prof. dr. S.C.D. (Sven) van Ijzendoorn

Hoogleraar

Faculteit Medische Wetenschappen/UMCG

Telefoon:

050 361 6209

050 361 6190 (fax)

Secretariaat:

050 361 6111

g.noppert umcg.nl

E-mail:

s.c.d.van.ijzendoorn umcg.nl

ORCID Research Portal

Publicaties

Par1b induces asymmetric inheritance of plasma membrane domains via LGN-dependent mitotic spindle orientation in proliferating hepatocytes

Slim, C. L., Lázaro-Diéguez, F., Bijlard, M., Toussaint, M. J. M., de Bruin, A., Du, Q., Müsch, A. & van Ijzendoorn, S. C. D., 17-dec-2013, In: PLOS BIOLOGY. 11, 12, 13 blz., e1001739.

Onderzoeksoutput: Article › › peer review

A molecular mechanism of intrahepatic cholestasis in osteo-oto-hepato-enteric syndrome

Zhou, Z., Lin, Y., Imhann, F., Verkade, H. J., Li, Q. & van IJzendoorn, S. C. D., 20-mei-2026, (E-pub ahead of print) In: Cellular and molecular gastroenterology and hepatology. 101805.

Onderzoeksoutput: Article › › peer review

A novel mechanism involving USP53-regulated BSEP trafficking underlies low-GGT intrahepatic cholestasis

Ding, J., She, H.-Y., Cheng, Y., Sun, H.-Y., Feng, J.-Y., Liu, T., Qiu, Y.-L., Wei, B.-X., Zhang, J., Su, Y., Li, Y.-Q., Zhang, J.-J., Chen, S.-Y., Wang, T., Yu, Y., van IJzendoorn, S. C. D., Wang, J.-S. & Xing, Q.-H., jun-2026, In: Hepatology (Baltimore, Md.). 83, 6, blz. 1383-1397 15 blz.

Onderzoeksoutput: Article › › peer review

Associations of Monocyte Glucocerebrosidase with Cognition and Cholinergic Innervation in GBA1 Parkinson's Disease

Slingerland, S., van der Zee, S., van Ijzendoorn, S. C. D., Slomp, A. C., Boertien, J. M., Meles, S. K., Kol, A., Geerlings, M. & van Laar, T., 13-apr-2026, (E-pub ahead of print) In: Movement Disorders.

Onderzoeksoutput: Article › › peer review

Generation and characterization of induced pluripotent stem cell lines from one Parkinson's disease patient carrying the GBA1 T369M variant and two variant-free controls

Hosseini Bondarabadi, M., Xu, M., Slingerland, S., de Leeuw, J., Sommer, I., Harmsen, H. J. M., van Laar, T. & van Ijzendoorn, S. C. D., jun-2026, In: Stem Cell Research. 93, 5 blz., 103983.

Onderzoeksoutput: Article › › peer review

Microvillus inclusion disease-associated MYO5B deficiency impairs endosome-to-mitochondrion iron transfer

Sun, C., Leng, C., Sun, M., Lin, Y., Xu, M., Martinez-Barriocanal, Á., Gerding, A., Kuipers, J., de Leeuw, J., Bakker, B. M., Arango, D. & van IJzendoorn, S. C. D., feb-2026, In: Gastroenterology report. 14, 15 blz., goag016.

Onderzoeksoutput: Article › › peer review

MYO5B Deficiency-Associated Cholestasis and the Role of the Bile Salt Export Pump

Zhou, Z. & van IJzendoorn, S. C. D., 5-jan-2026, In: Cells. 15, 1, 13 blz., 92.

Onderzoeksoutput: Review article › peer review

Odevixibat treatment for recurrent cholestasis in a patient with biallelic UNC45A variants causing osteo-oto-hepato-enteric syndrome

‘Support and Supervision Team’, Imhann, F., Zhou, Z. & Malcolm, C. F. S., apr-2026, In: JHEP Reports. 8, 4, 3 blz., 101710.

Onderzoeksoutput: Letter (Research letter) › › peer review

A liver-specific mouse model for MYO5B-associated cholestasis reveals a toxic gain-of-function as underlying disease mechanism

She, H. Y., Qiu, Y. L., Feng, J. Y., Cheng, Y., Chi, H., van IJzendoorn, S. C. D., Xing, Q. H. & Wang, J. S., 12-apr-2025, In: Biochemical and Biophysical Research Communications. 758, 9 blz., 151669.

Onderzoeksoutput: Article › › peer review

Age-Specific ADME Gene Expression in Infant Intestinal Enteroids

Streekstra, E. J., Scheer-Weijers, T., Bscheider, M., Fuerst-Recktenwald, S., Roth, A., van Ijzendoorn, S. C. D., Botden, S., de Boode, W., Stommel, M. W. J., Greupink, R., Russel, F. G. M., van de Steeg, E. & de Wildt, S. N., sep-2024, In: Molecular pharmaceutics. 21, 9, blz. 4347–4355 9 blz.

Onderzoeksoutput: Article › › peer review