prof. dr. L.H. (Lude) Franke

Full Professor Functional Genomics

prof. dr. L.H. (Lude) Franke


  1. Habitual dietary intake of IBD patients differs from population controls: a case-control study

    Peters, V., Tigchelaar-Feenstra, E. F., Imhann, F., Dekens, J. A. M., Swertz, M. A., Franke, L. H., Wijmenga, C., Weersma, R. K., Alizadeh, B. Z., Dijkstra, G. & Campmans-Kuijpers, M. J. E., 24-Apr-2020, In : European journal of nutrition. 12 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  2. Deconvolution of bulk blood eQTL effects into immune cell subpopulations

    Aguirre-Gamboa, R., de Klein, N., di Tommaso, J., Claringbould, A., Vosa, U., Zorro, M., Chu, X., Bakker, O. O., Borek, Z., Ricano-Ponce, I., Deelen, P., Xu, C., Swertz, M., Jonkers, I., Withoff, S., Joosten, I., Sanna, S., Kumar, V., Koenen, H. J. P. M., Joosten, L. A. B., Netea, M. G., Wijmenga, C., Franke, L. & Li, Y., 19-Feb-2019, In : bioRxiv. 45 p., 548669.

    Research output: Contribution to journalArticleAcademic

  3. Evaluation of commonly used analysis strategies for epigenome- and transcriptome-wide association studies through replication of large-scale population studies

    BIOS Consortium, van Rooij, J., Mandaviya, P. R., Claringbould, A., Felix, J. F., van Dongen, J., Jansen, R., Franke, L., 't Hoen, P. A. C., Heijmans, B. & van Meurs, J. B. J., 14-Nov-2019, In : Genome Biology. 20, 1, 14 p., 235.

    Research output: Contribution to journalArticleAcademicpeer-review

  4. The single-cell eQTLGen consortium

    Van Der Wijst, M. G. P., De Vries, D. H., Groot, H. E., Trynka, G., Hon, C. C., Bonder, M. J., Stegle, O., Nawijn, M. C., Idaghdour, Y., Van Der Harst, P., Ye, C. J., Powell, J., Theis, F. J., Mahfouz, A., Heing, M. & Franke, L., 9-Mar-2020, In : eLife. 9, 21 p., 52155.

    Research output: Contribution to journalArticleAcademicpeer-review

  5. A characterization of cis- and trans-heritability of RNA-Seq-based gene expression

    BIOS Consortium, Ouwens, K. G., Jansen, R., Nivard, M. G., van Dongen, J., Frieser, M. J., Hottenga, J-J., Arindrarto, W., Claringbould, A., van Iterson, M., Mei, H. & Franke, L., Feb-2020, In : European Journal of Human Genetics. 28, 2, p. 253-263 11 p.

    Research output: Contribution to journalArticleAcademicpeer-review

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  1. Data from: Large scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine

    Onderwater, G. L. J. (Creator), Ligthart, L. (Creator), Bot, M. (Creator), Demirkan, A. (Creator), Yang-Fu, J. (Creator), van der Kallen, C. J. H. (Creator), Vijfhuizen, L. S. (Creator), Pool, R. (Creator), Liu, J. (Creator), Vanmolkot, F. H. M. (Creator), Beekman, M. (Creator), Wen, K. (Creator), Amin, N. (Creator), Thesing, C. S. (Creator), Pijpers, J. A. (Creator), Kies, D. A. (Creator), Zielman, R. (Creator), Boer, de, I. (Creator), van Greevenbroek, M. M. J. (Creator), Arts, I. C. W. (Creator), Milaneschi, Y. (Creator), Schram, M. T. (Creator), Dagnelie, P. C. (Creator), Ikram, M. A. (Creator), Ferrari, M. D. (Creator), Goeman, J. (Creator), Slagboom, P. E. (Creator), Stehouwer, C. D. A. (Creator), Boomsma, D. (Creator), Duijn, C. M. V. (Creator), Penninx, B. W. (Creator), 't Hoen, P. A. C. (Creator), Terwindt, G. M. (Creator), van den Maagdenberg, A. M. J. M. (Creator), Dryad Digital Repository, 3-Apr-2019


  2. Data from: Mediation analysis demonstrates that trans-eQTLs are often explained by cis-mediation: a genome-wide analysis among 1,800 South Asians

    Pierce, B. L. (Creator), Tong, L. (Creator), Chen, L. S. (Creator), Rahaman, R. (Creator), Argos, M. (Creator), Jasmine, F. (Creator), Roy, S. (Creator), Paul-Brutus, R. (Creator), Westra, H. J. (Creator), Franke, L. (Creator), Esko, T. (Creator), Zaman, R. (Creator), Islam, T. (Creator), Rahman, M. (Creator), Baron, J. A. (Creator), Kibriya, M. G. (Creator), Ahsan, H. (Creator), University of Groningen, 12-Dec-2014


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  1. Highly Cited Researcher

    Serena Sanna (Recipient), Cisca Wijmenga (Recipient) & Lude Franke (Recipient), 2018

    Prize: National/international honourAcademic

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ID: 303672