prof. dr. L.H. (Lude) Franke

Associate Professor

Research

Publications
  1. Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits

    Porcu, E., Rueger, S., Lepik, K., eQTLgen Consortium & BIOS Consortium, 24-Jul-2019, In : Nature Communications. 10, 12 p., 3300.

    Research output: Contribution to journalArticleAcademicpeer-review

  2. Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

    CommonMind Consortium, Psychiat Genomics Consortium, iPSYCH-GEMS Schizophrenia Working, Huckins, L. M., Dobbyn, A., Ruderfer, D. M., Hoffman, G., Wang, W., Pardinas, A. F., Rajagopal, V. M., Als, T. D., Nguyen, H. T., Girdhar, K., Boocock, J., Roussos, P., Fromer, M., Kramer, R., Purcell, S., Demontis, D., Borglum, A. D., Walters, J. T. R., O'Donovan, M. C., Sullivan, P., Owen, M. J., Devlin, B., Sieberts, S. K., Cox, N. J., Im, H. K., Sklar, P. & Stahl, E. A., Apr-2019, In : Nature Genetics. 51, 4, p. 659-674 18 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  3. Comprehensive Multiple eQTL Detection and Its Application to GWAS Interpretation

    Zeng, B., Lloyd-Jones, L. R., Montgomery, G. W., Metspalu, A., Esko, T., Franke, L., Vosa, U., Claringbould, A., Brigham, K. L., Quyyumi, A. A., Idaghdour, Y., Yang, J., Visscher, P. M., Powell, J. E. & Gibson, G., Jul-2019, In : Genetics. 212, 3, p. 905-918 14 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  4. RNA-Seq in 296 phased trios provides a high-resolution map of genomic imprinting

    GoNL Consortium & BIOS Consortium, 24-Jun-2019, In : BMC Biology. 17, 20 p., 50.

    Research output: Contribution to journalArticleAcademicpeer-review

  5. High-throughput identification of human SNPs affecting regulatory element activity

    van Arensbergen, J., Pagie, L., FitzPatrick, V. D., de Haas, M., Baltissen, M. P., Comoglio, F., van der Weide, R. H., Teunissen, H., Vosa, U., Franke, L., de Wit, E., Vermeulen, M., Bussemaker, H. J. & van Steensel, B., Jul-2019, In : Nature Genetics. 51, 7, p. 1160-+ 13 p.

    Research output: Contribution to journalArticleAcademicpeer-review

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Datasets
  1. Data from: Mediation analysis demonstrates that trans-eQTLs are often explained by cis-mediation: a genome-wide analysis among 1,800 South Asians

    Pierce, B. L. (Creator), Tong, L. (Creator), Chen, L. S. (Creator), Rahaman, R. (Creator), Argos, M. (Creator), Jasmine, F. (Creator), Roy, S. (Creator), Paul-Brutus, R. (Creator), Westra, H. J. (Creator), Franke, L. (Creator), Esko, T. (Creator), Zaman, R. (Creator), Islam, T. (Creator), Rahman, M. (Creator), Baron, J. A. (Creator), Kibriya, M. G. (Creator), Ahsan, H. (Creator), University of Groningen, 12-Dec-2014

    Dataset

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Prizes
  1. Highly Cited Researcher

    Serena Sanna (Recipient), Cisca Wijmenga (Recipient) & Lude Franke (Recipient), 2018

    Prize: National/international honourAcademic

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