prof. dr. B.N. Melgert
Barbro Melgert studied Pharmacy at the University of Groningen, the Netherlands and graduated as Doctor of Pharmacy in 1994 (Cum Laude). She continued with research into liver fibrosis and the use of macrophage-specific drugs to intervene with this disease at the Department of Pharmacokinetics and Drug Delivery of that same university. In 2000 she successfully defended her PhD thesis called “Aiming at the cirrhotic liver: drug targeting in practice”. She moved to the Department of Pathology of the University Medical Center Groningen (UMCG) for a postdoctoral position investigating the effects of smoking, and later the effects of gender, on the development of asthma. The sex differences in immunological responses caught her attention and she continued working on this topic at the Department of Pulmonary, Allergy and Critical Care Medicine from the University of Pittsburgh, USA from 2005-2007. Late 2006 she was awarded a Young Investigator Grant by the Dutch Asthma Foundation which enabled her to continue her work on sex differences in asthma at the Department of Pathology of the UMCG. During these studies she rediscovered her interest in macrophages, but this time in the context of sex differences and lung diseases. She is currently working as an associate professor at the Department of Pharmacokinetics, Toxicology and Targeting of the University of Groningen, the Netherlands, studying macrophage behavior in lung diseases and their potential as therapeutic target.
1995 – 2000 Ph.D., Dept. of Pharmacokinetics and Drug Targeting, University of Groningen, NL
1992 – 1994 Pharmacist license, University of Groningen, NL
1986 – 1992 M.Sc., Pharmacy/Biochemistry, University of Groningen, NL (cum laude, top 5%)
2009 – 2010 Div. of Medical Biology, University Medical Center Groningen, NL
2007 – 2009 Dept. of Pathology, University Medical Center Groningen, NL
2005 – 2007 Div. of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, USA
2001 – 2005 Dept. of Pathology, University Medical Center Groningen, NL
2000 – 2001 Biomade Foundation, Groningen, NL
2015 – present Associate Professor, Dept. of Pharmacokinetics, Toxicology and Targeting, University of Groningen, NL
2010 – 2015 Assistant Professor, Dept. of Pharmacokinetics, Toxicology and Targeting, University of Groningen, NL
1994 – 1995 Research Assistant, Dept. of Social Pharmacy and Pharmacoepidemiology, University of Groningen, NL
Ongoing Research Support (Funding ID)
2016- 2017 Grant from Roche (€120.000) for fibrosis research together with Olinga (GRIP) and Faber/Dijkstra (UMCG)
2015 - 2020 Consortium grant from the Dutch Lung Fund (€750.000) together with Lutter of AMC and Martinez of Oxford University. Coordinating PI: Barbro N. Melgert. Title: Does high baseline oxidative stress attenuate macrophage function during exacerbations of COPD and asthma?
2014 - 2018 Grant (€15.000) from the Penderfonds of the Organisation of Dutch Pulmonary Fibrosis Patients to fund the exchange of human fibrotic lung tissue between RUG/UMCG and Erasmus MC in Rotterdam. PIs: Barbro N. Melgert and Bernt van der Blink.
Completed Research Support
2011 – 2015 Start up grant (€250,000) from the Faculty of Mathematics and Natural Sciences of the University of Groningen. PI: Barbro N. Melgert. Title: The role of macrophages in the development of pulmonary fibrosis and COPD.
2011 – 2015 Research grant (€255,000) from the Netherlands Asthma Foundation. PI: Barbro N. Melgert. Title: The role of alternatively activated macrophages in the pathogenesis of asthma.
2006 – 2009 The role of sex hormones in the pathogenesis of asthma, funded by Netherlands Asthma Foundation (€200,000), PI: Barbro N. Melgert
2013 – Dutch Management Team member of EU COST action “Chemical approaches to targeting drug resistance in cancer stem cells” (CM1106)
2012 – present Participation in the EU COST action “Developmental origins of chronic lung disease” (BM1201)
|Laatst gewijzigd:||15 mei 2018 14:55|