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About usHow to find usprof. dr. R. (Reinoud) Gosens

prof. dr. R. Gosens

Associate Professor
prof. dr. R. Gosens
E-mail:
r.gosens rug.nl

PERSONAL INFORMATION

Name:                                                 Reinoud Gosens

Date of birth:                                      September 10, 1977

Nationality:                                         Dutch

URL Website (staff profile):               http://www.rug.nl/staff/r.gosens/

Google Scholar profile: https://scholar.google.nl/citations?user=b-Bv39MAAAAJ&hl=en

 

EDUCATION

2004                PhD in Pharmacology (cum laude). PhD supervisor: Prof. dr. Johan Zaagsma.

                        Faculty of Mathematics and Natural Sciences, University of Groningen, the Netherlands.

2000                Master in Pharmacy (cum laude). MSc supervisor: Prof. dr. Johan Zaagsma.

                        Faculty of Mathematics and Natural Sciences, University of Groningen, the Netherlands.

 

CURRENT POSITION

2015 –  current           Associate Professor of Translational Pharmacology (tenured).

                        Groningen Institute of Pharmacy, University of Groningen, the Netherlands

 

PREVIOUS POSITIONS

2009 – 2014    Assistant Professor of Translational Pharmacology.

                        Groningen Research Institute for Pharmacy, University of Groningen, the Netherlands

2007 – 2009    Post-doctoral research fellow.

                        Groningen Research Institute for Pharmacy, University of Groningen, the Netherlands.

2004 – 2007    Post-doctoral research fellow.

                        Faculty of Medicine, Department of Physiology, University of Manitoba, Canada.

 

FELLOWSHIPS GRANTS AND AWARDS (past 5 years)

2017                Project Grant, ZonMW. (250 k€).

                                   ‘NEURO-Chip: neural control of internal organ pathophysiology’

2017                Consortium Grant, Netherlands Lung Foundation. (666 k€).

‘Targeting the COPD lung microenvironment for lung repair: mechanisms and novel therapeutic opportunities’

2014                Consortium Grant, Netherlands Lung Foundation. (550 k€).

‘Tissue repair in COPD: WNT you get it right?’

2014                Project Grant, Boehringer Ingelheim. (220 k€).

                                   ‘The protective effects of tiotropium: role of the muscarinic M3 receptor’

2013                Project Grant, Chiesi Farmaceutici. (80 k€).

                        ‘evaluation of CHF-5843, a novel long-acting anticholinergic, alone and in concerted action with CHF-6001, a PDE inhibitor, in a guinea pig model of COPD.’

2012                            NWO Vidi Grant, Netherlands Organization for Scientific Research, (800 k€).

                        ‘On the developmental origins of airway smooth muscle thickening in asthma’

 

SUPERVISION OF GRADUATE STUDENTS AND POSTDOCTORAL FELLOWS

Post-doctoral research fellows (4): Tjitske Oenema (2013-2014), Cécile Bidan (2014), Loes Kistemaker (2014-2016), John-Poul Ng-Blichfeldt (2015-2018)

PhD students (14): Tonio Pera (2006-2011), Hoeke Baarsma (2008-2013), Tjitske Oenema (2008-2013), Loes Kistemaker (2010-2014), Kuldeep Kumawat (2010-2014), Anita Spanjer (2011-2015), Sepp Jansen (2011-2015), Tim Koopmans (2012-2016), Eline van Dijk (2012-2016), Navessa Padma Tania (2013-2017), Mariska van den Berg (2016-2020), Xinhui Wu (2016-2020), Marina Mastelaro de Rezende (2016-2019), Pien Goldsteen (2017-2021), Siti Farah Rahmawati (2018-2022), Chiara Ciminieri (2018-2022).

TEACHING ACTIVITIES  

2009 – current            Teaching in Pharmacology, Schools of Pharmacy and Medical Pharmaceutical Sciences, University of Groningen, the Netherlands.

Topics: Receptor Pharmacology, Practical Pharmacology, Tutor.

INSTITUTIONAL RESPONSIBILITIES (University of Groningen)

2017 –             Board Member, Groningen Research Institute for Pharmacy (GRIP).         

2015 –             Co-chair, Groningen Research Institute for Asthma and COPD (GRIAC).

2013 –             Board Member, Groningen Research Institute for Asthma and COPD (GRIAC).

2009 –             Member, Pharmacy curriculum evaluation committee.

EDITORIAL BOARDS

Editor for the British Journal of Pharmacology (as of October 2016).

Associate Editor for Respiratory Research (until October 2016).

Associate Editor for Frontiers in Physiology – Respiratory section (2015 - present).

Editor for the European Journal of Pharmacology (2011 - present).

MEMBERSHIPS OF SCIENTIFIC SOCIETIES

2010 –             Member, Netherlands Respiratory Society.

2008 –             Member, European Respiratory Society.

2008 –             Member, American Physiological Society.

2004 –             Member, American Thoracic Society.

2004 –             Member, Dutch Pharmacological Society.

 

OTHER INTERNATIONAL ACADEMIC ACTIVITIES

> 70 invited lectures at conferences, symposia and universities.

> 40 visits to international conferences

14 participations as external referee for PhD committees

Reviewer for >100 articles and >40 grant proposals

 

SELECTED PUBLICATIONS

I have authored, or co-authored a total of 110 publications at the moment, of which 65 are multi-institutional. See https://scholar.google.nl/citations?user=b-Bv39MAAAAJ&hl=en for a full publication list. The following publications highlight the nature of my work:

 

Gosens R, Bos IST, Zaagsma J & Meurs H. (2005) Protective effects of tiotropium bromide in the progression of airway smooth muscle remodeling. Am J Respir Crit Care Med, 171:1096-1102.

Kumawat K, Menzen MH, Bos IST, Baarsma HA, Borger P, Roth M, Tamm M, Halayko AJ, Simoons M, Prins A, Postma DS, Schmidt M & Gosens R. (2013) Non-canonical WNT-5A signaling regulates TGF-β-induced extracellular matrix production by airway smooth muscle cells. FASEB J, 27:1631-1643.

Baarsma HA, Spanjer AIR, Haitsma G, Engelbertink LHJM, Meurs H, Jonker MR, Timens W, Postma DS, Kerstjens HAM & Gosens R. (2011). Activation of WNT/β-catenin signaling in pulmonary fibroblasts by TGF-β1 is increased in chronic obstructive pulmonary disease. PLoS One, 6:e25450.

Spanjer AI, Baarsma HA, Oostenbrink LM, Jansen SR, Kuipers CC, Lindner M, Postma DS, Meurs H, Heijink IH, Königshoff M*, Gosens R*. (2016). TGF-β-induced profibrotic signaling is regulated in part by the WNT receptor Frizzled-8. FASEB J. 30:1823-1835. * Shared senior authorship.

Spanjer AI, Menzen MH, Dijkstra AE, van den Berge M, Boezen HM, Nickle DC, Sin DD, Bossé Y, Brandsma CA, Timens W, Postma DS, Meurs H, Heijink IH, Gosens R. (2016). A pro-inflammatory role for the Frizzled-8 receptor in chronic bronchitis. Thorax. 71:312-322.

 

Last modified:01 March 2018 1.20 p.m.

Contact information

Department of Molecular Pharmacology

Job title:
Associate Professor
Room:
3214.409