prof. dr. J.H.M. (Anke) van den Berg

Professor: Molecular pathogenesis of malignant B cell lymphoma

prof. dr. J.H.M. (Anke) van den Berg
E-mail:
a.van.den.berg01 umcg.nl

Research

Research interests

I am a clinical molecular biologist at the UMCG and a principal investigator in the Stem cells, Ageing, Leukemia and Lymphoma (SALL) program of the Cancer Research Center Groningen. My main research interest is studying the molecular pathogenesis of B cell Hodgkin and non-Hodgkin lymphoma. The specific fields of interest are focused around genomic aberrations, genetic susceptibility, the role of small and long noncoding RNAs and  the cross-talk between tumor cells and the micro environment.

Publications
  1. Disturbed antigen presentation in classical Hodgkin Lymphoma; implications for immune checkpoint inhibitor therapy

    Nijland, M., Visser, L., Veenstra, R., Kushekhar, K., van Imhoff, G., Berg, van den, A. & Diepstra, A., 20-Oct-2016, In : Haematologica. 101, 1 p., T009.

    Research output: Contribution to journalMeeting AbstractAcademic

  2. ZDHHC11 and ZDHHC11B are critical novel components of the oncogenic MYC-miR-150-MYB network in Burkitt lymphoma

    Dzikiewicz-Krawczyk, A., Kok, K., Slezak-Prochazka, I., Robertus, J-L., Bruining, J., Tayari, M. M., Rutgers, B., de Jong, D., Koerts, J., Seitz, A., Li, J., Tillema, B., Guikema, J., Nolte, I. M., Diepstra, A., Visser, L., Kluiver, J. & van den Berg, A., Jul-2017, In : Leukemia. 31, p. 1470-1473 4 p.

    Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

  3. Long noncoding RNAs as a novel component of the Myc transcriptional network

    Winkle, M., van den Berg, A., Tayari, M., Sietzema, J., Terpstra, M., Kortman, G., de Jong, D., Visser, L., Diepstra, A., Kok, K. & Kluiver, J., Jun-2015, In : The FASEB Journal. 29, 6, p. 2338-2346 9 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  4. miR-24-3p Is Overexpressed in Hodgkin Lymphoma and Protects Hodgkin and Reed-Sternberg Cells from Apoptosis

    Yuan, Y., Kluiver, J., Koerts, J., de Jong, D., Rutgers, B., Abdul Razak, F. R., Terpstra, M., Plaat, B., Nolte, I. M., Diepstra, A., Visser, L., Kok, K. & van den Berg, A., Jun-2017, In : The American Journal of Pathology. 187, 6, p. 1343-1355 13 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  5. Long Noncoding RNA Expression Profiling in Normal B-Cell Subsets and Hodgkin Lymphoma Reveals Hodgkin and Reed-Sternberg Cell Specific Long Noncoding RNAs

    Tayari, M. M., Winkle, M., Kortman, G., Sietzema, J., de Jong, D., Terpstra, M., Mestdagh, P., Kroese, F. G. M., Visser, L., Diepstra, A., Kok, K., van den Berg, A. & Kluiver, J., Sep-2016, In : The American Journal of Pathology. 186, 9, p. 2462-2472 11 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  6. Mutation patterns in small cell and non-small cell lung cancer patients suggest a different level of heterogeneity between primary and metastatic tumors

    Saber, A., Hiltermann, T. J. N., Kok, K., Terpstra, M. M., de Lange, K., Timens, W., Groen, H. J. M. & van den Berg, A., 4-Jan-2017, In : CARCINOGENESIS. 38, 2, p. 144-151 8 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  7. WEE1 Inhibition Enhances Anti-Apoptotic Dependency as a Result of Premature Mitotic Entry and DNA Damage

    de Jong, M. R. W., Langendonk, M., Reitsma, B., Herbers, P., Nijland, M., Huls, G., van den Berg, A., Ammatuna, E., Visser, L. & van Meerten, T., 7-Nov-2019, In : Cancers. 11, 11, 14 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  8. Primary and acquired resistance mechanisms to immune checkpoint inhibition in Hodgkin lymphoma

    Veldman, J., Visser, L., Berg, A. V. D. & Diepstra, A., 11-Nov-2019, In : CANCER TREATMENT REVIEWS. 82, 9 p., 101931.

    Research output: Contribution to journalReview articleAcademicpeer-review

  9. The microenvironment of classical Hodgkin lymphoma: heterogeneity by Epstein-Barr virus presence and location within the tumor

    Wu, R., Sattarzadeh, A., Rutgers, B., Diepstra, A., van den Berg, A. & Visser, L., 6-May-2016, In : Blood cancer journal. 6, 3 p., e417.

    Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

  10. CD58 mutations are common in Hodgkin lymphoma cell lines and loss of CD58 expression in tumor cells occurs in Hodgkin lymphoma patients who relapse

    Abdul Razak, F. R., Diepstra, A., Visser, L. & Berg, van den, A., Sep-2016, In : GENES AND IMMUNITY. 17, 6, p. 363-366 4 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  11. Current Smoking is Associated with Decreased Expression of miR-335-5p in Parenchymal Lung Fibroblasts

    Ong, J., van den Berg, A., Faiz, A., Boudewijn, I. M., Timens, W., Vermeulen, C. J., Oliver, B. G., Kok, K., Terpstra, M. M., van den Berge, M., Brandsma, C-A. & Kluiver, J., 2-Oct-2019, In : International Journal of Molecular Sciences. 20, 20, 14 p., 5176.

    Research output: Contribution to journalArticleAcademicpeer-review

  12. The mutational landscape of Hodgkin lymphoma cell lines determined by whole-exome sequencing

    Liu, Y., Abdul Razak, F. R., Terpstra, M., Chan, F. C., Saber, A., Nijland, M., van Imhoff, G., Visser, L., Gascoyne, R., Steidl, C., Kluiver, J., Diepstra, A., Kok, K. & van den Berg, A., Nov-2014, In : Leukemia. 28, 11, p. 2248-2251 5 p.

    Research output: Contribution to journalLetterAcademicpeer-review

View all (259) »

Activities
  1. Masters of the Genome: Unmasking the ‘genome bastards’ of lymphoma

    Anke Berg, van den (Invited speaker)
    7-Oct-2019

    Activity: Talk or presentationAcademic

  2. Unmask: Help to optimize precision medicine

    Anke Berg, van den (Invited speaker)
    7-Oct-2019

    Activity: Talk or presentationAcademic

  3. 3rd International Conference on the long and the short of non-coding RNAs

    Anke Berg, van den (Participant)
    18-Jun-201923-Jun-2019

    Activity: Participating in or organising an eventParticipation in conferenceAcademic

View all (22) »

Press / Media
  1. College

    Anke Berg, van den

    27/03/2018

    1 Media contribution

    Press/Media: Public Engagement ActivitiesPopular

View all (1) »

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