prof. dr. M. (Michiel) Rienstra

prof. dr. M. (Michiel) Rienstra
Telephone:
+31 50 361 2355 ((secretariaat))
+31 50 361 2878 ((direct))
E-mail:
m.rienstra umcg.nl

Research

Research interests

Graduated in medicine at the University of Antwerp, Belgium in 2003. Obtained a PhD at the University of Groningen, The Netherlands in 2007 on Atrial Fibrillation, Underlying Disease and Prognosis. I completed my cardiology training at the University Medical Center Groningen in 2012, where continued working as clinical cardiologist and researcher. I was awarded with a NWO Rubicon grant in 2009 and went to Harvard Medical School, Massachusetts General Hospital and the Framingham Heart Study for a post-doc on population genetics and epidemiology in 2010-2011. In 2012 I was awarded with the NWO Veni grant for his project on genetics of atrial fibrillation. In 2015 I received the European Society of Cardiology academic grant for his project on a big data approach in atrial fibrillation. I am work package leader of 4 large national consortia; RACE V (hypercoagulability and AF progression), RED-CVD (early detection of cardiovascular disease in general practices), AI (catalyzing the application of artificial intelligence in CV disease), and MyDigiTwin (Big-data and Artificial Intelligence-based ecosystem to create a user’s personal “Digital Twin”). I am steering committee member of several investigator-initiated clinical studies (RACE 2 to 7, MARC 1-2, VIP-HF, DECISION). I am fellow of the European Society of Cardiology and the American Heart Association, and Scientific & Clinical Education Lifelong Learning Committee (SCILL) member of the AHA - Genomics and Precision Medicine council.

 

I combine clinical cardiology focusing on treatment of patients with arrhythmias, with clinical-oriented research. My research consists of conducting clinical studies to improve AF treatment, studying epidemiology of AF and its risk factors in PREVEND, Lifelines and Framingham Heart Study, uncovering the genetics of atrial fibrillation in part with the international AFGen onsortium, and applying novel bioinformatics tools to improve AF risk prediction.

Publications
  1. What should the C ("Congestive heart failure") represent in the CHA2 DS2 -VASc score?

    Mulder, B. A., van Veldhuisen, D. J. & Rienstra, M., 27-Jun-2020, In : European Journal of Heart Failure.

    Research output: Contribution to journalArticleAcademicpeer-review

  2. Circulating plasma concentrations of angiotensin-converting enzyme 2 in men and women with heart failure and effects of renin-angiotensin-aldosterone inhibitors

    Sama, I. E., Ravera, A., Santema, B. T., van Goor, H., Ter Maaten, J. M., Cleland, J. G. F., Rienstra, M., Friedrich, A. W., Samani, N. J., Ng, L. L., Dickstein, K., Lang, C. C., Filippatos, G., Anker, S. D., Ponikowski, P., Metra, M., van Veldhuisen, D. J. & Voors, A. A., 14-May-2020, In : European Heart Journal. 41, 19, p. 1810-1817 8 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  3. Atrial fibrillation in chronic heart failure patients with reduced ejection fraction: The CHECK-HF registry

    CHECK-HF Investigators, Veenis, J. F., Brunner-La Rocca, H-P., Linssen, G. C. M., Smeele, F. J. J., Wouters, N. T. A. E., Westendorp, P. H. M., Rademaker, P. C., Hemels, M. E. W., Rienstra, M., Hoes, A. W. & Brugts, J. J., 1-Jun-2020, In : International Journal of Cardiology. 308, p. 60-66 7 p.

    Research output: Contribution to journalArticleAcademicpeer-review

  4. Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

    Ntalla, I., Weng, L-C., Cartwright, J. H., Hall, A. W., Sveinbjornsson, G., Tucker, N. R., Choi, S. H., Chaffin, M. D., Roselli, C., Barnes, M. R., Mifsud, B., Warren, H. R., Hayward, C., Marten, J., Cranley, J. J., Concas, M. P., Gasparini, P., Boutin, T., Kolcic, I., Polasek, O., Rudan, I., Araujo, N. M., Lima-Costa, M. F., Ribeiro, A. L. P., Souza, R. P., Tarazona-Santos, E., Giedraitis, V., Ingelsson, E., Mahajan, A., Morris, A. P., Del Greco M, F., Foco, L., Gögele, M., Hicks, A. A., Cook, J. P., Lind, L., Lindgren, C. M., Sundström, J., Nelson, C. P., Riaz, M. B., Samani, N. J., Sinagra, G., Ulivi, S., Kähönen, M., Mishra, P. P., Mononen, N., Nikus, K., Caulfield, M. J., Dominiczak, A., Padmanabhan, S., Montasser, M. E., O'Connell, J. R., Ryan, K., Shuldiner, A. R., Aeschbacher, S., Conen, D., Risch, L., Thériault, S., Hutri-Kähönen, N., Lehtimäki, T., Lyytikäinen, L-P., Raitakari, O. T., Barnes, C. L. K., Campbell, H., Joshi, P. K., Wilson, J. F., Isaacs, A., Kors, J. A., van Duijn, C. M., Huang, P. L., Gudnason, V., Harris, T. B., Launer, L. J., Smith, A. V., Bottinger, E. P., Loos, R. J. F., Nadkarni, G. N., Preuss, M. H., Correa, A., Mei, H., Wilson, J., Meitinger, T., Müller-Nurasyid, M., Peters, A., Waldenberger, M., Mangino, M., Spector, T. D., Rienstra, M., van de Vegte, Y. J., van der Harst, P., Verweij, N., Kääb, S., Schramm, K., Sinner, M. F., Strauch, K., Cutler, M. J., Fatkin, D., London, B., Olesen, M., Roden, D. M., Benjamin Shoemaker, M., Gustav Smith, J., Biggs, M. L., Bis, J. C., Brody, J. A., Psaty, B. M., Rice, K., Sotoodehnia, N., De Grandi, A., Fuchsberger, C., Pattaro, C., Pramstaller, P. P., Ford, I., Wouter Jukema, J., Macfarlane, P. W., Trompet, S., Dörr, M., Felix, S. B., Völker, U., Weiss, S., Havulinna, A. S., Jula, A., Sääksjärvi, K., Salomaa, V., Guo, X., Heckbert, S. R., Lin, H. J., Rotter, J. I., Taylor, K. D., Yao, J., de Mutsert, R., Maan, A. C., Mook-Kanamori, D. O., Noordam, R., Cucca, F., Ding, J., Lakatta, E. G., Qian, Y., Tarasov, K. V., Levy, D., Lin, H., Newton-Cheh, C. H., Lunetta, K. L., Murray, A. D., Porteous, D. J., Smith, B. H., Stricker, B. H., Uitterlinden, A., van den Berg, M. E., Haessler, J., Jackson, R. D., Kooperberg, C., Peters, U., Reiner, A. P., Whitsel, E. A., Alonso, A., Arking, D. E., Boerwinkle, E., Ehret, G. B., Soliman, E. Z., Avery, C. L., Gogarten, S. M., Kerr, K. F., Laurie, C. C., Seyerle, A. A., Stilp, A., Assa, S., Abdullah Said, M., Yldau van der Ende, M., Lambiase, P. D., Orini, M., Ramirez, J., Van Duijvenboden, S., Arnar, D. O., Gudbjartsson, D. F., Holm, H., Sulem, P., Thorleifsson, G., Thorolfsdottir, R. B., Thorsteinsdottir, U., Benjamin, E. J., Tinker, A., Stefansson, K., Ellinor, P. T., Jamshidi, Y., Lubitz, S. A. & Munroe, P. B., 21-May-2020, In : Nature Communications. 11, 1, 12 p., 2542.

    Research output: Contribution to journalArticleAcademicpeer-review

  5. Complex clinical scenarios with the use of direct oral anticoagulants in patients with atrial fibrillation: a multidisciplinary expert advisory board

    Mulder, B. A., Ten Berg, J., Ten Cate, H., van Es, N., Hemels, M. E. W., Kappelle, L. J., Bearda Bakker, H. B., de Borst, G. J., Drenth, D. J., Geersing, G. J. & Rienstra, M., 11-May-2020, In : Netherlands Heart Hournal. 8 p.

    Research output: Contribution to journalReview articleAcademicpeer-review

View all (189) »

Press / Media
  1. CONNECT magazine

    Michiel Rienstra & RG Tieleman

    28/02/2020

    1 Media contribution

    Press/Media: Public Engagement ActivitiesProfessional

  2. Ik vertrouw op mijn collega's in de regionale ziekenhuizen

    Michiel Rienstra

    20/02/2020

    1 Media contribution

    Press/Media: Public Engagement ActivitiesProfessional

  3. Dagblad van het Noorden interview; ‘Samen voor het hart‘

    Michiel Rienstra

    20/04/2019

    1 Media contribution

    Press/Media: Public Engagement ActivitiesPopular

View all (4) »

Activities
  1. Co-investigator HARMONY randomized trial (External organisation)

    Michiel Rienstra (Member)
    20172018

    Activity: MembershipMembership of committeeAcademic

  2. Center - principal investigator MONITOR-HF trial (External organisation)

    Michiel Rienstra (Member)
    2019 → …

    Activity: MembershipMembership of committeeAcademic

  3. Steering committee of the APAF-CRT randomized trial (External organisation)

    Michiel Rienstra (Member)
    2019 → …

    Activity: MembershipMembership of committeeAcademic

View all (6) »

Prizes
  1. ESC - Stroke Council award

    Michiel Rienstra (Recipient), 2019

    Prize: Fellowship awarded competitivelyAcademic

View all (2) »

ID: 14822694