dr. P.M. Schoonen

Faculty of Medical Sciences

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E-mail:

p.m.schoonen umcg.nl

Research Portal

Publications

Overexpression of Cyclin E1 or Cdc25A leads to replication stress, mitotic aberrancies, and increased sensitivity to replication checkpoint inhibitors

Kok, Y. P., Guerrero Llobet, S., Schoonen, P. M., Everts, M., Bhattacharya, A., Fehrmann, R. S. N., van den Tempel, N. & van Vugt, M. A. T. M., 7-Oct-2020, In: Oncogenesis. 9, 10, 15 p., 88.

Research output: Contribution to journal › Article › Academic › peer-review

Premature mitotic entry induced by ATR inhibition potentiates olaparib inhibition-mediated genomic instability, inflammatory signaling, and cytotoxicity in BRCA2-deficient cancer cells

Schoonen, P. M., Kok, Y. P., Wierenga, E., Bakker, B., Foijer, F., Spierings, D. C. J. & A T M van Vugt, M., 21-Oct-2019, In: Molecular oncology. 19 p.

Research output: Contribution to journal › Article › Academic › peer-review

Replication stress: Driver and therapeutic target in genomically instable cancers

Schoonen, P. M., Guerrero Llobet, S. & van Vugt, M. A. T. M., 2019, DNA Repair. Donev, R. (ed.). Elsevier, Vol. 115. p. 157-201 45 p. (Advances in protein chemistry and structural biology).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

Replication-stress induced mitotic aberrancies in cancer biology

Schoonen, P. M., 2019, [Groningen]: Rijksuniversiteit Groningen. 159 p.

Research output: Thesis › Thesis fully internal (DIV)

Never tear us a-PARP: Dealing with DNA lesions during mitosis

Schoonen, P. M. & van Vugt, M. A. T. M., 2018, In: Molecular & Cellular Oncology. 5, 1, 4 p., e1382670.

Research output: Contribution to journal › Article › Academic › peer-review

Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells

Schoonen, P. M., Talens, F., Stok, C., Gogola, E., Heijink, A. M., Bouwman, P., Foijer, F., Tarsounas, M., Blatter, S., Jonkers, J., Rottenberg, S. & van Vugt, M. A. T. M., 17-Jul-2017, In: Nature Communications. 8, 13 p., 15981.

Research output: Contribution to journal › Article › Academic › peer-review

All (9) publications

View full research profile

dr. P.M. Schoonen

Publications

Overexpression of Cyclin E1 or Cdc25A leads to replication stress, mitotic aberrancies, and increased sensitivity to replication checkpoint inhibitors

Premature mitotic entry induced by ATR inhibition potentiates olaparib inhibition-mediated genomic instability, inflammatory signaling, and cytotoxicity in BRCA2-deficient cancer cells

Replication stress: Driver and therapeutic target in genomically instable cancers

Replication-stress induced mitotic aberrancies in cancer biology

Never tear us a-PARP: Dealing with DNA lesions during mitosis

Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells

ATR inhibition preferentially targets homologous recombination-deficient tumor cells

p73 engages A2B receptor signalling to prime cancer cells to chemotherapy-induced death

Rif1 Is Required for Resolution of Ultrafine DNA Bridges in Anaphase to Ensure Genomic Stability