The European Research Council (ERC) awards ERC Advanced Grants to established top scientists for their outstanding scientific research. They receive up to 2.5 million euros over a period of five years as funding for their basic research. Today, the ERC announced in Brussels that Kathrin Thedieck from the University of Innsbruck, Austria, will receive this prestigious award.
The protein mTOR controls virtually all metabolic processes in cells and organisms and is a key therapeutic target in aging-associated diseases such as cancer and neurodegenerative disorders. mTOR is at the center of a complex cellular signaling and metabolic network. In response to growth factors, nutrients, energy, and stress, mTOR promotes metabolic processes that control cell growth and differentiation. But how are specific metabolic responses to different metabolic signals mediated? Kathrin Thedieck’s research centers upon this question. Recently, she and her team observed that proteins from so-called stress granules interact with mTOR beyond stress and control mTOR-dependent metabolic processes. With her BEYOND STRESS project, she is investigating this phenomenon and its significance for the functions of healthy cells and in tumors.
Kathrin Thedieck is Professor and Head of the Institute of Biochemistry at the University of Innsbruck. She is Honorary Professor at the University of Groningen (The Netherlands) and faculty member at the University of Oldenburg (Germany). Her research group investigates the regulation of metabolism by complex signaling networks to study fundamental cellular mechanisms of metabolic signal transduction by experiments and systems modeling. Kathrin Thedieck has received many awards and coordinates the European breast cancer consortium MESI-STRAT.
Read more at the website from the University of Innsbruck : https://www.uibk.ac.at/en/newsroom/2022/innsbruck-researchers-awarded-three-erc-advanced-grants/
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