dr. R. Oerlemans

Faculteit Science and Engineering

Telefoon:

050 36 33296

E-mail:

r.oerlemans rug.nl

ORCID Research Portal

Publicaties

Characterization and Crystal Structure Elucidation of the L-Homoserine O-Succinyltransferase MetXS from Cupriavidus necator H16

Meier, H. P. F., Oerlemans, R., Terholsen, H., Groves, M. R., Lauterbach, L. & Schmidt, S., 20-jul-2026, (Submitted) ChemRxiv, 9 blz.

Onderzoeksoutput: Voordruk ›

Decoding and Reprogramming Redox Partner Specificity in Rieske Oxygenases for Enhanced Catalytic Activity

Miao, H., Oerlemans, R., Hagedoorn, P.-L. & Schmidt, S., 6-apr-2026, (Submitted) BioRxiv, 24 blz.

Onderzoeksoutput: Voordruk ›

Repurposing of Inhibitors of Plasmodial Aspartate Transcarbamoylase Toward Trypanosoma Cruzi

Chen, S., Cal, M., Mondile, Q., Oerlemans, R., Shashikant, M. M., Dömling, A. S. S., Bishop, Ö. T., Mäser, P. & Groves, M. R., 27-mrt-2026, In: ChemMedChem. 21, 6, 9 blz., e202500817.

Onderzoeksoutput › › peer review

Ugi-Tetrazole-Derived α-Aminomethyl Scaffolds Reveal Unexpected Binding Modes in SARS-CoV-2 3CLpro

van der Straat, R., Oerlemans, R., Cong, Y., Boxma, J., Bulai, R. G., Río-Bergé, C., Koekemoer, L., Zarganes Tzitzikas, T., Guan, Z., Marples, P. G., Reggiori, F., Groves, M. & Dömling, A., 9-apr-2026, In: ACS Medicinal Chemistry Letters. 17, 4, blz. 856-865 10 blz.

Onderzoeksoutput › › peer review

1-Deoxy-D-xylulose 5-phosphate synthase: Structural perspectives on an essential enzyme in isoprenoid biosynthesis

Gawriljuk, V. O., Oerlemans, R., Reddem, E. R., Gierse, R. M., Hirsch, A. K. H. & Groves, M. R., sep-2025, In: Journal of Structural Biology. 217, 3, 14 blz., 108236.

Onderzoeksoutput › peer review

Borrow or build: harnessing drug repurposing and structure-based design to address infectious diseases

Oerlemans, R., 2025, [Groningen]: University of Groningen. 147 blz.

Onderzoeksoutput

New homocysteine consumption assay for high-throughput screening of human Cystathionine-β-synthase

Nakládal, D., Oerlemans, R., Molitorisová, M., Chomaničová, N., Zorkócy, G., Yoseif, C., van der Graaf, A. C., Stuchlík, S., Krenning, G., Groves, M. R., Heeres, A., Levarski, Z., Kyselovič, J., Henning, R. H. & Deelman, L. E., apr-2025, In: SLAS discovery : advancing life sciences R & D. 32, 9 blz., 100234.

Onderzoeksoutput › › peer review

Cryo-EM structure of 1-deoxy-D-xylulose 5-phosphate synthase DXPS from Plasmodium falciparum reveals a distinct N-terminal domain

Gawriljuk, V. O., Godoy, A. S., Oerlemans, R., Welker, L. A. T., Hirsch, A. K. H. & Groves, M. R., dec-2024, In: Nature Communications. 15, 1, 11 blz., 6642.

Onderzoeksoutput › › peer review

Engineering a Plant Polyketide Synthase for the Biosynthesis of Methylated Flavonoids

Peng, B., Zhang, L., He, S., Oerlemans, R., Quax, W. J., Groves, M. R. & Haslinger, K., 10-jan-2024, In: Journal of Agricultural and Food Chemistry. 72, 1, blz. 529–539 11 blz.

Onderzoeksoutput › › peer review