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Over ons Praktische zaken Waar vindt u ons prof. dr. N.C. van de Merbel

prof. dr. N.C. van de Merbel

Bijzonder hoogleraar industriele bioanalyse

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Faculteit Science and Engineering

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n.c.van.de.merbel rug.nl

Research Portal

Publicaties

Simultaneous quantification of the 22-kDa isoforms of human growth hormone 1 and 2 in human plasma by multiplexed immunocapture and LC-MS/MS

Sleumer, B., van Faassen, M., Vos, M. J., den Besten, G., Kema, I. P. & van de Merbel, N. C., 1-feb.-2024, In: Clinica chimica acta. 554, 9 blz., 117736.

Onderzoeksoutput › › peer review

An antibody-free LC-MS/MS method for the quantification of sex hormone binding globulin in human serum and plasma

Sleumer, B., Zwerwer, J., Van Faassen, M., Vos, M. J., Bischoff, R., Kema, I. P. & Van De Merbel, N. C., 2023, In: Clinical chemistry and laboratory medicine. 61, 7, blz. 1266–1274 9 blz.

Onderzoeksoutput › › peer review

A Quantitative LC-MS/MS Method for Distinguishing the Tau Protein Forms Phosphorylated and Nonphosphorylated at Serine-396

Jacobsen, A-M., van de Merbel, N. C., Ditlevsen, D. K., Tvermosegaard, K., Schalk, F., Lambert, W., Bundgaard, C., Pedersen, J. T. & Rosenqvist, N., 1-mrt.-2023, In: Journal of the American Society for Mass Spectrometry. 34, 3, blz. 441-451 11 blz.

Onderzoeksoutput › › peer review

Biotransformation of Trastuzumab and Pertuzumab in Breast Cancer Patients assessed by Affinity Enrichment and Ion Exchange Chromatography

Olaleye, O., Spanov, B., Bults, P., Voort, A. V. D., Govorukhina, N., Sonke, G. S., Horvatovich, P., van de Merbel, N. C. & Bischoff, R., feb.-2023, In: Drug Metabolism and Disposition. 50, 12, blz. 249-256 8 blz.

Onderzoeksoutput › › peer review

Determination of Binding Sites on Trastuzumab and Pertuzumab to Selective Affimers Using Hydrogen-Deuterium Exchange Mass Spectrometry

Olaleye, O., Graf, C., Spanov, B., Govorukhina, N., Groves, M. R., van de Merbel, N. C. & Bischoff, R., 5-apr.-2023, In: Journal of the American Society for Mass Spectrometry. 34, 4, blz. 775-783 9 blz.

Onderzoeksoutput › › peer review

Immunocapture LC-MS(/MS) assays for biotherapeutic and biomarker proteins: the European Bioanalysis Forum continuing discussions on scientific and regulatory challenges

Barfield, M., Blackburn, M., Blattmann, P., Ingelse, B., Jordan, G., Fusetti, F., Gnoth, M. J., Sporring, S. H., Love, I., Muccio, S., de Merbel, N. V., Wheller, R., Wilson, A. & Timmerman, P., mei-2023, In: Bioanalysis. 15, 9, blz. 477-480 4 blz.

Onderzoeksoutput ›

Pertuzumab Charge Variant Analysis and Complementarity-Determining Region Stability Assessment to Deamidation

Spanov, B., Olaleye, O., Mesurado, T., Govorukhina, N., Jungbauer, A., van de Merbel, N. C., Lingg, N. & Bischoff, R., 28-feb.-2023, In: Analytical Chemistry. 95, 8, blz. 3951-3958 8 blz.

Onderzoeksoutput › › peer review

Quantitative bioanalysis of proteins by digestion and LC-MS/MS: the use of multiple signature peptides

Sleumer, B., Kema, I. P. & van de Merbel, N. C., okt.-2023, In: Bioanalysis. 15, 19, blz. 1203-1216 14 blz.

Onderzoeksoutput › peer review

Revealing charge heterogeneity of stressed trastuzumab at the subunit level

Spanov, B., Baartmans, B., Olaleye, O., Nicolardi, S., Govorukhina, N., Wuhrer, M., van de Merbel, N. C. & Bischoff, R., mrt.-2023, In: Analytical and Bioanalytical Chemistry. 415, 8, blz. 1505-1513 9 blz.

Onderzoeksoutput › › peer review

Analytical and pharmacological consequences of the in vivo deamidation of trastuzumab and pertuzumab

Bults, P., van der Voort, A., Meijer, C., Sonke, G. S., Bischoff, R. & van de Merbel, N. C., feb.-2022, In: Analytical and Bioanalytical Chemistry. 414, 4, blz. 1513–1524 11 blz.

Onderzoeksoutput › › peer review

Alle (71) publicaties

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