dr. J.L. (Joost) Kluiver


dr. J.L. (Joost) Kluiver
j.l.kluiver umcg.nl


Research interests

Over the last decade it has become clear that non-coding RNAs are important players in virtually all physiological processes. Deregulation of non-coding RNAs contributes to diseases including cancer.

In our studies we focus on understanding how small and long non-coding RNAs contribute to the pathogenesis of B-cell lymphoma. These include studies on MYC –regulated miRNAs and lncRNAs, miRNA-lncRNA interactions and the role of lncRNAs in epigenetics.


Keywords: B-cell lymphoma, non-coding RNAs, microRNA, lncRNAs

  1. Non-Coding RNAs in Cancer Radiosensitivity: MicroRNAs and lncRNAs as Regulators of Radiation-Induced Signaling Pathways

    Podralska, M., Ciesielska, S., Kluiver, J., van den Berg, A., Dzikiewicz-Krawczyk, A. & Slezak-Prochazka, I., 23-Jun-2020, In : Cancers. 12, 6, 27 p., 1662.

    Research output: Contribution to journalReview articleAcademicpeer-review


    Kluiver, J. & van den Berg, A., 2020

    Research output: Non-textual formSoftwarePopular

  3. The miR-26b-5p/KPNA2 Axis Is an Important Regulator of Burkitt Lymphoma Cell Growth

    Niu, F., Kazimierska, M., Nolte, I. M., Terpstra, M. M., de Jong, D., Koerts, J., van der Sluis, T., Rutgers, B., O'Connell, R. M., Kok, K., van den Berg, A., Dzikiewicz-Krawczyk, A. & Kluiver, J., 4-Jun-2020, In : Cancers. 12, 6, p. 1-20 20 p., 1464.

    Research output: Contribution to journalArticleAcademicpeer-review

  4. Marked TGF-β-regulated miRNA expression changes in both COPD and control lung fibroblasts

    Ong, J., Faiz, A., Timens, W., van den Berge, M., Terpstra, M. M., Kok, K., van den Berg, A., Kluiver, J. & Brandsma, C. A., 3-Dec-2019, In : Scientific Reports. 9, 1, 11 p., 18214.

    Research output: Contribution to journalArticleAcademicpeer-review

  5. Analysis of primary miRNA processing in normal and malignant B-cells

    Slezak-Prochazka, I., Kok, K., Bil, P., Kluiver, J. & van den Berg, A., Jul-2019, In : FEBS Open Bio. 9, p. 245-246 2 p.

    Research output: Contribution to journalMeeting AbstractAcademic

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  1. Funding received from Lymph&Co for lymphoma research

    Joost Kluiver (Recipient), 8-Mar-2017

    Prize: Fellowship awarded competitivelyAcademic

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  1. Non-coding RNAs, a novel layer of complexity in B-cell lymphoma pathogenesis

    Joost Kluiver (Invited speaker)

    Activity: Talk or presentationAcademic

  2. Functional analysis of SNPs associated with Hodgkin lymphoma

    Joost Kluiver (Speaker)

    Activity: Talk or presentationAcademic

  3. Non-coding RNAs as oncogenic components of the MYC-regulatory network in Burkitt lymphoma

    Joost Kluiver (Invited speaker)

    Activity: Talk or presentationAcademic

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Press / Media
  1. Receiving funding from Lymph&Co

    Joost Kluiver


    1 item of Media coverage

    Press/Media: OtherPopular

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