Skip to ContentSkip to Navigation
Practical matters How to find us prof. dr. M.N. (Marjolijn) Lub-de Hooge

Research interests

Prof. Dr. Marjolijn N. Lub-de Hooge

is a Hospital Pharmacist and professor at the department of Clinical Pharmacy and Pharmacology, and at the department of Nuclear Medicine and Molecular Imaging of the University Medical Center Groningen. She obtained her PhD on pharmaceutical aspects and molecular imaging of new receptor targeted drugs.

Her research mainly focuses on molecular imaging to support drug development and to optimize treatment of cancer patients with novel (targeted and immuno) therapies. She is an expert in the development, evaluation and translation of new radiopharmaceuticals and optical tracers to the clinical setting. And she is also involved in the subsequent clinical application of these new tracers for drug development, and treatment optimization: visualization of presence of drug target (patient selection), drug biodistribution (pharmacokinetics, optimal dosing, target saturation) and tumor status during treatment (early predictive biomarker, pharmacodynamics).

 

 

Publications

89Zr-pembrolizumab imaging as a non-invasive approach to assess clinical response to PD-1 blockade in cancer

89Zr-PET imaging to predict tumor uptake of 177Lu-NNV003 anti-CD37 radioimmunotherapy in mouse models of B cell lymphoma

The Effect of Pregnancy and Inflammatory Bowel Disease on the Pharmacokinetics of Drugs Related to Inflammatory Bowel Disease: A Systematic Literature Review

89Zr-3,2-HOPO-mesothelin antibody PET imaging reflects tumor uptake of mesothelin targeted 227Th-conjugate therapy in mice

Basic aspects of good manufacturing practice for PET-rediopharmaceuticals

First-in-human study of the biodistribution and pharmacokinetics of 89Zr-CX-072, a novel immunopet tracer based on an anti–PD-L1 probody

Manual versus artificial intelligence-based segmentations as a pre-processing step in whole-body dosimetry calculations

Mesothelin/CD3 half-life extended bispecific T-cell engager molecule shows specific tumor uptake and distributes to mesothelin and CD3 expressing tissues

Modelling Tools to Characterize Acetaminophen Pharmacokinetics in the Pregnant Population

Molecular Imaging of the Receptor HER2 and the Ligand VEGF as Role Models for the Use of ImmunoPET in Drug Development

Read more

Press/media

Aletta Jacobs leerstoel voor Marjolijn Lub-de Hooge