dr. P.J. van der Most

Faculty of Medical Sciences

Telephone:

+31 50 361 5741

E-mail:

p.j.van.der.most umcg.nl

ORCID Research Portal

Research interests

Peter van der Most is a post-doc researcher at the unit of Genetic Epidemiology & Bioinformatics. He graduated in 2008 at the University of Groningen (bachelor in Life Science & Technology; master in Behavioural & Cognitive Neuroscience), and is interested in the intersection of biology, medicine and technology. Following graduation, he worked for two years at the department of Behavioural Biology with Prof. Simon Verhulst. There he used meta-analysis to study trade-offs between growth and immunity, and between quality and quantity of offspring in birds. Subsequently Peter van der Most wrote his PhD thesis on novel statistical methods and the development of quality-control tools for (epi-)genome-wide analysis at the unit of Genetic Epidemiology with Prof. Harold Snieder.

Publications

A genome-wide association study of total child psychiatric problems scores

Neumann, A., Nolte, I. M. , Pappa, I., Ahluwalia, T. S., Pettersson, E., Rodriguez, A., Whitehouse, A., van Beijsterveldt, C. E. M., Benyamin, B., Hammerschlag, A. R., Helmer, Q., Karhunen, V., Krapohl, E., Lu, Y., van der Most, P. J. , Palviainen, T., St Pourcain, B., Seppälä, I., Suarez, A., Vilor-Tejedor, N., & 41 others Tiesler, C. M. T. , Wang, C. , Wills, A. , Zhou, A. , Alemany, S. , Bisgaard, H. , Bønnelykke, K. , Davies, G. E. , Hakulinen, C. , Henders, A. K. , Hyppönen, E. , Stokholm, J. , Bartels, M. , Hottenga, J-J. , Heinrich, J. , Hewitt, J. , Keltikangas-Järvinen, L. , Korhonen, T. , Kaprio, J. , Lahti, J. , Lahti-Pulkkinen, M. , Lehtimäki, T. , Middeldorp, C. M. , Najman, J. M. , Pennell, C. , Power, C. , Oldehinkel, A. J. , Plomin, R. , Räikkönen, K. , Raitakari, O. T. , Rimfeld, K. , Sass, L. , Snieder, H. , Standl, M. , Sunyer, J. , Williams, G. M. , Bakermans-Kranenburg, M. J. , Boomsma, D. I. , van IJzendoorn, M. H. , Hartman, C. A. & Tiemeier, H. , 22-Aug-2022 , In: PLoS ONE. 17 , 8 , 23 p. , e0273116.

Research output: Contribution to journal › Article › Academic › peer-review

A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids

Ramdas, S., Judd, J., Graham, S. E., Kanoni, S., Wang, Y., Surakka, I., Wenz, B., Million Veterans Program, Clarke, S. L., Chesi, A., Wells, A., Bhatti, K. F., Vedantam, S., Winkler, T. W., Locke, A. E., Marouli, E., Zajac, G. J. M., Wu, K-H. H., Ntalla, I., Hui, Q., & 31 others Klarin, D. , Hilliard, A. T. , Wang, Z. , Xue, C. , Thorleifsson, G. , Helgadottir, A. , Gudbjartsson, D. F. , Holm, H. , Olafsson, I. , Hwang, M. Y. , Han, S. , Akiyama, M. , Zhao, W. , Zhao, J-H. , Le, P. , Verweij, N. , Benjamins, J. W. , Wang, Y. X. , van der Most, P. J. , van der Laan, S. W. , Wang, J-S. , Asselbergs, F. W. , Oldehinkel, A. J. , Snieder, H. , Penninx, B. , Kumari, M. , van der Harst, P. , Huang, W. , Kim, Y. J. , de Vries, P. S. & Zhu, X. , 4-Aug-2022 , In: American Journal of Human Genetics. 109 , 8 , p. 1366-1387 22 p.

Research output: Contribution to journal › Article › Academic › peer-review

A saturated map of common genetic variants associated with human height

23andMe Res Team, VA Million Vet Program, DiscovEHR DiscovEHR MyCode Communi, eEMERGE Elect Med Records Genomics, Lifelines Cohort Study, PRACTICAl Consortium, Understanding Soc Sci Grp, Yengo, L., Vedantam, S., Marouli, E., Sidorenko, J., Bartell, E., Sakaue, S., Graff, M., Eliasen, A. U., Jiang, Y., Raghavan, S., Miao, J., Arias, J. D., Graham, S. E., & 37 others Mukamel, R. E. , Spracklen, C. N. , Yin, X. , Chen, S-H. , Ferreira, T. , Highland, H. H. , Ji, Y. , Karaderi, T. , Lin, K. , Lull, K. , Malden, D. E. , Medina-Gomez, C. , Ani, A. , Demirkan, A. , Huang, J. , Kim, Y. J. , Le, P. , Nolte, I. M. , Raven, D. , Smith, A. , van der Laan, S. W. , van der Most, P. J. , Verweij, N. , Xie, T. , Zhao, J-H. , Zhao, W. , Asselbergs, F. W. , Hartman, C. A. , Huang, W. , Kumari, M. , Oldehinkel, A. J. , Penninx, B. W. J. H. , Rienstra, M. , Snieder, H. , van der Harst, P. , Wang, Y. X. & Visscher, P. M. , 12-Oct-2022 , (E-pub ahead of print) In: Nature. 610 , p. 704–712 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals

Lifelines Cohort Study, VA Million Veteran Program, DiscovEHR/MyCode , Winkler, T. W., Rasheed, H., Teumer, A., Gorski, M., Rowan, B. X., Stanzick, K. J., Thomas, L. F., Tin, A., Hoppmann, A., Chu, A. Y., Tayo, B., Thio, C. H. L. , Cusi, D., Chai, J-F., Sieber, K. B., Horn, K., Li, M., & 34 others Scholz, M. , Cocca, M. , Wuttke, M. , van der Most, P. J. , Yang, Q. , Ghasemi, S. , Nutile, T. , Li, Y. , Pontali, G. , Günther, F. , Dehghan, A. , Correa, A. , Parsa, A. , Feresin, A. , de Vries, A. P. J. , Zonderman, A. B. , Smith, A. V. , Oldehinkel, A. J. , De Grandi, A. , Rosenkranz, A. R. , Franke, A. , Teren, A. , Penninx, B. W. J. H. , Hartman, C. A. , Snieder, H. , Nolte, I. M. , de Borst, M. H. , Verweij, N. , van der Harst, P. , Gansevoort, R. T. , Bakker, S. J. L. , Huang, W. , Wang, Y. X. & Heid, I. M. , 13-Jun-2022 , In: Communications biology. 5 , 1 , 20 p. , 580.

Research output: Contribution to journal › Article › Academic › peer-review

Genetic Determinants of Serum Calcification Propensity and Cardiovascular Outcomes in the General Population

de Haan, A. , Ahmadizar, F. , van der Most, P. J. , Thio, C. H. L. , Kamali, Z. , Ani, A. , Ghanbari, M. , Chaker, L. , van Meurs, J. , Ikram, M. K. , van Goor, H. , Bakker, S. J. L. , van der Harst, P. , Snieder, H. , Kavousi, M. , Pasch, A. , Eijgelsheim, M. & de Borst, M. H. , 14-Jan-2022 , In: Frontiers in cardiovascular medicine. 8 , 11 p. , 809717.

Research output: Contribution to journal › Article › Academic › peer-review

Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies

Lifelines Cohort Study, Gorski, M., Rasheed, H., Teumer, A., Thomas, L. F., Graham, S. E., Sveinbjornsson, G., Winkler, T. W., Günther, F., Stark, K. J., Chai, J-F., Tayo, B. O., Wuttke, M., Li, Y., Tin, A., Ahluwalia, T. S., Ärnlöv, J., Åsvold, B. O., Bakker, S. J. L. , Banas, B., & 31 others Bansal, N. , Biggs, M. L. , Biino, G. , Böhnke, M. , Boerwinkle, E. , Bottinger, E. P. , Brenner, H. , Brumpton, B. , Carroll, R. J. , Chaker, L. , Chalmers, J. , Chee, M-L. , Chee, M-L. , Cheng, C-Y. , Chu, A. Y. , Ciullo, M. , Cocca, M. , Cook, J. P. , Coresh, J. , Cusi, D. , de Borst, M. H. , Degenhardt, F. , Eckardt, K-U. , Gansevoort, R. T. , Nolte, I. M. , Penninx, B. W. J. H. , Snieder, H. , Thio, C. H. L. , van der Harst, P. , van der Most, P. J. & Verweij, N. , Sept-2022 , In: Kidney International. 102 , 3 , p. 624-639 16 p.

Research output: Contribution to journal › Article › Academic › peer-review

Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention

Lifelines Cohort Study, Wang, Z., Emmerich, A., Pillon, N. J., Moore, T., Hemerich, D., Cornelis, M. C., Mazzaferro, E., Broos, S., Ahluwalia, T. S., Bartz, T. M., Bentley, A. R., Bielak, L. F., Chong, M., Chu, A. Y., Berry, D., Dorajoo, R., Dueker, N. D., Kasbohm, E., Feenstra, B., & 31 others Feitosa, M. F. , Gieger, C. , Graff, M. , Hall, L. M. , Haller, T. , Hartwig, F. P. , Hillis, D. A. , Huikari, V. , Heard-Costa, N. , Holzapfel, C. , Jackson, A. U. , Johansson, A. , Jorgensen, A. M. , Kaakinen, M. A. , Karlsson, R. , Kerr, K. F. , Kim, B. , Koolhaas, C. M. , Kutalik, Z. , Lagou, V. , Van der Most, P. J. , Van Vliet-Ostaptchouk, J. V. , Zhao, J-H. , Zhao, W. , Bruinenberg, M. , Hartman, C. A. , Nolte, I. M. , Smith, A. , Oldehinkel, A. J. , Penninx, B. W. J. H. & Snieder, H. , Sept-2022 , In: Nature genetics. 54 , 9 , p. 1332–1344 13 p.

Research output: Contribution to journal › Article › Academic › peer-review

Genome-Wide Association Meta-Analysis Identifies Novel Loci for Kidney Failure

van der Most, P. J. , Wang, S. , Guan, W. , Schladt, D. P. , Loza, B-L. , Caragh, S. , Heinzel, A. , Israni, A. K. , Jacobson, P. A. , Keating, B. , Conlon, P. J. , Oberbauer, R. , Snieder, H. & de Borst, M. , 3-May-2022 , In: Nephrology Dialysis Transplantation. 37 , Supplement 3 , p. I800-I801 2 p.

Research output: Contribution to journal › Meeting Abstract › Academic

Genome-wide association study and replication of liver enzyme loci

Lifelines Cohort Study, V A Million Veteran Program, Pazoki, R., Vujkovic, M., Elliott, J., Evangelou, E., Gill, D., Ghanbari, M., Van der Most, P. J. , Pinto, R. C., Wielscher, M., Farlik, M., Zuber, V., de Knegt, R. J., Snieder, H. , Uitterlinden, A. G., Lynch, J. A., Jiang, X., Said, S., Kaplan, D. E., & 17 others Lee, K. M. , Serper, M. , Carr, R. M. , Tsao, P. S. , Atkinson, S. R. , Dehghan, A. , Tzoulaki, I. , Ikram, A. , Herzig, K-H. , Jarvelin, M-R. , Alizadeh, B. Z. , O'Don-Nell, C. J. , Saleheen, D. , Voight, B. F. , Chang, K-M. , Thursz, M. R. & Elliott, P. , Apr-2022 , In: European Journal of Human Genetics. 30 , SUPPL 1 , p. 47-48 2 p.

Research output: Contribution to journal › Meeting Abstract › Academic

Identification and single-base gene-editing functional validation of a cis-EPO variant as a genetic predictor for EPO-increasing therapies

Harlow, C. E., Gandawijaya, J., Bamford, R. A., Martin, E. R., Wood, A. R., van der Most, P. J. , Tanaka, T., Leonard, H. L., Etheridge, A. S., Innocenti, F., Beaumont, R. N., Tyrrell, J., Nalls, M. A., Simonsick, E. M., Garimella, P. S., Shiroma, E. J., Verweij, N. , van der Meer, P. , Gansevoort, R. T. , Snieder, H. , & 13 others Gallins, P. J. , Jima, D. D. , Wright, F. , Zhou, Y. , Ferrucci, L. , Bandinelli, S. , Hernandez, D. G. , van der Harst, P. , Patel, V. V. , Waterworth, D. M. , Chu, A. Y. , Oguro-Ando, A. & Frayling, T. M. , 1-Sept-2022 , In: American Journal of Human Genetics. 109 , 9 , p. 1638-1652 15 p.

Research output: Contribution to journal › Article › Academic › peer-review

All (112) publications

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