dr. R.S.N. (Rudolf) Fehrmann
MD/PhD
Research
Research units:
Research interests
My practical and theoretical background enables me to take an integrative omics approach to identify driver genetic alterations, genes and biological pathways that are relevant for the pathophysiological behaviour and treatment response of tumors and rapidly translate these findings to clinical practice.
In addition to my training as a medical doctor, I completed one full year of Mathematics and Computer Science, after which I continued to obtain my MSc degree in Cognitive Science and Engineering.
In parallel to my medical studies, I worked for several years as a bio-informatician at the Department of Genetics, UMCG. In 2010, I obtained my PhD on high dimensional data analysis for new insights into ovarian cancer phenotypes, after which I continued as an affiliated post-doc at the Departments of Genetics and Medical Oncology (UMCG).
I followed the residency program in Internal Medicine / Medical Oncology and now work as a medical oncologist (staff member) at the department of Medical Oncology at the UMCG. In addition, I am a principal investigator at the Cancer Research Center Groningen in the research programmes: ‘Guided Treatment in Optimal Selected Cancer Patients (GUTS)’ and ‘Damage and Repair in Cancer Development and Cancer (DARE)’.
Publications
MAPK pathway activity plays a key role in PD-L1 expression of lung adenocarcinoma cells
Stutvoet, T. S., Kol, A., de Vries, E. G. E., de Bruyn, M., Fehrmann, R. S. N., van Scheltinga, A. G. T. T. & de Jong, S., Sep-2019, In : JOURNAL OF PATHOLOGY. 249, 1, p. 52-64 13 p.Research output: Contribution to journal › Article › Academic › peer-review
CD47 expression defines efficacy of rituximab with CHOP in Non-Germinal Center B-cell (non-GCB) Diffuse Large B-Cell Lymphoma patients (DLBCL), but not in GCB DLBCL
Bouwstra, R., He, Y., de Boer, J. W., Kooistra, H., Cendrowicz, E., Fehrmann, R. S. N., Ammatuna, E., Eulenburg, C., Nijland, M., Huls, G., Bremer, E. & van Meerten, T., 13-Aug-2019, In : Cancer immunology research.Research output: Contribution to journal › Article › Academic › peer-review
Consideration of breast cancer subtype in targeting the androgen receptor
Venema, C. M., Bense, R. D., Steenbruggen, T. G., Nienhuis, H. H., Qiu, S-Q., van Kruchten, M., Brown, M., Tamimi, R. M., Hospers, G. A. P., Schröder, C. P., Fehrmann, R. S. N. & de Vries, E. G. E., Aug-2019, In : Pharmacology & Therapeutics. 200, p. 135-147 13 p.Research output: Contribution to journal › Review article › Academic › peer-review
Perioperative systemic therapy and cytoreductive surgery with HIPEC versus upfront cytoreductive surgery with HIPEC alone for isolated resectable colorectal peritoneal metastases: protocol of a multicentre, open-label, parralel-group, phase II-III, randomised, superiority study (CAIRO6)
DPOG & DCCG, 25-Apr-2019, In : BMC Cancer. 19, 15 p., 390.Research output: Contribution to journal › Article › Academic › peer-review
Transcriptional regulators CITED2 and PU.1 cooperate in maintaining hematopoietic stem cells
Mattes, K., Geugien, M., Korthuis, P. M., Brouwers-Vos, A. Z., Fehrmann, R. S. N., Todorova, T. I., Steidl, U., Vellenga, E. & Schepers, H., May-2019, In : Experimental Hematology. 73, p. 38-49 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Datasets
Data to: Evidence Based Selection of Housekeeping Genes
de Jonge, H. (Creator), Fehrmann, R. (Creator), de Bont, E. (Creator), Hofstra, R. M. W. (Creator), Gerbens, F. (Creator), Kamps, W. (Creator), Vries, de, E. G. E. (Creator), Zee, van der, A. (Creator), te Meerman, G. (Creator), Elst, ter, A. (Creator), University of Groningen, 19-Sep-2007
https://figshare.com/articles/Evidence_Based_Selection_of_Housekeeping_Genes/151673
Dataset
Prizes
Mandema-stipendium
Rudolf Fehrmann (Recipient), 2012
Prize: Fellowship awarded competitively › Academic
MD/PhD scholarship
Rudolf Fehrmann (Recipient), 2006
Prize: Fellowship awarded competitively › Academic
Activities
European Research Council (ERC) (External organisation)
Rudolf Fehrmann (Reviewer)2018 → …Activity: Membership › Membership of committee › Academic
Dutch Cancer Society (KWF Kankerbestrijding) (External organisation)
Rudolf Fehrmann (Reviewer)2018Activity: Membership › Membership of committee › Academic
Dutch Society of Internal Medicine (NIV) (External organisation)
Rudolf Fehrmann (Member)2010 → …Activity: Membership › Membership of network › Professional
Press / Media
Vlog: YAG Interdisciplinary Project
Marthe Walvoort & Rudolf Fehrmann
05/12/2018
1 media contribution
Press/Media: Expert Comment › Popular
ID: 228591