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How to find us dr. R.S.N. (Rudolf) Fehrmann

Research interests

My practical and theoretical background enables me to take an integrative omics approach to identify driver genetic alterations, genes and biological pathways that are relevant for the pathophysiological behaviour and treatment response of tumors and rapidly translate these findings to clinical practice.

In addition to my training as a medical doctor, I completed one full year of Mathematics and Computer Science, after which I continued to obtain my MSc degree in Cognitive Science and Engineering.

In parallel to my medical studies, I worked for several years as a bio-informatician at the Department of Genetics, UMCG. In 2010, I obtained my PhD on high dimensional data analysis for new insights into ovarian cancer phenotypes, after which I continued as an affiliated post-doc at the Departments of Genetics and Medical Oncology (UMCG).

I followed the residency program in Internal Medicine / Medical Oncology and now work as a medical oncologist (staff member) at the department of Medical Oncology at the UMCG. In addition, I am a principal investigator at the Cancer Research Center Groningen in the research programmes: ‘Guided Treatment in Optimal Selected Cancer Patients (GUTS)’ and ‘Damage and Repair in Cancer Development and Cancer (DARE)’.

Publications

Colorectal anastomotic leak: transcriptomic profile analysis

COVID-19 vaccination: the VOICE for patients with cancer

Improving gene function predictions using independent transcriptional components

Clinical utility of circulating tumor DNA as a response and follow-up marker in cancer therapy

Comparison of Carboplatin With 5-Fluorouracil vs. Cisplatin as Concomitant Chemoradiotherapy for Locally Advanced Head and Neck Squamous Cell Carcinoma

Cyclin E expression is associated with high levels of replication stress in triple-negative breast cancer

Data-driven prioritization and preclinical evaluation of therapeutic targets in glioblastoma

Effect of a tailored exercise intervention during or after chemotherapy on cardiovascular morbidity in cancer patients.

Genome-wide association study of cardiovascular disease in testicular cancer patients treated with platinum-based chemotherapy

Immune microenvironment composition in non-small cell lung cancer and its association with survival

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Press/media

Interview on Artificial Intelligence in Medical Oncology

Vlog: YAG Interdisciplinary Project

Looking back: ECR Lunch on work / life balance

UMCG krijgt subsidie voor onderzoek naar kanker

Press releases: Gene expression analysis identifies global gene dosage sensitivity in cancer

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