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P.E. Ettema

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Faculteit Science and Engineering

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Publicaties

Development of Indole-3-yl-methylene-thiobarbital Derivatives as Inhibitors of HDAC8 Enzyme Activity

Elsayed, A. A. F., Zhang, J., Shalas, A. F., van der Wouden, P. E., van Pinxteren, D. J. M., Jespers, W. & Dekker, F. J., 23-jul-2026, In: Journal of Medicinal Chemistry. 69, 14, blz. 16381-16400 20 blz.

Onderzoeksoutput › › peer review

Correction to “Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione Derivative Inhibits d-Dopachrome Tautomerase Activity and Suppresses the Proliferation of Non-Small Cell Lung Cancer Cells”Article link copied!

Xiao, Z., Osipyan, A., Song, S., Chen, D., Schut, R. A., van Merkerk, R., van der Wouden, P. E., Cool, R. H., Quax, W. J., Melgert, B. N., Poelarends, G. J. & Dekker, F. J., 27-mrt-2025, In: Journal of Medicinal Chemistry. 68, 6, blz. 6844-6845 2 blz.

Onderzoeksoutput

Novel 15-lipoxygenase-1 inhibitor protects cells from RSL3-induced cell death

Zhang, J., van der Wouden, P. E. & Dekker, F. J., 5-jun-2025, In: European Journal of Medicinal Chemistry. 290, 11 blz., 117517.

Onderzoeksoutput › › peer review

Small Molecule MIF Modulation Enhances Ferroptosis by Impairing DNA Repair Mechanisms

Chen, D., Zhao, C., Zhang, J., Knol, C. W. J., Osipyan, A., Majerníková, N., Chen, T., Xiao, Z., Adriana, J., Griffith, A. J., Soto-Gamez, A., van der Wouden, P. E., Coppes, R. P., Dolga, A. M., Haisma, H. J. & Dekker, F. J., 27-aug-2024, In: Advanced science . 11, 32, 15 blz., e2403963.

Onderzoeksoutput › › peer review

The synthesis of 1,2,3-triazoles as binders of D-dopachrome tautomerase (D-DT) for the development of dual-targeting inhibitors

Osipyan, A., Bulai, R. G., Wu, Z., de Witte, J., van der Velde, J. J. H., Kader, M., van der Wouden, P. E., Poelarends, G. J. & Dekker, F. J., 5-okt-2024, In: European Journal of Medicinal Chemistry. 276, 116665.

Onderzoeksoutput › › peer review

Allosteric Inhibitors of Macrophage Migration Inhibitory Factor (MIF) Interfere with Apoptosis-Inducing Factor (AIF) Co-Localization to Prevent Parthanatos

Chen, D., Osipyan, A., Adriana, J., Kader, M., Gureev, M., Knol, C. W. J., Sigmund, M. C., Xiao, Z., van der Wouden, P. E., Cool, R. H., Poelarends, G. J. & Dekker, F. J., 13-jul-2023, In: Journal of Medicinal Chemistry. 66, 13, blz. 8767-8781 15 blz.

Onderzoeksoutput › › peer review

Histone Deacetylase 3-Directed PROTACs Have Anti-inflammatory Potential by Blocking Polarization of M0-like into M1-like Macrophages

Zhao, C., Chen, S., Chen, D., Río-Bergé, C., Zhang, J., Ettema, P., Daemen, T. & Dekker, F. J., 16-okt-2023, In: Angewandte Chemie (International ed. in English). 62, 42, 11 blz., e202310059.

Onderzoeksoutput › › peer review

Protocol of the Double-Click Seq Method to Evaluate the Deposition Bias of Chromatin Proteins

van der Wouden, P. E., Zwinderman, M. R. H., Chen, D., Borghesan, M. & Dekker, F. J., jun-2023, In: Current Protocols. 3, 6, 17 blz., e805.

Onderzoeksoutput › › peer review

4-Iodopyrimidine labeling reveals nuclear translocation and nuclease activity for both MIF and MIF2

Xiao, Z., Chen, D., Mulder, F., Song, S., van der Wouden, P. E., Cool, R. H., Melgert, B. N., Poelarends, G. J. & Dekker, F. J., 3-jan-2022, In: Chemistry. 28, 1, e202103030.

Onderzoeksoutput › › peer review

Thieno[2,3- d]pyrimidine-2,4(1 H,3 H)-dione Derivative Inhibits d -Dopachrome Tautomerase Activity and Suppresses the Proliferation of Non-Small Cell Lung Cancer Cells

Xiao, Z., Osipyan, A., Song, S., Chen, D., Schut, R. A., van Merkerk, R., van der Wouden, P. E., Cool, R. H., Quax, W. J., Melgert, B. N., Poelarends, G. J. & Dekker, F. J., 10-feb-2022, In: Journal of Medicinal Chemistry. 65, 3, blz. 2059-2077

Onderzoeksoutput › › peer review

Alle (27) publicaties

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