Skip to ContentSkip to Navigation
Research Zernike (ZIAM) News Seminars

Sadia Bari: Soft X-ray spectroscopy of isolated biomolecules

When:We 07-07-2021 15:00 - 16:00

Biomolecules are the building blocks of life and it is important to understand how exactly their physical properties are responsible for their functionality and responses to stressors. A very suitable method is to study isolated biomolecules with cutting-edge mass spectrometry techniques at advanced light sources to unravel their intrinsic properties, i.e. in an environment-free and controlled chemical state. In particular, Near-Edge X-ray Absorption Mass Spectrometry (NEXAMS), which is an action-spectroscopy technique based on fragment-resolved absorption upon resonant photoexcitation of core atomic levels, has been of growing interest in recent years for investigating the spatial and electronic structure of biomolecules.

In this seminar, I will present developments in spectroscopic techniques used at large-scale photon facilities to study isolated biomolecules, and I will show the latest results from NEXAMS studies on peptides, proteins and related molecules. Not only spatial and electronic structures, but also damage processes, site-selective dissociation and orbital-dependent deexcitation pathways will be discussed