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How to find us dr. J.L. (Joost) Kluiver

Research interests

Over the last decade it has become clear that non-coding RNAs are important players in virtually all physiological processes. Deregulation of non-coding RNAs contributes to diseases including cancer.

In our studies we focus on understanding how small and long non-coding RNAs contribute to the pathogenesis of B-cell lymphoma. These include studies on MYC –regulated miRNAs and lncRNAs, miRNA-lncRNA interactions and the role of lncRNAs in epigenetics.

 

Keywords: B-cell lymphoma, non-coding RNAs, microRNA, lncRNAs

Publications

Actionability of on-target ALK resistance mutations in patients with non-small cell lung cancer: local experience and review of the literature

Non-small-cell lung cancer infiltrated with chronic myelomonocytic leukaemia: a molecular diagnostic challenge to recognise mixed cancers in a single biopsy

MiR-378a-3p Is Critical for Burkitt Lymphoma Cell Growth

Non-Coding RNAs in Cancer Radiosensitivity: MicroRNAs and lncRNAs as Regulators of Radiation-Induced Signaling Pathways

The miR-26b-5p/KPNA2 Axis Is an Important Regulator of Burkitt Lymphoma Cell Growth

UNMASK

A super-SILAC based proteomics analysis of diffuse large B-cell lymphoma-NOS patient samples to identify new proteins that discriminate GCB and non-GCB lymphomas

AAV8-mediated gene transfer of microRNA-132 improves beta cell function in mice fed a high-fat diet

Age-related gene and miRNA expression changes in airways of healthy individuals

Analysis of primary miRNA processing in normal and malignant B-cells

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Press/media

Receiving funding from Lymph&Co