prof. dr. M.R. (Matthew) Groves

Associate Professor

prof. dr. M.R. (Matthew) Groves


Postal address:
A Deusinglaan1
Gebouw 3211, ruimte 0474
9713 AV
Phone: +31 50 363 3305Fax: +31 50 363 6908

Research interests

Applied Research Activities

Structure-based drug design in human diseases

Basic Research Activities

Structural, biochemical and molecular biology investigation of malarial pathways:

Carbon metabolism in P falciparum

Vitamin biosynthesis in P. falciparum

Method Developments

Crystal identification for structural biology

Biological imaging on free-electron lasers 

  1. Unraveling the role of thiosulfate sulfurtransferase in metabolic diseases

    Kruithof, P. D., Lunev, S., Aguilar Lozano, S. P., de Assis Batista, F., Al-Dahmani, Z. M., Joles, J. A., Dolga, A. M., Groves, M. R. & van Goor, H., 12-Feb-2020, In : Biochimica et biophysica acta-Molecular basis of disease. 1866, 6, 165716.

    Research output: Contribution to journalReview articleAcademicpeer-review

  2. Theory and applications of differential scanning fluorimetry in early-stage drug discovery

    Gao, K., Oerlemans, R. & Groves, M. R., 31-Jan-2020, In : Biophysical reviews. 12, p. 85-104

    Research output: Contribution to journalReview articleAcademicpeer-review

  3. Multicomponent Peptide Stapling as a Diversity-Driven Tool for the Development of Inhibitors of Protein-Protein Interactions

    Ricardo, M., Ali, A., Plewka, J., Surmiak, E., Labuzek, B., Neochoritis, C., Atmaj, J., Skalniak, L., Zhang, R., Holak, T., Groves, M., Rivera, D. & Doemling, A., 15-Jan-2020, In : Angewandte Chemie (International ed. in English).

    Research output: Contribution to journalArticleAcademicpeer-review

  4. New directions in antimalarial target validation

    Batista, F. A., Gyau, B., Vilacha, J. F., Bosch, S. S., Lunev, S., Wrenger, C. & Groves, M. R., 1-Feb-2020, In : Expert Opinion on Drug Discovery. 15, 2, p. 189-202 14 p.

    Research output: Contribution to journalReview articleAcademicpeer-review

  5. Osimertinib treatment for patients with EGFR exon 20 mutation positive non-small cell lung cancer

    van Veggel, B., Madeira R Santos, J. F. V., Hashemi, S. M. S., Paats, M. S., Monkhorst, K., Heideman, D. A. M., Groves, M., Radonic, T., Smit, E. F., Schuuring, E., van der Wekken, A. J. & de Langen, A. J., 20-Dec-2019, In : Lung Cancer. 141, p. 9-13 5 p.

    Research output: Contribution to journalArticleAcademicpeer-review

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  1. Pharmacy Day 2018

    Anna Salvati (Organiser), Amalia Dolga (Organiser), Matthew Groves (Organiser), Klaus Mathwig (Organiser), Peter Horvatovich (Organiser), Wim J. Quax (Organiser), Anne Lexmond (Organiser), Gillian Dempsey (Organiser)

    Activity: Participating in or organising an eventOrganising an eventAcademic

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