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Publicaties

Energetic stress in combination with impaired fatty acid oxidation induces sequestration of CoA and adaptation of CoA metabolism

Dysregulation of Glial Gap Junction Protein Innexin2 Mediates Seizures and Disrupted Sleep in a Drosophila Model for North Sea Progressive Myoclonus Epilepsy

Opt1 imports CoA precursors as glutathione mixed disulphides

Coenzyme A precursors flow from mother to zygote and from microbiome to host

The Coenzyme A Level Modulator Hopantenate (HoPan) Inhibits Phosphopantotenoylcysteine Synthetase Activity

Vps13 is required for timely removal of nurse cell corpses

4 '-Phosphopantetheine corrects CoA, iron, and dopamine metabolic defects in mammalian models of PKAN

CoA-dependent activation of mitochondrial acyl carrier protein links four neurodegenerative diseases

Human VPS13A is associated with multiple organelles and influences mitochondrial morphology and lipid droplet motility

Acetyl-4'-phosphopantetheine is stable in serum and prevents phenotypes induced by pantothenate kinase deficiency