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Dissertations

In the table below, you find an overview of dissertations written by PhD students from the department of Pharmaceutical Technology and Biopharmacy. Click on the link to learn more about a particular dissertation.

Year Author Title
2020 Luinstra, M. Inhalable levodopa: from laboratory to the patient
2019 Bigaeva, E. Ex vivo fibrosis research: 5 mm closer to human studies
2019 Gore, E. Integrating an ex vivo model into fibrosis research
2019 Iswandana, R. Exploring the regional characteristics of intestinal drug metabolism and fibrogenesis
2019 Putri, K.S.S. Osteoprotegerin in organ fibrosis: biomarker, actor, and target of therapy?
2019 Ruigrok, M.J.R. siRNA in precision-cut lung slices: knocking down fibrosis?
2019 Suriguga, S. Pro- and anti-fibrotic agents in liver fibrosis: perspective from an ex vivo model of liver fibrosis
2018 Bhide, Y. Towards improved and broadly protective influenza vaccines: focus on delivery systems, routes of administration and animal models
2018 Kanojia, G. Drying made easy: spray drying a promising technology for the production of stable vaccine and therapeutic protein formulations
2018 Teekamp, N. Protein delivery from polymeric matrices: from pre-formulation stabilization studies to site-specific delivery
2018 Tomar, J. Paving the way for pulmonary influenza vaccines: exploring formulations, models and site of deposition
2017 Luangmonkong, T. Exploring anti-fibrotic drugs: focusing on an ex vivo model of fibrosis
2017 Mensink, M. Solid state stabilization of proteins by sugars: why size and flexibility matter
2017 Stribos, E.G.D. Ex vivo studies of renal fibrosis: insights into mechanisms and treatment targets
2017 Visser, J.C. Orodispersible films as pharmacy preparations: let’s get flexible
2016 Grasmeijer, N. Improving protein stabilization by spray drying: formulation and process development
2016 Hoppentocht, M. Dry powder inhalation of antibiotics: a promising approach for treatment of infectious diseases
2016 Pham, B.T. Precision-cut tissue slices: a novel ex vivo model for fibrosis research
2014 Grasmeijer, F. Adhesive mixtures for inhalation: the cohesion between formulation variables, inhalation variables and dispersion performance
2014 Lexmond, A. Technology in practice: the importance of matching purpose, patient, and product in pulmonary aerosol delivery
2014 Murugappan, S. New strategies for simplifying influenza vaccination
2014 Nguyen, T. Particle–particle interactions in dry powder blending: applying theoretical concepts to real-life particles
2014 Stankovic, M. Innovative platform technologies for stabilization and controlled release of proteins from polymer depots
2014 Tonnis, W. Powder to the people: the storage stability, handling, and administration advantages of powder formulations for pulmonary vaccination
2013 Willemsz, T.A. Blending of agglomerates into powders: quantification and understanding of mixing mechanisms in dry blending
2012 Avanti, C. Innovative strategies for stabilization of therapeutic peptides in aqueous formulations
2011 de Waard, H. A novel bottom-up process to prepare drug nanocrystals: the art of the soluble
2011 Schellekens, R.C.A. Translational research into oral colon-specific drug delivery: from laboratory to clinic
2011 Srinarong, P. Improved dissolution behavior of lipophilic drugs by solid dispersions: a matter of composition
2010 Laksmana, F.L. Functional encapsulation of small particles: quantification and control of the morphology of the coating layers
2010 Saluja, V. Novel perspectives for influenza vaccine formulation and administration: L. lactis cell wall derived adjuvant, stable dry powder vaccines and mucosal vaccine delivery
2009 Westerman, E.M. Studies on antibiotic aerosols for inhalation in cystic fibrosis
2009 Zijlstra, G.S. Dry powder inhalation of biopharmaceuticals: from formulation to proof-of-concept
2008 Amorij, J-P. The development of stable influenza vaccine powder formulations for new needle-free dosage forms
2008 Wu, Y.S. Looking into tablets: characterization of pore structure in tablets using image analysis
2007 de Jonge, J.M. Reconstituted viral envelopes as delivery vehicles for nucleic acids
2007 de Vegt, O.M. Jet milling from a particle perspective: predicting particle fracture based on mechanical material properties
2007 Weda, M. Equivalence testing of inhaled drugs: the predictive value of cascade impactor results for the detection of differences in efficiency and safety of medicines for the treatment of asthma and COPD
2006 Dickhoff, B.H.J. Adhesive mixtures for powder inhalation: the effect of carrier (surface and bulk) properties, carrier payload and mixing conditions on the performance of adhesive mixtures for inhalation
2006 van Drooge, D.J. Combining the incompatible: inulin glass dispersions for fast dissolution, stabilization and formulation of lipophilic drugs
2005 Bouwman, A.M. Form, formation and deformation: the influence of material properties and process conditions on the shape of granules produced by high shear granulation
2005 de Boer, A.H. Optimisation of dry powder inhalation: the application of air classifier and laser diffraction technology for the generation and characterisation of aerosols from adhesive mixtures
2005 Steendam, R. Amylodextrin and poly(DL-lactide) oral controlled release matrix tablets: concepts for understanding their release mechanisms
2004 Eriksson, H.J.C. Analytical techniques and formulation strategies for the therapeutic protein alkaline phosphatase
2003 van Veen, B. Compaction of powder blends : effect of pores, particles and percolation on tablet strength
2002 van Sorge, A.A. Reflections on flurbiprofen eyedrops
2001 de Koning, J.P. Dry powder inhalation: technical and physiological aspects, prescribing and use
2001 Le Brun, P.P.H. Optimization of antibiotic inhalation therapy in cystic fibrosis: studies on nebulized tobramycin
2001 Ramaker, J.S. Fundamentals of the high-shear pelletisation process
2000 Hartman Kok, P.J.A. Development and description of controlled release formulations for use in powder detergents
2000 Schaafsma, S.H. Down-scaling of a fluidised bed agglomeration process
2000 Wientjes, K.J.C. Development of a glucose sensor for diabetic patients

Last modified:02 March 2021 3.55 p.m.