Skip to ContentSkip to Navigation
About us Latest news News News articles

Kinome profiling - methods and applications

26 April 2010

Promotie: dhr. K.B. Parikh, 14.45 uur, Academiegebouw, Broerstraat 5, Groningen

Proefschrift: Kinome profiling - methods and applications

Promotor(s): prof.dr. M.P. Peppelenbosch, prof.dr. S. Poppema

Faculteit: Medische Wetenschappen

Contact: via de persvoorlichters van het UMCG, tel. 050-361 2200, e-mail: voorlichting bvl.umcg.nl

Kinome profiling - methods and applications

Kinomics is a recent technology for the global analysis of signal transduction pathways in cells. The thesis describes this technology in detail and demonstrates its successful application to cells and tissue systems.

Kinome profiling is used to define a consensus substrate for two highly homologous kinases with very different roles in the physiology of the cell, c-Raf and MAP3K8. The results show that, although the consensus sequences for these two kinases are similar, there are certainly differences that could explain differences in biological action.

Last modified:13 March 2020 01.16 a.m.
printView this page in: Nederlands

More news

  • 01 September 2021

    Sense or nonsense? Young researchers are putting twenty proverbs to the test

    Proverbs. Without thinking about it, we make use of them daily. But our society is constantly changing. Are these ancient wisdoms any use to us still? Young researchers from various disciplines, among whom are many members of the Young Academy...

  • 15 June 2021

    From ‘closed’ science to Open Science

    Vera Heininga is the Open Science coordinator and future programme leader of the upcoming Open Science programme of the University of Groningen. Together with her colleagues, she created the Open Science Community Groningen (OSCG). She explains...

  • 17 May 2021

    ‘Encouraging young people, that’s my most important job’

    Four and a half years ago, he received the Nobel Prize. During the award ceremony in Stockholm, Ben Feringa made a resolution: I will put science on the map. His mission is being given a new boost with the establishment of the Ben Feringa Fund,...