prof. dr. S.C.D. (Sven) van Ijzendoorn

Hoogleraar

Faculteit Medische Wetenschappen/UMCG

Telefoon:

050 361 6209

050 361 6190 (fax)

Secretariaat:

050 361 6111

g.noppert umcg.nl

E-mail:

s.c.d.van.ijzendoorn umcg.nl

ORCID Research Portal

Publicaties

Par1b induces asymmetric inheritance of plasma membrane domains via LGN-dependent mitotic spindle orientation in proliferating hepatocytes

Slim, C. L., Lázaro-Diéguez, F., Bijlard, M., Toussaint, M. J. M., de Bruin, A., Du, Q., Müsch, A. & van Ijzendoorn, S. C. D., 17-dec.-2013, In: PLOS BIOLOGY. 11, 12, 13 blz., e1001739.

Onderzoeksoutput: Article › › peer review

Microvillus inclusion disease-associated MYO5B deficiency impairs endosome-to-mitochondrion iron transfer

Sun, C., Leng, C., Sun, M., Lin, Y., Xu, M., Martinez-Barriocanal, Á., Gerding, A., Kuipers, J., de Leeuw, J., Bakker, B. M., Arango, D. & van IJzendoorn, S. C. D., feb.-2026, In: Gastroenterology report. 14, blz. goag016

Onderzoeksoutput: Article › › peer review

MYO5B Deficiency-Associated Cholestasis and the Role of the Bile Salt Export Pump

Zhou, Z. & van IJzendoorn, S. C. D., 5-jan.-2026, In: Cells. 15, 1, 13 blz., 92.

Onderzoeksoutput: Review article › peer review

Odevixibat treatment for recurrent cholestasis in a patient with biallelic UNC45A variants causing osteo-oto-hepato-enteric syndrome

‘Support and Supervision Team’, apr.-2026, In: JHEP Reports. 8, 4, 101710.

Onderzoeksoutput › › peer review

A liver-specific mouse model for MYO5B-associated cholestasis reveals a toxic gain-of-function as underlying disease mechanism

She, H. Y., Qiu, Y. L., Feng, J. Y., Cheng, Y., Chi, H., van IJzendoorn, S. C. D., Xing, Q. H. & Wang, J. S., 12-apr.-2025, In: Biochemical and Biophysical Research Communications. 758, 9 blz., 151669.

Onderzoeksoutput: Article › › peer review

A novel mechanism involving USP53-regulated BSEP trafficking underlies low-GGT intrahepatic cholestasis

Ding, J., She, H.-Y., Cheng, Y., Sun, H.-Y., Feng, J.-Y., Liu, T., Qiu, Y.-L., Wei, B.-X., Zhang, J., Su, Y., Li, Y.-Q., Zhang, J.-J., Chen, S.-Y., Wang, T., Yu, Y., van IJzendoorn, S. C. D., Wang, J.-S. & Xing, Q.-H., 19-aug.-2025, (E-pub ahead of print) In: Hepatology (Baltimore, Md.). 37 blz.

Onderzoeksoutput: Article › › peer review

Age-Specific ADME Gene Expression in Infant Intestinal Enteroids

Streekstra, E. J., Scheer-Weijers, T., Bscheider, M., Fuerst-Recktenwald, S., Roth, A., van Ijzendoorn, S. C. D., Botden, S., de Boode, W., Stommel, M. W. J., Greupink, R., Russel, F. G. M., van de Steeg, E. & de Wildt, S. N., sep.-2024, In: Molecular pharmaceutics. 21, 9, blz. 4347–4355 9 blz.

Onderzoeksoutput: Article › › peer review

Nanoparticles targeting the intestinal Fc receptor enhance intestinal cellular trafficking of semaglutide

Pinto, S., Hosseini, M., Buckley, S. T., Yin, W., Garousi, J., Gräslund, T., van Ijzendoorn, S., Santos, H. A. & Sarmento, B., feb.-2024, In: Journal of Controlled Release. 366, blz. 621-636 16 blz.

Onderzoeksoutput: Article › › peer review

RhoA downregulation in the murine intestinal epithelium results in chronic Wnt activation and increased tumorigenesis

Dopeso, H., Rodrigues, P., Cartón-García, F., Macaya, I., Bilic, J., Anguita, E., Jing, L., Brotons, B., Vivancos, N., Beà, L., Sánchez-Martín, M., Landolfi, S., Hernandez-Losa, J., Ramon y Cajal, S., Nieto, R., Vicario, M., Farre, R., Schwartz, S., van Ijzendoorn, S. C. D.& Kobayashi, K., Martinez-Barriocanal, Á. & Arango, D., 19-apr.-2024, In: Iscience. 27, 4, 19 blz., 109400.

Onderzoeksoutput: Article › › peer review

Uncovering the Relationship between Genes and Phenotypes Beyond the Gut in Microvillus Inclusion Disease

Sun, M., Pylypenko, O., Zhou, Z., Xu, M., Li, Q., Houdusse, A. & van IJzendoorn, S. C. D., 2024, In: Cellular and molecular gastroenterology and hepatology. 17, 6, blz. 983-1005 23 blz.

Onderzoeksoutput: Review article › peer review