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Research Department of Genetics Staff
University Medical Center Groningen

Monique van der Wijst, PhD

Associate Professor in Single-cell Functional Biology
Dr. Monique van der Wijst
Dr. Monique van der Wijst

BSc in Biomedical Sciences from the Radboud University Nijmegen, 2010
MSc in Oncology from the VU University Amsterdam, 2012
PhD thesis: Reactive oxygen species in health and disease: Finding the right balance
University of Groningen, 2016 (cum laude)


See my publications in Google Scholar or at Pubmed

Keywords: Single cell omics, Genetics, Epigenetics, Mitochondria, Within-donor cell-to-cell variation

Research interests

Monique van der Wijst is a molecular biologist who applies novel single-cell technologies to study the interplay between genetic and environmental factors in immune-mediated diseases. In addition, in 2019 and 2023 she received NWO Veni and Vidi grants, respectively, to pursue how (non-genetic) cell-to-cell variability impacts gene expression, its regulation, and the immune response. Moreover, in 2018, she set up the sc-eQTLGen consortium (, in which, together with a network of 28 participating groups, pipelines have been set up to conduct large-scale single-cell analyses in population genetic datasets. With all these efforts combined, she aims to gain a personalized understanding of gene regulation that can improve precision medicine in the future.

Research grants/prizes

  • 2023 Aspasia grant (€40,000), Netherlands Organization for Scientific Reserach, NWO
  • 2023 VIDI Award (€800,000), Netherlands Organization for Scientific Reserach, NWO
  • 2020–2022 VENI Fellowship (€250,000), Netherlands Organization for Scientific Research, NWO
  • 2019 Simonsfonds travel grant (€1,200), to visit the lab of Dr. Jimmie Ye at the UCSF in San Francisco, USA
  • 2018 Medium investment grant (€115,712), Netherlands Organization for Scientific Research, NWO
  • 2015 Jan Kornelis de Cock Stichting research grant (€4,500 )
  • 2011 KWF internship grant (€1,200 )
  • 2011 Dutch Stomach, Liver, Intestine Society internship grant (€1,800) to visit the lab of Prof. Joan Heath at the Ludwig Institute for Cancer Research in Melbourne, Australia.
  • 2011 VU Fondsendesk grant (€300), VU University Amsterdam.
  • 2011 VUMC Faculty grant (€380), VU Medical Center, Amsterdam.

Invited/oral presentations (last five years)

  • Gene Forum, Tartu, Estonia 2023 (invited speaker)
  • ARVO Annual Meeting, New Orleans, Louisiana, USA 2023 (invited speaker)
  • Translational Immunology Groningen – TRIGR, Groningen, the Netherlands 2022 (keynote speaker)
  • Single cell Network Leiden symposium, Rotterdam, Leiden, the Netherlands 2019, 2021 (invited speaker)
  • Oncode Postdoc retreat, Lunteren, the Netherlands 2021 (oral presentation)
  • 13th Annual international conference on systems biology of human disease – SBHD, Berlin, Germany, 2021 (invited speaker)

Publications (last five years)

*, **, *** Equal contributions

Last modified:07 May 2024 10.56 a.m.