prof. dr. W.J. (Wim) Quax
Professor of Pharmaceutical Biology
Research
Research units:
Publications
Catalysis of amorpha-4,11-diene synthase unraveled and improved by mutability landscape guided engineering
Abdallah, I. I., van Merkerk, R., Klumpenaar, E. & Quax, W. J., 2-Jul-2018, In : Scientific Reports. 8, 1, 1 p., 9961.Research output: Contribution to journal › Article › Academic › peer-review
PvdQ Quorum Quenching Acylase Attenuates Pseudomonas aeruginosa Virulence in a Mouse Model of Pulmonary Infection
Utari, P. D., Setroikromo, R., Melgert, B. N. & Quax, W. J., 26-Apr-2018, In : Frontiers in Cellular and Infection Microbiology. 8, 12 p., 119.Research output: Contribution to journal › Article › Academic › peer-review
Novel RANKL DE-loop mutants antagonize RANK-mediated osteoclastogenesis
Wang, Y., van Assen, A. H. G., Dos Reis, C. R. R., Setroikromo, R., van Merkerk, R., Boersma, Y. L., Cool, R. H. & Quax, W. J., Aug-2017, In : Febs Journal. 284, 15, p. 2501-2512 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Deciphering Physiological Functions of AHL Quorum Quenching Acylases
Utari, P. D., Vogel, J. & Quax, W. J., 19-Jun-2017, In : Frontiers in Microbiology. 8, 13 p., 1123.Research output: Contribution to journal › Review article › Academic › peer-review
Towards Metabolic Engineering of Podophyllotoxin Production: Natural Products and Cancer Drug Discovery
Seegers, C., Setroikromo, R. & Quax, W. J., 2017, Medicine : Natural Products and Cancer Drug Discovery. InTechResearch output: Chapter in Book/Report/Conference proceeding › Chapter › Academic
Methyl jasmonate treatment increases podophyllotoxin production in Podophyllum hexandrum roots under glasshouse conditions
Seegers, C. L. C., Setroikromo, R., Tepper, P. G., Horvatovich, P., Peters, R. & Quax, W. J., Aug-2017, In : Plant and Soil. 417, 1-2, p. 117-126 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Penicillin V acylases from gram-negative bacteria degrade N-acylhomoserine lactones and attenuate virulence in Pseudomonas aeruginosa
Sunder, A. V., Utari, P. D., Ramasamy, S., van Merkerk, R., Quax, W. J. & Pundle, A., Mar-2017, In : Applied Microbiology and Biotechnology. 101, 6, p. 2383-2395 13 p.Research output: Contribution to journal › Article › Academic › peer-review
Receptor-specific TRAIL as a means to achieve targeted elimination of activated hepatic stellate cells
Arabpour, M., Cool, R., Faber, K. N., Quax, W. J. & Haisma, H. J., 2017, In : Journal of Drug Targeting. 25, 4, p. 360-369 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Quantitative antibody-free LC-MS/MS analysis of sTRAIL in sputum and saliva at the sub-ng/mL level
Wilffert, D., Donzelli, R., Asselman, A., Hermans, J., Govorukhina, N., ten Hacken, N. H. T., Quax, W. J., Merbel, van de, N. & Bischoff, R., 1-Oct-2016, In : Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences. 1032, p. 205-210 6 p.Research output: Contribution to journal › Article › Academic › peer-review
Insights into the Three-Dimensional Structure of Amorpha-4,11-diene Synthase and Probing of Plasticity Residues
Abdallah, I. I., Czepnik, M., van Merkerk, R. & Quax, W. J., Oct-2016, In : Journal of Natural Products. 79, 10, p. 2455-2463 9 p.Research output: Contribution to journal › Article › Academic › peer-review
Highly sensitive antibody-free mu LC-MS/MS quantification of rhTRAIL in serum
Wilffert, D., Asselman, A., Donzelli, R., Hermans, J., Govorukhina, N., Quax, W. J., Merbel, van de, N. & Bischoff, R., May-2016, In : Bioanalysis. 8, 9, p. 881-890 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Complete Genome Sequence of Bacillus subtilis subsp. subtilis Strain ∆6
Reuß, D. R., Thürmer, A., Daniel, R., Quax, W. J. & Stülke, J., 2016, In : Genome Announcements. 4, 4, p. 1-2 2 p., e00759-16.Research output: Contribution to journal › Article › Academic › peer-review
Using mutability landscapes of a promiscuous tautomerase to guide the engineering of enantioselective Michaelases
van der Meer, J-Y., Poddar, H., Baas, B-J., Miao, Y., Rahimi, M., Kunzendorf, A., van Merkerk, R., Tepper, P. G., Geertsema, E. M., Thunnissen, A-M. W. H., Quax, W. J. & Poelarends, G. J., 2016, In : Nature Communications. 7, 16 p., 10911.Research output: Contribution to journal › Article › Academic › peer-review
Metabolic engineering of Bacillus subtilis for terpenoid production
Guan, Z., Xue, D., Abdallah, I. I., Dijkshoorn, L., Setroikromo, R., Lv, G. & Quax, W. J., 15-Sep-2015, In : Applied Microbiology and Biotechnology. 99, 22, p. 9395-9406Research output: Contribution to journal › Article › Academic › peer-review
Enhanced C30 carotenoid production in Bacillus subtilis by systematic overexpression of MEP pathway genes
Xue, D., Abdallah, I. I., de Haan, I. E. M., Sibbald, M. J. J. B. & Quax, W. J., 9-Apr-2015, In : Applied Microbiology and Biotechnology. 99, 14, p. 5907-5915Research output: Contribution to journal › Article › Academic › peer-review
Press / Media
Uw bacteriën babbelen voortdurend met elkaar
07/10/2017
1 Media contribution
Press/Media: Expert Comment › Popular
Activities
Reflections on flurbiprofen eyedrops
Wim Quax (Examiner)2-Dec-2002Activity: Examination › Supervision of PhD students › Academic
Pharmacy Day 2018
Anna Salvati (Organiser), Amalia Dolga (Organiser), Matthew Groves (Organiser), Klaus Mathwig (Organiser), Peter Horvatovich (Organiser), Wim J. Quax (Organiser), Anne Lexmond (Organiser), Gillian Dempsey (Organiser)12-Jun-2018Activity: Participating in or organising an event › Organising an event › Academic
Quorum quenching acylases reducing bacterial virulence
Wim Quax (Speaker)15-Jun-2017Activity: Talk or presentation › Professional
Prizes
ID: 181545