prof. dr. M.R. (Matthew) Groves

Associate Professor

prof. dr. M.R. (Matthew) Groves
E-mail:
m.r.groves rug.nl

Research

Postal address:
A Deusinglaan1
Gebouw 3211, ruimte 0474
9713 AV
Groningen
Netherlands
Phone: +31 50 363 3305Fax: +31 50 363 6908

Research interests

Applied Research Activities

Structure-based drug design in human diseases

Basic Research Activities

Structural, biochemical and molecular biology investigation of malarial pathways:

Carbon metabolism in P falciparum

Vitamin biosynthesis in P. falciparum

Method Developments

Crystal identification for structural biology

Biological imaging on free-electron lasers 

Publications
  1. Unraveling the role of thiosulfate sulfurtransferase in metabolic diseases

    Kruithof, P. D., Lunev, S., Aguilar Lozano, S. P., de Assis Batista, F., Al-Dahmani, Z. M., Joles, J. A., Dolga, A. M., Groves, M. R. & van Goor, H., 12-Feb-2020, In : Biochimica et biophysica acta-Molecular basis of disease. 1866, 6, 165716.

    Research output: Contribution to journalReview articleAcademicpeer-review

  2. Theory and applications of differential scanning fluorimetry in early-stage drug discovery

    Gao, K., Oerlemans, R. & Groves, M. R., 31-Jan-2020, In : Biophysical reviews. 12, p. 85-104

    Research output: Contribution to journalReview articleAcademicpeer-review

  3. Multicomponent Peptide Stapling as a Diversity-Driven Tool for the Development of Inhibitors of Protein-Protein Interactions

    Ricardo, M., Ali, A., Plewka, J., Surmiak, E., Labuzek, B., Neochoritis, C., Atmaj, J., Skalniak, L., Zhang, R., Holak, T., Groves, M., Rivera, D. & Doemling, A., 15-Jan-2020, In : Angewandte Chemie (International ed. in English).

    Research output: Contribution to journalArticleAcademicpeer-review

  4. New directions in antimalarial target validation

    Batista, F. A., Gyau, B., Vilacha, J. F., Bosch, S. S., Lunev, S., Wrenger, C. & Groves, M. R., 1-Feb-2020, In : Expert Opinion on Drug Discovery. 15, 2, p. 189-202 14 p.

    Research output: Contribution to journalReview articleAcademicpeer-review

  5. Osimertinib treatment for patients with EGFR exon 20 mutation positive non-small cell lung cancer

    van Veggel, B., Madeira R Santos, J. F. V., Hashemi, S. M. S., Paats, M. S., Monkhorst, K., Heideman, D. A. M., Groves, M., Radonic, T., Smit, E. F., Schuuring, E., van der Wekken, A. J. & de Langen, A. J., 20-Dec-2019, In : Lung Cancer. 141, p. 9-13 5 p.

    Research output: Contribution to journalArticleAcademicpeer-review

View all (82) »

Activities
  1. Pharmacy Day 2018

    Anna Salvati (Organiser), Amalia Dolga (Organiser), Matthew Groves (Organiser), Klaus Mathwig (Organiser), Peter Horvatovich (Organiser), Wim J. Quax (Organiser), Anne Lexmond (Organiser), Gillian Dempsey (Organiser)
    12-Jun-2018

    Activity: Participating in or organising an eventOrganising an eventAcademic

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