prof. dr. L.H. (Lude) Franke
Full Professor Functional Genomics
Research
Publications
Habitual dietary intake of IBD patients differs from population controls: a case-control study
Peters, V., Tigchelaar-Feenstra, E. F., Imhann, F., Dekens, J. A. M., Swertz, M. A., Franke, L. H., Wijmenga, C., Weersma, R. K., Alizadeh, B. Z., Dijkstra, G. & Campmans-Kuijpers, M. J. E., 24-Apr-2020, In : European journal of nutrition. 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Deconvolution of bulk blood eQTL effects into immune cell subpopulations
Aguirre-Gamboa, R., de Klein, N., di Tommaso, J., Claringbould, A., Vosa, U., Zorro, M., Chu, X., Bakker, O. O., Borek, Z., Ricano-Ponce, I., Deelen, P., Xu, C., Swertz, M., Jonkers, I., Withoff, S., Joosten, I., Sanna, S., Kumar, V., Koenen, H. J. P. M., Joosten, L. A. B., Netea, M. G., Wijmenga, C., Franke, L. & Li, Y., 19-Feb-2019, In : bioRxiv. 45 p., 548669.Research output: Contribution to journal › Article › Academic
Evaluation of commonly used analysis strategies for epigenome- and transcriptome-wide association studies through replication of large-scale population studies
BIOS Consortium, van Rooij, J., Mandaviya, P. R., Claringbould, A., Felix, J. F., van Dongen, J., Jansen, R., Franke, L., 't Hoen, P. A. C., Heijmans, B. & van Meurs, J. B. J., 14-Nov-2019, In : Genome Biology. 20, 1, 14 p., 235.Research output: Contribution to journal › Article › Academic › peer-review
The single-cell eQTLGen consortium
Van Der Wijst, M. G. P., De Vries, D. H., Groot, H. E., Trynka, G., Hon, C. C., Bonder, M. J., Stegle, O., Nawijn, M. C., Idaghdour, Y., Van Der Harst, P., Ye, C. J., Powell, J., Theis, F. J., Mahfouz, A., Heing, M. & Franke, L., 9-Mar-2020, In : eLife. 9, 21 p., 52155.Research output: Contribution to journal › Article › Academic › peer-review
A characterization of cis- and trans-heritability of RNA-Seq-based gene expression
BIOS Consortium, Ouwens, K. G., Jansen, R., Nivard, M. G., van Dongen, J., Frieser, M. J., Hottenga, J-J., Arindrarto, W., Claringbould, A., van Iterson, M., Mei, H. & Franke, L., Feb-2020, In : European Journal of Human Genetics. 28, 2, p. 253-263 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Datasets
Data from: Large scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine
Onderwater, G. L. J. (Creator), Ligthart, L. (Creator), Bot, M. (Creator), Demirkan, A. (Creator), Yang-Fu, J. (Creator), van der Kallen, C. J. H. (Creator), Vijfhuizen, L. S. (Creator), Pool, R. (Creator), Liu, J. (Creator), Vanmolkot, F. H. M. (Creator), Beekman, M. (Creator), Wen, K. (Creator), Amin, N. (Creator), Thesing, C. S. (Creator), Pijpers, J. A. (Creator), Kies, D. A. (Creator), Zielman, R. (Creator), Boer, de, I. (Creator), van Greevenbroek, M. M. J. (Creator), Arts, I. C. W. (Creator), Milaneschi, Y. (Creator), Schram, M. T. (Creator), Dagnelie, P. C. (Creator), Ikram, M. A. (Creator), Ferrari, M. D. (Creator), Goeman, J. (Creator), Slagboom, P. E. (Creator), Stehouwer, C. D. A. (Creator), Boomsma, D. (Creator), Duijn, C. M. V. (Creator), Penninx, B. W. (Creator), 't Hoen, P. A. C. (Creator), Terwindt, G. M. (Creator), van den Maagdenberg, A. M. J. M. (Creator), Dryad Digital Repository, 3-Apr-2019
DOI: https://doi.org/10.5061/dryad.p698mn7, http://(bbmri.researchlumc.nl/ atlas
Dataset
Data from: Mediation analysis demonstrates that trans-eQTLs are often explained by cis-mediation: a genome-wide analysis among 1,800 South Asians
Pierce, B. L. (Creator), Tong, L. (Creator), Chen, L. S. (Creator), Rahaman, R. (Creator), Argos, M. (Creator), Jasmine, F. (Creator), Roy, S. (Creator), Paul-Brutus, R. (Creator), Westra, H. J. (Creator), Franke, L. (Creator), Esko, T. (Creator), Zaman, R. (Creator), Islam, T. (Creator), Rahman, M. (Creator), Baron, J. A. (Creator), Kibriya, M. G. (Creator), Ahsan, H. (Creator), University of Groningen, 12-Dec-2014
DOI: https://doi.org/10.5061/dryad.tp097
Dataset
Activities
Ongoing collaboration: bioinformatics analysis of genomic instability
Marcel A. T. M. van Vlugt (Other), Lude Franke (Other), Rudolf Fehrmann (Other)2015 → …Activity: Other › Academic
Prizes
Highly Cited Researcher
Serena Sanna (Recipient), Cisca Wijmenga (Recipient) & Lude Franke (Recipient), 2018
Prize: National/international honour › Academic
ID: 303672