dr. M.N. (Marjolijn) Lub-de Hooge

Hospital Pharmacist, associate professor

m.n.de.hooge umcg.nl


Research interests

Dr. Marjolijn N. Lub-de Hooge

is a Hospital Pharmacist and associate professor at the department of Clinical Pharmacy and Pharmacology, and at the department of Nuclear Medicine and Molecular Imaging of the University Medical Center Groningen. She obtained her PhD on pharmaceutical aspects and molecular imaging of new receptor targeted drugs.

Her research mainly focuses on molecular imaging to support and optimize treatment of cancer patients with novel (targeted and immuno) therapies. She is an expert in the development, evaluation and translation of new radiopharmaceuticals and optical tracers to the clinical setting. And she is also involved in the subsequent clinical application of these new tracers for drug development, and treatment optimization: visualization of presence of drug target (patient selection), drug biodistribution (pharmacokinetics, optimal dosing, target saturation) and tumor status during treatment (early predictive biomarker, pharmacodynamics).



  1. [18F]AlF-RESCA-IL2 for imaging activated T-cells

    Antunes, I., van der Veen, E. L., Suurs, F. V., Cleeren, F., Bormans, G., Elsinga, P. H., Dierckx, R. A. J. O., Lub-de Hooge, M. N., de Vries, E. G. E. & de Vries, E. F., Oct-2019, In : European Journal of Nuclear Medicine and Molecular Imaging. 46, SUPPL 1, p. S191-S191 1 p.

    Research output: Contribution to journalMeeting AbstractAcademic

  2. Clinical-grade N-(4-[18F]fluorobenzoyl)-interleukin-2 for PET imaging of activated T-cells in humans

    van der Veen, E. L., Antunes, I. F., Maarsingh, P., Hessels-Scheper, J., Zijlma, R., Boersma, H. H., Jorritsma-Smit, A., Hospers, G. A. P., de Vries, E. G. E., Lub-de Hooge, M. N. & de Vries, E. F. J., 17-Jul-2019, In : EJNMMI Radiopharmacy and Chemistry. 4, 1, p. 15

    Research output: Contribution to journalArticleAcademicpeer-review

  3. A review of bispecific antibodies and antibody constructs in oncology and clinical challenges

    Suurs, F. V., Lub-de Hooge, M. N., de Vries, E. G. E. & de Groot, D. J. A., Sep-2019, In : Pharmacology & Therapeutics. 201, p. 103-119 17 p.

    Research output: Contribution to journalReview articleAcademicpeer-review

  4. Customary concentrations appear to be fatal: The relationship between serum digoxin concentrations and therapeutic result in patients with heart failure

    Beukema, G., Lub-de Hooge, M. N. & Kosterink, J. G. W., 10-Oct-2003, In : Pharmaceutisch Weekblad. 138, 41, p. 1440-1441 2 p.

    Research output: Contribution to journalArticleAcademicpeer-review

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  1. Marie Curie Award 2010

    Marjolijn Lub-de Hooge (Recipient), 13-Oct-2010


  2. Huizinga medal

    Marjolijn Lub-de Hooge (Recipient), 7-Nov-2019

    Prize: National/international honourAcademic

View all (2) »

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