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P.E. Ettema

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Faculty of Science and Engineering

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+31 50 36 33064

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Research Portal

Publications

Allosteric Inhibitors of Macrophage Migration Inhibitory Factor (MIF) Interfere with Apoptosis-Inducing Factor (AIF) Co-Localization to Prevent Parthanatos

Chen, D., Osipyan, A., Adriana, J., Kader, M., Gureev, M., Knol, C. W. J., Sigmund, M. C., Xiao, Z., van der Wouden, P. E., Cool, R. H., Poelarends, G. J. & Dekker, F. J., 13-Jul-2023, In: Journal of Medicinal Chemistry. 66, 13, p. 8767-8781 15 p.

Research output: Contribution to journal › Article › Academic › peer-review

Histone Deacetylase 3-Directed PROTACs Have Anti-inflammatory Potential by Blocking Polarization of M0-like into M1-like Macrophages

Zhao, C., Chen, S., Chen, D., Río-Bergé, C., Zhang, J., Ettema, P., Daemen, T. & Dekker, F. J., 16-Oct-2023, In: Angewandte Chemie (International ed. in English). 62, 42, 11 p., e202310059.

Research output: Contribution to journal › Article › Academic › peer-review

Protocol of the Double-Click Seq Method to Evaluate the Deposition Bias of Chromatin Proteins

van der Wouden, P. E., Zwinderman, M. R. H., Chen, D., Borghesan, M. & Dekker, F. J., Jun-2023, In: Current Protocols. 3, 6, 17 p., e805.

Research output: Contribution to journal › Article › Academic › peer-review

4-Iodopyrimidine labeling reveals nuclear translocation and nuclease activity for both MIF and MIF2

Xiao, Z., Chen, D., Mulder, F., Song, S., van der Wouden, P. E., Cool, R. H., Melgert, B. N., Poelarends, G. J. & Dekker, F. J., 3-Jan-2022, In: Chemistry. 28, 1, e202103030.

Research output: Contribution to journal › Article › Academic › peer-review

Thieno[2,3- d]pyrimidine-2,4(1 H,3 H)-dione Derivative Inhibits d -Dopachrome Tautomerase Activity and Suppresses the Proliferation of Non-Small Cell Lung Cancer Cells

Xiao, Z., Osipyan, A., Song, S., Chen, D., Schut, R. A., van Merkerk, R., van der Wouden, P. E., Cool, R. H., Quax, W. J., Melgert, B. N., Poelarends, G. J. & Dekker, F. J., 10-Feb-2022, In: Journal of Medicinal Chemistry. 65, 3, p. 2059-2077

Research output: Contribution to journal › Article › Academic › peer-review

Deposition Bias of Chromatin Proteins Inverts under DNA Replication Stress Conditions

Zwinderman, M. R. H., Lobo, T. J., van der Wouden, P. E., Spierings, D. C. J., van Vugt, M. A. T. M., Lansdorp, P. M., Guryev, V. & Dekker, F. J., 19-Nov-2021, In: ACS chemical biology. 16, 11, p. 2193-2201 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

Identification of a Bromodomain-like region in 15-Lipoxygenase-1 explains its Nuclear Localization

Chen, D., Xiao, Z., Guo, H., Gogishvili, D., Setroikromo, R., van der Wouden, P. E. & Dekker, F. J., 27-Sept-2021, In: Angewandte Chemie (International ed. in English). 60, 40, p. 21875-21883 21875 p.

Research output: Contribution to journal › Article › Academic › peer-review

Proteolysis Targeting Chimera (PROTAC) for Macrophage Migration Inhibitory Factor (MIF) Has Anti-Proliferative Activity in Lung Cancer Cells

Xiao, Z., Song, S., Chen, D., van Merkerk, R., van der Wouden, P., Cool, R., Quax, W., Poelarends, G., Melgert, B. & Dekker, F. J., 2-Aug-2021, In: Angewandte Chemie (International ed. in English). 60, 32, p. 17514-17521 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

7-Hydroxycoumarins are Affinity-based Fluorescent Probes for Competitive Binding Studies of Macrophage Migration Inhibitory Factor

Xiao, Z., Chen, D., Song, S., van der Vlag, R., van der Wouden, P. E., van Merkerk, R., Cool, R., Hirsch, A. K. H., Melgert, B., Quax, W. J., Poelarends, G. J. & Dekker, F. J., 22-Oct-2020, In: Journal of Medicinal Chemistry. 63, 20, p. 11920-11933 14 p.

Research output: Contribution to journal › Article › Academic › peer-review

Induced protein degradation of histone deacetylases 3 (HDAC3) by proteolysis targeting chimera (PROTAC)

Cao, F., de Weerd, S., Chen, D., Zwinderman, M. R. H., van der Wouden, P. E. & Dekker, F. J., 15-Dec-2020, In: European Journal of Medicinal Chemistry. 208, 112800.

Research output: Contribution to journal › Article › Academic › peer-review

All (22) publications

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