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How to find us prof. dr. M.A.J. (Marina) de Koning-Tijssen
University Medical Center Groningen

prof. dr. M.A.J. de Koning-Tijssen

Hoogleraar Bewegingsstoornissen, neuroloog
prof. dr. M.A.J. de Koning-Tijssen

Prof dr Marina AJ de Koning-Tijssen (1964) started her medical studies in 1982 and finished  (cum laude) in 1990 at the Leiden University. For her doctoral thesis she worked for five months as a research fellow with Prof DS Zee, Department of Neurology, Johns Hopkins University, Baltimore, USA.

In the period 1991 -1998 she was a resident at the department of neurology, Leiden University Medical Centre (Prof Dr RAC Roos). She defended her thesis' Hyperekplexia, startle disease' in 1997 and finished her neurology training in 1999.

As a clinical and research fellow she worked 14 months (1998-1999) at the prestigious MRC Human Movement and Balance Unit, The Institute of Neurology, Queen Square, London, England with prof P Brown.

From September 1999 till January 2012 she worked as a neurologist and from 2007 as Principal Investigator in the department of neurology, Academic Medical Centre, Amsterdam. During this period she was co-promotor five times. Over the years she supervised several medical students, PhD students, research fellows, and neurologists performing a clinical fellowship. She regularly is member of PhD defending committees, gives lectures, teaching courses, and organises national and international congresses. 

In January, 2012 she started as professor in Movement Disorders at the department of neurology, University Medical Centre Groningen.

The most prestigious prizes awarded to her are the NWO-VIDI Laureaat (2004) for the project “Myoclonic Dystonia: borderland between neurology and psychiatry” and the ZonMW-TOP grant (2019) for the project " Next Generation Phenotyping: The next move in movement disorders".


Her research line Jerky movements (Myoclonus-Tics-Startle) & Dystonia is from basic research to patient care.

Clinical studies are focussed on the phenotyping the movement disorders and studying the psychiatric and cognitive co-morbidity. 

Basic research is focussed on genetic aspects. A large database on hyperkinetic movment disorders has been built and genetic studies are performed

Functional studies include neurophysiological and imaging studies (functional MRI and SPECT/PET). The aim of the functional studies is to improve diagnostic procedures and to gain inside in the pathophysiology of movement disorders.


In 2010 she initiated Dystonie Net, a national collaboration between neurologists and physical therapists on research, education and treatment of cervical dystonia in collaboration with the neurology departments of the UMCG, AMC, LUMC, and UMCN. At the UMCG she is one of the initiators of the multidisciplinary outpatient clinic pediatric movement disorders (2012).  In 2014 the neuropsychiatric movement disorder multidisciplinary outpatient clinic  started. She was involved in the DystonieNET national protocol botulinum toxin treatment cervical dystonia (2013).

She is head of the in 2015 officially established Expertisecenter for movement disorders in children and adults. The centre is officially part of the European Rare Network (ERN) for rare neurological disorders. The centre includes 10 disorders: dystonia, myoclonus, paroxysmal dyskinesia, hyperekplexia, psychogenic movement disorders, ataxia, inherited congenital spastic tetraplegia, rare choreic movement disorder & Huntington's disease, neurodegeneration with brain iron accumulation, and neurometabolic disease related to movement disorders.


2019       B Nijmeijer                           Torticollis: Identification of cortical and spinal motor contributions in cervical dystonia. University of Amsterdam

2018      M Kuiper                               The clinical assessment of motor behaviour in developing children. University of Groningen

2018       R Brandsma                          The reliability of diagnostic measures in Early Onset Ataxia. University of Groningen

2018       R Zutt                                     Myoclonus: a clinical approach. University of Groningen

2018      E Zoons                                 Dopamine-serotonin dysbalance and the relation to Myoclonus and psychiatric co-morbidity in dystonia. University of Amsterdam

2017       M Broersma                         Neuroimaging in tremor and functional motor disorders. University of Groningen

2017      C Mentzel                              'The course recognition and treatment of movement disorders in severe mental illness'. Psychiatry, University of Maastricht.

2017       M Smit                                   Psychiatric co-morbidity in dystonia syndromes: is serotonin the common pathway? University of Groningen

2017       S vd Salm                              Functional & psychiatric studies and jerky movements. University of Amsterdam

2017       E Nibbeling                          Genetics in dystonia and ataxia. Genetics, University of Groningen

2016      E Smit                                    Graphical tasks to aid in diagnosing and monitoring Parkinson's disease. University of Groningen

2015       M vd Stouwe                        Diagnosis and imaging of essential and other tremors. University of Groningen

2014       E de Bruijn                            Isometric and dynamic control of neck muscles. Reflexive contributions and muscle synergies. Delft University of Technology.

2014       J Groen                                   Genetic associations in focal dystonia. University of Amsterdam

2013       F Contarino                           Improving surgical treatment for Movement disorders. University of Amsterdam

2012       J vd Meer                               Functional changes in hyperkinetic movement disorders; an EMG-EEG-fMRI study. Physicist, University of Amsterdam

Co-promotor (University of Amsterdam)

2012       K Ritz                                    Genetic studies in Myoclonus Dystonia, geneticist

2011       R Beukers                             Imaging in hyperkinetic movement disorders

2009       M Bakker                              The Startle reflex in anxious children, psychologist

2008       EM Foncke                           Myoclonus Dystonia; clinical and functional aspects

2006       AF van Rootselaar               Familial cortical myoclonus or tremor with epilepsy

Awarded with the Storm van Leeuwen - Magnus price 2009.


2019       MDS International Executive Committee 2019-2023.

2019-     Transitional Board of Directors Functional Neurological Disorder Society. 

2017-     Secretary, Int. Parkinson & Movement Dis. Society-European Section

2017-     Task force Genetic Nomenclature, Int. Parkinson & Mov. Dis. Society

2016-     European Rare disorder Network board. Rare Neurological Disorders.

WP4 chair: Expert Care Coordination.

2016-     Rare Disorders committee, European Academy of Neurology

2016-     Task force Rare Movement Disorders, Int. Parkinson & Mov. Dis. Society

2015-17 Secretary-Elect, Int. Parkinson & Movement Dis. Society-European Section

2014-     Task force Dystonia, Int. Parkinson & Movement Disorders Society

2013-17 Program committee, Int. Parkinson & Movement Disorders Society

2011-16 Chair of clinical line, European COST platform Dystonia.

2011-16 Member board of Dystonia Europe

2009-17(chair 2013-) Bylaws committee Int. Parkinson & Mov. Dis. Society



2017-                     Behandeling/ diagnostiek CP/bewegingsstoornissen bij kinderen

2015-                     Chair of the national expertise center Movement Disorders Groningen, since 2016 oficially part of an European Reference Network: Rare Neurological Disorders (

2014-2017            Member NWO-GOVIDI advisory board

2010-                     President DystonieNet (

2009- 2012           Member NWO-VENI advisory board

2008- 2012           Member Scientific advisory board Prinses Beatrix Fonds

2008- 2012           Member WFN Research Group on Parkinsonism and Related Disorders

2006-                     Member (2006-11 President) Dutch movement disorder section

2005- 2009          Member of the board of the Dutch-Flemish Tourette Surgery Study Group

2004-2018            Member (2008-, President) medical advisory board dystonia patient society


Local Groningen

2013-2016            Healthy Aging / ‘Doelmatigheid’ Grant committee

2014-                      MD-PhD Grant committee

2014-                      VENI advisory board

Editorial board

2016-           Editorial Board ‘’Basal Ganglia’

2014-           Editorial Board Journal of Clinical Movement Disorders

2011-           Editor frontiers in movement disorders

Nevenwerkzaamheden: geen


Laatst gewijzigd:16 april 2019 12:13

Contact information

Antonius Deusinglaan 1
9713 AV Groningen
The Netherlands