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Research projects Health and Food

Below an overview of all research within the flagship Health and Food.

2024

Ferreira, V. R., Metting, E., Schauble, J., Seddighi, H., Beumeler, L., & Gallo, V. (2024). Correction to: eHealth tools to assess the neurological function for research, in absence of the neurologist – a systematic review, part I (software) (Journal of Neurology, (2024), 271, 1, (211-230), 10.1007/s00415-023-12012-6). Journal of Neurology, 271(11), 7376. https://doi.org/10.1007/s00415-024-12558-z
Doornenbal, B. M., van Zutphen, T., Beumeler, L. F. E., Vos, R. C., Derks, M., Haisma, H., van den Akker-van Marle, M. E., & Kiefte-de Jong, J. C. (2024). Development and validation of a Context-sensitive Positive Health Questionnaire (CPHQ): A factor analysis and multivariate regression study. Journal of patient-reported outcomes, 8(1), Article 44. https://doi.org/10.1186/s41687-024-00718-8
Galvis-Pedraza, M., Beumeler, L. F. E., van der Slikke, E. C., Boerma, E. C., & van Zutphen, T. (2024). Mitochondrial DNA in plasma and long-term physical recovery of critically ill patients: an observational study. Intensive Care Medicine Experimental, 12(1), Article 99. https://doi.org/10.1186/s40635-024-00690-z
de Vries, H. D. (2024). Bile acid metabolism in health and disease: Development, characterization and application of mouse models for (neonatal) cholestatic liver disease. [Thesis fully internal (DIV), University of Groningen]. University of Groningen. https://doi.org/10.33612/diss.1017622333
de Vries, H. D., Eijgenraam, T. R., Bloks, V. W., Mulder, N. L., van Zutphen, T., Silljé, H. H. W., Kuipers, F., & de Boer, J. F. (2024). Elevated plasma bile acids coincide with cardiac stress and inflammation in young Cyp2c70−/− mice. Pediatric Research. Advance online publication. https://doi.org/10.1038/s41390-024-03596-4
Nijenhuis, B., van Wensen, E., Smit, M., van Zutphen, T., Zwerver, J., & Tijssen, M. A. J. (2024). Treatment of task-specific dystonia in sports: A systematic review. Clinical Parkinsonism and Related Disorders, 10, Article 100245. https://doi.org/10.1016/j.prdoa.2024.100245
Hoffman, J. T., Heuvelings, D. J. I., van Zutphen, T., Stassen, L. P. S., Kruijff, S., Boerma, E. C., Bouvy, N. D., Heeman, W. T., & Al-Taher, M. (2024). Real-time quantification of laser speckle contrast imaging during intestinal laparoscopic surgery: successful demonstration in a porcine intestinal ischemia model. Surgical Endoscopy, 38(9), 5292-5303. https://doi.org/10.1007/s00464-024-11076-3
Visser, E., Ten Brinke, A., Sizoo, D., Pepels, J. J. S., Ten Have, L., van der Wiel, E., van Zutphen, T., Kerstjens, H. A. M., & de Jong, K. (2024). Effect of dietary interventions on markers of type 2 inflammation in asthma: A systematic review. Respiratory Medicine, 221, Article 107504. https://doi.org/10.1016/j.rmed.2023.107504
Dutch Audit for Treament of Obesity Research Group, van der Laan, L., Sizoo, D., van Beek, A. P., & Emous, M. (2025). Comparable results 5 years after one anastomosis gastric bypass compared to Roux-en-Y gastric bypass: a propensity-score matched analysis. Surgery for Obesity and Related Diseases, 21(3), 263-270. https://doi.org/10.1016/j.soard.2024.09.009
van der Laan, L., Sizoo, D., de Heide, L. J. M., van Beek, A. P., & Emous, M. (2024). Fewer patients with insufficient weight loss after one anastomosis gastric bypass compared to Roux-en-Y gastric bypass after 5 years of follow-up. Clinical Obesity. Advance online publication. https://doi.org/10.1111/cob.12728
Sizoo, D. (2024). Obesity and Muscle: Measurement methods and comorbidities. [Thesis fully internal (DIV), University of Groningen]. University of Groningen. https://doi.org/10.33612/diss.992833908
Kremer, D., Sizoo, D., Bakker, S. J. L., & Beek, A. P. V. (2024). Obesity management strategies should cut fat, not muscle. International Journal of Obesity, 48, 1039–1040. https://doi.org/10.1038/s41366-024-01502-w
van der Laan, L., Sizoo, D., de Heide, L. J. M., van Beek, A. P., & Emous, M. (2024). The One Anastomosis Gastric Bypass Is a Suitable Alternative to Roux-en-Y Gastric Bypass in Patients with Body Mass Index ≥50 kg/m2: A Propensity Score-Matched Analysis. Obesity Facts. Advance online publication. https://doi.org/10.1159/000542681

2023

Ferreira, V. R., Metting, E., Schauble, J., Seddighi, H., Beumeler, L., & Gallo, V. (2024). eHealth tools to assess the neurological function for research, in absence of the neurologist: a systematic review, part I (software). Journal of Neurology, 271, 211-230. https://doi.org/10.1007/s00415-023-12012-6
Beumeler, L. (2023). I see you: unravelling pathways of recovery after critical illness. [Thesis fully internal (DIV), University of Groningen]. University of Groningen. https://doi.org/10.33612/diss.582211357
Beumeler, L., Visser, E., Buter, H., Navis, G., Boerma, C., & van Zutphen, T. (2023). Protein and energy intake in intensive care unit survivors during the first year of recovery: A descriptive cohort study. Journal of Parenteral and Enteral Nutrition, 48(1), 93-99. https://doi.org/10.1002/jpen.2572
Barth, I., Beumeler, L. F. E., Venrooij, L. N., Dijk, O. V., Buter, H., & Boerma, E. C. (2023). The effect of Protein Provision and Exercise Therapy on Patientā€Reported and Clinical Outcomes in ICU Survivors: A Systematic Review. Journal of human nutrition and dietetics, 36(5), 1727-1740. https://doi.org/10.1111/jhn.13188
van der Slikke, K., Beumeler, L., Holmqvist, M., Linder, A., Mankowski, R., & Bouma, H. (2023). Understanding Post-Sepsis Syndrome: How Can Clinicians Help? Infection and Drug Resistance, 16, 6493-6511. https://doi.org/10.2147/IDR.S390947
Palmiotti, A., de Vries, H. D., Hovingh, M. V., Koehorst, M., Mulder, N. L., Verkade, E., Veentjer, M. K., van Dijk, T. H., Bloks, V. W., Havinga, R., Verkade, H. J., de Boer, J. F., & Kuipers, F. (2023). Bile Acid Sequestration via Colesevelam Reduces Bile Acid Hydrophobicity and Improves Liver Pathology in Cyp2c70-/- Mice with a Human-like Bile Acid Composition. Biomedicines, 11(9), Article 2495. https://doi.org/10.3390/biomedicines11092495
Verkade, E., Shen, W., Hovingh, M. V., Mulder, N. L., de Bruyn, K., Koehorst, M., de Vries, H. D., Bloks, V. W., Kuipers, F., & de Boer, J. F. (2023). Gut microbiota depletion aggravates bile acid-induced liver pathology in mice with a human-like bile acid composition. Clinical Science, 137(21), 1637–1650. https://doi.org/10.1042/CS20230812
Nijenhuis, B., Tijssen, M. A. J., van Zutphen, T., van der Eb, J., Otten, E., & Elting, J. W. (2023). Inter-muscular coherence in speed skaters with skater's cramp. Parkinsonism & Related Disorders, 107, Article 105250. https://doi.org/10.1016/j.parkreldis.2022.105250
Tibben, M. I., Wensen, ERIK. VAN., Nijenhuis, B., & Zwerver, J. (2023). Is Behavioural Therapy a New Treatment Option for Task-Specific Dystonia in Athletes? A Case Series. Tremor and Other Hyperkinetic Movements, 13(1), Article 16. https://doi.org/10.5334/tohm.737
Nijenhuis, B. (2023). Is Skater’s Cramp a Task-Specific Dystonia? [Thesis fully internal (DIV), University of Groningen]. University of Groningen. https://doi.org/10.33612/diss.672430858
Nijenhuis, B., Tijssen, M. A. J., van Zutphen, T., Elting, J. W., Schalkwijk, A. H. P., Otten, E., & van der Eb, J. (2023). Muscular and kinematic features in speed skaters indicate a task-specific dystonia. Clinical Neurophysiology, 149, 113-120. https://doi.org/10.1016/j.clinph.2023.02.168
Nijenhuis, B., van Zutphen, T., Gul, P., Otten, E., & Tijssen, M. A. J. (2023). Personality in speed skaters with skater's cramp: A preliminary cross-sectional study. Journal of Psychosomatic Research, 173, Article 111440. https://doi.org/10.1016/j.jpsychores.2023.111440
Heeman, W., Calon, J., van der Bilt, A., Pierie, J. P. E. N., Pereboom, I., van Dam, G. M., & Boerma, E. C. (2023). Dye-free visualisation of intestinal perfusion using laser speckle contrast imaging in laparoscopic surgery: a prospective, observational multi-centre study. Surgical Endoscopy, 37(12), 9139-9146. https://doi.org/10.1007/s00464-023-10493-0
Visser, E. (2023). Diet and body composition in asthma: Associations with clinical outcomes and inflammatory markers. [Thesis fully internal (DIV), University of Groningen]. University of Groningen. https://doi.org/10.33612/diss.771415519
Visser, E., de Jong, K., van Zutphen, T., Kerstjens, H. A. M., & Ten Brinke, A. (2023). Dietary Inflammatory Index and clinical outcome measures in adults with moderate to severe asthma. The journal of allergy and clinical immunology. In practice, 11(12), 3680-3689.e7. https://doi.org/10.1016/j.jaip.2023.08.032
Visser, E., de Jong, K., Pepels, J. J. S., Kerstjens, H. A. M., Ten Brinke, A., & van Zutphen, T. (2023). Diet quality, food intake and incident adult-onset asthma: a Lifelines Cohort Study. European Journal of Nutrition, 62(4), 1635-1645. https://doi.org/10.1007/s00394-023-03091-2
Visser, E., Ten Have, L., Ten Brinke, A., & de Jong, K. (2023). Effect of Biologic Therapy on Total Body Composition in Severe Asthma. Annals of the American Thoracic Society, 20(12), 1825-1828. https://doi.org/10.1513/AnnalsATS.202304-321RL
Visser, E., de Jong, K., Zutphen, T. V., Kerstjens, H. A. M., & ten Brinke, A. (2023). Muscle Function in Moderate to Severe Asthma: Association With Clinical Outcomes and Inflammatory Markers. The Journal of Allergy and Clinical Immunology: In Practice, 11(5), 1439-1447. https://doi.org/10.1016/j.jaip.2022.12.043
Sizoo, D., Stam, S. P., de Heide, L. J. M., Emous, M., van Zutphen, T., van Dijk, P. R., & van Beek, A. P. (2023). The association of low muscle mass with prevalence and incidence of type 2 diabetes in different BMI classes. Diabetes Research and Clinical Practice, 195, Article 110197. https://doi.org/10.1016/j.diabres.2022.110197
McLelland, G.-L., Lopez-Osias, M., Verzijl, C. R. C., Ellenbroek, B. D., Oliveira, R. A., Boon, N. J., Dekker, M., van den Hengel, L. G., Ali, R., Janssen, H., Song, J.-Y., Krimpenfort, P., van Zutphen, T., Jonker, J. W., & Brummelkamp, T. R. (2023). Identification of an alternative triglyceride biosynthesis pathway. Nature, 621, 171–178. https://doi.org/10.1038/s41586-023-06497-4
Yang, J., van Dijk, T. H., Koehorst, M., Havinga, R., de Boer, J. F., Kuipers, F., & van Zutphen, T. (2023). Intestinal Farnesoid X Receptor Modulates Duodenal Surface Area but Does Not Control Glucose Absorption in Mice. International Journal of Molecular Sciences, 24(4), Article 4132. https://doi.org/10.3390/ijms24044132

2022

Beumeler, L., Bethlehem, C., Hoogstins - Vlagsma, T., van Zutphen, T., Buter, H., Navis, G., & Boerma, C. (2023). The prevalence of mental frailty in ICU survivors and informal caregiver strain: A 1-year retrospective study of the Frisian aftercare cohort. Journal of the intensive care society, 24(4), 356-363. https://doi.org/10.1177/17511437221139547
Ribeiro Ferreira, V., Seddighi, H., Beumeler, L., Metting, E., & Gallo, V. (2022). eHealth tools to assess neurological function: a systematic review protocol for a mapping exercise. BMJ Open, 12(9), Article e062691. https://doi.org/10.1136/bmjopen-2022-062691
Beumeler, L. F. E., van Wieren, A., Buter, H., van Zutphen, T., Navis, G. J., & Boerma, E. C. (2022). Long-term health-related quality of life, healthcare utilisation and back-to-work activities in intensive care unit survivors: Prospective confirmatory study from the Frisian aftercare cohort. PLoS ONE, 17(9), Article e0273348. https://doi.org/10.1371/journal.pone.0273348
Stellingwerf, F., Beumeler, L., Rijnhart-de Jong, H., Boerma, C., & Buter, H. (2022). The predictive value of phase angle on long-term outcome after ICU admission. Clinical Nutrition, 41(6), 1256-1259. https://doi.org/10.1016/j.clnu.2022.03.029
de Vries, H. D., Palmiotti, A., Li, R., Hovingh, M. V., Mulder, N. L., Koehorst, M., Bloks, V. W., van Zutphen, T., Kuipers, F., & de Boer, J. F. (2023). Perinatal exposure to UDCA prevents neonatal cholestasis in Cyp2c70-/- mice with human-like bile acids. Pediatric Research, 93(6), 1582–1590. https://doi.org/10.1038/s41390-022-02303-5
Yang, J., de Vries, H. D., Mayeuf-Louchart, A., Stroeve, J. H., Bloks, V. W., Koehorst, M., Duez, H., Staels, B., Kuipers, F., & van Zutphen, T. (2023). Role of bile acid receptor FXR in development and function of brown adipose tissue. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, Article 159257. https://doi.org/10.1016/j.bbalip.2022.159257
Heeman, W., Wildeboer, A. C. L., Al-Taher, M., Calon, J. E. M., Stassen, L. P. S., Diana, M., Derikx, J. P. M., van Dam, G. M., Boerma, E. C., & Bouvy, N. D. (2023). Experimental evaluation of laparoscopic laser speckle contrast imaging to visualize perfusion deficits during intestinal surgery. Surgical endoscopy and other interventional techniques, 37, 950–957. https://doi.org/10.1007/s00464-022-09536-9
Heeman, W., Vonk, J., Ntziachristos, V., Pogue, B., Dierckx, R. A., Kruijff, S., & van Dam, G. M. (2022). A guideline for clinicians performing clinical studies with fluorescence imaging. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 63(5), 640-645. https://doi.org/10.2967/jnumed.121.262975
Heeman, W. (2022). Clinical translation of laser speckle contrast imaging. [Thesis fully internal (DIV), University of Groningen]. University of Groningen. https://doi.org/10.33612/diss.256850700
Vonk, J., Voskuil, F. J., de Wit, J. G., Heeman, W. T., Nagengast, W. B., van Dam, G. M., Feijen, R. A., Korsten-Meijer, A. G. W., van der Vegt, B., & Witjes, M. J. H. (2022). Fluorescence grid analysis for the evaluation of piecemeal surgery in sinonasal inverted papilloma: a proof-of-concept study. European Journal of Nuclear Medicine and Molecular Imaging, 49, 1640–1649. https://doi.org/10.1007/s00259-021-05567-x
Feitsma, E. A., Schouw, H. M., Noltes, M. E., Heeman, W., Kelder, W., van Dam, G. M., & Kruijff, S. (2022). Heterogeneity in Utilization of Optical Imaging Guided Surgery for Identifying or Preserving the Parathyroid Glands-A Meta-Narrative Review. Life, 12(3), Article 388. https://doi.org/10.3390/life12030388
Wildeboer, A., Heeman, W., van der Bilt, A., Hoff, C., Calon, J., Boerma, E. C., Al-Taher, M., & Bouvy, N. (2022). Laparoscopic Laser Speckle Contrast Imaging Can Visualize Anastomotic Perfusion: A Demonstration in a Porcine Model. Life, 12(8), Article 1251. https://doi.org/10.3390/life12081251
Heeman, W., Maassen, H., Dijkstra, K., Calon, J., van Goor, H., Leuvenink, H., van Dam, G. M., & Boerma, E. C. (2022). Real-time, multi-spectral motion artefact correction and compensation for laser speckle contrast imaging. Scientific Reports, 12(1), Article 21718. https://doi.org/10.1038/s41598-022-26154-6
Visioli, F., Bodereau, V., van der Kamp, M., Clegg, M., Guo, J., del Castillo, M. D., Gilcrease, W., Hollywood, A., Iriondo-DeHond, A., Mills, C., Sciascia, S., van Zutphen, T., Visser, E., & Willett, W. C. (2022). Educating health care professionals on the importance of proper diets. An online course on nutrition, health, and sustainability. International journal of food sciences and nutrition, 73(8), 1091-1095. https://doi.org/10.1080/09637486.2022.2123908
Nies, V. J. M., Struik, D., Liu, S., Liu, W., Kruit, J. K., Downes, M., van Zutphen, T., Verkade, H. J., Evans, R. M., & Jonker, J. W. (2022). Autocrine FGF1 signaling promotes glucose uptake in adipocytes. Proceedings of the National Academy of Sciences of the United States of America, 119(40), Article e2122382119. https://doi.org/10.1073/pnas.2122382119
Sancar, G., Liu, S., Gasser, E., Alvarez, J. G., Moutos, C., Kim, K., van Zutphen, T., Wang, Y., Huddy, T. F., Ross, B., Dai, Y., Zepeda, D., Collins, B., Tilley, E., Kolar, M. J., Yu, R. T., Atkins, A. R., van Dijk, T. H., Saghatelian, A., ... Evans, R. M. (2022). FGF1 and insulin control lipolysis by convergent pathways. Cell Metabolism, 34(1), 171-183.E6. https://doi.org/10.1016/j.cmet.2021.12.004

2021

Li, R., Palmiotti, A., de Vries, H. D., Hovingh, M. V., Koehorst, M., Mulder, N. L., Zhang, Y., Kats, K., Bloks, V. W., Fu, J., Verkade, H. J., de Boer, J. F., & Kuipers, F. (2021). Low production of 12 alpha-hydroxylated bile acids prevents hepatic steatosis in Cyp2c70(-/-) mice by reducing fat absorption. Journal of Lipid Research, 62, Article 100134. https://doi.org/10.1016/j.jlr.2021.100134
Li, R., Palmiotti, A., de Vries, H. D., Hovingh, M. V., Koehorst, M., Mulder, N. L., Zhang, Y., Kats, K., Bloks, V. W., Fu, J., Verkade, H. J., de Boer, J. F., & Kuipers, F. (2021). Low production of 12 alpha-hydroxylated bile acids prevents hepatic steatosis in mice with a human-like bile acid pool by reducing fat absorption. Hepatology, 74(S1), 1077A-1078A.
de Vries, H., Palmiotti, A., Li, R., Hovingh, M., Mulder, N., Koehorst, M., Van Zutphen, T., Kuipers, F., & De Boer, J. F. (2021). URSODEOXYCHOLIC ACID TREATMENT OF MOTHERS DURING PREGNANCY AND SUCKLING PREVENTS NEONATAL CHOLESTASIS IN NEWBORN Cyp2c70-/- MICE WITH A HUMAN-LIKE BILE ACID POOL. Hepatology, 74, 278A-279A.
Noltes, M. E., Metman, M. J. H., Heeman, W., Rotstein, L., van Ginhoven, T. M., Vriens, M. R., Engelsman, A. F., Boerma, C. E., Brouwers, A. H., van Dam, G. M., Pasternak, J. D., & Kruijff, S. (2021). A Novel and Generic Workflow of Indocyanine Green Perfusion Assessment Integrating Standardization and Quantification Towards Clinical Implementation. Annals of Surgery, 274(6), e659-e663. https://doi.org/10.1097/SLA.0000000000004978
Heeman, W., Maassen, H., Calon, J., van Goor, H., Leuvenink, H., van Dam, G. M., & Boerma, E. C. (2021). Real-time visualization of renal microperfusion using laser speckle contrast imaging. Journal of Biomedical Optics, 26(5), 1-14. Article 056004. https://doi.org/10.1117/1.JBO.26.5.056004
Sizoo, D., de Heide, L. J. M., Emous, M., van Zutphen, T., Navis, G., & van Beek, A. P. (2021). Measuring Muscle Mass and Strength in Obesity: A Review of Various Methods. Obesity Surgery, 31(1), 384-393. https://doi.org/10.1007/s11695-020-05082-2
van den Broek, M., de Heide, L. J. M., Sips, F. L. P., Koehorst, M., van Zutphen, T., Emous, M., van Faassen, M., Groen, A. K., van Riel, N. A. W., de Boer, J. F., van Beek, A. P., & Kuipers, F. (2021). Altered bile acid kinetics contribute to postprandial hypoglycaemia after Roux-en-Y gastric bypass surgery. International Journal of Obesity, 45(3), 619-630. https://doi.org/10.1038/s41366-020-00726-w

2020

Beumeler, L. F. E., van Wieren, A., Buter, H., van Zutphen, T., Bruins, N. A., de Jager, C. M., Koopmans, M., Navis, G. J., & Boerma, C. (2020). Patient-reported physical functioning is limited in almost half of critical illness survivors 1-year after ICU-admission: A retrospective single-centre study. PLoS ONE, 15(12), Article e0243981. https://doi.org/10.1371/journal.pone.0243981
de Boer, J. F., de Vries, H. D., Palmiotti, A., Li, R., Doestzada, M., Hoogerland, J. A., Fu, J., La Rose, A. M., Westerterp, M., Mulder, N. L., Hovingh, M. V., Koehorst, M., Kloosterhuis, N. J., Wolters, J. C., Bloks, V. W., Haas, J. T., Dombrowicz, D., Staels, B., van de Sluis, B., & Kuipers, F. (2021). Cholangiopathy and biliary fibrosis in Cyp2c70-deficient mice are fully reversed by ursodeoxycholic acid. Cellular and molecular gastroenterology and hepatology, 11(4), 1045-1069. https://doi.org/10.1016/j.jcmgh.2020.12.004
Visser, E., Geleijnse, J. M., & de Roos, B. (2020). Inter-individual Variation in Cancer and Cardiometabolic Health Outcomes in Response to Coffee Consumption: a Critical Review. Molecular Nutrition & Food Research, 64(7), Article e1900479. https://doi.org/10.1002/mnfr.201900479

2019

Beumeler, L., Bruins, N., de Jager, C., Buter, H., Koopmans, M., van Zutphen, T., & Boerma, C. (2019). Long-term physical recovery after critical illness is limited. 55-55. Poster session presented at 32nd Annual Congress of the European Society of Intensive Care Medicine (ESICM LIVES 2019), Berlijn, Berlin, Germany. https://icm-experimental.springeropen.com/track/pdf/10.1186/s40635-019-0265-y
de Boer, J. F., Verkade, E., Mulder, N. L., de Vries, H. D., Huijkman, N. C., Koehorst, M., Boer, T., Wolters, J. C., Bloks, V. W., van de Sluis, B., & Kuipers, F. (2020). A human-like bile acid pool induced by deletion of hepatic Cyp2c70 modulates effects of FXR activation in mice[S]. Journal of Lipid Research, 61(3), 291-305. https://doi.org/10.1194/jlr.RA119000243
de Boer, J. F., Verkade, E., Mulder, N. L., de Vries, H. D., Huijkman, N., Koehorst, M., Boer, T., Wolters, J. C., Bloks, V. W., van de Sluis, B., & Kuipers, F. (2019). A humanized bile acid pool induced by somatic CRISPR/Cas9-mediated deletion of Cyp2c70 modulates effects of pharmacological FXR activation in mice. Journal of Hepatology, 70, E25-E26.
De Boer, J. F., de Vries, H. D., Palmiotti, A., Li, R., Mulder, N. L., Hovingh, M. V., Koehorst, M., Kloosterhuis, N. J., Bloks, V. W., van de Sluis, B., & Kuipers, F. (2019). A HUMAN-LIKE COMPOSITION OF THE CIRCULATING BILE ACID POOL IMPACTS ON PLASMA LDL CHOLESTEROL IN MICE. Atherosclerosis, 287, E14-E14. https://doi.org/10.1016/j.atherosclerosis.2019.06.038
van Zutphen, T., Bertolini, A., de Vries, H. D., Bloks, V. W., de Boer, J. F., Jonker, J. W., & Kuipers, F. (2019). Potential of Intestine-Selective FXR Modulation for Treatment of Metabolic Disease. In S. Fiorucci, & E. Distrutti (Eds.), Bile Acids and Their Receptors (pp. 207-234). (Handbook of Experimental Pharmacology). Springer. https://doi.org/10.1007/164_2019_233
Heeman, W., Dijkstra, K., Hoff, C., Koopal, S., Pierie, J.-P., Bouma, H., & Boerma, E. C. (2019). Application of laser speckle contrast imaging in laparoscopic surgery. Biomedical optics express, 10(4), 2010-2019. https://doi.org/10.1364/BOE.10.002010
Heeman, W., Steenbergen, W., van Dam, G., & Boerma, E. C. (2019). Clinical applications of laser speckle contrast imaging: a review. Journal of Biomedical Optics, 24(8), 1-11. https://doi.org/10.1117/1.JBO.24.8.080901
van Zutphen, T., Stroeve, J. H. M., Yang, J., Bloks, V. W., Jurdzinski, A., Roelofsen, H., Huijkman, N. C. A., van Dijk, T. H., Vonk, R. J., van Deursen, J., Staels, B., Groen, A. K., & Kuipers, F. (2019). FXR overexpression alters adipose tissue architecture in mice and limits its storage capacity leading to metabolic derangements[S]. Journal of Lipid Research, 60(9), 1547-1561. https://doi.org/10.1194/jlr.M094508
Zwarts, I., van Zutphen, T., Kruit, J. K., Liu, W., Oosterveer, M. H., Verkade, H. J., Uhlenhaut, N. H., & Jonker, J. W. (2019). Identification of the fructose transporter GLUT5 (SLC2A5) as a novel target of nuclear receptor LXR. Scientific Reports, 9(1), Article 9299. https://doi.org/10.1038/s41598-019-45803-x

2018

Beumeler, L. F. E., Waarsenburg, E. C., Booij, S. H., Scheurink, A., & Hoenders, H. J. R. (2018). Evaluation of a lifestyle intervention program in primary care on physical and mental health and quality of life of cancer survivors: A pilot study. European Journal of Integrative Medicine, 23, 1-5. https://doi.org/10.1016/j.eujim.2018.08.007
Visser, E., de Roos, N. M., Oosting, E., Endenburg, S. C., & Dronkers, J. J. (2018). Association Between Preoperative Vitamin D Status and Short-Term Physical Performance after Total Hip Arthroplasty: A Prospective Study. Annals of nutrition and metabolism, 73(3), 252-260. https://doi.org/10.1159/000492938

2017

Doktorova, M., Zwarts, I., van Zutphen, T., van Dijk, T. H., Bloks, V. W., Harkema, L., de Bruin, A., Downes, M., Evans, R. M., Verkade, H. J., & Jonker, J. W. (2017). Intestinal PPARĪ“ protects against diet-induced obesity, insulin resistance and dyslipidemia. Scientific Reports, 7(1), Article 846. https://doi.org/10.1038/s41598-017-00889-z

2016

Liu, W., Struik, D., Nies, V. J. M., Jurdzinski, A., Harkema, L., de Bruin, A., Verkade, H. J., Downes, M., Evans, R. M., van Zutphen, T., & Jonker, J. W. (2016). Effective treatment of steatosis and steatohepatitis by fibroblast growth factor 1 in mouse models of nonalcoholic fatty liver disease. Proceedings of the National Academy of Sciences of the United States of America, 113(8), 2288-2293. https://doi.org/10.1073/pnas.1525093113
Nies, V. J. M., Sancar, G., Liu, W., van Zutphen, T., Struik, D., Yu, R. T., Atkins, A. R., Evans, R. M., Jonker, J. W., & Downes, M. R. (2016). Fibroblast Growth Factor Signaling in Metabolic Regulation. Frontiers in endocrinology, 6, Article 193. https://doi.org/10.3389/fendo.2015.00193
van Zutphen, T., Ciapaite, J., Bloks, V. W., Ackereley, C., Gerding, A., Jurdzinski, A., de Moraes, R. A., Zhang, L., Wolters, J. C., Bischoff', R., Wanders, R. J., Houten, S. M., Bronte-Tinkew, D., Shatseva, T., Lewis, G. F., Groen, A. K., Reijngoud, D.-J., Bakker, B. M., Jonker, J. W., ... Bandsma, R. H. J. (2016). Malnutrition-associated liver steatosis and ATP depletion is caused by peroxisomal and mitochondrial dysfunction. Journal of Hepatology, 65(6), 1198-1208. https://doi.org/10.1016/j.jhep.2016.05.046
Sargent, G., van Zutphen, T., Shatseva, T., Zhang, L., Di Giovanni, V., Bandsma, R., & Kim, P. K. (2016). PEX2 is the E3 ubiquitin ligase required for pexophagy during starvation. The Journal of Cell Biology, 214(6), 677-690. https://doi.org/10.1083/jcb.201511034

2015

Bandsma, R. H. J., Ackerley, C., Koulajian, K., Zhang, L., van Zutphen, T., van Dijk, T. H., Xiao, C., Giacca, A., & Lewis, G. F. (2015). A low-protein diet combined with low-dose endotoxin leads to changes in glucose homeostasis in weanling rats. American Journal of Physiology - Endocrinology and Metabolism, 309(5), E466-E473. https://doi.org/10.1152/ajpendo.00090.2015

2014

van Zutphen, T., Todde, V., de Boer, R., Kreim, M., Hofbauer, H. F., Wolinski, H., Veenhuis, M., Klei, I. J. V. D., & Kohlwein, S. D. (2014). Lipid droplet autophagy in the yeast Saccharomyces cerevisiae. Molecular Biology of the Cell, 25(2), 290-301. https://doi.org/10.1091/mbc.E13-08-0448

2011

van Zutphen, T., Veenhuis, M., & van der Klei, I. J. (2011). Damaged peroxisomes are subject to rapid autophagic degradation in the yeast Hansenula polymorpha. Autophagy, 7(8), 863-872. https://doi.org/10.4161/auto.7.8.15697
van Zutphen, T., & van der Klei, I. J. (2011). Quantitative analysis of organelle abundance, morphology and dynamics. Current Opinion in Biotechnology, 22(1), 127-132. https://doi.org/10.1016/j.copbio.2010.10.015

2010

van Zutphen, T., Baerends, R. J. S., Susanna, K., de Jong, A., Kuipers, O. P., Veenhuis, M., & van der Klei, I. J. (2010). Adaptation of Hansenula polymorpha to methanol: A transcriptome analysis. BMC Genomics, 11(1). https://doi.org/10.1186/1471-2164-11-1
Zutphen, T. V. (2010). Proliferation and autophagic degradation of peroxisomes in Hansenula polymorpha. s.n.

2008

Zutphen, T. V., Veenhuis, M., & Klei, I. J. V. D. (2008). Pex14 is the sole component of the peroxisomal translocon that is required for pexophagy. Autophagy, 4(1), 63-66.
Zutphen, T. V., Klei, I. J. V. D., & Kiel, J. A. K. W. (2008). Pexophagy in Hansenula polymorpha. In D. J. Klionsky (Ed.), Autophagy: Lower Eukaryotes and non-Mammalian Systems (Vol. 1, pp. 197-215). (Methods in Enzymology; Vol. 451). Elsevier. https://doi.org/10.1016/S0076-6879(08)03214-X

2007

Stasyk, O. G., Van Zutphen, T., Kang, H. A., Stasyk, O. V., Veenhuis, M., & Sibirny, A. A. (2007). The role of Hansenula polymorpha MIG1 homologues in catabolite repression and pexophagy. Fems Yeast Research, 7(7), 1103-1113. https://doi.org/10.1111/j.1567-1364.2007.00286.x
Last modified:09 June 2023 8.36 p.m.