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University Medical Center Groningen

dr. J.L. (Joost) Kluiver

Postdoc
Research interests Publicaties Pers/media

Research interests

Over the last decade it has become clear that non-coding RNAs are important players in virtually all physiological processes. Deregulation of non-coding RNAs contributes to diseases including cancer.

In our studies we focus on understanding how small and long non-coding RNAs contribute to the pathogenesis of B-cell lymphoma. These include studies on MYC –regulated miRNAs and lncRNAs, miRNA-lncRNA interactions and the role of lncRNAs in epigenetics.

 

Keywords: B-cell lymphoma, non-coding RNAs, microRNA, lncRNAs

Publicaties

An Unexpected Finding of a PTPN11 Germline Mutation in a Patient With a Melanocytic Lesion With a Somatic MAP2K1 Mutation: Coincidence or Not?

van der Woude, S., Klein Wassink-Ruiter, J. S., Kluiver, J., de Jonge, M. & Diercks, G. F. H., jan.-2025, In: Journal of Cutaneous Pathology. 52, 1, blz. 20-23 4 blz.

Onderzoeksoutput › › peer review

miRNA-dependent resistance mechanisms to anti-hormonal therapies in estrogen receptor-positive breast cancer patients

Al Hashami, Z. S., van der Vegt, B., Mourits, M. J. E., Kluiver, J. & van den Berg, A., 20-mrt.-2025, In: Molecular therapy. Oncology. 33, 1, 13 blz., 200941.

Onderzoeksoutput › peer review

Molecular profiling of cell-free DNA from classic Hodgkin lymphoma patients identifies potential prognostic clusters and corresponds with disease dynamics

Veltmaat, N., Tan, G.-W., Zhong, Y., Teesink, S., Terpstra, M., Bult, J., Nijland, M., Kluiver, J., Diepstra, A., van den Berg, A. & Plattel, W. J., 8-apr.-2025, (E-pub ahead of print) In: Annals of Hematology. 12 blz.

Onderzoeksoutput › › peer review

Circular ZDHHC11 supports Burkitt lymphoma growth independent of its miR-150 binding capacity

Liu, Y., Zhao, X., Seitz, A., Hooijsma, A. A., Ravanbakhsh, R., Sheveleva, S., de Jong, D., Koerts, J., Dzikiewicz-Krawczyk, A., van den Berg, A., Ziel-Swier, L. J. Y. M. & Kluiver, J., 16-apr.-2024, In: Scientific Reports. 14, 9 blz., 8730.

Onderzoeksoutput › › peer review

Core regions in immunoglobulin heavy chain enhancers essential for survival of non-Hodgkin lymphoma cells are identified by a CRISPR interference screen

Kasprzyk, M. E., Sura, W., Podralska, M., Kazimierska, M., Seitz, A., Łosiewski, W., Woźniak, T., Guikema, J. E. J., Diepstra, A., Kluiver, J., Van den Berg, A., Rozwadowska, N. & Dzikiewicz-Krawczyk, A., dec.-2024, In: Haematologica. 109, 12, blz. 4007-4020 14 blz.

Onderzoeksoutput › › peer review

Detection of circulating tumor DNA in plasma of patients with primary CNS lymphoma by digital droplet PCR

Zhong, Y., Tan, G. W., Bult, J., Veltmaat, N., Plattel, W., Kluiver, J., Enting, R., Diepstra, A., van den Berg, A. & Nijland, M., 2-apr.-2024, In: BMC Cancer. 24, 6 blz., 407.

Onderzoeksoutput › › peer review

Inhibition of the glutamate-cysteine ligase catalytic subunit with buthionine sulfoximine enhances the cytotoxic effect of doxorubicin and cyclophosphamide in Burkitt lymphoma cells

Kazimierska, M., Leśniewska, A., Bakker, A., Diepstra, A., Kasprzyk, M. E., Podralska, M., Rassek, K., Kluiver, J., van den Berg, A., Rozwadowska, N. & Dzikiewicz-Krawczyk, A., feb.-2024, In: Journal of Applied Genetics. 65, blz. 95–101 7 blz.

Onderzoeksoutput › › peer review

Molecular Tumor Board of the University Medical Center Groningen (UMCG-MTB): outcome of patients with rare or complex mutational profiles receiving MTB-advised targeted therapy

de Jager, V. D., Plomp, P., Paats, M. S., van Helvert, S., Elst, A. T., van den Berg, A., Dubbink, H. J., van Geffen, W. H., Zhang, L., Hendriks, L. E. L., Hiltermann, T. J. N., Hiddinga, B. I., Hijmering-Kappelle, L. B. M., Jalving, M., Kluiver, J., Koopman, B., van Kruchten, M., van der Logt, E. M. J., Piet, B. & van Putten, J.& 10 anderen, Reitsma, B. H., Rutgers, S. R., de Vries, M., Stigt, J. A., Groves, M. R., Timens, W., Willems, S. M., van Kempen, L. C., Schuuring, E. & van der Wekken, A. J., nov.-2024, In: ESMO Open. 9, 11, 12 blz., 103966.

Onderzoeksoutput › › peer review

NEAT1 and CHROMR lncRNAs: a promising diagnostic tool for diffuse large B-cell lymphoma especially in elderly patients

Rajabi, A., Saber, A., Kluiver, J., den Berg, A. V., Hosseinpourfeizi, M. A. & Safaralizadeh, R., 17-aug.-2024, In: Biomarkers in medicine. 18, 15-16, blz. 685-693 9 blz.

Onderzoeksoutput › › peer review

Pinpointing Functionally Relevant miRNAs in Classical Hodgkin Lymphoma Pathogenesis

Pan, Y., Cengiz, R., Kluiver, J., Diepstra, A. & Van den Berg, A., 12-mrt.-2024, In: Cancers. 16, 6, 17 blz., 1126.

Onderzoeksoutput › peer review

Pers/media

Receiving funding from Lymph&Co

Kluiver, J.

08/03/2017

Pers / media: Overig ›

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