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Practical matters How to find us M.R. (Matthew) Groves, Prof Dr

Research interests

Applied Research Activities

Structure-based drug design in human diseases

Basic Research Activities

Structural, biochemical and molecular biology investigation of malarial pathways:

Carbon metabolism in P falciparum

Vitamin biosynthesis in P. falciparum

Method Developments

Crystal identification for structural biology

Biological imaging on free-electron lasers 


Structural characterization and extended substrate scope analysis of two Mg<sup>2+</sup>-dependent O-methyltransferases from bacteria

Actionability of on-target ALK Resistance Mutations in Patients With Non-Small Cell Lung Cancer: Local Experience and Review of the Literature

Design, synthesis and biological evaluation of 1,5-disubstituted α-amino tetrazole derivatives as non-covalent inflammasome-caspase-1 complex inhibitors with potential application against immune and inflammatory disorders

Discovery of Small-Molecule Allosteric Inhibitors of PfATC as Antimalarials

Engineering a plant polyketide synthase for the biosynthesis of methylated flavonoids

Feasibility of Follow-Up Studies and Reclassification in Spinocerebellar Ataxia Gene Variants of Unknown Significance

First crystal structures of 1-deoxy-D-xylulose 5-phosphate synthase (DXPS) from Mycobacterium tuberculosis indicate a distinct mechanism of intermediate stabilization

Multicomponent Macrocyclic IL-17a Modifier

Novel Highlight in Malarial Drug Discovery: Aspartate Transcarbamoylase

Synthetic peptides blocking sars-cov-2 (covid-19), and compositions, methods and uses related thereto

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