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P.J. Colin

Universitair Hoofddocent

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Faculteit Medische Wetenschappen/UMCG

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E-mail:

p.j.colin umcg.nl

ORCID Research Portal

Publicaties

Evaluating Model‐Based Extrapolation of Plasma Exposure for Long‐Acting Injectable Products: From Single‐ to Multiple‐Dose Trials

Lubberts, D. E., Eleveld, D. J., Verscheijden, L. F. M., Colin, P. J. & Koomen, J. V., feb.-2026, In: CPT: Pharmacometrics & Systems Pharmacology. 15, 2, 9 blz., e70170.

Onderzoeksoutput › › peer review

A Population Pharmacokinetic Analysis for Piperacillin/Tazobactam in Patients with End-Stage Kidney Disease Undergoing Intermittent Haemodialysis: Extension of a General-Purpose Model

Kong, D., Koomen, J. V., Vanommeslaeghe, F., Delanghe, S., Van Biesen, W., Colin, P. J. & Eloot, S., aug.-2025, In: Clinical Pharmacokinetics. 64, 14 blz., e0157923.

Onderzoeksoutput › › peer review

A review on the role of extrapolation as basis for paediatric marketing authorization applications of medicines in the EU

Simons, C. W. M., Maton, L. C. H., van Dartel, M., van den Heuvel, M., den Otter, L., Versantvoort, C., Colin, P. J. & Koomen, J. V., 2025, In: British Journal of Clinical Pharmacology. 91, 5, blz. 1500-1510 11 blz.

Onderzoeksoutput › › peer review

Current Use of Physiologically Based Pharmacokinetic modeling in New Medicinal Product Approvals at EMA

Paul, P., Colin, P. J., Musuamba Tshinanu, F., Versantvoort, C., Manolis, E. & Blake, K., mrt.-2025, In: Clinical Pharmacology and Therapeutics. 117, 3, blz. 808-817 10 blz.

Onderzoeksoutput › › peer review

Development and analysis of a remimazolam pharmacokinetics and pharmacodynamics model with proposed dosing and concentrations for anaesthesia and sedation

Eleveld, D. J., Colin, P. J., Van den Berg, J. P., Koomen, J. V., Stoehr, T. & Struys, M. M. R. F., jul.-2025, In: British Journal of Anaesthesia. 135, 1, blz. 206-217 12 blz.

Onderzoeksoutput › › peer review

Influence of remifentanil on the pharmacokinetics and pharmacodynamics of remimazolam in healthy volunteers

Vellinga, R., Koomen, J. V., Eleveld, D. J., Stöhr, T., Pesic, M., Struys, M. M. R. F. & Colin, P., apr.-2025, In: Anesthesiology. 142, 4, blz. 666-679 14 blz.

Onderzoeksoutput › › peer review

Pharmacokinetics and pharmacodynamics of remimazolam for procedural sedation in children and adolescents

Colin, P. J., Bichajian, L. H., Curt, V. R., Koomen, J. V., Stöhr, T., Struys, M. M. R. F. & Mason, K. P., aug.-2025, In: Anesthesiology. 143, 2, blz. 368-382 15 blz.

Onderzoeksoutput › › peer review

Reply to: “Current Use of PBPK Modeling in New Medicinal Product Approvals at EMA: A Clinical Appraisal of Voclosporin in Lupus Nephritis”

Paul, P., Colin, P. J., Musuamba Tshinanu, F., Versantvoort, C., Manolis, E. & Blake, K., sep.-2025, In: Clinical Pharmacology and Therapeutics. 118, 3, blz. 544 1 blz.

Onderzoeksoutput: Comment/Letter to the editor › › peer review

The dose-response relationship between norepinephrine dose and mean arterial pressure with and without general anaesthesia: A study in healthy volunteers

de Keijzer, I. N., van den Berg, J. P., Massari, D., Absalom, A. R., Bosch, D. J., van Faassen, M., Scheeren, T. W. L., Struys, M. M. R. F., Colin, P. J. & Vos, J. J., 21-nov.-2025, (E-pub ahead of print) In: European journal of anaesthesiology.

Onderzoeksoutput › › peer review

The dose-response relationship between norepinephrine dose and mean arterial pressure with and without general anaesthesia: A study in healthy volunteers

de Keijzer, I. N., van den Berg, J. P., Massari, D., Absalom, A. R., Bosch, D. J., van Faassen, M., Scheeren, T. W. L., Struys, M. M. R. F., Colin, P. J. & Vos, J. J., 21-nov.-2025, In: European journal of anaesthesiology. Publish Ahead of Print, 10.1097/EJA.0000000000002312.

Onderzoeksoutput › › peer review

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