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Over ons Praktische zaken Waar vindt u ons N. (Nieske) Brouwer

Publicaties

Radiotherapy induces persistent innate immune reprogramming of microglia into a primed state

APOE4 impairs the microglial response in Alzheimer’s disease by inducing TGFβ-mediated checkpoints

Characterizing microglial gene expression in a model of secondary progressive multiple sclerosis

Brain macrophages acquire distinct transcriptomes in multiple sclerosis lesions and normal appearing white matter

Distinct gene expression in demyelinated white and grey matter areas of patients with multiple sclerosis

Early-life stress lastingly impacts microglial transcriptome and function under basal and immune-challenged conditions

Epigenetic regulation of innate immune memory in microglia

Neurovascular dysfunction in GRN-associated frontotemporal dementia identified by single-nucleus RNA sequencing of human cerebral cortex

Distinct amyloid-beta and tau-associated microglia profiles in Alzheimer's disease

Human fetal microglia acquire homeostatic immune-sensing properties early in development

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