Skip to ContentSkip to Navigation
About us Latest news Events PhD ceremonies

Chemical approaches for quantitative proteomics

PhD ceremony:Mr X. (Xiaobo) Tian
When:September 24, 2021
Supervisor:prof. dr. R.P.H. (Rainer) Bischoff
Co-supervisor:dr. H.P. (Hjalmar) Permentier
Where:Academy building RUG
Chemical approaches for quantitative proteomics

Xiaobo focuses on developing novel isotope labeling-based tags for quantitative proteomics along two lines of research: (1) In data-dependent acquisition (DDA) mode, eliminating the ratio distortion caused by peptide cofragmentation and increasing the multiplexing capacity. (2) In data-independent acquisition (DIA) mode, achieving multiplexed quantification with general DIA LC-MS settings. The representative work, Ac-IP tag that specifically suitable for the multiplexing in DIA mode, attracted much attention from peers.