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Over ons Praktische zaken Waar vindt u ons prof. dr. M.N. (Marjolijn) Lub-de Hooge
University Medical Center Groningen

prof. dr. M.N. (Marjolijn) Lub-de Hooge

Ziekenhuisapotheker, hoogleraar ziekenhuisfarmacie
Research interests Publicaties Pers/media

Research interests

Prof. Dr. Marjolijn N. Lub-de Hooge

is a Hospital Pharmacist and professor at the department of Clinical Pharmacy and Pharmacology, and at the department of Nuclear Medicine and Molecular Imaging of the University Medical Center Groningen. She obtained her PhD on pharmaceutical aspects and molecular imaging of new receptor targeted drugs.

Her research mainly focuses on molecular imaging to support drug development and to optimize treatment of cancer patients with novel (targeted and immuno) therapies. She is an expert in the development, evaluation and translation of new radiopharmaceuticals and optical tracers to the clinical setting. And she is also involved in the subsequent clinical application of these new tracers for drug development, and treatment optimization: visualization of presence of drug target (patient selection), drug biodistribution (pharmacokinetics, optimal dosing, target saturation) and tumor status during treatment (early predictive biomarker, pharmacodynamics).

 

 

Publicaties

Author Correction: Whole-body CD8 + T-cell PET imaging in patients with large B-cell lymphoma before and during CD19-directed CAR T-cell therapy: a phase 2 study.

de Boer, J. W., Keijzer, K., van Doesum, J. A., Smit, N. A. M., Brouwers, A. H., van Sluis, J., Lub-de Hooge, M. N., Pierik, F. R., Huls, G. A., van Dijk, L. V., Visser, L., Diepstra, A., Noordzij, W., Williams, S. P., Ungewickell, A., Elias, S. G., de Vries, E. G. E., Niezink, A. G. H. & van Meerten, T., 10-feb.-2026, In: Nature Communications. 17, 1, blz. 1499

Onderzoeksoutput: Article › › peer review

Delayed [89Zr]Zr-N-Succinyldesferal-Trastuzumab Imaging Enabled by Long-Axial-Field-of-View PET/CT.

Mohr, P., Li, Z., van Sluis, J., Lub-de Hooge, M. N., van den Brom, R. R. H., Lammertsma, A. A., Tsoumpas, C. & Brouwers, A. H., jan.-2026, In: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 67, 1, blz. 160-161 2 blz.

Onderzoeksoutput: Article › › peer review

Pharmacological boosting of azacitidine/venetoclax in acute myeloid leukemia

Westra, N., Cerro, E. R., Schilder, E., Lub-deHooge, M., Touw, D. J., Kosterink, J. G., Chitu, D. A., Ammatuna, E., Klein, S. K., Westerweel, P. E., Cuijpers, M., Cruijsen, M. J., Corsten, M. M., Alhan, C., Tick, L., Schuringa, J. J., Huls, G., Woolthuis, C. M. & Munnink, T. H. O., mrt.-2026, In: Blood Neoplasia.

Onderzoeksoutput: Article › › peer review

Roadmap for the accelerated development and clinical translation of fluorescent tracers: Adalimumab-680LT as a proof of concept

Huizinga, H. K., van Dijken, R. J., Gareb, B., Dekkers, B. G. J., van Zanten, J., Westra, H. H., Koopmans, P., Nagengast, W. B. & Lub-de Hooge, M. N., jun.-2026, In: International Journal of Pharmaceutics: X. 11

Onderzoeksoutput: Article › › peer review

Development of Clinical-Grade Durvalumab-680LT and Nivolumab-800CW for Multispectral Fluorescent Imaging of the PD-1/PD-L1 Axis of the Immune Checkpoint Pathway

Huizinga, H. K., Hooghiemstra, W. T. R., Linssen, M. D., Allersma, D. P., Gareb, B., Dekkers, B. G. J., Nagengast, W. B. & Hooge, M. N.L.-D., 7-okt.-2025, In: Pharmaceuticals. 18, 10, 18 blz., 1501.

Onderzoeksoutput: Article › › peer review

Extemporaneous Compounding, Pharmacy Preparations and Related Product Care in the Netherlands

Woerdenbag, H. J., van Basten, B., Oussoren, C., Smeets, O. S. N. M., Annaciri-Donkers, A., Crul, M., Maurer, J. M., Schimmel, K. J. M., Kemper, E. M., Hooge, M. N.L.-D., Schreuder, N., Eikmann, M., Ramcharan, A. S., Lantink, R. B., Quodbach, J., Boersma, H. H., Kelder, O., Larmené-Beld, K. H. M., Le Brun, P. P. H. & Kok, R. J., Schellekens, R. C. A., Breukels, O., Frijlink, H. W. & Gareb, B., 31-jul.-2025, In: Pharmaceutics. 17, 8, 48 blz., 1005.

Onderzoeksoutput: Article › › peer review

Heterogeneity of CD8 T-Cell Changes in Advanced Melanomas After Initiation of Immunotherapy

Hooiveld-Noeken, J. S., de Ruijter, L. K., van de Donk, P. P., Smit, L. M., Lub-de Hooge, M. N., van Sluis, J., Brouwers, A. H., Koeppen, H., Timens, W., Boersma, H. H., Elias, S. G., Gietema, J. A., Knapen, D. G., Hospers, G. A. P., Williams, S. P., Bohorquez, S. S., Ungewickell, A., de Groot, D.-J., Jalving, M. & de Vries, E. G. E., 1-jul.-2025, In: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 7 blz.

Onderzoeksoutput: Article › › peer review

Mapping the epidemiology of cancer-related anemia: A systematic scoping review of global prevalence and incidence

Elkhalifa, D., Lub-de Hooge, M. N. & Jansman, F. G., dec.-2025, In: Seminars in oncology. 52, 6, 16 blz., 152426.

Onderzoeksoutput › peer review

Metamizole induces voriconazole metabolism and results in subtherapeutic voriconazole concentrations

Baan, S. D., Touw, D. J., Lub-de Hooge, M. N. & Oude Munnink, T. H., sep.-2025, In: British Journal of Clinical Pharmacology. 91, 9, blz. 2598-2604 7 blz.

Onderzoeksoutput: Article › › peer review

Quantification of 89Zr-immunoPET: Methodological considerations.

Mohr, P., van Sluis, J., Brouwers, A. H., Lub-de Hooge, M. N., Li, Z., van Winkel, C. A. J., Lammertsma, A. A. & Tsoumpas, C., sep.-2025, In: Nuclear Medicine and Biology. 148-149, 10 blz., 109050.

Onderzoeksoutput: Article › › peer review

Pers/media

Aletta Jacobs leerstoel voor Marjolijn Lub-de Hooge

de Hooge, M.

22/12/2020

Pers / media: Overig ›

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