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How to find us dr. P.M. Schoonen
University Medical Center Groningen

dr. P.M. Schoonen

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E-mail:
p.m.schoonen umcg.nl
Publications

Publications

Overexpression of Cyclin E1 or Cdc25A leads to replication stress, mitotic aberrancies, and increased sensitivity to replication checkpoint inhibitors

Kok, Y. P. , Guerrero Llobet, S. , Schoonen, P. M. , Everts, M. , Bhattacharya, A. , Fehrmann, R. S. N. , van den Tempel, N. & van Vugt, M. A. T. M. , 7-Oct-2020 , In: Oncogenesis. 9 , 10 , 15 p. , 88.

Research output: Contribution to journal › Article › Academic › peer-review

Premature mitotic entry induced by ATR inhibition potentiates olaparib inhibition-mediated genomic instability, inflammatory signaling, and cytotoxicity in BRCA2-deficient cancer cells

Schoonen, P. M. , Kok, Y. P. , Wierenga, E. , Bakker, B. , Foijer, F. , Spierings, D. C. J. & A T M van Vugt, M. , 21-Oct-2019 , In: Molecular oncology. 19 p.

Research output: Contribution to journal › Article › Academic › peer-review

Replication stress: Driver and therapeutic target in genomically instable cancers

Schoonen, P. M. , Guerrero Llobet, S. & van Vugt, M. A. T. M. , 2019 , DNA Repair. Donev, R. (ed.). Elsevier , Vol. 115 . p. 157-201 45 p. (Advances in protein chemistry and structural biology).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

Replication-stress induced mitotic aberrancies in cancer biology

Schoonen, P. M. , 2019 , [Groningen]: Rijksuniversiteit Groningen . 159 p.

Research output: Thesis › Thesis fully internal (DIV)

Never tear us a-PARP: Dealing with DNA lesions during mitosis

Schoonen, P. M. & van Vugt, M. A. T. M. , 2018 , In: Molecular & Cellular Oncology. 5 , 1 , 4 p. , e1382670.

Research output: Contribution to journal › Article › Academic › peer-review

Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells

Schoonen, P. M. , Talens, F. , Stok, C. , Gogola, E., Heijink, A. M., Bouwman, P., Foijer, F. , Tarsounas, M., Blatter, S., Jonkers, J., Rottenberg, S. & van Vugt, M. A. T. M. , 17-Jul-2017 , In: Nature Communications. 8 , 13 p. , 15981.

Research output: Contribution to journal › Article › Academic › peer-review

ATR inhibition preferentially targets homologous recombination-deficient tumor cells

Krajewska, M., Fehrmann, R. S. N. , Schoonen, P. M. , Labib, S., de Vries, E. G. E. , Franke, L. & van Vugt, M. A. T. M. , Jun-2015 , In: ONCOGENE. 34 , 26 , p. 3474-3481 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

p73 engages A2B receptor signalling to prime cancer cells to chemotherapy-induced death

Long, J. S., Schoonen, P. M. , Graczyk, D., O'Prey, J. & Ryan, K. M., 1-Oct-2015 , In: ONCOGENE. 34 , 40 , p. 5152-5162 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

Rif1 Is Required for Resolution of Ultrafine DNA Bridges in Anaphase to Ensure Genomic Stability

Hengeveld, R. C. C., de Boer, H. R. , Schoonen, P. M. , de Vries, E. G. E. , Lens, S. M. A. & van Vugt, M. A. T. M. , 24-Aug-2015 , In: Developmental Cell. 34 , 4 , p. 466-474 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

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