E., Dijkstra, BW., & Dijkstra, B. W. (2003). Crystal structure and carbohydrate-binding properties of the human cartilage glycoprotein-39. The Journal of Biological Chemistry, 278(39), 37753-37760. https://doi.org/10.1074/jbc.M303137200

2002

Fusetti, F., Schröter, K. H., Steiner, R. A., Noort, P. I. V., Pijning, T., Rozeboom, H. J., ... Dijkstra, B. W. (2002). Crystal structure of the copper-containing quercetin 2,3-dioxygenase from Aspergillus japonicus. Structure, 10(2), 259-268. https://doi.org/10.1016/S0969-2126(02)00704-9

1998

Bordo, D., Monfort, R. L. M. V., Pijning, T., Kalk, K. H., Reizer, J., Saier Jr., M. H., & Dijkstra, B. W. (1998). The three-dimensional structure of the nitrogen regulatory protein IIA(Ntr) from Escherichia coli. Journal of Molecular Biology, 279(1), 245-255. https://doi.org/10.1006/jmbi.1998.1753
van Montfort, R., Pijning, T., Kalk, K. H., Hangyi, I., Kouwijzer, M., Robillard, G. T., & Dijkstra, B. W. (1998). The structure of the Escherichia coli phosphotransferase IIAmannitol reveals a novel fold with two conformations of the active site. Structure, 6(3), 377 - 388. https://doi.org/10.1016/S0969-2126(98)00039-2

1997

van Montfort, R. L. M., Pijning, T., Kalk, K. H., Reizer, J., Saier Jr., M. H., Thunnissen, M. M. G. M., ... Dijkstra, B. W. (1997). The structure of an energy-coupling protein from bacteria, IIBcellobiose, reveals similarity to eukaryotic protein tyrosine phosphatases. Structure, 5(2), 217-225. https://doi.org/10.1016/S0969-2126(97)00180-9

1994

Nijssen, HMJ., Pijning, T., Proost, JH., Meijer, DKF., & Groothuis, GMM. (1994). The sinusoidal efflux of dibromosulfophthalein from rat liver is stimulated by albumin, ligandin and fatty acid binding protein but not by other dibromosulfophthalein binding proteins. Journal of Hepatology, 21(1), 29-36. https://doi.org/10.1016/S0168-8278(94)80133-9
van Montfort, R., Pijning, T., Kalk, K., Schuurman-Wolters, G. K., Reizer, J., Safer Jr., M. H., ... Dijkstra, B. W. (1994). Crystallization of Enzyme IIB of the Cellobiose-specific Phosphotransferase System of Escherichia coli. Journal of Molecular Biology, 239(4), 588-590. https://doi.org/10.1006/jmbi.1994.1399

1992

VERLINDE, CLMJ., WITMANS, CJ., PIJNING, T., KALK, KH., HOL, WGJ., CALLENS, M., & OPPERDOES, FR. (1992). STRUCTURE OF THE COMPLEX BETWEEN TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE AND N-HYDROXY-4-PHOSPHONO-BUTANAMIDE - BINDING AT THE ACTIVE-SITE DESPITE AN OPEN FLEXIBLE LOOP CONFORMATION. Protein Science, 1(12), 1578-1584.
NIJSSEN, HMJ., PIJNING, T., MEIJER, DKF., & GROOTHUIS, GMM. (1992). INFLUENCE OF ALBUMIN ON THE NET SINUSOIDAL EFFLUX OF THE ORGANIC ANION DIBROMOSULFOPHTHALEIN FROM RAT-LIVER. Hepatology, 15(2), 302-309.

1991

NIJSSEN, HMJ., PIJNING, T., MEIJER, DKF., & GROOTHUIS, GMM. (1991). MECHANISTIC ASPECTS OF UPTAKE AND SINUSOIDAL EFFLUX OF DIBROMOSULFOPHTHALEIN IN THE ISOLATED PERFUSED-RAT-LIVER. Biochemical Pharmacology, 42(10), 1997-2002.

1989

BRAAKMAN, N. V., PIJNING, T., VEREST, O., WEERT, B., MEIJER, DKF., & GROOTHUIS, GMM. (1989). VESICULAR UPTAKE SYSTEM FOR THE CATION LUCIGENIN IN THE RAT HEPATOCYTE. Molecular Pharmacology, 36(4), 537-542.
BRAAKMAN, N. V., VEREST, O., PIJNING, T., MEIJER, DKF., & GROOTHUIS, GMM. (1989). ZONAL DISTRIBUTION OF THE CATION LUCIGENIN IN RAT-LIVER - INFLUENCE OF TAUROCHOLATE. Molecular Pharmacology, 36(4), 532-536.
Last modified:19 September 2017 10.48 a.m.