dr. S. Bergink

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s.bergink umcg.nl


Research interests

Steven Bergink received his master in molecular biology at the university of Groningen. He obtained his PhD at the ErasmusMC in Rotterdam in the group of Jan Hoeijmakers. He continued with a postdoc at the Max Planck Institute of Biochemistry (Munich, Germany) in the group of Stefan Jentsch. During both his PhD and postdoctoral period he focused on the regulation of DNA repair mechanisms by posttranslational modifications of the ubiquitin family.

           Currently he is a group leader at the medical faculty in Groningen. His current research at the Department of Cell biology aims to investigate the intertwinement of DNA repair, protein quality control and neurodegeneration.

  1. Insulin-like growth factor 2 (IGF2) protects against Huntington's disease through the extracellular disposal of protein aggregates

    Garcia-Huerta, P., Troncoso-Escudero, P., Wu, D., Thiruvalluvan, A., Cisternas-Olmedo, M., Henriquez, D. R., Plate, L., Chana-Cuevas, P., Saquel, C., Thielen, P., Longo, K. A., Geddes, B. J., Lederkremer, G. Z., Sharma, N., Shenkman, M., Naphade, S., Sardi, S. P., Spichiger, C., Richter, H. G., Court, F. A., Tshilenge, K. T., Ellerby, L. M., Wiseman, R. L., Gonzalez-Billault, C., Bergink, S., Vidal, R. L. & Hetz, C., 8-Jul-2020, In : Acta Neuropathologica. 140, 5, p. 737-764 28 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  2. Functional diversity between HSP70 paralogs due to variable interactions with specific co-chaperones

    Serlidaki, D., van Waarde, M. A. W. H., Rohland, L., Wentink, A. S., Dekker, S. L., Kamphuis, M. J., Boertien, J. M., Brunsting, J. F., Nillegoda, N. B., Bukau, B., Mayer, M. P., Kampinga, H. H. & Bergink, S., 22-May-2020, In : The Journal of Biological Chemistry. 295, 21, p. 7301-7316 17 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  3. DNAJB6, a Key Factor in Neuronal Sensitivity to Amyloidogenesis

    Thiruvalluvan, A., de Mattos, E. P., Brunsting, J. F., Bakels, R., Serlidaki, D., Barazzuol, L., Conforti, P., Fatima, A., Koyuncu, S., Cattaneo, E., Vilchez, D., Bergink, S., Boddeke, E. H. W. G., Copray, S. & Kampinga, H. H., 16-Apr-2020, In : Molecular Cell. 78, 2, p. 346-+ 22 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  4. Protein Quality Control Pathways at the Crossroad of Synucleinopathies

    De Mattos, E. P., Wentink, A., Nussbaum-Krammer, C., Hansen, C., Bergink, S., Melki, R. & Kampinga, H. H., 3-Apr-2020, In : Journal of Parkinson's Disease. 10, 2, p. 369-382 14 p.

    Research output: Contribution to journalReview articleAcademicpeer-review

  5. Protein quality control in the nucleolus safeguards recovery of epigenetic regulators after heat shock

    Azkanaz, M., Rodríguez López, A., de Boer, B., Huiting, W., Angrand, P-O., Vellenga, E., Kampinga, H. H., Bergink, S., Martens, J. H., Schuringa, J. J. & van den Boom, V., 14-Jun-2019, In : eLife. 8, 27 p., 45205.

    Research output: Contribution to journalArticleAcademicpeer-review

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Press / Media
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    Steven Bergink


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