dr. S. Bergink

Telephone:
Secretariat:
E-mail:
s.bergink umcg.nl

Research

Research interests

Steven Bergink received his master in molecular biology at the university of Groningen. He obtained his PhD at the ErasmusMC in Rotterdam in the group of Jan Hoeijmakers. He continued with a postdoc at the Max Planck Institute of Biochemistry (Munich, Germany) in the group of Stefan Jentsch. During both his PhD and postdoctoral period he focused on the regulation of DNA repair mechanisms by posttranslational modifications of the ubiquitin family.

           Currently he is a group leader at the medical faculty in Groningen. His current research at the Department of Cell biology aims to investigate the intertwinement of DNA repair, protein quality control and neurodegeneration.

Publications
  1. Protein quality control in the nucleolus safeguards recovery of epigenetic regulators after heat shock

    Azkanaz, M., Rodríguez López, A., de Boer, B., Huiting, W., Angrand, P-O., Vellenga, E., Kampinga, H. H., Bergink, S., Martens, J. H., Schuringa, J. J. & van den Boom, V., 14-Jun-2019, In : eLife. 8, 27 p., 45205.

    Research output: Contribution to journalArticleAcademicpeer-review

  2. HSP40/DNAJ Chaperones

    Bergink, S., Kampinga, H. H., Kolbe Musskopf, M. & Preusser Mattos, E., 17-May-2018, In : eLS.

    Research output: Contribution to journalArticleAcademicpeer-review

  3. The N terminus of the small heat shock protein HSPB7 drives its polyQ aggregation-suppressing activity

    Wu, D., Vonk, J. J., Salles, F., Vonk, D., Haslbeck, M., Melki, R., Bergink, S. & Kampinga, H. H., 21-Jun-2019, In : The Journal of Biological Chemistry. 294, 25, p. 9985-9994 10 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  4. Myopathy associated BAG3 mutations lead to protein aggregation by stalling Hsp70 networks

    Meister-Broekema, M., Freilich, R., Jagadeesan, C., Rauch, J. N., Bengoechea, R., Motley, W. W., Kuiper, E. F. E., Minoia, M., Furtado, G. V., van Waarde, M. A. W. H., Bird, S. J., Rebelo, A., Zuchner, S., Pytel, P., Scherer, S. S., Morelli, F. F., Carra, S., Weihl, C. C., Bergink, S., Gestwicki, J. E. & Kampinga, H. H., 17-Dec-2018, In : Nature Communications. 9, 1, 14 p., 5342.

    Research output: Contribution to journalArticleAcademicpeer-review

  5. Astrocytic expression of the chaperone DNAJB6 results in non-cell autonomous protection in Huntington's disease

    Bason, M., Meister-Broekema, M., Alberts, N., Dijkers, P., Bergink, S., Sibon, O. C. M. & Kampinga, H. H., Apr-2019, In : Neurobiology of Disease. 124, p. 108-117 10 p.

    Research output: Contribution to journalArticleAcademicpeer-review

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