prof. dr. L.H. (Lude) Franke
Full Professor Functional Genomics
Research
Publications
Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults
BIOS Consortium, van Dongen, J., Zilhao, N. R., Sugden, K., Hannon, E. J., Mill, J., Caspi, A., Agnew-Blais, J., Arseneault, L., Corcoran, D. L., Moffitt, T. E., Poulton, R., Franke, B. & Boomsma, D., 15-Oct-2019, In : Biological Psychiatry. 86, 8, p. 599-607 9 p.Research output: Contribution to journal › Article › Academic › peer-review
Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine
BBMRI Metabolomics Consortium, 16-Apr-2019, In : Neurology. 92, 16, p. E1899-E1911 13 p.Research output: Contribution to journal › Article › Academic › peer-review
Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits
Porcu, E., Rueger, S., Lepik, K., eQTLgen Consortium & BIOS Consortium, 24-Jul-2019, In : Nature Communications. 10, 12 p., 3300.Research output: Contribution to journal › Article › Academic › peer-review
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk
CommonMind Consortium, Psychiat Genomics Consortium, iPSYCH-GEMS Schizophrenia Working, Huckins, L. M., Dobbyn, A., Ruderfer, D. M., Hoffman, G., Wang, W., Pardinas, A. F., Rajagopal, V. M., Als, T. D., Nguyen, H. T., Girdhar, K., Boocock, J., Roussos, P., Fromer, M., Kramer, R., Purcell, S., Demontis, D., Borglum, A. D., Walters, J. T. R., O'Donovan, M. C., Sullivan, P., Owen, M. J., Devlin, B., Sieberts, S. K., Cox, N. J., Im, H. K., Sklar, P. & Stahl, E. A., Apr-2019, In : Nature Genetics. 51, 4, p. 659-674 18 p.Research output: Contribution to journal › Article › Academic › peer-review
Comprehensive Multiple eQTL Detection and Its Application to GWAS Interpretation
Zeng, B., Lloyd-Jones, L. R., Montgomery, G. W., Metspalu, A., Esko, T., Franke, L., Vosa, U., Claringbould, A., Brigham, K. L., Quyyumi, A. A., Idaghdour, Y., Yang, J., Visscher, P. M., Powell, J. E. & Gibson, G., Jul-2019, In : Genetics. 212, 3, p. 905-918 14 p.Research output: Contribution to journal › Article › Academic › peer-review
Datasets
Data from: Large scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine
Onderwater, G. L. J. (Creator), Ligthart, L. (Creator), Bot, M. (Creator), Demirkan, A. (Creator), Yang-Fu, J. (Creator), van der Kallen, C. J. H. (Creator), Vijfhuizen, L. S. (Creator), Pool, R. (Creator), Liu, J. (Creator), Vanmolkot, F. H. M. (Creator), Beekman, M. (Creator), Wen, K. (Creator), Amin, N. (Creator), Thesing, C. S. (Creator), Pijpers, J. A. (Creator), Kies, D. A. (Creator), Zielman, R. (Creator), Boer, de, I. (Creator), van Greevenbroek, M. M. J. (Creator), Arts, I. C. W. (Creator), Milaneschi, Y. (Creator), Schram, M. T. (Creator), Dagnelie, P. C. (Creator), Ikram, M. A. (Creator), Ferrari, M. D. (Creator), Goeman, J. (Creator), Slagboom, P. E. (Creator), Stehouwer, C. D. A. (Creator), Boomsma, D. (Creator), Duijn, C. M. V. (Creator), Penninx, B. W. (Creator), 't Hoen, P. A. C. (Creator), Terwindt, G. M. (Creator), van den Maagdenberg, A. M. J. M. (Creator), Dryad Digital Repository, 3-Apr-2019
DOI: https://doi.org/10.5061/dryad.p698mn7, http://(bbmri.researchlumc.nl/ atlas
Dataset
Data from: Mediation analysis demonstrates that trans-eQTLs are often explained by cis-mediation: a genome-wide analysis among 1,800 South Asians
Pierce, B. L. (Creator), Tong, L. (Creator), Chen, L. S. (Creator), Rahaman, R. (Creator), Argos, M. (Creator), Jasmine, F. (Creator), Roy, S. (Creator), Paul-Brutus, R. (Creator), Westra, H. J. (Creator), Franke, L. (Creator), Esko, T. (Creator), Zaman, R. (Creator), Islam, T. (Creator), Rahman, M. (Creator), Baron, J. A. (Creator), Kibriya, M. G. (Creator), Ahsan, H. (Creator), University of Groningen, 12-Dec-2014
DOI: https://doi.org/10.5061/dryad.tp097
Dataset
Activities
Ongoing collaboration: bioinformatics analysis of genomic instability
Marcel A. T. M. van Vlugt (Other), Lude Franke (Other), Rudolf Fehrmann (Other)2015 → …Activity: Other › Academic
Prizes
Highly Cited Researcher
Serena Sanna (Recipient), Cisca Wijmenga (Recipient) & Lude Franke (Recipient), 2018
Prize: National/international honour › Academic
ID: 303672