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About us Practical matters How to find us dr. J.L. (Joost) Kluiver

Research interests

Over the last decade it has become clear that non-coding RNAs are important players in virtually all physiological processes. Deregulation of non-coding RNAs contributes to diseases including cancer.

In our studies we focus on understanding how small and long non-coding RNAs contribute to the pathogenesis of B-cell lymphoma. These include studies on MYC –regulated miRNAs and lncRNAs, miRNA-lncRNA interactions and the role of lncRNAs in epigenetics.


Keywords: B-cell lymphoma, non-coding RNAs, microRNA, lncRNAs


A population-based study of transformed marginal zone lymphoma: identifying outcome-related characteristics

CRISPR/Cas9 screen for genome-wide interrogation of essential MYC-bound E-boxes in cancer cells

Genomic profiling of post-transplant lymphoproliferative disorders using cell-free DNA

Long non-coding RNAs associated with transcriptomic signatures and treatment outcome in diffuse large B-cell lymphoma

Proliferation-promoting roles of linear and circular PVT1 are independent of their ability to bind miRNAs in B-cell lymphoma

Actionability of on-target ALK Resistance Mutations in Patients With Non-Small Cell Lung Cancer: Local Experience and Review of the Literature

The lncRNA KTN1-AS1 co-regulates a variety of Myc-target genes and enhances proliferation of Burkitt lymphoma cells

The Role of the MYC/miR-150/MYB/ZDHHC11 Network in Hodgkin Lymphoma and Diffuse Large B-Cell Lymphoma

Non-small-cell lung cancer infiltrated with chronic myelomonocytic leukaemia: a molecular diagnostic challenge to recognise mixed cancers in a single biopsy

MiR-378a-3p Is Critical for Burkitt Lymphoma Cell Growth

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Receiving funding from Lymph&Co