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University Medical Center Groningen

dr. P.J. van der Most

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Faculty of Medical Sciences

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p.j.van.der.most umcg.nl

ORCID Research Portal

Research interests

Peter van der Most is a post-doc researcher at the unit of Genetic Epidemiology & Bioinformatics. He graduated in 2008 at the University of Groningen (bachelor in Life Science & Technology; master in Behavioural & Cognitive Neuroscience), and is interested in the intersection of biology, medicine and technology. Following graduation, he worked for two years at the department of Behavioural Biology with Prof. Simon Verhulst. There he used meta-analysis to study trade-offs between growth and immunity, and between quality and quantity of offspring in birds. Subsequently Peter van der Most wrote his PhD thesis on novel statistical methods and the development of quality-control tools for (epi-)genome-wide analysis at the unit of Genetic Epidemiology with Prof. Harold Snieder.

Publications

Author Correction: The power of genetic diversity in genome-wide association studies of lipids (Nature, (2021), 600, 7890, (675-679), 10.1038/s41586-021-04064-3)

Global Lipids Genetics Consortium, VA Million Veteran Program, Graham, S. E., Clarke, S. L., Wu, K. H. H., Kanoni, S., Zajac, G. J. M., Ramdas, S., Surakka, I., Ntalla, I., Vedantam, S., Winkler, T. W., Locke, A. E., Marouli, E., Hwang, M. Y., Han, S., Narita, A., Choudhury, A., Bentley, A. R., Ekoru, K., & 32 othersVerma, A., Trivedi, B., Martin, H. C., Hunt, K. A., Hui, Q., Klarin, D., Zhu, X., Thorleifsson, G., Helgadottir, A., Gudbjartsson, D. F., Holm, H., Olafsson, I., Akiyama, M., Sakaue, S., Zhao, W., Zhao, J. H., Verweij, N., Benjamins, J. W., Le, P., Wang, Y. X., van der Most, P. J., van der Laan, S. W., Wang, J. S., Asselbergs, F. W., Oldehinkel, A. J., Snieder, H., Penninx, B., Kumari, M., van der Harst, P., Huang, W., Kim, Y. J. & de Vries, P. S., Jun-2023, In: Nature. 618, p. E19-E20

Research output: Contribution to journal › Erratum

Genetic insights into resting heart rate and its role in cardiovascular disease

DCCT/EDIC Research Group, 2-Aug-2023, In: Nature Communications. 14, 21 p., 4646.

Research output: Contribution to journal › Article › Academic › peer-review

Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus

eQTLGen Consortium, Mathieson, I., Day, F. R., Barban, N., Tropf, F. C., Brazel, D. M., Vaez, A., van Zuydam, N., Bitarello, B. D., Gardner, E. J., Akimova, E. T., Azad, A., Bergmann, S., Bielak, L. F., Boomsma, D. I., Bosak, K., Brumat, M., Buring, J. E., Cesarini, D., Chasman, D. I., & 32 othersChavarro, J. E., Cocca, M., Concas, M. P., Davey Smith, G., Davies, G., Deary, I. J., Esko, T., Faul, J. D., Franco, O., Ganna, A., Gaskins, A. J., Gelemanovic, A., de Geus, E. J. C., Gieger, C., Girotto, G., Gopinath, B., Grabe, H. J., Gunderson, E. P., Hayward, C., He, C., van Heemst, D., Hill, W. D., Kamali, Z., van der Most, P. J., Nolte, I. M., Penninx, B. W. J. H., Swertz, M. A., Zhao, J. H., Zhao, W., Snieder, H., Mills, M. C. & Perry, J. R. B., May-2023, In: Nature Human Behaviour. 7, p. 790–801 12 p.

Research output: Contribution to journal › Article › Academic › peer-review

Understanding the genetic complexity of puberty timing across the allele frequency spectrum

ABCTB Investigators, Kentistou, K. A., Kaisinger, L. R., Stankovic, S., Vaudel, M., de Oliveira, E. M., Messina, A., Walters, R. G., Liu, X., Busch, A. S., Helgason, H., Thompson, D. J., Santon, F., Petricek, K. M., Zouaghi, Y., Huang-Doran, I., Gudbjartsson, D. F., Bratland, E., Lin, K., Gardner, E. J., & 33 othersZhao, Y., Jia, R., Terao, C., Riggan, M., Bolla, M. K., Yazdanpanah, M., Yazdanpanah, N., Bradfield, J. P., Broer, L., Campbell, A., Chasman, D. I., Cousminer, D. L., Franceschini, N., Franke, L. H., Girotto, G., He, C., Järvelin, M-R., Joshi, P. K., Kamatani, Y., Karlsson, R., Luan, J., Lunetta, K. L., Mägi, R., Mangino, M., Smith, A. V., van der Most, P. J., Hübner, H., Nolte, I. M., Oldehinkel, A. J., Alizadeh, B. Z., Snieder, H., Perry, J. R. B. & Ong, K. K., 20-Jun-2023, MedRxiv.

Research output: Working paper › Preprint › Academic

A genome-wide association study of total child psychiatric problems scores

Neumann, A., Nolte, I. M., Pappa, I., Ahluwalia, T. S., Pettersson, E., Rodriguez, A., Whitehouse, A., van Beijsterveldt, C. E. M., Benyamin, B., Hammerschlag, A. R., Helmer, Q., Karhunen, V., Krapohl, E., Lu, Y., van der Most, P. J., Palviainen, T., St Pourcain, B., Seppälä, I., Suarez, A., Vilor-Tejedor, N., & 41 othersTiesler, C. M. T., Wang, C., Wills, A., Zhou, A., Alemany, S., Bisgaard, H., Bønnelykke, K., Davies, G. E., Hakulinen, C., Henders, A. K., Hyppönen, E., Stokholm, J., Bartels, M., Hottenga, J-J., Heinrich, J., Hewitt, J., Keltikangas-Järvinen, L., Korhonen, T., Kaprio, J., Lahti, J., Lahti-Pulkkinen, M., Lehtimäki, T., Middeldorp, C. M., Najman, J. M., Pennell, C., Power, C., Oldehinkel, A. J., Plomin, R., Räikkönen, K., Raitakari, O. T., Rimfeld, K., Sass, L., Snieder, H., Standl, M., Sunyer, J., Williams, G. M., Bakermans-Kranenburg, M. J., Boomsma, D. I., van IJzendoorn, M. H., Hartman, C. A. & Tiemeier, H., 22-Aug-2022, In: PLoS ONE. 17, 8, 23 p., e0273116.

Research output: Contribution to journal › Article › Academic › peer-review

A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids

Ramdas, S., Judd, J., Graham, S. E., Kanoni, S., Wang, Y., Surakka, I., Wenz, B., Million Veterans Program, Clarke, S. L., Chesi, A., Wells, A., Bhatti, K. F., Vedantam, S., Winkler, T. W., Locke, A. E., Marouli, E., Zajac, G. J. M., Wu, K-H. H., Ntalla, I., Hui, Q., & 31 othersKlarin, D., Hilliard, A. T., Wang, Z., Xue, C., Thorleifsson, G., Helgadottir, A., Gudbjartsson, D. F., Holm, H., Olafsson, I., Hwang, M. Y., Han, S., Akiyama, M., Zhao, W., Zhao, J-H., Le, P., Verweij, N., Benjamins, J. W., Wang, Y. X., van der Most, P. J., van der Laan, S. W., Wang, J-S., Asselbergs, F. W., Oldehinkel, A. J., Snieder, H., Penninx, B., Kumari, M., van der Harst, P., Huang, W., Kim, Y. J., de Vries, P. S. & Zhu, X., 4-Aug-2022, In: American Journal of Human Genetics. 109, 8, p. 1366-1387 22 p.

Research output: Contribution to journal › Article › Academic › peer-review

A saturated map of common genetic variants associated with human height

23andMe Res Team, VA Million Vet Program, DiscovEHR DiscovEHR MyCode Communi, eEMERGE Elect Med Records Genomics, Lifelines Cohort Study, PRACTICAl Consortium, Understanding Soc Sci Grp, Yengo, L., Vedantam, S., Marouli, E., Sidorenko, J., Bartell, E., Sakaue, S., Graff, M., Eliasen, A. U., Jiang, Y., Raghavan, S., Miao, J., Arias, J. D., Graham, S. E., & 37 othersMukamel, R. E., Spracklen, C. N., Yin, X., Chen, S-H., Ferreira, T., Highland, H. H., Ji, Y., Karaderi, T., Lin, K., Lull, K., Malden, D. E., Medina-Gomez, C., Ani, A., Demirkan, A., Huang, J., Kim, Y. J., Le, P., Nolte, I. M., Raven, D., Smith, A., van der Laan, S. W., van der Most, P. J., Verweij, N., Xie, T., Zhao, J-H., Zhao, W., Asselbergs, F. W., Hartman, C. A., Huang, W., Kumari, M., Oldehinkel, A. J., Penninx, B. W. J. H., Rienstra, M., Snieder, H., van der Harst, P., Wang, Y. X. & Visscher, P. M., Oct-2022, In: Nature. 610, p. 704–712 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals

Lifelines Cohort Study, VA Million Veteran Program, DiscovEHR/MyCode , Winkler, T. W., Rasheed, H., Teumer, A., Gorski, M., Rowan, B. X., Stanzick, K. J., Thomas, L. F., Tin, A., Hoppmann, A., Chu, A. Y., Tayo, B., Thio, C. H. L., Cusi, D., Chai, J-F., Sieber, K. B., Horn, K., Li, M., & 34 othersScholz, M., Cocca, M., Wuttke, M., van der Most, P. J., Yang, Q., Ghasemi, S., Nutile, T., Li, Y., Pontali, G., Günther, F., Dehghan, A., Correa, A., Parsa, A., Feresin, A., de Vries, A. P. J., Zonderman, A. B., Smith, A. V., Oldehinkel, A. J., De Grandi, A., Rosenkranz, A. R., Franke, A., Teren, A., Penninx, B. W. J. H., Hartman, C. A., Snieder, H., Nolte, I. M., de Borst, M. H., Verweij, N., van der Harst, P., Gansevoort, R. T., Bakker, S. J. L., Huang, W., Wang, Y. X. & Heid, I. M., 13-Jun-2022, In: Communications biology. 5, 1, 20 p., 580.

Research output: Contribution to journal › Article › Academic › peer-review

Genetic Determinants of Serum Calcification Propensity and Cardiovascular Outcomes in the General Population

de Haan, A., Ahmadizar, F., van der Most, P. J., Thio, C. H. L., Kamali, Z., Ani, A., Ghanbari, M., Chaker, L., van Meurs, J., Ikram, M. K., van Goor, H., Bakker, S. J. L., van der Harst, P., Snieder, H., Kavousi, M., Pasch, A., Eijgelsheim, M. & de Borst, M. H., 14-Jan-2022, In: Frontiers in cardiovascular medicine. 8, 11 p., 809717.

Research output: Contribution to journal › Article › Academic › peer-review

Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies

Lifelines Cohort Study, Gorski, M., Rasheed, H., Teumer, A., Thomas, L. F., Graham, S. E., Sveinbjornsson, G., Winkler, T. W., Günther, F., Stark, K. J., Chai, J-F., Tayo, B. O., Wuttke, M., Li, Y., Tin, A., Ahluwalia, T. S., Ärnlöv, J., Åsvold, B. O., Bakker, S. J. L., Banas, B., & 31 othersBansal, N., Biggs, M. L., Biino, G., Böhnke, M., Boerwinkle, E., Bottinger, E. P., Brenner, H., Brumpton, B., Carroll, R. J., Chaker, L., Chalmers, J., Chee, M-L., Chee, M-L., Cheng, C-Y., Chu, A. Y., Ciullo, M., Cocca, M., Cook, J. P., Coresh, J., Cusi, D., de Borst, M. H., Degenhardt, F., Eckardt, K-U., Gansevoort, R. T., Nolte, I. M., Penninx, B. W. J. H., Snieder, H., Thio, C. H. L., van der Harst, P., van der Most, P. J. & Verweij, N., Sept-2022, In: Kidney International. 102, 3, p. 624-639 16 p.

Research output: Contribution to journal › Article › Academic › peer-review

All (117) publications

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