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Publications

CDK4 is co-amplified with either TP53 promoter gene fusions or MDM2 through distinct mechanisms in osteosarcoma

Centrosome amplification primes ovarian cancer cells for apoptosis and potentiates the response to chemotherapy

Characterizing chromosomal instability-driven cancer evolution and cell fitness at a glance

Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression

Chronic spindle assembly checkpoint activation causes myelosuppression and gastrointestinal atrophy

Disruption of the TP53 locus in osteosarcoma leads to TP53 promoter gene fusions and restoration of parts of the TP53 signalling pathway

Drug-resilient cancer cell phenotype is acquired via polyploidization associated with early stress response coupled to HIF-2α transcriptional regulation

Early evolutionary branching across spatial domains predisposes to clonal replacement under chemotherapy in neuroblastoma

Extra centrosomes delay DNA damage-driven tumorigenesis

Genomic instability as a driver and suppressor of anti-tumor immunity

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Press/media

Prins Bernhard en BN'ers halen 300.000 op voor lymfeklierkanker

Prins Bernhard en BN'ers halen 300.000 op voor lymfeklierkanker

Protein Associated With Neurodegenerative Diseases Found To Be Linked to Childhood Brain Cancer

Scientists discover that a protein associated with neurodegenerative diseases is also linked to childhood brain cancer

Vier onderzoekers Rijksuniversiteit en UMC Groningen slepen miljoenensubsidie binnen

Drie UMCG-onderzoeken krijgen subsidie van KWF

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