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Over ons Praktische zaken Waar vindt u ons P.J. Colin

Publicaties

A review on the role of extrapolation as basis for paediatric marketing authorization applications of medicines in the EU

Current Use of Physiologically Based Pharmacokinetic modeling in New Medicinal Product Approvals at EMA

Development and analysis of a remimazolam pharmacokinetics and pharmacodynamics model with proposed dosing and concentrations for anaesthesia and sedation

Influence of remifentanil on the pharmacokinetics and pharmacodynamics of remimazolam in healthy volunteers

A Pooled Pharmacokinetic Analysis for Piperacillin/Tazobactam Across Different Patient Populations: From Premature Infants to the Elderly

EMA perspective on the value of model-informed drug development for labeling recommendations regarding medicine use during pregnancy and breastfeeding

Population Pharmacokinetic Modelling of Norepinephrine in Healthy Volunteers Prior to and During General Anesthesia

Target-controlled Infusion of Remimazolam in Healthy Volunteers Shows Some Acute Tolerance

A Joint Pharmacokinetic Model for the Simultaneous Description of Plasma and Whole Blood Tacrolimus Concentrations in Kidney and Lung Transplant Recipients

Development of a pharmacokinetic and pharmacodynamic model for intranasal administration of midazolam in older adults: a single-site two-period crossover study