Publications
In the list below, you find an overview of all publications of the department of Pharmaceutical Technology and Biopharmacy. Requests for electronic versions of publications may be submitted to respective corresponding authors.
2023
van
der Kooij, R. S., Beukema, M., Huckriede,
A. L. W., Zuidema, J., Steendam, R., Frijlink, H.
W., & Hinrichs, W. L. J. (2023). A
Single Injection with Sustained-Release Microspheres and a
Prime-Boost Injection of Bovine Serum Albumin Elicit the Same IgG
Antibody Response in Mice.
Pharmaceutics, 15(2), [676]. https://doi.org/10.3390/pharmaceutics15020676
Ahmed,
A. A., Otten, A. T., Gareb, B., Huijmans,
J. E., Eissens, A. C., Rehman, A., Dijkstra,
G., Kosterink, J. G. W., Frijlink, H.
W., & Schellekens, R. C. A. (2023). Capsules with
Ileocolonic-Targeted Release of Vitamin B2, B3, and C (ColoVit)
Intended for Optimization of Gut Health: Development and Validation
of the Production Process.
Pharmaceutics, 15(5), [1354]. https://doi.org/10.3390/pharmaceutics15051354
Heida,
R., Akkerman, R., Silva, P. H. J., Lakerveld,
A., Ortiz, D., Bigogno, C., Gasbarri, M., Van Kasteren, P. B.,
Stellacci, F., Frijlink, H. W., Huckriede,
A., & Hinrichs, W. (2023).
Development of an inhalable antiviral powder formulation
against respiratory syncytial virus. Journal of
Controlled Release, 357(5), 264-273. https://doi.org/10.1016/j.jconrel.2023.03.059
Otten,
A. T., Peters, V., Barth,
I., Stevens, C. L., Bourgonje, A.
R., Frijlink, H. W., Harmsen, H. J.
M., Rehman, A., Campmans-Kuijpers, M. J.
E., & Dijkstra, G. (2023). Effects of
ileocolonic delivered vitamin B2, B3 and C
(ColoVit) or the Groningen anti-inflammatory diet on disease course
and microbiome of patients with Crohn's disease (VITA-GrAID study):
a protocol for a randomised and partially blinded trial.
BMJ Open, 13(3), [e069654]. https://doi.org/10.1136/bmjopen-2022-069654
Woerdenbag,
H. J., Olinga, P., Kok, E. A., Brugman, D. A.
P., van Ark, U. F., Ramcharan, A. S., Lebbink, P. W.,
Hoogwater, F. J. H., Knapen, D. G., de
Groot, D. J. A., & Nijkamp, M. W. (2023).
Potential, Limitations and Risks of Cannabis-Derived Products
in Cancer Treatment. Cancers,
15(7), [2119]. https://doi.org/10.3390/cancers15072119
de
Jong, I. E. M., Bodewes, S. B., van
Leeuwen, O. B., Oosterhuis, D., Lantinga,
V. A., Thorne, A. M., Lascaris,
B., van den Heuvel, M. C., Wells, R. G.,
Olinga, P., de Meijer, V. E., &
Porte, R. J. (2023). Restoration of Bile Duct Injury
of Donor Livers During Ex Situ Normothermic Machine
Perfusion. Transplantation. https://doi.org/10.1097/TP.0000000000004531
Bekhof,
A. S. M. W., van Hunsel, F. P. A. M., van de Koppel, S.,
& Woerdenbag, H. J. (2023). Safety assessment and
adverse drug reaction reporting of tea tree oil (Melaleuca
aetheroleum). Phytotherapy Research,
37(4), 1309-1318. https://doi.org/10.1002/ptr.7687
2022
van
der Kooij, R. S., Steendam, R., Frijlink, H.
W., & Hinrichs, W. L. J. (2022). An
overview of the production methods for core-shell microspheres for
parenteral controlled drug delivery. European
journal of pharmaceutics and biopharmaceutics : official journal of
Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik
e.V, 170, 24-42. https://doi.org/10.1016/j.ejpb.2021.11.007
Jansen,
E. M., Frijlink, H. W., Hinrichs, W. L.
J., & Ruigrok, M. J. R. (2022). Are
inhaled mRNA vaccines safe and effective? A review of preclinical
studies. Expert Opinion on Drug
Delivery, 19(11), 1471-1485. https://doi.org/10.1080/17425247.2022.2131767
Heida,
R., Born, P. A., Tapia-Calle,
G., Frijlink, H. W., Salvati,
A., Huckriede, A. L. W., & Hinrichs,
W. L. J. (2022). Assessing the Immunomodulatory Effect
of Size on the Uptake and Immunogenicity of Influenza- and
Hepatitis B Subunit Vaccines In Vitro.
Pharmaceuticals, 15(7), [887]. https://doi.org/10.3390/ph15070887
Nguyen,
K. T. T., Heijningen, F. F. M., Zillen, D., van
Bommel, K. J. C., van Ee, R. J., Frijlink, H.
W., & Hinrichs, W. L. J. (2022).
Formulation of a 3D Printed Biopharmaceutical: The
Development of an Alkaline Phosphatase Containing Tablet with
Ileo-Colonic Release Profile to Treat Ulcerative Colitis.
Pharmaceutics, 14(10), [2179]. https://doi.org/10.3390/pharmaceutics14102179
Tian,
Y., Lee, J., van der Maaden, K., Bhide,
Y., de Vries-Idema, J. J., Akkerman,
R., O'Mahony, C., Jiskoot, W., Frijlink, H.
W., Huckriede, A. L. W., Hinrichs, W. L.
J., Bouwstra, J. A., & Beukema, M. (2022).
Intradermal Administration of Influenza Vaccine with
Trehalose and Pullulan-Based Dissolving Microneedle Arrays.
Journal of Pharmaceutical Sciences. https://doi.org/10.1016/j.xphs.2022.01.033
Woerdenbag,
H. J., Visser, J. C., Leferink Op Reinink, M.
P. A. M., van Orsoy, R. R., Eissens, A. C.,
Hagedoorn, P., Dijkstra, H., Allersma, D. P., Ng, S. W.,
Smeets, O. S. N. M., & Frijlink, H. W. (2022).
Performance of Tablet Splitters, Crushers, and Grinders in
Relation to Personalised Medication with Tablets.
Pharmaceutics, 14(2), [320]. https://doi.org/10.3390/pharmaceutics14020320
Ruigrok,
M. J. R., Roest, M. A. P., Frijlink, H.
W., Olinga, P., Hinrichs, W. L.
J., & Melgert, B. N. (2022). RANKL
confers protection against cell death in precision-cut lung
slices. Frontiers in Physiology,
13, [1029697]. https://doi.org/10.3389/fphys.2022.1029697
de
Reus, Y. A., Hagedoorn, P., Sturkenboom,
M. G. G., Grasmeijer, F., Bolhuis, M.
S., Sibum, I., Kerstjens, H. A. M.,
Frijlink, H. W., & Akkerman, O. W. (2022).
Tolerability and pharmacokinetic evaluation of inhaled dry
powder hydroxychloroquine in healthy volunteers.
PLoS ONE, 17(8), [e0272034]. https://doi.org/10.1371/journal.pone.0272034
Li,
M., de Meijer, V., Olinga,
P., Nagelkerke, A., & Geng, Y.
(2022). Development of an ex vivo model for non-alcoholic
fatty liver disease using precision-cut liver slices.
Journal of Hepatology, 77,
S711-S711.
Suriguga,
S., Li, M., Luangmonkong, T., Boersema, M., de
Jong, K. P., Oosterhuis, D., Gorter, A.
R., Beljaars, L., & Olinga, P.
(2022). Distinct responses between healthy and cirrhotic
human livers upon lipopolysaccharide challenge: possible
implications for acute-on-chronic liver failure.
American journal of physiology. Gastrointestinal and
liver physiology, 323(2), G114-G125. https://doi.org/10.1152/ajpgi.00243.2021
Luo,
K., Geng, Y., de Meijer, V.,
Oosterhuis, D., & Olinga, P. (2022).
Evaluation of the antifibrotic effects of naringenin, asiatic
acid and icariin by using precision-cut liver slices of mouse and
human. Journal of Hepatology,
77, S484-S484.
van
Furth, L. A., Leuvenink, H. G. D., Seras,
L., Graaf, I. A. M. D., Olinga, P.,
& Leeuwen, L. L. V. (2022). Exploring Porcine
Precision-Cut Kidney Slices as a Model for Transplant-Related
Ischemia-Reperfusion Injury.
Transplantology, 3(2),
139–151. https://doi.org/10.3390/transplantology3020015
Biel,
C., Martinec, O., Sibering, B., van Summeren, K.,
Wessels, A. M. A., Touw, D. J., de Jong,
K. P., de Meijer, V. E., Faber, K.
N., Klooster, J. P. T., de Graaf, I. A.
M., & Olinga, P. (2022). Extending
the viability of human precision-cut intestinal slice model for
drug metabolism studies. Archives of
toxicology. https://doi.org/10.1007/s00204-022-03295-1
Karsten,
R. E. H., Krijnen, N. J. W., Maho, W., Permentier,
H., Verpoorte, E., & Olinga,
P. (2022). Mouse precision-cut liver slices as an
ex vivo model to study drug-induced cholestasis.
Archives of toxicology, 96(9),
2523-2543. https://doi.org/10.1007/s00204-022-03321-2
Adhyatmika,
A., Putri, K. S. S., Gore, E., Mangnus, K. A., Reker-Smit,
C., Schuppan, D., Beljaars, L., Olinga,
P., & Melgert, B. N. (2022).
Osteoprotegerin Expression in Liver is Induced by IL13
through TGFβ. Cellular physiology and
biochemistry, 56(1), 28-38. https://doi.org/10.33594/000000492
van
Leeuwen, L., Leuvenink, H. G. D., Olinga,
P., & Ruigrok, M. (2022). Shifting
Paradigms for Suppressing Fibrosis in Kidney Transplants:
Supplementing Perfusion Solutions With Anti-fibrotic Drugs.
Frontiers in Medicine, 8, [806774].
https://doi.org/10.3389/fmed.2021.806774
Puerta
Cavanzo, N., Riesmeijer, S. A.,
Holt-Kedde, I. L., Werker, P. M. N.,
Piersma, B., Olinga, P., & Bank, R.
A. (2022). Verteporfin ameliorates fibrotic aspects of
Dupuytren's disease nodular fibroblasts irrespective the activation
state of the cells. Scientific
Reports, 12(1), [13940]. https://doi.org/10.1038/s41598-022-18116-9
van
Hunsel, F. P. A. M., van der Kooi, D., van de Koppel, S., Kroes, B.
H., & Woerdenbag, H. J. (2022). Analysis of
Reports on Adverse Drug Reactions Related to Herbal Medicinal
Products and Herbal Supplements in the Netherlands Received by the
National Pharmacovigilance Centre Lareb. Drug
Safety, 45(6), 651-661. https://doi.org/10.1007/s40264-022-01180-5
Borgonje,
P. E., Wibier, L., Noordman, P., Woerdenbag, H.
J., & Gareb, B. (2022). The
Development and Implementation of Airflow Visualization Studies
("Smoke" Studies) as a Training Tool in Aseptic Hospital
Compounding Facilities. Pharmacy (Basel,
Switzerland), 10(5), [101]. https://doi.org/10.3390/pharmacy10050101
2021
Heida,
R., Hinrichs, W. L. J., & Frijlink,
H. W. (2022). Inhaled vaccine delivery in the combat
against respiratory viruses: A 2021 overview of recent developments
and implications for COVID-19. Expert review of
vaccines, 21(7), 957-974. https://doi.org/10.1080/14760584.2021.1903878
Larmené-Beld,
K., Wijnsma, R., Kuiper, A., van Berkel, S., Robben, H.,
Taxis, K., & Frijlink, H. (2022).
Science- and risk-based strategy to qualify prefillable
autoclavable syringes as primary packaging material.
European Journal of Hospital Pharmacy: Science and
Practice, 29(5), 248-254. https://doi.org/10.1136/ejhpharm-2020-002333
Broesder,
A., Bircan, S. Y., De Waard, A. B., Eissens, A.
C., Frijlink, H. W., & Hinrichs, W.
L. J. (2021). Formulation and in vitro evaluation of
pellets containing sulfasalazine and caffeine to verify
ileo-colonic drug delivery.
Pharmaceutics, 13(12), [1985]. https://doi.org/10.3390/pharmaceutics13121985
Ruigrok,
M. J. R., Frijlink, H. W., Melgert, B.
N., Olinga, P., & Hinrichs, W. L.
J. (2021). Gene therapy strategies for idiopathic
pulmonary fibrosis: recent advances, current challenges, and future
directions. Molecular Therapy - Methods &
Clinical Development, 20, 483-496. https://doi.org/10.1016/j.omtm.2021.01.003
Broesder,
A., Berends, J. M. E., Scheepers, S. M.,
Nguyen, D. N., Frijlink, H. W., & Hinrichs,
W. L. J. (2021). Ileo-Colon Targeting of the Poorly
Water-Soluble Drug Celecoxib Using a pH-Dependent Coating in
Combination with Self-Emulsifying Drug Delivery or Solid Dispersion
Systems. Pharmaceutics,
13(5). https://doi.org/10.3390/pharmaceutics13050731
Gareb,
B., Beugeling, M., Posthumus, S., Otten,
A. T., Dijkstra, G., Kosterink, J. G.
W., & Frijlink, H. W. (2021).
Infliximab formulation strategy for a stable ileo-colonic
targeted oral dosage form intended for the topical treatment of
inflammatory bowel disease. Journal of drug
delivery science and technology, 64, [102552].
https://doi.org/10.1016/j.jddst.2021.102552
van
der Kooij, R. S., Steendam, R., Zuidema, J., Frijlink,
H. W., & Hinrichs, W. L. J. (2021).
Microfluidic Production of Polymeric Core-Shell Microspheres
for the Delayed Pulsatile Release of Bovine Serum Albumin as a
Model Antigen. Pharmaceutics,
13(11), [1854]. https://doi.org/10.3390/pharmaceutics13111854
Zillen,
D., Beugeling, M., Hinrichs, W. L.
J., Frijlink, H. W., & Grasmeijer,
F. (2021). Natural and bioinspired excipients for dry
powder inhalation formulations. Current Opinion in
Colloid and Interface Science, 56, [101497].
https://doi.org/10.1016/j.cocis.2021.101497
Ruigrok,
M. J. R., El Amasi, K. E. M., Leeming, D. J., Sand, J. M.
B., Frijlink, H. W., Hinrichs, W. L.
J., & Olinga, P. (2021). Silencing
Heat Shock Protein 47 (HSP47) in Fibrogenic Precision-Cut Lung
Slices: A Surprising Lack of Effects on Fibrogenesis?
Frontiers in Medicine, 8, [607962].
https://doi.org/10.3389/fmed.2021.607962
Sahal,
G., Woerdenbag, H. J., Hinrichs, W. L.
J., Visser, A., van der Mei, H.
C., & Bilkay, I. S. (2021). Candida Biofilm
Formation Assay on Essential Oil Coated Silicone Rubber.
Bio-Protocol, 11(5), [3941]. https://doi.org/10.21769/BioProtoc.3941
Setyaningsih,
D., Santoso, Y. A., Hartini, Y. S., Murti, Y. B., Hinrichs,
W. L. J., & Patramurti, C. (2021). Isocratic
high-performance liquid chromatography (HPLC) for simultaneous
quantification of curcumin and piperine in a microparticle
formulation containing Curcuma longa and Piper nigrum.
Heliyon, 7(3), [e06541]. https://doi.org/10.1016/j.heliyon.2021.e06541
Chakraborty,
P., Oosterhuis, D., Bonsignore, R., Casini,
A., Olinga, P., & Scheffers, D-J.
(2021). An organogold compound as potential antimicrobial
agent against drug resistant bacteria: Initial mechanistic
insights. ChemMedChem,
16(19), 3060-3070. https://doi.org/10.1002/cmdc.202100342
van
Praagh, J. B., de Wit, J. G., Olinga,
P., de Haan, J. J., Nagengast, W.
B., Fehrmann, R. S. N., & Havenga,
K. (2021). Colorectal anastomotic leak: Transcriptomic
profile analysis. British Journal of
Surgery, 108(3), 326-333. https://doi.org/10.1093/bjs/znaa066
Geng,
Y., Buist-Homan, M., Olinga,
P., Blokzijl, H., & Moshage,
H. (2021). Conditioned medium of hepatic stellate
cells induces a pro-inflammatory phenotype in kupffer cells via the
release of extracellular vesicles.
Hepatology, 74, 808A-809A.
Mutsaers,
H. A. M., Nørregaard, R., & Olinga, P.
(2021). Editorial: Organ Fibrosis: Pathogenesis, Biomarkers
and Therapeutic Targets. Frontiers in
Medicine, 8, [793507]. https://doi.org/10.3389/fmed.2021.793507
Pasmans,
K., Adriaens, M. E., Olinga, P., Langen, R., Rensen,
S. S., Schaap, F. G., Olde Damink, S. W. M., Caiment, F., van Loon,
L. J. C., Blaak, E. E., & Meex, R. C. R. (2021). Hepatic
Steatosis Contributes to the Development of Muscle Atrophy via
Inter-Organ Crosstalk. Frontiers in
endocrinology, 12, 733625. https://doi.org/10.3389/fendo.2021.733625
Li,
M., Oosterhuis, D., De Meijer, V.
E., Olinga, P., & Geng, Y.
(2021). High saccharides, fatty acids and insulin promote a
fibrogenic phenotype of healthy, but not nash, human precision-cut
liver slices. Hepatology, 74,
1069A-1069A.
Geng,
Y., Oosterhuis, D., De Meijer, V.
E., & Olinga, P. (2021). Lipids
inhibit the progression of fibrosis in human nash precision-cut
liver slices and human hepatic stellate cells.
Hepatology, 74, 1077A-1077A.
Jensen,
C. G., Jensen, M. S., Tingskov, S. J., Olinga, P.,
Nørregaard, R., & Mutsaers, H. A. M. (2021).
Local inhibition of indoleamine 2, 3-dioxygenase mitigates
renal fibrosis. Biomedicines,
9(8), [856]. https://doi.org/10.3390/biomedicines9080856
Puerta
Cavanzo, N., Bigaeva, E., Boersema, M.,
Olinga, P., & Bank, R. A. (2021).
Macromolecular Crowding as a Tool to Screen Anti-fibrotic
Drugs: The Scar-in-a-Jar System Revisited.
Frontiers in Medicine, 7, [615774].
https://doi.org/10.3389/fmed.2020.615774
Bartucci,
R., van der Meer, A. Z., Boersma, Y. L., Olinga,
P., & Salvati, A. (2021).
Nanoparticle-induced inflammation and fibrosis in ex vivo
murine precision-cut liver slices and effects of nanoparticle
exposure conditions. Archives of
toxicology, 95, 1267–1285. https://doi.org/10.1007/s00204-021-02992-7
Martinec,
O., Biel, C., de Graaf, I. A. M.,
Huliciak, M., de Jong, K. P., Staud, F., Cecka,
F., Olinga, P., Vokral, I., & Cerveny, L. (2021).
Rifampicin Induces Gene, Protein, and Activity of
P-Glycoprotein (ABCB1) in Human Precision-Cut Intestinal
Slices. Frontiers in Pharmacology,
12, [684156]. https://doi.org/10.3389/fphar.2021.684156
van
Furth, L., Maassen, H., Venema,
L., & Olinga, P. (2021). The effect
of the ketogenic diet on mitochondrial function in porcine
precision-cut kidney slices. Transplant
International, 34(S1), 273-274.
Prins,
G. H., Rios-Morales, M., Gerding, A., Reijngoud,
D-J., Olinga, P., & Bakker, B.
M. (2021). The Effects of Butyrate on Induced
Metabolic-Associated Fatty Liver Disease in Precision-Cut Liver
Slices. Nutrients, 13(12),
[4203]. https://doi.org/10.3390/nu13124203
Henstra,
C., van Praagh, J., Olinga, P., &
Nagelkerke, A. (2021). The gastrointestinal microbiota
in colorectal cancer cell migration and invasion.
Clinical & Experimental Metastasis,
38, 495–510. https://doi.org/10.1007/s10585-021-10130-x
Majorova,
D., Atkins, E., Martineau, H., Vokral, I., Oosterhuis,
D., Olinga, P., Wren, B., Cuccui, J., &
Werling, D. (2021). Use of Precision-Cut Tissue Slices as a
Translational Model to Study Host-Pathogen Interaction.
Frontiers in Veterinary Science, 8,
[686088]. https://doi.org/10.3389/fvets.2021.686088
Herawati,
F., Yulia, R., Arifin, B., Frasetyo, I.,
Setiasih, Woerdenbag, H. J., Avanti, C., &
Andrajati, R. (2021). Educational Video Improves Knowledge
about Outpatients' Usage of Antibiotics in Two Public Hospitals in
Indonesia. Antibiotics ,
10(5), [606]. https://doi.org/10.3390/antibiotics10050606
Zulzaga,
Z., Myagmarsuren, E., Woerdenbag, H. J., &
van Puijenbroek, E. P. (2021). Legislation and current
developments in adverse drug reaction reporting in Mongolia: how
far are we? Journal of Pharmaceutical Policy and
Practice, 14(1), [15]. https://doi.org/10.1186/s40545-021-00298-8
2020
Heida,
R., Bhide, Y. C., Gasbarri, M., Kocabiyik,
Ö., Stellacci, F., Huckriede, A. L. W.,
Hinrichs, W. L. J., & Frijlink, H. W.
(2021). Advances in the development of entry inhibitors for
sialic-acid-targeting viruses. Drug Discovery
Today, 26(1), 122-137. https://doi.org/10.1016/j.drudis.2020.10.009
Akkerman-Nijland,
A. M., Akkerman, O. W., Grasmeijer,
F., Hagedoorn, P., Frijlink, H.
W., Rottier, B. L., Koppelman, G.
H., & Touw, D. J. (2021). The
pharmacokinetics of antibiotics in cystic fibrosis.
Expert Opinion on Drug Metabolism &
Toxicology, 17(1), 53-68. https://doi.org/10.1080/17425255.2021.1836157
Hagedoorn,
P., Bawary, W., Frijlink, H. W., &
Grasmeijer, F. (2020). A comparative analysis of
changes in pMDI drug dose delivery before and after detergent
coating using five antistatic valved holding chambers.
Journal of Allergy and Clinical Immunology: In
Practice, 8(3), 1124-1125.e4. https://doi.org/10.1016/j.jaip.2019.09.021
Sibum,
I., Hagedoorn, P., Botterman, C. O.,
Frijlink, H. W., & Grasmeijer, F. (2020).
Automated Filling Equipment Allows Increase in the Maximum
Dose to Be Filled in the Cyclops(R)High Dose Dry Powder Inhalation
Device While Maintaining Dispersibility.
Pharmaceutics, 12(7), 1-14. [645].
https://doi.org/10.3390/pharmaceutics12070645
Akkerman-Nijland,
A. M., Grasmeijer, F., Kerstjens, H. A.
M., Frijlink, H. W., van der Vaart,
H., Vonk, J. M., Hagedoorn,
P., Rottier, B. L., Koppelman, G.
H., & Akkerman, O. W. (2020).
Colistin dry powder inhalation with the Twincer (TM): An
effective and more patient friendly alternative to
nebulization. PLoS ONE,
15(9), [e0239658]. https://doi.org/10.1371/journal.pone.0239658
Hagedoorn,
P., Grasmeijer, F., Bawari, W., Frijlink,
H. W., & Grasmeijer, F. (2020).
Comparing five antistatic valved holding chambers: How
antistatic are they really? European Respiratory
Journal, 56. https://doi.org/10.1183/13993003.congress-2020.3177
Gareb,
B., Dijkstra, G., Kosterink, J. G.
W., & Frijlink, H. W. (2020). De
ontwikkeling van budesonidetabletten met nulde-orde-afgifte voor de
behandeling van ileo-colonische inflammatoire darmziekten en
vergelijking met huidige, commerciële preparaten.
Pharmaceutisch Weekblad, 155(6),
29-36. https://www.npfo.nl/artikel/de-ontwikkeling-van-budesonidetabletten-met-nulde-orde-afgifte-voor-de-behandeling-van-ileo
Tian,
Y., Bhide, Y. C., Woerdenbag, H.
J., Huckriede, A. L. W., Frijlink, H.
W., Hinrichs, W. L. J., & Visser, J.
C. (2020). Development of an Orodispersible Film
Containing Stabilized Influenza Vaccine.
Pharmaceutics, 12(3), [245]. https://doi.org/10.3390/pharmaceutics12030245
Weerts,
Z. Z. R. M., Masclee, A. A. M., Witteman, B. J. M., Clemens, C. H.
M., Winkens, B., Brouwers, J. R. B. J., Frijlink, H.
W., Muris, J. W. M., De Wit, N. J., Essers, B. A. B., Tack,
J., Snijkers, J. T. W., Bours, A. M. H., de Ruiter-van der Ploeg,
A. S., Jonkers, D. M. A. E., & Keszthelyi, D. (2020).
Efficacy and Safety of Peppermint Oil in a Randomized,
Double-Blind Trial of Patients With Irritable Bowel
Syndrome. Gastroenterology,
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