Skip to ContentSkip to Navigation
About usNews and EventsNews articles

Immune regulation by allergen immunotherapy. Lessons learned from experimental approaches

11 April 2012

PhD ceremonies: Ms. S. Shirinbak, 14.30 uur and Mr. H. Maazi, 16.15 uur, Academiegebouw, Broerstraat 5, Groningen

Dissertation: Immune regulation by allergen immunotherapy. Lessons learned from experimental approaches

Promotor(s): prof. A.J.M. van Oosterhout

Faculty: Medical Sciences

In this PhD thesis we aimed to unravel the mechanism of action of SIT at cellular level on the one hand and find ways to improve the efficacy of SIT in the other hand in a mouse model of allergic asthma. We found that while FOXP3+ regulatory T cells play a role in SIT-induced suppression of airway eosinophilia, CD8+ T cells, B cells and plasmacytoid dendritic cells play dispensable roles in SIT-induced suppression of airway hyperreactivity, airway eosinophilia and allergen-specific IgE levels in the serum.

Last modified:15 September 2017 3.42 p.m.
printView this page in: Nederlands

More news

  • 15 May 2019

    Academy Medal for Trudy Dehue

    Trudy Dehue, scientific sociologist, author and emeritus professor of the University of Groningen, will receive the Academy Medal from the Royal Netherlands Academy of Arts and Sciences (KNAW). The Academy Medal is awarded every other year to individuals...

  • 15 May 2019

    Van Rijn advice hits UG hard

    The advice from the Van Rijn committee concerning the funding of higher education has heavy consequences for the UG as a broad-based classical university. The proposed redistribution of funds in favour of technical sciences is at the expense of degree...

  • 14 May 2019

    Number of children with type 1 diabetes doubled

    The number of children who are annually diagnosed with type 1 diabetes has doubled over the last 30 years. This is one of the conclusions of the PhD thesis written by Angelien Spaans-Hummelink, who works as a paediatrician at the diabetes clinic at...