prof. dr. L.H. (Lude) Franke
Full Professor Functional Genomics
Research
Publications
Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals
Folkersen, L., Gustafsson, S., Wang, Q., Hansen, D. H., Hedman, Å. K., Schork, A., Page, K., Zhernakova, D. V., Wu, Y., Peters, J., Eriksson, N., Bergen, S. E., Boutin, T. S., Bretherick, A. D., Enroth, S., Kalnapenkis, A., Gådin, J. R., Suur, B. E., Chen, Y., Matic, L., Gale, J. D., Lee, J., Zhang, W., Quazi, A., Ala-Korpela, M., Choi, S. H., Claringbould, A., Danesh, J., Davey Smith, G., de Masi, F., Elmståhl, S., Engström, G., Fauman, E., Fernandez, C., Franke, L., Franks, P. W., Giedraitis, V., Haley, C., Hamsten, A., Ingason, A., Johansson, Å., Joshi, P. K., Lind, L., Lindgren, C. M., Lubitz, S., Palmer, T., Macdonald-Dunlop, E., Magnusson, M., Melander, O., Michaelsson, K., Morris, A. P., Mägi, R., Nagle, M. W., Nilsson, P. M., Nilsson, J., Orho-Melander, M., Polasek, O., Prins, B., Pålsson, E., Qi, T., Sjögren, M., Sundström, J., Surendran, P., Võsa, U., Werge, T., Wernersson, R., Westra, H-J., Yang, J., Zhernakova, A., Ärnlöv, J., Fu, J., Smith, J. G., Esko, T., Hayward, C., Gyllensten, U., Landen, M., Siegbahn, A., Wilson, J. F., Wallentin, L., Butterworth, A. S., Holmes, M. V., Ingelsson, E. & Mälarstig, A., 16-Oct-2020, In : Nature Metabolism. 2, 10, p. 1135-1148 14 p.Research output: Contribution to journal › Article › Academic › peer-review
Mendelian randomization while jointly modeling cis genetics identifies causal relationships between gene expression and lipids
BIOS Consortium & Franke, L., 1-Oct-2020, In : Nature Communications. 11, 1, 12 p., 4930.Research output: Contribution to journal › Article › Academic › peer-review
An epigenome-wide association study identifies multiple DNA methylation markers of exposure to endocrine disruptors
BIOS Consortium, Lu, X., Fraszczyk, E., van der Meer, T. P., van Faassen, M., Bloks, V. W., Kema, I. P., van Beek, A. P., Li, S., Franke, L., Westra, H-J., Xu, X., Huo, X., Snieder, H., Wolffenbuttel, B. H. R. & van Vliet-Ostaptchouk, J. V., 8-Sep-2020, In : Environment international. 144, 8 p., 106016.Research output: Contribution to journal › Article › Academic › peer-review
Lack of Association Between Genetic Variants at ACE2 and TMPRSS2 Genes Involved in SARS-CoV-2 Infection and Human Quantitative Phenotypes
Lifelines Cohort Study, Lopera Maya, E. A., van der Graaf, A., Lanting, P., van der Geest, M., Fu, J., Swertz, M., Franke, L., Wijmenga, C., Deelen, P., Zhernakova, A. & Sanna, S., 8-Jun-2020, In : Frontiers in Genetics. 11, 10 p., 613.Research output: Contribution to journal › Article › Academic › peer-review
Predicted efficacy of a pharmacogenetic passport for inflammatory bowel disease
Bangma, A., Voskuil, M. D., Uniken Venema, W. T. C., Brugge, H., Hu, S., Lanting, P., Franke, L., Dijkstra, G., Festen, E. A. M. & Weersma, R. K., Jun-2020, In : Alimentary Pharmacology & Therapeutics. 51, 11, p. 1105-1115 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Datasets
Data from: Large scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine
Onderwater, G. L. J. (Creator), Ligthart, L. (Creator), Bot, M. (Creator), Demirkan, A. (Creator), Yang-Fu, J. (Creator), van der Kallen, C. J. H. (Creator), Vijfhuizen, L. S. (Creator), Pool, R. (Creator), Liu, J. (Creator), Vanmolkot, F. H. M. (Creator), Beekman, M. (Creator), Wen, K. (Creator), Amin, N. (Creator), Thesing, C. S. (Creator), Pijpers, J. A. (Creator), Kies, D. A. (Creator), Zielman, R. (Creator), Boer, de, I. (Creator), van Greevenbroek, M. M. J. (Creator), Arts, I. C. W. (Creator), Milaneschi, Y. (Creator), Schram, M. T. (Creator), Dagnelie, P. C. (Creator), Franke, L. (Contributor), Ikram, M. A. (Creator), Ferrari, M. D. (Creator), Goeman, J. (Creator), Slagboom, P. E. (Creator), Wijmenga, C. (Contributor), Stehouwer, C. D. A. (Creator), Boomsma, D. (Creator), Duijn, C. M. V. (Creator), Penninx, B. W. (Creator), 't Hoen, P. A. C. (Creator), Terwindt, G. M. (Creator) & van den Maagdenberg, A. M. J. M. (Creator), Dryad Digital Repository, 3-Apr-2019
DOI: https://doi.org/10.5061/dryad.p698mn7, http://(bbmri.researchlumc.nl/ atlas
Dataset
Data from: Mediation analysis demonstrates that trans-eQTLs are often explained by cis-mediation: a genome-wide analysis among 1,800 South Asians
Pierce, B. L. (Creator), Tong, L. (Creator), Chen, L. S. (Creator), Rahaman, R. (Creator), Argos, M. (Creator), Jasmine, F. (Creator), Roy, S. (Creator), Paul-Brutus, R. (Creator), Westra, H. J. (Creator), Franke, L. (Creator), Esko, T. (Creator), Zaman, R. (Creator), Islam, T. (Creator), Rahman, M. (Creator), Baron, J. A. (Creator), Kibriya, M. G. (Creator) & Ahsan, H. (Creator), University of Groningen, 12-Dec-2014
DOI: https://doi.org/10.5061/dryad.tp097
Dataset
Prizes
Highly Cited Researcher
Serena Sanna (Recipient), Wijmenga, Cisca (Recipient) & Franke, Lude (Recipient), 2018
Prize: National/international honour › Academic
Activities
Ongoing collaboration: bioinformatics analysis of genomic instability
Marcel A. T. M. van Vlugt (Other), Lude Franke (Other) & Rudolf Fehrmann (Other)
2015 → …Activity: Other › Academic
Press / Media
Friezen vertellen over de lange nasleep van een coronabesmetting
29/11/2020
1 Media contribution
Press/Media: Other › Popular
ID: 303672