Recently, it was discovered that multiple neurodegenerative diseases such as ALS are linked to impaired nucleocytoplasmic transport, which is mediated by the nuclear pore complex (NPC). ZIAM researcher Prof.dr.ir. Patrick Onck will team up with Prof.dr.ir. Cees Dekker (Delft University of Technology) and Dr. Liesbeth Veenhoff (UMCG/ERIBA) and a leading company in drug screening (Pivot Park Screening Centre BV) to explore the molecular mechanism responsible for reduced NPC transport in neurodegenerative diseases, particularly ALS. Aim of the project is to produce major new scientific insight as well as novel targets for medication.
Research in the Onck group aims at understanding the micromechanical and functional behavior of (biological) materials based on an accurate description of the underlying (bio-)physical mechanisms. Computational techniques such as (coarse-grained) molecular dynamics and finite element methods are being used to explore fundamental processes in living cells and in smart, responsive materials.
Different from previous years but still surprising, fun, healthy, and for the whole family: join Groningen’s take on this year’s national weekend of science, organized by the University of Groningen (UG) and Hanze University of Applied Sciences...
Northern Netherlands Top Dutch Solar Racing team joins forces to prepare for solar race in Morocco.
Proverbs. Without thinking about it, we make use of them daily. But our society is constantly changing. Are these ancient wisdoms any use to us still? Young researchers from various disciplines, among whom are many members of the Young Academy...
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