prof. dr. W.J. (Wim) Quax

Professor of Pharmaceutical Biology

prof. dr. W.J. (Wim) Quax
Telephone:
E-mail:
w.j.quax rug.nl

Research

Publications
  1. Catalysis of amorpha-4,11-diene synthase unraveled and improved by mutability landscape guided engineering

    Abdallah, I. I., van Merkerk, R., Klumpenaar, E. & Quax, W. J., 2-Jul-2018, In : Scientific Reports. 8, 1, 9961.

    Research output: Contribution to journalArticleAcademicpeer-review

  2. PvdQ Quorum Quenching Acylase Attenuates Pseudomonas aeruginosa Virulence in a Mouse Model of Pulmonary Infection

    Utari, P. D., Setroikromo, R., Melgert, B. N. & Quax, W. J., 26-Apr-2018, In : Frontiers in Cellular and Infection Microbiology. 8, 12 p., 119.

    Research output: Contribution to journalArticleAcademicpeer-review

  3. Novel RANKL DE-loop mutants antagonize RANK-mediated osteoclastogenesis

    Wang, Y., van Assen, A. H. G., Dos Reis, C. R. R., Setroikromo, R., van Merkerk, R., Boersma, Y. L., Cool, R. H. & Quax, W. J., Aug-2017, In : Febs Journal. 284, 15, p. 2501-2512 12 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  4. Deciphering Physiological Functions of AHL Quorum Quenching Acylases

    Utari, P. D., Vogel, J. & Quax, W. J., 19-Jun-2017, In : Frontiers in Microbiology. 8, 13 p., 1123.

    Research output: Contribution to journalReview articleAcademicpeer-review

  5. Towards Metabolic Engineering of Podophyllotoxin Production: Natural Products and Cancer Drug Discovery

    Seegers, C., Setroikromo, R. & Quax, W. J., 2017, Medicine : Natural Products and Cancer Drug Discovery. InTech

    Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

  6. Methyl jasmonate treatment increases podophyllotoxin production in Podophyllum hexandrum roots under glasshouse conditions

    Seegers, C. L. C., Setroikromo, R., Tepper, P. G., Horvatovich, P., Peters, R. & Quax, W. J., Aug-2017, In : Plant and Soil. 417, 1-2, p. 117-126 10 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  7. Penicillin V acylases from gram-negative bacteria degrade N-acylhomoserine lactones and attenuate virulence in Pseudomonas aeruginosa

    Sunder, A. V., Utari, P. D., Ramasamy, S., van Merkerk, R., Quax, W. J. & Pundle, A., Mar-2017, In : Applied Microbiology and Biotechnology. 101, 6, p. 2383-2395 13 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  8. Receptor-specific TRAIL as a means to achieve targeted elimination of activated hepatic stellate cells

    Arabpour, M., Cool, R., Faber, K. N., Quax, W. J. & Haisma, H. J., 2017, In : Journal of Drug Targeting. 25, 4, p. 360-369 10 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  9. Insights into the Three-Dimensional Structure of Amorpha-4,11-diene Synthase and Probing of Plasticity Residues

    Abdallah, I. I., Czepnik, M., van Merkerk, R. & Quax, W. J., Oct-2016, In : Journal of Natural Products. 79, 10, p. 2455-2463 9 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  10. Highly sensitive antibody-free mu LC-MS/MS quantification of rhTRAIL in serum

    Wilffert, D., Asselman, A., Donzelli, R., Hermans, J., Govorukhina, N., Quax, W. J., Merbel, van de, N. & Bischoff, R., May-2016, In : Bioanalysis. 8, 9, p. 881-890 10 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  11. Complete Genome Sequence of Bacillus subtilis subsp. subtilis Strain ∆6

    Reuß, D. R., Thürmer, A., Daniel, R., Quax, W. J. & Stülke, J., 2016, In : Genome Announcements. 4, 4, p. 1-2 2 p., e00759-16.

    Research output: Contribution to journalArticleAcademicpeer-review

  12. Using mutability landscapes of a promiscuous tautomerase to guide the engineering of enantioselective Michaelases

    van der Meer, J-Y., Poddar, H., Baas, B-J., Miao, Y., Rahimi, M., Kunzendorf, A., van Merkerk, R., Tepper, P. G., Geertsema, E. M., Thunnissen, A-M. W. H., Quax, W. J. & Poelarends, G. J., 2016, In : Nature Communications. 7, 16 p., 10911.

    Research output: Contribution to journalArticleAcademicpeer-review

  13. Metabolic engineering of Bacillus subtilis for terpenoid production

    Guan, Z., Xue, D., Abdallah, I. I., Dijkshoorn, L., Setroikromo, R., Lv, G. & Quax, W. J., 15-Sep-2015, In : Applied Microbiology and Biotechnology. 99, 22, p. 9395-9406

    Research output: Contribution to journalArticleAcademicpeer-review

  14. Enhanced C30 carotenoid production in Bacillus subtilis by systematic overexpression of MEP pathway genes

    Xue, D., Abdallah, I. I., de Haan, I. E. M., Sibbald, M. J. J. B. & Quax, W. J., 9-Apr-2015, In : Applied Microbiology and Biotechnology. 99, 14, p. 5907-5915

    Research output: Contribution to journalArticleAcademicpeer-review

View all (321) »

Press / Media
  1. Uw bacteriën babbelen voortdurend met elkaar

    Wim Quax

    07/10/2017

    1 media contribution

    Press/Media: Expert CommentPopular

  2. Cancer medication by the roadside

    Wim Quax

    07/12/2016

    1 item of media coverage

    Press/Media: ResearchPopular

  3. Cancer medication by the roadside

    Wim Quax

    07/12/2016

    1 media contribution

    Press/Media: ResearchPopular

View all (3) »

Activities
  1. Reflections on flurbiprofen eyedrops

    Wim Quax (Examiner)
    2-Dec-2002

    Activity: ExaminationSupervision of PhD studentsAcademic

  2. Pharmacy Day 2018

    Anna Salvati (Organiser), Amalia Dolga (Organiser), Matthew Groves (Organiser), Klaus Mathwig (Organiser), Peter Horvatovich (Organiser), Wim J. Quax (Organiser), Anne Lexmond (Organiser), Gillian Dempsey (Organiser)
    12-Jun-2018

    Activity: Participating in or organising an eventOrganising an eventAcademic

  3. Quorum quenching acylases reducing bacterial virulence

    Wim Quax (Speaker)
    15-Jun-2017

    Activity: Talk or presentationProfessional

View all (14) »

Prizes
  1. NRLS DAAD Award

    Wim Quax (Recipient), 21-Oct-2016

    Prize: National/international honourAcademic

View all (1) »

View graph of relations

ID: 181545