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Practical matters How to find us dr. R.S.N. (Rudolf) Fehrmann

University Medical Center Groningen

dr. R.S.N. (Rudolf) Fehrmann

MD/PhD

dr. R.S.N. (Rudolf) Fehrmann

Faculty of Medical Sciences

Telephone:

+31 50 361 2587

E-mail:

r.s.n.fehrmann umcg.nl

Homepage ORCID Research Portal

Research interests

My practical and theoretical background enables me to take an integrative omics approach to identify driver genetic alterations, genes and biological pathways that are relevant for the pathophysiological behaviour and treatment response of tumors and rapidly translate these findings to clinical practice.

In addition to my training as a medical doctor, I completed one full year of Mathematics and Computer Science, after which I continued to obtain my MSc degree in Cognitive Science and Engineering.

In parallel to my medical studies, I worked for several years as a bio-informatician at the Department of Genetics, UMCG. In 2010, I obtained my PhD on high dimensional data analysis for new insights into ovarian cancer phenotypes, after which I continued as an affiliated post-doc at the Departments of Genetics and Medical Oncology (UMCG).

I followed the residency program in Internal Medicine / Medical Oncology and now work as a medical oncologist (staff member) at the department of Medical Oncology at the UMCG. In addition, I am a principal investigator at the Cancer Research Center Groningen in the research programmes: ‘Guided Treatment in Optimal Selected Cancer Patients (GUTS)’ and ‘Damage and Repair in Cancer Development and Cancer (DARE)’.

Publications

An mRNA expression-based signature for oncogene-induced replication-stress

Guerrero Llobet, S. , Bhattacharya, A. , Everts, M. , Kok, K. , van der Vegt, B. , Fehrmann, R. S. N. & van Vugt, M. A. T. M. , 18-Feb-2022 , In: ONCOGENE. 41 , 8 , p. 1216-1224 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

Cross-cohort gut microbiome associations with immune checkpoint inhibitor response in advanced melanoma

Lee, K. A., Thomas, A. M., Bolte, L. A. , Björk, J. R. , de Ruijter, L. K. , Armanini, F., Asnicar, F., Blanco-Miguez, A., Board, R., Calbet-Llopart, N., Derosa, L., Dhomen, N., Brooks, K., Harland, M., Harries, M., Leeming, E. R., Lorigan, P., Manghi, P., Marais, R., Newton-Bishop, J.& 20 others , Nezi, L. , Pinto, F. , Potrony, M. , Puig, S. , Serra-Bellver, P. , Shaw, H. M. , Tamburini, S. , Valpione, S. , Vijay, A. , Waldron, L. , Zitvogel, L. , Zolfo, M. , de Vries, E. G. E. , Nathan, P. , Fehrmann, R. S. N. , Bataille, V. , Hospers, G. A. P. , Spector, T. D. , Weersma, R. K. & Segata, N. , Mar-2022 , In: Nature Medicine. 28 , p. 535–544 28 p.

Research output: Contribution to journal › Article › Academic › peer-review

Immunogenicity after second and third mRNA-1273 vaccination doses in patients receiving chemotherapy, immunotherapy, or both for solid tumours

Oosting, S. F. , van der Veldt, A. A. M., Fehrmann, R. S. N. , GeurtsvanKessel, C. H., van Binnendijk, R. S., Dingemans, A-M. C., Smit, E. F., Hiltermann, T. J. N. , den Hartog, G., Jalving, M. , Westphal, T. T., Bhattacharya, A. , de Wilt, F., Boerma, A., van Zijl, L., Rimmelzwaan, G. F., Kvistborg, P., van Els, C. A. C. M., Rots, N. Y., van Baarle, D. & 2 others , Haanen, J. B. A. G. & de Vries, E. G. E. , 25-Apr-2022 , (E-pub ahead of print) In: Lancet Oncology.

Research output: Contribution to journal › Letter › Academic › peer-review

Intraoperative MET-receptor targeted fluorescent imaging and spectroscopy for lymph node detection in papillary thyroid cancer: novel diagnostic tools for more selective central lymph node compartment dissection

Jonker, P. K. C. , Metman, M. J. H. , Sondorp, L. H. J. , Sywak, M. S. , Gill, A. J. , Jansen, L. , Links, T. P. , van Diest, P. J. , van Ginhoven, T. M. , Löwik, C. W. G. M. , Nguyen, A. H. , Coppes, R. P. , Robinson, D. J. , van Dam, G. M. , van Hemel, B. M. , Fehrmann, R. S. N. & Kruijff, S. , 7-Apr-2022 , (E-pub ahead of print) In: European Journal of Nuclear Medicine and Molecular Imaging. 49 , p. 3557-3570 14 p.

Research output: Contribution to journal › Article › Academic › peer-review

Liver glycogen phosphorylase is upregulated in glioblastoma and provides a metabolic vulnerability to high dose radiation

Zois, C. E. , Hendriks, A. M. , Haider, S. , Pires, E. , Bridges, E. , Kalamida, D. , Voukantsis, D. , Lagerholm, B. C. , Fehrmann, R. S. N. , den Dunnen, W. F. A. , Tarasov, A. I. , Baba, O. , Morris, J. , Buffa, F. M. , McCullagh, J. S. O. , Jalving, M. & Harris, A. L. , 28-Jun-2022 , In: Cell death & disease. 13 , 6 , 15 p. , 573.

Research output: Contribution to journal › Article › Academic › peer-review

The gut wall's potential as a partner for precision oncology in immune checkpoint treatment

Hone Lopez, S. , Jalving, M. , Fehrmann, R. S. N. , Nagengast, W. B. , de Vries, E. G. E. & de Haan, J. J. , Jun-2022 , In: CANCER TREATMENT REVIEWS. 107 , 7 p. , 102406.

Research output: Contribution to journal › Review article › Academic › peer-review

Validation of Novel Molecular Imaging Targets Identified by Functional Genomic mRNA Profiling to Detect Dysplasia in Barrett’s Esophagus

Zhao, X. , Gabriels, R. Y. , Hooghiemstra, W. T. R. , Koller, M. , Meersma, G. J. , Buist-Homan, M. , Visser, L. , Robinson, D. J. , Tenditnaya, A. , Gorpas, D. , Ntziachristos, V. , Karrenbeld, A. , Kats-Ugurlu, G. , Fehrmann, R. S. N. & Nagengast, W. B. , 17-May-2022 , In: Cancers. 14 , 10 , 15 p. , 2462.

Research output: Contribution to journal › Article › Academic › peer-review

Colorectal anastomotic leak: Transcriptomic profile analysis

van Praagh, J. B. , de Wit, J. G. , Olinga, P. , de Haan, J. J. , Nagengast, W. B. , Fehrmann, R. S. N. & Havenga, K. , Mar-2021 , In: British Journal of Surgery. 108 , 3 , p. 326-333 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

COVID-19 vaccination: the VOICE for patients with cancer

van der Veldt, A. A. M. , Oosting, S. F. , Dingemans, A-M. C. , Fehrmann, R. S. N. , GeurtsvanKessel, C. , Jalving, M. , Rimmelzwaan, G. F. , Kvistborg, P. , Blank, C. U. , Smit, E. F. , Lemmens, V. E. E. P. , Hiltermann, T. J. N. , Koopmans, M. P. G. , Huckriede, A. L. W. , Rots, N. Y. , van Els, C. A. C. M. , van Baarle, D. , Haanen, J. B. A. G. & de Vries, E. G. E. , 15-Feb-2021 , In: Nature Medicine. 2 p.

Research output: Contribution to journal › Letter › Academic › peer-review

Gallbladder Cancer: Current Insights in Genetic Alterations and Their Possible Therapeutic Implications

Kuipers, H. , de Bitter, T. J. J. , de Boer, M. T. , van der Post, R. S. , Nijkamp, M. W. , de Reuver, P. R. , Fehrmann, R. S. N. & Hoogwater, F. J. H. , 20-Oct-2021 , In: Cancers. 13 , 21 , 20 p. , 5257.

Research output: Contribution to journal › Review article › Academic › peer-review

All (129) publications

Press/media

UMCG krijgt miljoen euro voor onderzoek naar therapie bij agressieve borstkanker

Marcel van Vugt & Rudolf Fehrmann

22/07/2022

Press/Media: Expert Comment › Popular

Prangende vragen én antwoorden over artificial intelligence in de zorg

Rudolf Fehrmann

02/09/2021

Press/Media: Expert Comment › Professional

Artificial Intelligence in Medical Oncology

Rudolf Fehrmann

02/09/2021

Press/Media: Expert Comment › Professional

Interview on Artificial Intelligence in Medical Oncology

Rudolf Fehrmann

28/08/2020

Press/Media: Expert Comment › Professional

Vlog: YAG Interdisciplinary Project

Marthe Walvoort & Rudolf Fehrmann

05/12/2018

Press/Media: Expert Comment › Popular

Looking back: ECR Lunch on work / life balance

Rudolf Fehrmann

27/08/2018

Press/Media: Other › Academic

UMCG krijgt subsidie voor onderzoek naar kanker

Rudolf Fehrmann

21/07/2017

Press/Media: Expert Comment › Popular

Press releases: Gene expression analysis identifies global gene dosage sensitivity in cancer

Rudolf Fehrmann

11/01/2014 → 20/01/2015

Press/Media: Research › Popular

All (8) press/media

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