dr. R.S.N. (Rudolf) Fehrmann
MD/PhD
Research
Research units:
Research interests
My practical and theoretical background enables me to take an integrative omics approach to identify driver genetic alterations, genes and biological pathways that are relevant for the pathophysiological behaviour and treatment response of tumors and rapidly translate these findings to clinical practice.
In addition to my training as a medical doctor, I completed one full year of Mathematics and Computer Science, after which I continued to obtain my MSc degree in Cognitive Science and Engineering.
In parallel to my medical studies, I worked for several years as a bio-informatician at the Department of Genetics, UMCG. In 2010, I obtained my PhD on high dimensional data analysis for new insights into ovarian cancer phenotypes, after which I continued as an affiliated post-doc at the Departments of Genetics and Medical Oncology (UMCG).
I followed the residency program in Internal Medicine / Medical Oncology and now work as a medical oncologist (staff member) at the department of Medical Oncology at the UMCG. In addition, I am a principal investigator at the Cancer Research Center Groningen in the research programmes: ‘Guided Treatment in Optimal Selected Cancer Patients (GUTS)’ and ‘Damage and Repair in Cancer Development and Cancer (DARE)’.
Publications
Data-driven prioritization and preclinical evaluation of therapeutic targets in glioblastoma
Brahm, C. G., Abdul, U. K., Houweling, M., van Linde, M. E., Lagerweij, T., Verheul, H. M. W., Westerman, B. A., Walenkamp, A. M. E. & Fehrmann, R. S. N., 5-Jan-2021, In : Neuro-oncology advances. 2, 1, p. vdaa151Research output: Contribution to journal › Article › Academic › peer-review
Effect of a tailored exercise intervention during or after chemotherapy on cardiovascular morbidity in cancer patients.
van der Schoot, G. G. F. G. F., Ormel, H. L., Westerink, N-D. L., Van der Velden, A., Poppema, B. J., Fehrmann, R. S. N., Lefrandt, J. D., van Roon, A. M., van Melle, J., Van der Meer, P., Wempe, J. B., ten Wolde, M., Stel, J., Vrieling, A. H., de Boer, N., May, A. M., Elias, S. G., Gietema, J. A. & Walenkamp, A. M. E., 20-May-2020, In : Journal of Clinical Oncology. 38, 15, 2 p.Research output: Contribution to journal › Meeting Abstract › Academic
Overexpression of Cyclin E1 or Cdc25A leads to replication stress, mitotic aberrancies, and increased sensitivity to replication checkpoint inhibitors
Kok, Y. P., Guerrero Llobet, S., Schoonen, P. M., Everts, M., Bhattacharya, A., Fehrmann, R. S. N., van den Tempel, N. & van Vugt, M. A. T. M., 7-Oct-2020, In : Oncogenesis. 9, 10, 15 p., 88.Research output: Contribution to journal › Article › Academic › peer-review
Genome-wide association study of cardiovascular disease in testicular cancer patients treated with platinum-based chemotherapy
Steggink, L. C., Boer, H., Meijer, C., Lefrandt, J. D., Terstappen, L. W. M. M., Fehrmann, R. S. N. & Gietema, J. A., 3-Oct-2020, In : Pharmacogenomics journal. 13 p.Research output: Contribution to journal › Article › Academic › peer-review
Cyclin E expression is associated with high levels of replication stress in triple-negative breast cancer
Guerrero Llobet, S., van der Vegt, B., Jongeneel, E., Bense, R. D., Zwager, M. C., Schröder, C. P., Everts, M., Fehrmann, R. S. N., de Bock, G. H. & van Vugt, M. A. T. M., 7-Sep-2020, In : NPJ Breast Cancer. 6, 1, 13 p., 40.Research output: Contribution to journal › Article › Academic › peer-review
Datasets
Data to: Evidence Based Selection of Housekeeping Genes
de Jonge, H. (Creator), Fehrmann, R. (Creator), de Bont, E. (Creator), Hofstra, R. M. W. (Creator), Gerbens, F. (Creator), Kamps, W. (Creator), Vries, de, L. (Creator), Zee, van der, A. (Creator), te Meerman, G. (Creator) & Elst, ter, A. (Creator), University of Groningen, 19-Sep-2007
https://figshare.com/articles/Evidence_Based_Selection_of_Housekeeping_Genes/151673
Dataset
Prizes
Mandema-stipendium
Fehrmann, Rudolf (Recipient), 2012
Prize: Fellowship awarded competitively › Academic
MD/PhD scholarship
Fehrmann, Rudolf (Recipient), 2006
Prize: Fellowship awarded competitively › Academic
Activities
ESMO Congress 2021 (Event)
Rudolf Fehrmann (Member)
2019 → 2021Activity: Membership › Membership of committee › Academic
Frontiers in Oncology (Journal)
Rudolf Fehrmann (Editorial board member)
2019Activity: Publication peer-review and editorial work › Editorial activity › Academic
Frontiers in Genetics (Journal)
Rudolf Fehrmann (Editorial board member)
2019Activity: Publication peer-review and editorial work › Editorial activity › Academic
Press / Media
Vlog: YAG Interdisciplinary Project
Marthe Walvoort & Rudolf Fehrmann
05/12/2018
1 Media contribution
Press/Media: Expert Comment › Popular
ID: 228591