prof. dr. L.H. (Lude) Franke

Full Professor Functional Genomics

Faculty of Medical Sciences

Telephone:

+31 50 361 7100

E-mail:

l.h.franke umcg.nl

Homepage ORCID Research Portal

Publications

Lipid-induced transcriptomic changes in blood link to lipid metabolism and allergic response

BIOS Consortium , Dekkers, K. F. , Slieker, R. C. , Ioan-Facsinay, A. , van Iterson, M. , Ikram, M. A. , van Greevenbroek, M. M. J. , Veldink, J. H. , Franke, L. , Boomsma, D. I. , Slagboom, P. E. , Jukema, J. W. & Heijmans, B. T. , 1-Feb-2023 , In: Nature Communications. 14 , 9 p. , 544.

Research output: Contribution to journal › Article › Academic › peer-review

Semiautomatic translation of medicine usage data (in Dutch, free-text) from Lifelines COVID-19 questionnaires to ATC codes

Kellmann, A. , Lanting, P. , Franke, L. H. , van Enckevort, E. & Swertz, M. A. , 2023 , In: Database-The journal of biological databases and curation.

Research output: Contribution to journal › Article › Academic › peer-review

A first update on mapping the human genetic architecture of COVID-19

COVID-19 Host Genetics Initiative , 4-Aug-2022 , In: Nature. 608 , p. E1–E10 13 p.

Research output: Contribution to journal › Editorial › Academic › peer-review

Age-dependent sex differences in cardiometabolic risk factors

Lifelines Cohort Study , Zhernakova, D. V. , Sinha, T. , Andreu Sánchez, S. , Prins, J. , Kurilshikov, A. , Balder, J-W. , Sanna, S. , Franke, L. H. , Kuivenhoven, J. A. , Zhernakova, A. & Fu, J. , Sept-2022 , In: Nature Cardiovascular Research. 1 , p. 844–854 24 p.

Research output: Contribution to journal › Article › Academic › peer-review

Author Correction: Effect of host genetics on the gut microbiome in 7,738 participants of the Dutch Microbiome Project (Nature Genetics, (2022), 54, 2, (143-151), 10.1038/s41588-021-00992-y)

Lifelines Cohort Study, Lopera-Maya, E. A. , Kurilshikov, A. , van der Graaf, A. , Hu, S. , Andreu-Sánchez, S. , Chen, L. , Vila, A. V. , Gacesa, R. , Sinha, T. , Collij, V. , Klaassen, M. A. Y., Bolte, L. A. , Gois, M. F. B. , Neerincx, P. B. T. , Swertz, M. A. , Harmsen, H. J. M. , Wijmenga, C. , Fu, J. , Weersma, R. K. , & 2 others Zhernakova, A. & Sanna, S. , 1-Sept-2022 , In: Nature genetics. 54 , 9 , p. 1448 1 p.

Research output: Contribution to journal › Erratum

Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology (vol 53, pg 1636, 2021)

SLALOM Consortium, PARALS Consortium, SLAGEN Consortium, SLAP Consortium, van Rheenen, W., van der Spek, R. A. A., Bakker, M. K., van Vugt, J. J. F. A., Hop, P. J., Zwamborn, R. A. J., de Klein, N. , Westra, H-J. , Bakker, O. B. , Deelen, P. , Shireby, G., Hannon, E., Moisse, M., Baird, D., Restuadi, R., Dolzhenko, E., & 34 others Dekker, A. M. , Gawor, K. , Westeneng, H-J. , Tazelaar, G. H. P. , van Eijk, K. R. , Kooyman, M. , Byrne, R. P. , Doherty, M. , Heverin, M. , Al Khleifat, A. , Iacoangeli, A. , Shatunov, A. , Ticozzi, N. , Cooper-Knock, J. , Smith, B. N. , Gromicho, M. , Chandran, S. , Pal, S. , Morrison, K. E. , Shaw, P. J. , Hardy, J. , Orrell, R. W. , Sendtner, M. , Meyer, T. , Basak, N. , van der Kooi, A. J. , Ratti, A. , Fogh, I. , Gellera, C. , Lauria, G. , Corti, S. , Kraft, J. , Franke, L. & Veldink, J. H. , Mar-2022 , In: Nature genetics. 54 , 3 , p. 361-361 1 p.

Research output: Contribution to journal › Erratum

Effect of host genetics on the gut microbiome in 7,738 participants of the Dutch Microbiome Project

Lopera-Maya, E. A. , Kurilshikov, A. , van der Graaf, A. , Hu, S. , Lifelines Cohort Study, Andreu-Sánchez, S. , Chen, L. , Vila, A. V. , Gacesa, R. , Sinha, T. , Collij, V. , Klaassen, M. A. Y., Bolte, L. A. , Brandao Gois, M. F. , Neerincx, P. B. T. , Swertz, M. A. , Harmsen, H. J. M. , Wijmenga, C. , Fu, J. , Weersma, R. K. , & 2 others Zhernakova, A. & Sanna, S. , Feb-2022 , In: Nature genetics. 54 , p. 143-151 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

Functional genomics analysis identifies T and NK cell activation as a driver of epigenetic clock progression

BIOS Consortium , Dec-2022 , In: Genome Biology. 23 , 1 , p. 24

Research output: Contribution to journal › Article › Academic › peer-review

Genetic, parental and lifestyle factors influence telomere length

Andreu-Sánchez, S. , Aubert, G. , Ripoll-Cladellas, A. , Henkelman, S. , Zhernakova, D. V. , Sinha, T. , Kurilshikov, A. , Cenit, M. C. , Jan Bonder, M. , Franke, L. , Wijmenga, C. , Fu, J. , van der Wijst, M. G. P. , Melé, M. , Lansdorp, P. & Zhernakova, A. , 9-Jun-2022 , (E-pub ahead of print) In: Communications biology. 5 , 1 , 13 p. , 565.

Research output: Contribution to journal › Article › Academic › peer-review

Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS

BIOS Consortium, Brain MEND Consortium, Hop, P. J., Zwamborn, R. A. J., Hannon, E., Shireby, G. L., Nabais, M. F., Walker, E. M., van Rheenen, W., van Vugt, J. J. F. A., Dekker, A. M., Westeneng, H. J., Tazelaar, G. H. P., van Eijk, K. R., Moisse, M., Baird, D., Al Khleifat, A., Iacoangeli, A., Ticozzi, N., Ratti, A., & 25 others Cooper-Knock, J. , Morrison, K. E. , Shaw, P. J. , Basak, A. N. , Chiò, A. , Calvo, A. , Moglia, C. , Canosa, A. , Brunetti, M. , Grassano, M. , Gotkine, M. , Lerner, Y. , Zabari, M. , Vourc'H, P. , Corcia, P. , Couratier, P. , Mora Pardina, J. S. , Salas, T. , Dion, P. , Ross, J. P. , Henderson, R. D. , Mathers, S. , McCombe, P. A. , Needham, M. & Veldink, J. H. , 23-Feb-2022 , In: Science Translational Medicine. 14 , 633 , 16 p. , eabj0264.

Research output: Contribution to journal › Article › Academic › peer-review