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About us Practical matters How to find us M.R. (Matthew) Groves, Prof

Research interests

Applied Research Activities

Structure-based drug design in human diseases

Basic Research Activities

Structural, biochemical and molecular biology investigation of malarial pathways:

Carbon metabolism in P falciparum

Vitamin biosynthesis in P. falciparum

Method Developments

Crystal identification for structural biology

Biological imaging on free-electron lasers 


Engineering a Plant Polyketide Synthase for the Biosynthesis of Methylated Flavonoids

Small-Molecule Allosteric Inhibitors of Human Aspartate Transcarbamoylase Suppress Proliferation of Bone Osteosarcoma Epithelial Cells

A comprehensive overview of the heterogeneity of EGFR exon 20 variants in NSCLC and (pre)clinical activity to currently available treatments

Correction: Isolation and molecular characterization of novel glucarpidases: Enzymes to improve the antibody directed enzyme pro-drug therapy for cancer treatment

Determination of Binding Sites on Trastuzumab and Pertuzumab to Selective Affimers Using Hydrogen-Deuterium Exchange Mass Spectrometry

Fragment Screening in the Development of a Novel Anti-Malarial

Identification and Characterization of a Small Molecule that Activates Thiosulfate Sulfurtransferase and Stimulates Mitochondrial Respiration

Inhibitors of Aspartate Transcarbamoylase Inhibit Mycobacterium tuberculosis Growth

Novel inhibitors of aspartate transcarbamoylase (atcase) and compositions, methods and uses related thereto

Structural characterization and extended substrate scope analysis of two Mg<sup>2+</sup>-dependent O-methyltransferases from bacteria

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