prof. dr. L.H. (Lude) Franke

Full Professor Functional Genomics

prof. dr. L.H. (Lude) Franke
E-mail:
l.h.franke umcg.nl

Research

Publications
  1. Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

    Folkersen, L., Gustafsson, S., Wang, Q., Hansen, D. H., Hedman, Å. K., Schork, A., Page, K., Zhernakova, D. V., Wu, Y., Peters, J., Eriksson, N., Bergen, S. E., Boutin, T. S., Bretherick, A. D., Enroth, S., Kalnapenkis, A., Gådin, J. R., Suur, B. E., Chen, Y., Matic, L., Gale, J. D., Lee, J., Zhang, W., Quazi, A., Ala-Korpela, M., Choi, S. H., Claringbould, A., Danesh, J., Davey Smith, G., de Masi, F., Elmståhl, S., Engström, G., Fauman, E., Fernandez, C., Franke, L., Franks, P. W., Giedraitis, V., Haley, C., Hamsten, A., Ingason, A., Johansson, Å., Joshi, P. K., Lind, L., Lindgren, C. M., Lubitz, S., Palmer, T., Macdonald-Dunlop, E., Magnusson, M., Melander, O., Michaelsson, K., Morris, A. P., Mägi, R., Nagle, M. W., Nilsson, P. M., Nilsson, J., Orho-Melander, M., Polasek, O., Prins, B., Pålsson, E., Qi, T., Sjögren, M., Sundström, J., Surendran, P., Võsa, U., Werge, T., Wernersson, R., Westra, H-J., Yang, J., Zhernakova, A., Ärnlöv, J., Fu, J., Smith, J. G., Esko, T., Hayward, C., Gyllensten, U., Landen, M., Siegbahn, A., Wilson, J. F., Wallentin, L., Butterworth, A. S., Holmes, M. V., Ingelsson, E. & Mälarstig, A., 16-Oct-2020, In : Nature Metabolism. 2, 10, p. 1135-1148 14 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  2. Mendelian randomization while jointly modeling cis genetics identifies causal relationships between gene expression and lipids

    BIOS Consortium & Franke, L., 1-Oct-2020, In : Nature Communications. 11, 1, 12 p., 4930.

    Research output: Contribution to journalArticleAcademicpeer-review

  3. An epigenome-wide association study identifies multiple DNA methylation markers of exposure to endocrine disruptors

    BIOS Consortium, Lu, X., Fraszczyk, E., van der Meer, T. P., van Faassen, M., Bloks, V. W., Kema, I. P., van Beek, A. P., Li, S., Franke, L., Westra, H-J., Xu, X., Huo, X., Snieder, H., Wolffenbuttel, B. H. R. & van Vliet-Ostaptchouk, J. V., 8-Sep-2020, In : Environment international. 144, 8 p., 106016.

    Research output: Contribution to journalArticleAcademicpeer-review

  4. Lack of Association Between Genetic Variants at ACE2 and TMPRSS2 Genes Involved in SARS-CoV-2 Infection and Human Quantitative Phenotypes

    Lifelines Cohort Study, Lopera Maya, E. A., van der Graaf, A., Lanting, P., van der Geest, M., Fu, J., Swertz, M., Franke, L., Wijmenga, C., Deelen, P., Zhernakova, A. & Sanna, S., 8-Jun-2020, In : Frontiers in Genetics. 11, 10 p., 613.

    Research output: Contribution to journalArticleAcademicpeer-review

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Datasets
  1. Data from: Large scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine

    Onderwater, G. L. J. (Creator), Ligthart, L. (Creator), Bot, M. (Creator), Demirkan, A. (Creator), Yang-Fu, J. (Creator), van der Kallen, C. J. H. (Creator), Vijfhuizen, L. S. (Creator), Pool, R. (Creator), Liu, J. (Creator), Vanmolkot, F. H. M. (Creator), Beekman, M. (Creator), Wen, K. (Creator), Amin, N. (Creator), Thesing, C. S. (Creator), Pijpers, J. A. (Creator), Kies, D. A. (Creator), Zielman, R. (Creator), Boer, de, I. (Creator), van Greevenbroek, M. M. J. (Creator), Arts, I. C. W. (Creator), Milaneschi, Y. (Creator), Schram, M. T. (Creator), Dagnelie, P. C. (Creator), Franke, L. (Contributor), Ikram, M. A. (Creator), Ferrari, M. D. (Creator), Goeman, J. (Creator), Slagboom, P. E. (Creator), Wijmenga, C. (Contributor), Stehouwer, C. D. A. (Creator), Boomsma, D. (Creator), Duijn, C. M. V. (Creator), Penninx, B. W. (Creator), 't Hoen, P. A. C. (Creator), Terwindt, G. M. (Creator) & van den Maagdenberg, A. M. J. M. (Creator), Dryad Digital Repository, 3-Apr-2019

    Dataset

  2. Data from: Mediation analysis demonstrates that trans-eQTLs are often explained by cis-mediation: a genome-wide analysis among 1,800 South Asians

    Pierce, B. L. (Creator), Tong, L. (Creator), Chen, L. S. (Creator), Rahaman, R. (Creator), Argos, M. (Creator), Jasmine, F. (Creator), Roy, S. (Creator), Paul-Brutus, R. (Creator), Westra, H. J. (Creator), Franke, L. (Creator), Esko, T. (Creator), Zaman, R. (Creator), Islam, T. (Creator), Rahman, M. (Creator), Baron, J. A. (Creator), Kibriya, M. G. (Creator) & Ahsan, H. (Creator), University of Groningen, 12-Dec-2014

    Dataset

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Prizes
  1. Highly Cited Researcher

    Serena Sanna (Recipient), Wijmenga, Cisca (Recipient) & Franke, Lude (Recipient), 2018

    Prize: National/international honourAcademic

View all (1) »

Press / Media
  1. Friezen vertellen over de lange nasleep van een coronabesmetting

    Lude Franke

    29/11/2020

    1 Media contribution

    Press/Media: OtherPopular

View all (1) »

ID: 303672