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Practical matters How to find us M. (Marij) Zuidersma
University Medical Center Groningen

M. (Marij) Zuidersma

Post doc researcher
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BEAT-IT: Boosting antidepressant treatment by personalized ESM-based feedback – A feasibility study in older people.

Role: part of team

Period: 2022-2023

Funding: ZonMW

i-CASE: idiographic study on Cognitive function, Affect and Sleep in the Elderly (onderzoek naar stemming, slaap en denkvermogen in het dagelijks leven)

Role: Principal investigator

Period: 2014-2019

Funding: Stichting MIND and Alzheimer Nederland

Published papers:

Zuidersma, M., Lugtenburg, A., Van Zelst, W., Reesink, F., De Deyn, P., Strijkert, F., . . . Oude Voshaar, R. (2022). Temporal dynamics of depression, cognitive performance and sleep in older persons with depressive symptoms and cognitive impairments: A series of eight single-subject studies.  International Psychogeriatrics, 34(1), 47-59. doi:10.1017/S1041610221000065

Zdanowski, S., Tieks, A., Jeronimus, B.F., Zuidersma, M. ‘Intra-Individual Variability in Cognitive Performance Can Befuddle the Study of Cognitive Impairments and Decline’. 1 Jan. 2022 : 519 – 525.

Tieks A, Oude Voshaar RC, Zuidersma M. Daily associations between affect and cognitive performance in older adults with depression and cognitive impairment: a series of seven single-subject studies in the Netherlands. BMC Geriatr. 2022 Feb 17;22(1):133. doi: 10.1186/s12877-022-02797-y. PMID: 35177005; PMCID: PMC8851709.

Zuidersma M, Müller F, Snippe E, Zuidema SU, Oude Voshaar RC. Feasibility, usability and clinical value of intensive longitudinal diary assessments in older persons with cognitive impairment and depressive symptoms. Aging Ment Health. 2022 Jul 23:1-10. doi: 10.1080/13607863.2022.2102143. Epub ahead of print. PMID: 35876158.

Sleep and Agitation in patients with dementia in nursing homes (slaap en agitatie bij mensen met dementie in het verpleeghuis)

Role: Co-investigator

Period: 2016-2018

Funder: Verenso

Published paper: 

Wijbenga RA, Blaauw FJ, Janus SIM, Tibben C, Smits AE, Oude Voshaar RC, Zuidema SU, Zuidersma M. Individual differences in the temporal relationship between sleep and agitation: a single-subject study in nursing home residents with dementia experiencing sleep disturbance and agitation. Aging Ment Health. 2022 Aug;26(8):1669-1677. doi: 10.1080/13607863.2021.1935464. Epub 2021 Jun 15. PMID: 34129803.

NESDO (Netherlands Study of Depression in Older persons)

Role: Part of team

Period: ongoing

Published papers:

Lugtenburg A, Zuidersma M, Wardenaar KJ, Aprahamian I, Rhebergen D, Schoevers RA, Oude Voshaar RC. Subtypes of Late-Life Depression: A Data-Driven Approach on Cognitive Domains and Physical Frailty. J Gerontol A Biol Sci Med Sci. 2021 Jan 1;76(1):141-150. doi: 10.1093/gerona/glaa110. PMID: 32442243.

Kuiper JS, Smidt N, Zuidema SU, Comijs HC, Oude Voshaar RC, Zuidersma M. A longitudinal study of the impact of social network size and loneliness on cognitive performance in depressed older adults. Aging Ment Health. 2020 Jun;24(6):889-897. doi: 10.1080/13607863.2019.1571012. Epub 2019 Feb 7. PMID: 30729792.

Bogers ICHM, Zuidersma M, Boshuisen ML, Comijs HC, Oude Voshaar RC. The influence of thoughts of death and suicidal ideation on the course of depression in older depressed patients. Int J Geriatr Psychiatry. 2017 Aug;32(8):882-891. doi: 10.1002/gps.4541. Epub 2016 Jul 5. PMID: 27384251.

Zuidersma M, Comijs HC, Naarding P, Oude Voshaar RC. Cognitive performance in depressed older persons: the impact of vascular burden and remission. A two-year follow-up study. Int J Geriatr Psychiatry. 2016 Sep;31(9):1029-39. doi: 10.1002/gps.4416. Epub 2016 Jan 25. PMID: 26807666.

Arts MH, Collard RM, Comijs HC, Zuidersma M, de Rooij SE, Naarding P, Oude Voshaar RC. Physical Frailty and Cognitive Functioning in Depressed Older Adults: Findings From the NESDO Study. J Am Med Dir Assoc. 2016 Jan;17(1):36-43. doi: 10.1016/j.jamda.2015.07.016. Epub 2015 Sep 1. PMID: 26341037.

Zuidersma M, Izaks GJ, Naarding P, Comijs HC, Oude Voshaar RC. Vascular burden and cognitive function in late-life depression. Am J Geriatr Psychiatry. 2015 May;23(5):514-24. doi: 10.1016/j.jagp.2014.06.010. Epub 2014 Jul 2. PMID: 25091518.

Naudé PJ, den Boer JA, Comijs HC, Bosker FJ, Zuidersma M, Groenewold NA, De Deyn PP, Luiten PG, Eisel UL, Oude Voshaar RC. Sex-specific associations between Neutrophil Gelatinase-Associated Lipocalin (NGAL) and cognitive domains in late-life depression. Psychoneuroendocrinology. 2014 Oct;48:169-77. doi: 10.1016/j.psyneuen.2014.06.016. Epub 2014 Jun 27. PMID: 25019974.

Bogers IC, Zuidersma M, Boshuisen ML, Comijs HC, Oude Voshaar RC. Determinants of thoughts of death or suicide in depressed older persons. Int Psychogeriatr. 2013 Nov;25(11):1775-82. doi: 10.1017/S1041610213001166. Epub 2013 Aug 9. PMID: 23927927.


Astrid Lugtenburg: depression, physical functioning, cognitive decline and dementia.

Alieke Tieks: Does one size fits all? Addressing heterogeneity in the association of depression and cognitive performance.


Staff-member of the iLab (

Last modified:06 August 2022 11.51 a.m.