prof. dr. M.J.H. Kas
1999: PhD degree in Behavioral Neuroscience. PhD thesis entitled “Sleep and circadian timekeeping in Octodon degus; behavioral and photic determinants of activity phase preference.” Promotors: Prof. Dr. Dale Edgar (Stanford University, California, USA) and Prof. Dr. Serge Daan (University of Groningen, the Netherlands).
1994: Master’s degree in Biology, specialization in Neurobiology, Psychopharmacology, and Ethology. Free University of Amsterdam, the Netherlands
2016-present: Professor of Behavioral Neuroscience, Groningen Institute for Evolutionary Life Sciences, University of Groningen, the Netherlands.
2012-2016: Associate Professor of Translational Behavioral Genetics, Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, the Netherlands
2004–2009: Coordinator Behavioral Genomics section, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, the Netherlands
2004: Visiting Scientist; Social, Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, London, UK. I have established an international collaboration with this department that focuses on human genetics of neuro-psychiatric disorders. I was a visiting scientist in the laboratories of Prof. Dr. D.A. Collier and Dr. Leonard C. Schalkwyk.
2003-2012: Assistant Professor and Independent Group Leader, Department of Neuroscience and Pharmacology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, the Netherlands
1999–2003: Postdoctoral Fellow, Section Neural Integration, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, the Netherlands. Supervisor: Prof. Dr. R.A.H. Adan.
1995–1999: Graduate student, Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, USA. Supervisor: Prof. Dr. D.M. Edgar and Department of Animal Behavior, University of Groningen, the Netherlands. Supervisor: Prof. Dr. S. Daan
2018: Innovative Medicine Initiative (IMI) EU grant, AIMS-2-Trials (principal investigator)
2017: ZonMW, Memorabel grant (project leader)
2017: Innovative Medicine Initiative (IMI) EU grant, EQIPD (principal investigator)
2017: ZonMW TOP grant (NWO) (principle investigator)
2016: Innovative Medicine Initiative (IMI) EU grant, ROADMAP (principal investigator)
2016: Innovative Medicine Initiative (IMI) EU grant, PRISM (project coordinator)
2016: Dutch Brain Foundation Grant, SMARD (co-investigator)
2015: Dynamics of Youth seed money grant, BeHapp (principal investigator)
2014: ECNP network grant (steering committee member)
2013: SANS project grant (principal investigator)
2012: Innovative Medicine Initiative (IMI) EU grant, EU-AIMS (principal investigator).
2010: Neuroscience and Cognition grant, University Utrecht, (principal investigator)
2009: SANS project grant (principal investigator)
2009: Wellcome trust grant, WTCCC3, (co-investigator)
2009: EFSD/MSD – European Basic Research Program (co-investigator)
2009: COST Action, SYSGENET (principal investigator)
2008: VIDI-grant ZonMW (personal fellowship)
2007: National Epilepsy Foundation Grant (co-investigator)
2006: Research grant: ABC Genomics Center (principal investigator)
2006: Marie Curie – Research training network (principal investigator)
2005: Marie Curie Fellowship (researcher in charge)
2005: NWO-British Council: UK-Netherlands Partnership Program in Science Grant (host laboratory)
2005: ZonMW grant, Early evaluation of Medical Innovations (co-investigator)
2002: EMBO fellowship (host laboratory)
1999: NWO grant (co-investigator)
Duties as a scientific expert
Topic Review co-Chair for the International Society for Autism Research 2018 Annual Meeting
Steering committee member of the ECNP Preclinical Data Network (since 2014)
Editorial Board member of Mammalian Genome (since 2012)
Panel member for review and final interviews of VENI-grants for ZonMW (2010)
Member of the management committee of an EU-COST project: SYSGENET – European systems genetics network for the study of complex genetic human diseases using mouse genetic populations (2009-2013).
Member of the Scientific Advisory Panel (Basic and Clinical Neuroscience) of the European College of Neuro-psychopharmacology (since 2009)
Member of the Scientific Program Committee for the annual ECNP congress (2015)
Selected Faculty Member of Faculty of 1000 Medicine (since 2008).
Grant reviewer for the National VENI, VIDI, and VICI program of ZonMW (The Netherlands), for the Welcome Trust (UK), for Medical Research Council (UK), and for the Israel Science Foundation (Israel)(since 2005)
Member of national and international PhD thesis review committees, including four as invited examiner in the United Kingdom (Oxford University, MRC Harwell and King’s College) and one in Lausanne (since 2003).
Peer reviewer for more than 25 journals, including Molecular Psychiatry, PLoS Genetics, Biological Psychiatry, Journal of Neuroscience, Physiological Genomics, PLoS One, Genes, Brain and Behaviour (since 2000).
Positions of trust:
Executive Committee member (since 2013) and Secretary (since 2016) of the European College of NeuroPsychopharmacology (ECNP)
Steering committee member (since 2011) and Chair (2017) of the ECNP junior scientist workshops in Nice.
Steering committee member and treasurer of the Dutch Neuroscience meeting (since 2010)
Board member and treasurer of the Dutch Neurofederation (since 2009)
Member of the organizing committee of the International Brain and Neural Genetics Society meeting (2007)
President of the Dutch Behavioral Genetics Association (since 2007).
International collaborations and positions:
2016-present: Project coordinator of the PRISM consortium which aims to unpick the biological reasons underlying social withdrawal, a common early symptom of Schizophrenia, Alzheimer’s disease and Major Depressive Disorder. This project unites 23 organisations, including researchers from European academic centres, a patient family organisation, and major pharmaceutical companies
2014-present: Steering committee member of the ECNP Preclinical Data Network that aims to provide a forum for preclinical data sharing and interpretation to enhance its utility for clinical research and drug development.
2012-present: EU-AIMS consortium member which is a novel collaboration between organisations that represent affected individuals and their families (Autism Speaks), academia and industry. The aim is to join forces for the development and assessment of novel treatment approaches for autism. As Principal Investigator in this grant, my role is to contribute translational phenotyping methods (from mouse to human).
2011-2013: International collaboration with Prof. Dr. N. Yamamoto, Laboratory of Cellular and Molecular Neurobiology, Graduate School of Frontier Biosciences, Osaka University, Suita, Osaka, Japan
2007-present: Member of the Genetic Consortium for Anorexia Nervosa (GCAN). GCAN represents researchers and clinicians from 16 countries around the world. I have been actively involved in the study-design and the stratification of phenotype data from patients and controls. The first results of this global cooperative effort were released early 2014 (Molecular Psychiatry, 2014).
2010-2012: International collaboration with Prof. Dr. R. Williams, Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, Tennessee, USA
2009-2013: Management committee member of SYSGENET, an EU-funded action for the establishment of system genetics approaches in mice to unravel complex human diseases. In this role, I executed a number of dedicated workshops, management committee meetings, and exchange programs to build a system genetics infrastructure in Europe.
2004: Visiting Scientist at the Institute of Psychiatry, London, UK (Social, Genetic and Developmental Psychiatry Research Center). I have established an international collaboration with this department that focuses on human genetic research of neuro-psychiatric disorders. I took this initiative to build a bridge between animal and human research, bringing my expertise from the development of rodent models to the domain of human disease. As part of this collaboration, I was a visiting scientist in the laboratories of Prof. Dr. D.A. Collier and Dr. Leonard C. Schalkwyk for two months. In addition, we continue to exchange students and PhD students to further integrate our observations from both human and mouse genetics.
1995 – 1999: PhD research performed at Stanford University, Palo Alto, California, USA (Department of Psychiatry and Behavioural Sciences). Supervisor: Prof. Dr. D.M. Edgar. I performed my Ph.D. research at Stanford University (California, USA) for four years. Here, I investigated the neurobiology of EEG sleep-wake regulation in mammalian rodent species by using longitudinal electrophysiological and automated behavioural observation methods. Furthermore, I studied the neurophysiology of photic and of behavioural control of circadian timekeeping in these species.
Invited seminars (a selection from over 50 lectures in chronological order):
2014: Seminar series on biological mechanisms and biomarkers of child psychiatric disorders, University of Frankfurt, Germany; ‘Dissecting Autism heterogeneity in developing mice.’
2010: Swedish Medical Genetics Society, University of Uppsala, Sweden; ‘Animal model systems in psychiatric disease.’
2008: Lausanne Neurobiology Seminars, Lausanne, Switzerland. ‘Genetics of behavioural domains across the neuropsychiatric spectrum; of mice and men’
2008: Keynote speaker at the ECNP Workshop on Neuro-Psychopharmacology, Nice, France. ‘Novel approaches in behavioural genomics research’
A selection of other international lectures:
2018: European Congress of Psychiatry, Nice, France
2017: ECNP congress, Paris, France
2017: ISCTM Autumn meeting, Paris, France
2017: British Association for Psychopharmacology, Harrogate, United Kingdom
2017: ECNP Innovation meeting, Nice, France
2016: ECNP congress, Vienna, Austria
2015: Max Planck Institute Munich, Germany
2015: International Summer school of Neuroscience, Catania, Italy.
2014: Annual Conference of the German Genetics Society, Munsbach, Luxembourg.
2014: FENS Summer School on Neurodevelopmental Psychiatric Disorders, Bertinoro, University Center Of Bologna, Italy.
2013: Medical Research Council Harwell, United Kingdom.
2012: Scientific meeting Sysgenet, Bilbao, Spain.
2012: European College of Neuro-Psychopharmacology Congress, Vienna, Austria.
2011: Osaka University, Osaka, Japan.
2011: International OCD meeting, Vancouver, Canada.
2010: European College of Neuro-Psychopharmacology International Congress, Amsterdam, the Netherlands.
2010: EU-Casimir policy meeting, London, United Kingdom.
2009: Eating Disorder Research Society meeting, Brooklyn, New York, USA.
2009: European College of Neuro-Psychopharmacology International Congress, Istanbul, Turkey
2007: Institute of Psychiatry, London, United Kingdom.
2005: European College of Neuro-Psychopharmacology International Congress, Amsterdam, the Netherlands.
2004: European Winter Brain Conference, France.
2003: European Brain and Behaviour Society, Barcelona, Spain.
2003: International meeting of eating disorders, Florence, Italy.
2002: European College of Neuro-Psychopharmacology International Congress, Barcelona, Spain.
2000: Society for Research on Biological Rhythms, Jacksonville, Florida, USA.
Organizer symposia and targeted expert meetings:
2017: Organised and Chaired the ECNP Innovation meeting "New approaches to psychiatric drug development", Nice
2015: Drug discovery in Neuroscience: Translatability of preclinical data, ECNP congress, Amsterdam.
2014: Organized and chaired a symposium, entitled, ‘Targeting synaptic defects in Autism Spectrum Disorders’, at the Dutch Neuroscience Meeting, the Netherlands.
2013: Organized and chaired a three-day workshop on ‘Genetic Mouse Models for Human Disease’; financed by the International Neuro-Informatics Coordinating Facility.
2011: Organized and chaired an International Workshop on Cross-species analysis of Schizophrenia in Helsinki financed through the EU-COST action Sysgenet.
2010: Organized and chaired a session, entitled, The Neurobiology of eating disorders, at the European College of Neuro-Psychopharmacology Congress, Amsterdam, the Netherlands.
2009: Organized and chaired a session, entitled, Genetic regulation of behavioural domains across the neuropsychiatric spectrum: of mice and men at the European College of Neuro-Psychopharmacology Congress, Istanbul, Turkey.
2009: Organized and chaired a two days Targeted Expert Meeting on Translational research for Psychiatry at the European College of Neuro-Psychopharmacology Congress, Istanbul, Turkey.
2008-2011: Organized and chaired the yearly Dutch Behavioral Genetics meeting, the Netherlands.
2006: Organized and chaired a session, entitled: the genetic dissection of complex behaviours, of mice and men at the European Winter Brain Conference, Switzerland.
2004+2005: Organized and chaired the Brain Center Rudolf Magnus Summer school, Utrecht, the Netherlands.
2004, 2006, 2007, 2009, 2011, 2012, 2014, 2016, 2017: Organized and chaired symposia at the Dutch Neuroscience Meeting.
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