prof. dr. L.H. (Lude) Franke

Full Professor Functional Genomics

Faculty of Medical Sciences

Telephone:

+31 50 361 7100

E-mail:

l.h.franke umcg.nl

Homepage ORCID Research Portal

Publications

Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology (vol 53, pg 1636, 2021)

SLALOM Consortium, PARALS Consortium, SLAGEN Consortium, SLAP Consortium, van Rheenen, W., van der Spek, R. A. A., Bakker, M. K., van Vugt, J. J. F. A., Hop, P. J., Zwamborn, R. A. J., de Klein, N. , Westra, H-J. , Bakker, O. B. , Deelen, P. , Shireby, G., Hannon, E., Moisse, M., Baird, D., Restuadi, R., Dolzhenko, E.& 34 others , Dekker, A. M. , Gawor, K. , Westeneng, H-J. , Tazelaar, G. H. P. , van Eijk, K. R. , Kooyman, M. , Byrne, R. P. , Doherty, M. , Heverin, M. , Al Khleifat, A. , Iacoangeli, A. , Shatunov, A. , Ticozzi, N. , Cooper-Knock, J. , Smith, B. N. , Gromicho, M. , Chandran, S. , Pal, S. , Morrison, K. E. , Shaw, P. J. , Hardy, J. , Orrell, R. W. , Sendtner, M. , Meyer, T. , Basak, N. , van der Kooi, A. J. , Ratti, A. , Fogh, I. , Gellera, C. , Lauria, G. , Corti, S. , Kraft, J. , Franke, L. & Veldink, J. H. , Mar-2022 , In: Nature genetics. 54 , 3 , p. 361-361 1 p.

Research output: Contribution to journal › Article › Academic › peer-review

Functional genomics analysis identifies T and NK cell activation as a driver of epigenetic clock progression

BIOS Consortium , Dec-2022 , In: Genome Biology. 23 , 1 , p. 24

Research output: Contribution to journal › Article › Academic › peer-review

Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS

BIOS Consortium, Brain MEND Consortium, Hop, P. J., Zwamborn, R. A. J., Hannon, E., Shireby, G. L., Nabais, M. F., Walker, E. M., van Rheenen, W., van Vugt, J. J. F. A., Dekker, A. M., Westeneng, H. J., Tazelaar, G. H. P., van Eijk, K. R., Moisse, M., Baird, D., Al Khleifat, A., Iacoangeli, A., Ticozzi, N., Ratti, A.& 25 others , Cooper-Knock, J. , Morrison, K. E. , Shaw, P. J. , Basak, A. N. , Chiò, A. , Calvo, A. , Moglia, C. , Canosa, A. , Brunetti, M. , Grassano, M. , Gotkine, M. , Lerner, Y. , Zabari, M. , Vourc'H, P. , Corcia, P. , Couratier, P. , Mora Pardina, J. S. , Salas, T. , Dion, P. , Ross, J. P. , Henderson, R. D. , Mathers, S. , McCombe, P. A. , Needham, M. & Veldink, J. H. , 23-Feb-2022 , In: Science Translational Medicine. 14 , 633 , 16 p. , eabj0264.

Research output: Contribution to journal › Article › Academic › peer-review

Idéfix: identifying accidental sample mix-ups in biobanks using polygenic scores

Lifelines Cohort Study , Warmerdam, R. , Lanting, P. , Deelen, P. & Franke, L. , 15-Feb-2022 , In: Bioinformatics (Oxford, England). 38 , 4 , p. 1059–1066 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

Impact of the COVID-19 pandemic on adults with moderate-to-severe atopic dermatitis in the Dutch general population

Lifelines Corona Research initiative, Zhang, J. , Loman, L. , Kamphuis, E. , Schuttelaar, M. L. A. , Boezen, H. M. , Mierau, J. , Franke, H. L. , Dekens, J. , Deelen, P. , Lanting, P. , Vonk, J. M. , Nolte, I. M. , Ori, A. P. S. , Claringbould, A. , Boulogne, F. , Dijkema, M. X. L., Wiersma, H. H. , Warmerdam, R. , Jankipersadsing, S. A. & 1 others , van Blokland, I. , Mar-2022 , In: JAAD international. 6 , p. 86-93 8 p.

Research output: Contribution to journal › Letter › Academic › peer-review

Translational insights from single-cell technologies across the cardiovascular disease continuum

van Blokland, I. V. , Groot, H. E. , Franke, L. H. , van der Wijst, M. G. P. & van der Harst, P. , Apr-2022 , In: TRENDS IN CARDIOVASCULAR MEDICINE. 32 , 3 , p. 127-135 9 p.

Research output: Contribution to journal › Review article › Academic › peer-review

Association and genetic overlap between clinical chemistry tests and migraine

The International Headache Genetics Consortium (IHGC) , Tanha, H. M. , Martin, N. G. , Whitfield, J. B. & Nyholt, D. R. , Oct-2021 , In: Cephalalgia. 41 , 11-12 , p. 1208-1221 14 p.

Research output: Contribution to journal › Article › Academic › peer-review

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

SLALOM Consortium, PARALS Consortium, SLAGEN Consortium, SLAP Consortium, van Rheenen, W., van der Spek, R. A. A., Bakker, M. K., van Vugt, J. J. F. A., Hop, P. J., Zwamborn, R. A. J., de Klein, N. , Westra, H. J. , Bakker, O. B. , Deelen, P. , Shireby, G., Hannon, E., Moisse, M., Baird, D., Restuadi, R., Dolzhenko, E.& 34 others , Dekker, A. M. , Gawor, K. , Westeneng, H. J. , Tazelaar, G. H. P. , van Eijk, K. R. , Kooyman, M. , Byrne, R. P. , Doherty, M. , Heverin, M. , Al Khleifat, A. , Iacoangeli, A. , Shatunov, A. , Ticozzi, N. , Cooper-Knock, J. , Smith, B. N. , Gromicho, M. , Chandran, S. , Pal, S. , Morrison, K. E. , Shaw, P. J. , Hardy, J. , Orrell, R. W. , Sendtner, M. , Meyer, T. , Başak, N. , van der Kooi, A. J. , Ratti, A. , Fogh, I. , Gellera, C. , Lauria, G. , Corti, S. , Cereda, C. , Franke, L. & Veldink, J. H. , 1-Dec-2021 , In: Nature genetics. 53 , 12 , p. 1636-1648 13 p.

Research output: Contribution to journal › Article › Academic › peer-review

Correction for both common and rare cell types in blood is important to identify genes that correlate with age

BIOS Consortium , Pellegrino-Coppola, D. , Claringbould, A. , Stutvoet, M. , Boomsma, D. I. , Ikram, M. A. , Slagboom, P. E. , Westra, H-J. & Franke, L. , 15-Mar-2021 , In: BMC Genomics. 22 , 1 , 12 p. , 184.

Research output: Contribution to journal › Article › Academic › peer-review

DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan

BIOS Consortium, van Dongen, J., Hagenbeek, F. A., Suderman, M., Roetman, P. J., Sugden, K., Chiocchetti, A. G., Ismail, K., Mulder, R. H., Hafferty, J. D., Adams, M. J., Walker, R. M., Morris, S. W., Lahti, J., Küpers, L. K., Escaramis, G., Alemany, S., Jan Bonder, M. , Meijer, M., Ip, H. F.& 31 others , Jansen, R. , Baselmans, B. M. L. , Parmar, P. , Lowry, E. , Streit, F. , Sirignano, L. , Send, T. S. , Frank, J. , Jylhävä, J. , Wang, Y. , Mishra, P. P. , Colins, O. F. , Corcoran, D. L. , Poulton, R. , Mill, J. , Hannon, E. , Arseneault, L. , Korhonen, T. , Vuoksimaa, E. , Felix, J. F. , Bakermans-Kranenburg, M. J. , Campbell, A. , Czamara, D. , Binder, E. , Corpeleijn, E. , Gonzalez, J. R. , Grazuleviciene, R. , van der Meer, D. , Davies, G. E. , Snieder, H. & Franke, L. , 2021 , In: Molecular Psychiatry. 26 , p. 2148-2162 15 p.

Research output: Contribution to journal › Article › Academic › peer-review